Brain & How We Learn

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    MINISTRY OF BASIC EDUCATION, SPORT AND CULTURE

    COMPENSATORY TEACHING

    FACILITATORS WORKSHOP

    2001

    1

    HOW WE LEARN:

    THE ROLE OF THE CENTRAL

    NERVOUS SYSTEM

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    HOW WE LEARN.INTODUCTION:

    We know there is an interplay between what we have inherited form our bloodline, what happens during or after birth and ourenvironment (Nature and Nurture). But, we have to know what happens with all the stimuli from the environment that bombards us,and why some of us cannot cope with it.

    The brain is the centre where all stimuli is received, processed and given meaning to. Learning is a process of sensory input,

    processing of information which takes place in the brain and output which is in the form of any kind of motor movement (speech,writing, performance,.

    INPUT PROCESSING: OUTPUT:Eyes The Central Nervous System, Movement (e.g. speechEars production, writing,Tactile (touch) performing a task, etc.)Kinesthetic (feeling of movement)

    Not nearly all of the functions of the brain have been explored, but a number of advances have been made over years. It is known thatthe brain can be roughly divided into structurally functional areas, that these areas work in an integrated fashion and that it can bedetermined by technical devices and substance injections. Usually the functional areas are numbered.

    Studies include imaging of the brain to determine activity or increased blood-flow during particular tasks to show the involved areasof the brain. These scans can also indicate diseased areas like brain tumors, and structural abnormalities. The following are acronymsfor brain imaging: CT is an X-ray type of scan of brain structures and then imaged on a computer, EEG, EP & MEG graphs forelectrical brain activity of different brain structures, MRI applies a strong magnetic field to the brain to study smaller brain structuresand nuclei, PET, CBF and SPECT are all used in the imaging for region blood metabolism where activities take place.

    We will try and give simple pictures and descriptions of the areas and functions of the brain, hemispheric dominance, and neuro-biochemistry.

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    Hemispheres

    The brain is divided into a left hemisphere and right hemisphere. These two sides are connected by the corpus callosum. (see later)

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    LEFT RIGHT

    C o r p u s

    C a l

    l o s u m

    Right Brain functions

    NON-VERBAL Gestalt/ Holistic images, shapes,

    pictures) Sense of continuation of existence

    over time (past, present, future) 3-Dimensional images / depth Colours and hues Pitch, accent, sound, melodies Non-verbal language (body-

    language/ read between the lines)/ hidden communication

    Left Brain functions

    VERBAL Realistic Detail as in words, analysis Logical sequence/order as letters in

    words, numbers, sequential facts, etc Read Speak Write Speaking

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    We tend to develop our left hemisphere more that the right hemisphere due to ourexposure to language. Instead we should integrate functions of both hemispheres, e.g.use more melodies in teaching, use colours, visualise pictures in your mind, think of ourselves another time or place, try to read what people think by watching their bodylanguage and facial expressions,. That is why teachers should integrate brain functions

    when teaching.

    The two halves of the brain are further divided into four parts: (The right side issimilar to the left side)

    The Pre-frontal Lobes

    The Parietal Lobes

    The Occipital Lobes

    The Temporal Lobes

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    Inside the brain The Cortex Process information. Decision and initiation of

    concrete action Receptive language and

    speech functions Storing and recalling

    Eye

    Pre-frontal cortex: Planning Insights

    Empathy

    Introspection

    Intuision Decision on action

    Control of

    The Limbic system :

    Biochemical centre.

    Control pain sensation.

    Emotional arousal.

    Plays a role in:memory(hippocampus), instinctivebehaviour, impulse control,

    perseveration, frustrationtolerance, temperature, hunger,arteries, etc

    The Hind-brain: Movement Balance Muscle tone & control in

    keeping the posture correct Arouse and relax muscle

    groups to perform amovement.

    The Brainstem Respiratory Functions Cardiovascular functions Sleep and consciousness Contain cell-bodies for

    sendingneurotransmitters tohigher brain centres

    Reticular Activating System(RAS) Carry ascending and

    descending neurons andCranial nerves

    Alertness andwakefulness

    May involve motivationto do something.

    Pons

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    The Limbic System Parts

    1. Hippocampus & Amygdala

    2. Basal Ganglia

    3. Thalamus

    Main Functions: Memory

    The right side: memory forspatial orientation/position, etc.

    The left side: memory for verbalmaterial

    In lesser degree in right side:memory for sentences (contentscan be visualised).

