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    Blood components and their

    function

    BIS, Grade 8, Biology

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    Lesson overview

    1. Answer the warm up questions on the worksheet

    2. Discuss as a large group your ideas about blood.

    3. Organization of the work phases

    4. Independent study: work alone to identify relevant factson blood components based on a reading.

    5. Group work: Share your findings and will work in theirgroups to solve a graphic organizer based on their

    individual reading.6. Whole class review of the graphic organizer

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    the average human has 5 litres ofblood, which is approximately 8% of anadult's body mass. Difference is mainlydue to the differences in body size.

    it is a transporting fluid

    it carries vital substances to all partsof the body

    Blood facts

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    Blood facts II

    Its mean temperature is 38 degrees Celsius.

    It has a pH of 7.35-7.45, making it slightly

    basic. Blood in the arteries is a brighter red than

    blood in the veins because of the higher levelsof oxygen found in the arteries.

    An artificial substitute for human blood hasnot been found.

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    Blood composition

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    What makes up our blood?

    RED BLOOD CELLS (Erythrocytes) The most

    abundant cells in our blood; they are produced in thebone marrow and contain a protein called hemoglobinthat carries oxygen to our cells.

    WHITE BLOOD CELLS (Leukocytes) They are part ofthe immune system and destroy infectious agents calledpathogens.

    PLASMA This is the yellowish liquid portion of bloodthat contains electrolytes, nutrients and vitamins,hormones, clotting factors, and proteins such as

    antibodies to fight infection. PLATELETS (Thrombocytes) The clotting factors that

    are carried in the plasma; they clot together in a processcalled coagulation to seal a wound and prevent a loss ofblood.

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    Blood Facts

    The average adult has about FIVE liters of bloodinside of their body, which makes up 7-8% of theirbody weight.

    Blood is living tissue that carries oxygen andnutrients to all parts of the body, and carries carbondioxide and other waste products back to the lungs,kidneys and liver for disposal. It also fights against

    infection and helps heal wounds, so we can stayhealthy.

    There are about one billion red blood cells in two tothree drops of blood. For every 600 red blood cells,there are about 40 platelets and one white cell.

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    Blood

    plasma (55%) blood cells (45%)

    water (92%) dissolved

    particles (8%)

    proteins, fats,

    vitamins, urea,glucose,

    minerals,

    white blood cells

    (= lykocyctes)

    life span 3 -4 days;

    4-10 thousand per

    ml of blood.

    platelets (=

    thrombocytes)

    life span under 7

    days;200 400 thousand

    per ml of blood

    red blood cells (=

    erythrocytes)

    live about 120 days;

    4 -5 millions per ml of

    blood; made in the

    bone marrow

    transport of

    nutrients, waste

    products and blood

    cells

    transport of

    oxygen

    defending the

    body against

    pathogens

    (immune system)

    blood clotting

    and repair of

    damaged tissue

    Components

    Function

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    Human blood smear

    X 500

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    plasma (55%)

    red blood cells

    (5-6-million /ml)

    white blood cells

    (5000/ml)

    platelets

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    Plasma

    liquid part of blood

    plasma transports:- soluble foodmolecules

    waste products

    hormones antibodies

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    White blood cells

    the bodies defence

    part of the immune system

    much larger than RBCs

    far fewer have a nucleus

    4000-13000 per mm3

    2 typesphagocytes and lymphocytes

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    Platelets

    if you get cut:- platelets produce

    tiny fibrin threads these form a web-like

    mesh that traps bloodcells.

    these harden forming

    a clot, or "scab." 150,000 to 400,000per mm3

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    Blood clotting

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    Haemophilia (also

    spelled hemophilia) is

    genetic disorders that

    impair the body's

    ability to control blood

    clotting

    Like most Xchromosome

    disorders,

    haemophilia is morelikely to occur in

    males than females.

    Haemophilia has featured

    prominently in European

    royalty and thus is

    sometimes known as "the

    royal disease".

    Queen Victoria passed

    haemophilia on to some of

    her descendants.

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    RBCs and a WBC

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    The number of

    leukocytes in theblood is often an

    indicator of disease.

    Leukemia (AmericanEnglish) or leukaemia(British English) is atype of cancer of theblood or bone marrowcharacterized by anabnormal increase ofwhite blood cells.

    Due to the increased

    production, the bonemarrow is unable toproduce healthy WBCs.

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    Red blood cells specialisations

    2) no nucleus

    extra space inside

    3) contain haemoglobin

    the oxygen carryingmolecule

    250million molecules/ cell

    1) biconcave shape

    increases thesurface area somore oxygen can be

    carried

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    Haemoglobin

    gives red bloodcells their colour

    can carry up to

    4 molecules of O2

    associates and

    dissociates with O2

    contains iron

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    Microscopic

    Views

    Bird Blood

    Cat Blood

    Dog Blood

    Fish Blood

    Frog Blood

    Snake BloodHuman Blood

    Horse Blood

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    Summary questions

    Can you state the composition of Blood?

    state the function of red blood cells and

    plasma? explain the function of haemoglobin in the

    transport of oxygen?

    state the function of WBCs?

    explain how blood clotting works?

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    Blood pie chart

    Water

    Dissolved particles

    RBC

    WBC

    Platelets

    50.6 (92% of 55)

    4.4

    42.75 (95% of 45)

    1.125 (2.5 % of 45)

    1.125