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DASSAULT SYSTEMESBIOVIA

Headquartered in San Diego, California, Dassault Systèmes Biovia Corp. (BIOVIA) provides a scientific collaborative environment for advanced biological, chemical and materials experiences supporting science- and process-based industries.

BRAND PROFILEDATASHEET

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BIOVIA—VIRTUAL BIOSPHERE AND MATERIALSBIOVIA solutions create an unmatched scientific innovation environment that can help science- and process-driven companies develop better products faster and more cost effectively. The industry-leading BIOVIA portfolio integrates the diversity of science, experimental processes and information requirements from discovery to manufacturing with proven capabilities in:

• Collaborative Science—Faster discovery through improved multi-disciplinary collaboration, modeling and simulation, data management/informatics and decision making for biologics, chemicals and materials

• Unified Lab Management—Increased efficiency and compliance through standardized, role-based, end-to-end laboratory workflows built on a single technology foundation. This enables scientific teams to manage laboratory resources, processes and interfaces while sharing data and information internally across the organization and externally with partners

• Process Production Operations—Improved understanding of critical process drivers with validation-ready process and quality data access, aggregation, contextualization, analysis and reporting

• Quality and Regulatory Management—Enhanced support for global quality content, policies and procedures along with comprehensive document and process management capabilities

BIOVIA solutions are used by more than 2,000 companies in the Life Sciences, Energy/Process/Utilities, Consumer Packaged Goods/Retail, Transportation/Mobility and High Technology sectors, as well as academic and government entities. Customers include 25 of the top 25 pharmaceutical companies, 25 of the top 25 biotech companies, 20 of the top 25 chemical companies, 4 of the top 5 consumer packaged goods companies, 5 of the top 10 oil and gas companies and 3 of the top 5 aerospace companies.

PRODUCTS AND SERVICES

BIOVIA FoundationThe BIOVIA Foundation is the basis of our software and services offerings and is central to our strategy to develop and deliver scientific product lifecycle management software.

The BIOVIA Foundation’s open, scientifically aware, service-oriented architecture allows organizations to integrate and deploy broad scientific solutions spanning data management and informatics, enterprise lab management, modeling/simulation and workflow automation. The BIOVIA Foundation leverages our deep domain expertise in chemistry, biology and materials science, informatics, predictive science, digital laboratory management, process data analytics and regulatory compliance and quality. BIOVIA’s foundational technology manages structured and unstructured information encountered early in the innovation cycle, as well as highly structured data from quality and manufacturing.

Collaborative Science

Scientific Pipeline Design and Execution• BIOVIA Pipeline Pilot: Built on the BIOVIA Foundation,

BIOVIA Pipeline Pilot enables scientists to rapidly create, test and publish scientific services that automate the process of accessing, analyzing and reporting scientific data. Pipeline Pilot protocols automate the scientific analysis of data and enable researchers to rapidly explore, visualize and report results.

• BIOVIA Component Collections: Extensive scientific Component Collections rapidly and cost-effectively deliver advanced imaging, modeling and analytics capabilities supporting scientific workflows from discovery to manufacturing.

Life Science and Materials Science Predictive AnalyticsBIOVIA modeling and simulation software allows scientists to perform computations of chemical, biological and materials properties; to simulate, visualize and analyze chemical and biological systems; and to communicate the results to other scientists. Scientists can investigate and test hypotheses in silico prior to costly experimentation, reducing the time and expense involved in bringing products to market.

• BIOVIA Discovery Studio: This life science modeling and simulation application, which is built on the BIOVIA Foundation, enables scientists to engage in scientific exploration from target identification to lead optimization using a wealth of trusted life science modeling and simulation tools.

• BIOVIA Materials Studio: This materials modeling and simulation application, now also integrated with the BIOVIA Foundation, enables researchers in materials science and chemistry to predict and understand the relationships of a material’s atomic and molecular structure with its properties and behavior.

Research ApplicationsBIOVIA is also a leading provider of software-based solutions designed to capture, store, manage and mine scientific data and information, both on premises and in the Cloud. Through this combined portfolio, we provide comprehensive data visualization and analysis software enabling scientists to search, retrieve and use chemical structures, biological and chemical data, experiment data, registration information and more.

• BIOVIA Insight: This next-generation Life Sciences informatics solution for interactive searching, browsing and visualizing data lets scientists filter data and results by scientifically relevant criteria, accelerating query refinement across a broad range of scientific objects. With increased insight into their data, scientists can make fast, informed decisions about how to move research projects forward.