    Memory for acquiring motorsequences

    Involved in neurochemistry The Am dala is associated

    Main Functions: Motor functions, posture,

    muscle tone, normal movement If damaged (twitches, jerks,

    tremors) Sequencing of movement,

    smooth movements (e.g. as intalking)

    Main Functions:

    The General Post Office Receives, sends, selects,

    integrates messages to and frombrain areas.

    Is the centre of arousal Works with the somato-sensory

    Hippocampus

    Amygdala

    Olfactory

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    Pre-frontal lobe

    S u p p

    l e m e n

    t a r y m o t o r

    P r e - m o t o r c o r t e x

    M o t o r c o r t e x

    S o m a t o s e n s o r y c o r t e x

    Parietal lobe

    P r i m a r y a r e a

    A s s o c

    i a t i o n a r e a

    Auditoryassociation

    Brocasarealeft side

    Wernickes area left

    side

    Temporal lobe

    Occipital lobe

    Visual cortex

    Primary area

    Association area

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    468

    9

    10

    1147

    4645

    44

    321

    57

    4340

    4142

    38

    22

    2137

    39

    1918

    17

    6

    24

    33

    2511

    10

    9

    8

    4 57

    3123

    26

    29 30

    12

    3 1 2

    19

    18

    17

    181937

    20

    36

    4827

    3528

    34

    38

    Brodmans Cortical Areas

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    Frontal Lobe Areas

    Frontal Lobe problems Irritability and labile emotions, depression and flatness of affect, lack of motivation, difficulty with attention and concentration no:

    10) A peculiar sense of humour Brocas aphasia (problems in motor production of speech) Memory problems and other higher cognitive functions, e.g. reflection, meta-cognition , abstract thinking, planning, programming,

    judgement, verification

    10

    46

    8 64

    45 44

    47

    11

    Frontal Lobe Functions

    There is reciprocal connections with motor-sensory (no 4)and emotional areas.

    Responsible for controlling contro-lateral movements (6)

    Articulation /Speech production (no 44) and writing in thedominant hemisphere.

    Eye movements (no 8) This lobes functions are critical to personality and

    behaviour, abstract thinking, planning, programming,memory, judgement, verification and higher mental

    43

    10

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    Difficulty in distal movement such as writing, speech, eye-movements, face, etc. (fine motor movements) as well as speed andstrength of movement. (no 4)

    Poor body and limb movement (parietal cortex) (nos 4, 6, 8), to alter movements, or to make a series of smooth movements(nos : 5, 7).

    Cannot plan movement, but know how it should be done ( no: 6) A learner has difficulty to learn through movement. No voluntary gaze (nos : 8, 9) Total inhibition or no inhibition of response (inappropriate or uninhibited behaviour) (nos: 9, 10, 11) Aphasia ( a language disorder) (no: 44). Cannot put matter into series, sequential order (no: 46). Cannot put letters or sounds into sequence to form a word, or words into

    sentences, counting in correct order or tell a story in a sequence of events. Problems with orientation in space (no: 47). Cannot find his/her way from one place to another, cannot read maps, difficulty to

    write between lines, turns letters and numbers upside-down . Problems with association (integrated function) Problematic social behaviour (no: 11) Does not know ethics in behaviour, hyper-active and uncontrollable, impulsive behaviour,

    seen as naughty or unmannered. Poor olfactory discrimination (no: 45). Cannot learn through tasting and smelling

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    The Parietal Lobe Areas

    Parietal Lobe problems Problems to discriminate tactile stimuli (e.g. through touch) (nos: 1, 2, 3). Inability to attach meaning to sensory Visual and tactile impressions (agnosia) (nos: 5, 7, 37) Left side: Cannot deal with or manipulate objects intelligently (constructional apraxia) (nos 7, 40) Left side: Language and Math problems (nos: 39, 40) Short term memory problems (nos: 37, 40)

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    1

    5

    7

    404339

    37

    Parietal Lobe Functions Receives and identifies sensory information from

    tactile (touch/skin) receptors (nos: 1, 2, 3, 5, 7) Processes visual and auditory sensations and Praxes

    (perception of speed and movement?) (nos: 7, 22,37, 39, 40)

    Reaction to pain sensation (no: 43 ??) Awareness of and response to illness (nos 7, 40

    right) Naming body parts (no:5, 7) Tone, melody, rhythm, tempo (nos: 42,22 right) Identif meanin of non-verbal sounds (nos 42, 22