• BIOVIA Registration: A flexible, fully featured, out-of-the-box solution for building, managing, and searching a corporate substance and batch database and for defining, registering, querying, and reporting on biological entities.

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• BIOVIA Chemical Content Databases: This comprehensive, integrated and cross-referenced collection of factual databases and reference works covers chemical sourcing, molecular properties and bioactivity (metabolism and toxicology) information. These resources can be accessed through ELN, data management and informatics applications or via the Internet through the DiscoveryGate portal.

• BIOVIA ScienceCloud: Collaboration, Externalization, Cloud. With no software to manage and no hardware to maintain, this technologically innovative information management and collaboration workspace in the Cloud enhances operational excellence and collaborative discovery for globally networked drug research partners.

Systems Biology & Integrative TherapeuticsThis comprehensive suite of BioKnowledge solutions addresses the innovation and performance challenges of today’s biopharmaceutical industry by providing capabilities supporting global scientific collaboration, scientific content federation, semantic search, virtual modeling and predictive simulations.

Unified Lab ManagementSupported by the BIOVIA Foundation, BIOVIA Unified Lab Management capabilities drive streamlined, more efficient lab workflows, harmonization and standardization and fully integrated and automated, easy-to-deploy processes. Functioning as an integration hub, the BIOVIA Foundation not only integrates the BIOVIA applications but also all major third-party systems and instruments. The BIOVIA Foundation also supports seamless data transfer between the different domains from Research to Manufacturing and with external collaborators.

• BIOVIA Workbook: BIOVIA Workbook is a multi-disciplinary electronic lab notebook (ELN) for documenting and managing the flow of information, tasks and materials within and between labs. BIOVIA Workbook includes strong integration capabilities and workflow support in addition to authoring, collaboration and IP protection capabilities. The notebook offers scientists across multiple disciplines the opportunity to streamline experiment planning, design, execution, analysis and reporting, particularly in regulated environments.

• BIOVIA Notebook: BIOVIA Notebook is an easy-to-deploy, easy-to-use ELN for organizations focused on intellectual property capture and information sharing, process documentation and overall lower total cost of ownership. It is offered as both an enterprise level, on-premises, server-based installation and via a SaaS model targeted for small- and medium-sized businesses and academic markets.

• BIOVIA LES: An electronic environment for procedure execution in the laboratory, removing paper processes and automating the interaction with methods, instruments and supplies that scientists and analysts use every day in regulated environments.

• BIOVIA EBR: An out-of-the-box system that automates the execution and review of batch records. BIOVIA EBR improves regulatory compliance for smaller organizations or sites while avoiding the large overhead of a complex Manufacturing Execution System.

• BIOVIA LIMS: BIOVIA’s process- and execution-driven approach to LIMS deployments is fundamentally different from the sample-driven approach of traditional LIMS and eliminates the complexities, excessive customization and lengthy associated validation requirements inherent with legacy LIMS. Applications include: environmental monitoring, inventory management, instrument metrology/calibration management, sample management, stability management and work request management.

• BIOVIA Compose: provides a standards-based approach to procedure authoring that enables the right content to be input into processes from the beginning. By ensuring that new product development processes and analytical methods are reliable and repeatable across global sites, BIOVIA Compose increases process efficiency, reduces cycle times, improves product/process quality and enhances compliance.

• BIOVIA Capture: is a dedicated application supporting execution procedures such as recipes and methods in the lab. Designed for mobility, the application increases efficiency, reduces transcription errors, supports standardization and improves compliance.

• BIOVIA Experiment: Designed specifically for research and development, BIOVIA Experiment enables scientists to efficiently plan and execute experiments, record and analyze data with powerful queries and visualization, generate flexible reports and rapidly mine knowledge from experiments and data. The software provides interoperability with existing lab equipment and applications and offers features for improving experimentation management and collaboration.

• BIOVIA CISPro: Offered as both an on-premises and a Cloud-based solution, the BIOVIA CISPro Chemical Inventory Management System makes current, real-time chemical safety and inventory data available on-demand, helping to drive safe chemical handling, storage and management. This EH&S compliance software helps companies adhere to federal, state and regional regulatory and safety requirements, supporting the sustainability initiatives of customers in almost every industry.

Process Production OperationsProcess Production Operations software from BIOVIA drives improved quality and process robustness through product and process monitoring and continued process verification (CPV) to improve quality and lower compliance costs.