    22

    12

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    Problems with body image ( no: 7) Cannot name body parts, own or others gender, poor human figure drawings. Left-right confusion, (no: 7, 40) Child will have difficulty identifying left and right on his/her own body (laterality), confuse

    directions, b/d/p confusion, and reads or writes in the wrong direction . Right hemisphere : Spatial problems (no 7, 40) (see frontal lobe spatial problems as well) Problem with eye-movement (nos: 7, 40) Mis-reaching objects (nos: 5, 7) In either or both hemispheres: Right-left disorientation, finger agnosia (through finger touch) , astereogosis (touching solid

    objects) In dominant hemisphere: Alexia (inability to read), agraphia (inability to write), anomia (difficulty to recall the names of things),

    ideomotor and kinesthetic apraxia (difficulty to execute a task or movement on command), dyscalculia (loss of ability to docalculations)

    In the non-dominant hemisphere: impaired spatial abilities, denial of illness (anosognosia), inability to recognise body parts(autopagnosia), dressing oneself, constructional and kinesthetic apraxias (difficulty in completing a task or , to execute a task ormovement on command) left-side spatial neglect.

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    The Occipital Areas

    Occipital Lobe problems

    Disturbed spatial orientation (see frontal lobe and parietal lobe problems) Visual illusions Visual hallucinations Blindness Hysteria symptoms

    17

    181921

    20

    Occipital Lobe Functions Processing of visual images (no:

    17) Perception, integration, imprinting

    of visual information Selection, interpretation and

    memory/recall of visualinformation (nos: 18, 19, 20, 21,37)

    Right lobe: Perceptual organisation Left Lobe: Visual language

    reception Naming, using, recognition of

    objects no: 18, 19, 20, 19 left &corpus callosum)

    Recognising drawn objects (nos:18, 19, 20, 21 right)

    Face recognition (nos:18, 19 right)

    Associate colour with objects (nos:18, 19 right)

    Naming colours (nos: speech areas+ 18, 19, 37)

    Recognising hues (Nos: 18, 19,

    22

    37

    14

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    15

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    The Temporal Lobe Areas

    Temporal Lobe Problems

    Memory impairment (bilateral) (no 21) Left side: Language comprehension (no.: 22) Control of sexual and aggressive drives (Limbic system) Wernickes aphasia (dominant hemisphere) when speech is fluent and spontaneous, but incoherent and non-sensical Klver-Bucy syndrome (placidity, apathy, hyper sexuality, visual &auditor agnosia, amnesia, aphasia, dementia, seizures) Aprosody (non-dominant hemisphere)( cannot inflect own speech with affect or comprehend inflections of other speech)

    41

    4252

    38

    Temporal Lobe Functions Hearing, sound discrimination, language skills (no:

    41). Selection of auditory input, e.g. organising verbal

    information into categories (no: 38) Differentiation of sound sequences, pitch and

    rhythm (Left lobe: Wernickes area forinterpretation, speech comprehension and memory.

    Right lobe: non-verbal perception, e.g. melodies)(nos: 22, 42)

    Long term memory (especially hippocampus) (no:21 - see Occipital lobe)

    Sexual and aggressive behaviour Left side: Comprehension of Language (no: 22) Interpretation of gustatory and olfactory sensations Major component of limbic system

    22

    21

    Wernickes area

    16

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    Integrated Functions of the Temporal, Occipital and Parietal lobes

    Translation of information Memorising Comprehension, association and expression Organisation of complex, simultaneous responses, e.g. essay writing which involves strings of thoughts, language, encoding into

    equivalent graphemes, recall of the letter symbols, verify correct spelling and syntax, transferring these into kinesthetic patterns activation of different nerves and muscle groups and motor movement (writing)

    Internal spatial organisation according to body-in-space awareness and spatial orientation according to input from auditory, visualand tactile-kinesthetic modalities.

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    Example of areas that function for Language

    Hear and comprehend word:

    Spoken word Areas 41, 42 Wernicke (area 22)

    Speak

    Cognition Wernicke Broca Face Cranial nerves

    Read

    41

    4252

    22Wernickes area

    44Brocas area

    4

    321

    39 F a c e

    19 18

    17

    18

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    Written word Area Areas 18, 19 Area 39 Wernicke

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    Major structures involved in Reading and Spelling

    Left hemisphere only Phonetic reading and spelling

    Right hemisphere only Grapheme reading and spelling

    Broca left & Wernicke right Phonetic spelling - grapheme reading

    Wernicke - left & Broca right Phonetic reading grapheme spelling

    Weak left or right Broca Poor phonetic or grapheme spelling

    Weak left or right Wernicke Poor phonetic or grapheme reading

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    Hemispheric dominance

    The two hemispheres are connected by the corpus callosum. The dominant hemisphere isthe hemisphere that is organised to express language. The left hemisphere is regarded asthe dominant one in 97% of the population, including 99% of right-handed persons and60 70% of left-handed persons. Language dominance is therefore not completelysimilar to hand dominance. There are also cases of mixed dominance for language, as inthe case of hand-dominance.