• BIOVIA Discoverant: This solution provides process development, quality, and manufacturing specialists with self-service, on-demand access to process and quality data from disparate databases and paper records. The software automatically aggregates and contextualizes the data, enabling statistical investigations with automated validation-ready workflows for teams across different organizations. Improved visibility into process data improves overall process understanding.

Quality and Regulatory ManagementAvailable as SaaS, private Cloud or on-premises deployments, BIOVIA’s comprehensive document and process management capabilities scale to thousands of users and millions of documents, while supporting externalized collaboration with third parties and partner communities.

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• BIOVIA QUMAS EDMS: Electronic Document Management (EDM) applications with related R&D submission and QA documentation packages deliver proven regulatory compliance practices for document control and related training across the business. Based on customer and industry requirements and best practices, these BIOVIA QUMAS EDM applications eliminate the cost and complexity of managing paper-based as well as disparate or legacy process management applications.

• BIOVIA QUMAS Quality Management: By centralizing the management of all regulatory content and the associated change control processes, companies can consistently enforce standards across multiple locations. The BIOVIA QUMAS Quality Management Solution (QMS) manages a wide variety of processes including: audits, IT change control, event tracking and resolution, license and registrations tracking, CAPAs (corrective actions/preventive actions), quality checks, customer complaints and many others.

DELIVERING SCIENTIFIC INNOVATION IN THE AGE OF EXPERIENCEDassault Systèmes signed a definitive merger agreement to acquire Accelrys on January 30, 2014 with an all-cash tender offer for all of the outstanding shares of Accelrys common stock. The tender offer process was completed on April 29, 2014 with Accelrys filing the ‘Certification and Notice of Termination of Registration’ with the SEC on May 9, 2014.

Dassault Systèmes announced the creation of BIOVIA on May 21, 2014, describing the new company as a combination of Dassault Systèmes’ own activities in BioIntelligence, its collaborative 3DEXPERIENCE® technologies and the leading life sciences and material sciences applications resulting from the acquisition of Accelrys.

In today’s experience economy, the capability to develop, simulate and produce breakthrough experiences at the molecular level delivers transformational value for enterprises of all industries. BIOVIA is committed to enhancing and speeding innovation, improving productivity and compliance, reducing costs and accelerating product development from discovery through manufacturing.

Integrating BIOVIA’s strong suite of scientific informatics solutions with the Dassault Systèmes 3DEXPERIENCE® platform can create significant opportunities for BIOVIA to support and develop systemic collaboration, project management, data and content reuse, traceability and other processes, applications and integrations that are critical to science- and process-driven industries.

BIOVIA BACKGROUND AND HISTORYAccelrys was founded in 2001 from the combination of five companies and in 2004 acquired SciTegic, the developer of Pipeline Pilot data pipelining software, which has evolved into the BIOVIA Pipeline Pilot scientific workflow authoring application.

In July 2010, Accelrys merged with Symyx Technologies, Inc., combining Accelrys’ portfolio of scientific informatics solutions with the market-leading Symyx electronic laboratory notebook (ELN), now BIOVIA Workbook, and software products such as MDL Notebook, ISIS/Isentris, Available Chemicals Directory (ACD) and more. Subsequently, Accelrys extended its ELN capabilities through the acquisition of Contur Software AB in May 2011 and broadened its data capture and laboratory execution capabilities for the critical QA/QC phase of product development through the acquisition of VelQuest Corporation in January 2012. This was followed by the acquisition of Colorado-based Aegis Analytical Corporation in October 2012 with its Discoverant process knowledge and collaboration solution suite for compliance-intensive industries.

In January of 2013 Accelrys solidified its market leadership in the laboratory informatics space with the acquisition of Vialis AG, a leading informatics system integrator based in Liestal, Switzerland. The acquisition of ChemSW, Inc., an Environmental Health & Safety (EH&S) compliance solutions provider in September 2013 furthered Accelrys’ Scientific Product Lifecycle Management strategy by providing solutions for managing and tracking the source, use and disposal of chemicals along the entire lab-to-plant value chain. In December 2013 Accelrys acquired QUMAS, a Cork Ireland-based company focused on Enterprise Regulatory, Quality and Compliance Management.

This deliberate merger and acquisition strategy made Accelrys—now BIOVIA—one of the largest, most comprehensive scientific informatics providers in the world. Dassault Systèmes BIOVIA offers the experience, knowledge and know-how to design, develop and deploy successful enterprise-class solutions and experiences that can improve the productivity of science-driven innovators and accelerate new products to market.