    Normally, in a right-handed person the left hemisphere is dominant and the motorpathways cross through the corpus callossum.

    Hand-dominance and WritingLeft-handed person Right-handed person

    LEFT RIGHT

    C o r p u s

    C a l l o s u m

    motor area

    somato-sensory area

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    Hearing

    Lift up yourhand

    LEFTRIGHT

    C o r p

    u s

    C a l

    l o s u m

    LEFT RIGHT

    C o r p u s

    C a l

    l o s u m

    4, 6 4, 6

    22, 39, 40 22, 9, 40

    Hearing and Performing an action: Damage to pathways

    22

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    23

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    Smelling and identifying: Damage to pathways

    Vision

    Vision also has a crossed system, therefore there may be eye-dominance too.

    LEFT

    RIGHT

    LEFT RIGHT

    C o r p u s

    C a l

    l o s u m

    22, 39, 4022, 39, 40

    rose

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    The right sides of the eyes will see one part of an image and send messages to the right,back side of the brain. The left side will see the other part and send messages to the left,back side of the brain

    Vision, and damage to pathways

    LEFT

    RIGHT

    man

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    Brain Biochemistry

    Brain biochemistry refers to substances in the brain that transmits messages (impulses) toareas of the brain . The substances are called neuro-transmitters or neuro-messengers

    Chemical neurotransmission:Without going into detailed descriptions and intricate processes, nerve impulses areconverted into a chemical signal in the pre-synaptic neuron. This is a release of neurotransmitters by the pre-synaptic neuron and the detection of this transmitter byreceptor proteins. At the synapse where two neurons meet, messages are carried over acleft to enter the next neuron through receptors.

    Receptors are proteins in the pre-synaptic or post-synaptic neuronal membrane, andspecifically recognise neurotransmitters.

    There are basically three types of neurotransmitters that can be found in a single neuron: monoamines ( dopamine, norepinephrine, epinephrine, serotonine, acetylcholine,

    histamine) amino acids peptides

    Alterations in the amounts of released neurotransmitters can influence learning,behaviour or other conditions.

    Dopamine imbalances are linked to schizophrenia, Parkinsons disease Manic-depressive mood disorders.

    An imbalance in Norepinephrine has been linked to depression . An imbalance in Serotonin has been linked to mood disorders, anxiety disorders

    (including obsessive-compulsive disorders), violence and schizophrenia Acitylcholine has been linked to movement disorders (Parkinsons disease,

    Huntingtons chores and Tardive dyskinesia) as well as mood and sleep disorders,depression.

    Histamine has been linked to allergic reactions, sedation, weight gain, hypotension. Certain Amino-acids have been linked to anxiety, epilepsy, Huntingtons chorea,

    Parkinsons disease. Different Peptides have been linked to regulation of pain, mood, eating an movement

    disorders,

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    Neuro- endocrinology

    Hormonal messages are carried from the hypothalamus to the pituitary gland whereadditional hormones are secreted, e.g. cortisol (or blocked) and so on.The hormone vasopressin is involved with blood-pressure, fluid and electrolyte balance.It can be stimulated by pain, stress and certain drugs and is inhibited by alcohol.Endocrine disorders can be seen in some psychiatric patients, e.g. Cushings syndrome,depression and suicide attempts, hypomania, emotional lability, , disturbance of thegrowth hormone.

    Pons

    Dopaminergic pathways:

    Noradrenergic pathways:

    Serotenergic pathways:

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    Psycho-immunology The immune system reciprocally interacts with the nervous and endocrine systems.Damage to parts of the limbic system and the pituitary gland can result in dysfunction inthe immune system.

    It is thought that either an infection may influence the immune response negatively orthat an abnormal immune system allows the infection to develop.

    Symptoms may include depression, insomnia, emotional lability, nervousness, andconfusion. T-cell prolifiration was found to proliferate in bereaved persons. Stress,loneliness and poor coping skills is another cause