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OFFICE LOCATIONSDassault Systèmes BIOVIA global headquarters is located in San Diego CA. The company currently employs approximately 750 people in software development, quality assurance, customer support, consulting, sales, marketing, accounting, finance and legal.

Dassault Systèmes, BIOVIA Corp.5005 Wateridge Vista Drive, San Diego, CA 92121, USA Tel: +1 858-799-5000 Fax: +1 858-799-5100

European HeadquartersDassault Systèmes, BIOVIA Ltd.: 334 Cambridge Science Park, Cambridge CB4 0WN Registered in England: 326316 Tel: +44 1223 228500 Fax: +44 1223 228501

Asia HeadquartersDassault Systèmes, BIOVIA K.K. ThinkPark Tower 2-1-1 Osaki, Shinagawa-ku, Tokyo 141-6020. Japan Tel:+81-3-4321-3900 Fax:+81-3-4321-3901

Bangalore, IndiaDassault Systèmes India Private Limited, The Leela Galleria, Commercial Block, 7th Floor, No. 23, Old Airport Road, Bangalore-560008, India. Telephone: +91 80 43 06 7000 Fax : +91 80 41502353

Basel, SwitzerlandInnere Margarethenstrasse 5 4051 Basel Switzerland Tel: +41 61 588 0395

Bedminster, New Jersey, USA135 US Highway 202/206, 1 FL Bedminster, NJ 07921 Tel: +1 908-947-2701 Fax: +1 908-947-2700

Bend, Oregon, USA755 SW Bonnett Way, Suite 2100 Bend, OR 97702 Tel: +1 541-312-8005 Fax: +1 541-318-8904

Boulder, Colorado, USA1380 Forest Park Circle Suite 200 Lafayette, CO 80026 USA Tel: +1 303 625 2100 Fax: +1 303 926 1161

Boston, USA200 Wheeler Road South Tower, 2nd Floor Burlington, MA 01803-5501, USA Tel: +1 781-229-9800 Fax: +1 781-229-9899

Durham, North Carolina, USA2511 Old Cornwallis Rd., Ste 280 Durham, NC 27713 Tel: +1 858-799-5000

Milford, Massachusetts, USA#9 Industrial Rd. Suite 4 Milford, MA 01757 Tel: +1 508-497-9911

Paris, FranceParc Club Orsay Université 20, Rue Jean Rostand, 91898 Orsay Cedex France Tel: +33 1 82 88 55 03 Fax: +33 1 72 70 35 30

Pleasanton, California, USA6700 Koll Center Parkway, Suite 225 Pleasanton, CA 94566 Tel: +1 858-799-5000 Fax: +1 858-799-5100

Seoul, Korea694-1 Sampyeong-dong, Korea BioPark Bldg C-602, Bundang-gu, Seongnam-si, Gyeonggi-do, 463-400, Korea Tel: +82 31-628-0321 Fax: +82 31-628-0333

Singapore80 Robinson Rd. #02-00 Singapore 068898

Stockholm, SwedenBirger Jarlsgatan 33, 2 tr 111 45 Stockholm Sweden Tel: +44 1223 228 500 Fax: +46 8663 70 05

Cork, IrelandCleve Business Park Monahan Road, Cork Ireland Tel: +353 21 491 5100 Fax: +353 21 432 0394

Cologne, GermanyHohenzollernring 84 D-50672 Cologne Germany

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Our 3DEXPERIENCE® platform powers our brand applications, serving 12 industries, and provides a rich portfolio of industry solution experiences. Dassault Systèmes, the 3DEXPERIENCE® Company, provides business and people with virtual universes to imagine sustainable innovations. Its world-leading solutions transform the way products are designed, produced, and supported. Dassault Systèmes’ collaborative solutions foster social innovation, expanding possibilities for the virtual world to improve the real world. The group brings value to over 190,000 customers of all sizes in all industries in more than 140 countries. For more information, visit www.3ds.com.

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Dassault Systèmes CorporateDassault Systèmes175 Wyman StreetWaltham, Massachusetts02451-1223USA

BIOVIA Corporate EuropeBIOVIA 334 Cambridge Science Park,Cambridge CB4 0WNEngland

BIOVIA Corporate AmericasBIOVIA 5005 Wateridge Vista Drive,San Diego, CA 92121USA

DS-9754-0317