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DISCLAIMER: This pathway is a resource that provides an overview of the presentation and clinical work-up of a cancer diagnosis that an individual in the Ontario cancer system may receive. The pathway is intended to be used for informational purposes only. The pathway is not intended to constitute or be a substitute for medical advice and should not be relied upon in any such regard. Further, all pathways are subject to clinical judgment and actual practice patterns may not follow the proposed steps set out in the pathway. In the situation where the reader is not a healthcare provider, the reader should always consult a healthcare provider if he/she has any questions regarding the information set out in the pathway. The information in the pathway does not create a physician-patient relationship between Cancer Care Ontario (CCO) and the reader. While care has been taken in the preparation of the information contained in the pathway, such information is provided on an as-isbasis, without any representation, warranty, or condition, whether express, or implied, statutory or otherwise, as to the informations quality, accuracy, currency, completeness, or reliability. CCO and the pathways content providers (including the physicians who contributed to the information in the pathway) shall have no liability, whether direct, indirect, consequential, contingent, special, or incidental, related to or arising from the information in the pathway or its use thereof, whether based on breach of contract or tort (including negligence), and even if advised of the possibility thereof. Anyone using the information in the pathway does so at his or her own risk, and by using such information, agrees to indemnify CCO and its content providers from any and all liability, loss, damages, costs and expenses (including legal fees and expenses) arising from such persons use of the information in the pathway. This pathway may not reflect all the available scientific research and is not intended as an exhaustive resource. CCO and its content providers assume no responsibility for omissions or incomplete information in this pathway. It is possible that other relevant scientific findings may have been reported since completion of this pathway. This pathway may be superseded by an updated pathway on the same topic. Cancer Care Ontario Breast Cancer Pathway Map 03.18 Printer Friendly Version Note: print 11x17 landscape for best results, some features and content are only available on web version of pathway map Follow-Up Treatment Diagnosis Screening Prevention Risk Assessment & Prevention Guidance (Page 2) Screening Risk Assessment (Page 3) » Average Risk Screening (Page 4) » High Risk Screening (Page 5) Assessment of Symptomatic Individuals (Page 6-7) Diagnostic Procedures (Page 8-9) Ductal Carcinoma In Situ (Page 10-11)) Invasive Breast Cancer (Page 12-17) Distant Metastases (Page 18) Local and/or Regional Recurrence (Page 19-20) Survivorship (Page 21-22) End of Life Care (Page 23)

Breast Cancer Pathway Map - cancercareontario.ca · DISCLAIMER: This pathway is a resource that provides an overview of the presentation and clinical work-up of a cancer diagnosis

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  • DISCLAIMER: This pathway is a resource that provides an overview of the presentation and clinical work-up of a cancer diagnosis that an individual in the Ontario cancer system may receive. The pathway is intended to be used for informational purposes only. The pathway is not intended to constitute or be a substitute for medical advice and should not be relied upon in any such regard. Further, all pathways are subject to clinical judgment and actual practice patterns may not follow the proposed steps set out in the pathway. In the situation where the reader is not a healthcare provider, the reader should always consult a healthcare provider if he/she has any questions regarding the information set out in the pathway. The information in the pathway does not create a physician-patient relationship between Cancer Care Ontario (CCO) and the reader. While care has been taken in the preparation of the information contained in the pathway, such information is provided on an as-is basis, without any representation, warranty, or condition, whether express, or implied, statutory or otherwise, as to the informations quality, accuracy, currency, completeness, or reliability. CCO and the pathways content providers (including the physicians who contributed to the information in the pathway) shall have no liability, whether direct, indirect, consequential, contingent, special, or incidental, related to or arising from the information in the pathway or its use thereof, whether based on breach of contract or tort (including negligence), and even if advised of the possibility thereof. Anyone using the information in the pathway does so at his or her own risk, and by using such information, agrees to indemnify CCO and its content providers from any and all liability, loss, damages, costs and expenses (including legal fees and expenses) arising from such persons use of the information in the pathway. This pathway may not reflect all the available scientific research and is not intended as an exhaustive resource. CCO and its content providers assume no responsibility for omissions or incomplete information in this pathway. It is possible that other relevant scientific findings may have been reported since completion of this pathway. This pathway may be superseded by an updated pathway on the same topic.

    Cancer Care Ontario

    Breast Cancer Pathway Map

    03.18 Printer Friendly Version

    Note: print 11x17 landscape for best results, some features and content are only available on web version of pathway map

    Follow-UpTreatmentDiagnosisScreeningPrevention

    Risk Assessment & Prevention

    Guidance

    (Page 2)

    Screening Risk Assessment

    (Page 3)

    Average Risk Screening

    (Page 4)

    High Risk Screening

    (Page 5)

    Assessment of Symptomatic

    Individuals

    (Page 6-7)

    Diagnostic Procedures

    (Page 8-9)

    Ductal Carcinoma In Situ

    (Page 10-11))

    Invasive Breast Cancer

    (Page 12-17)

    Distant Metastases

    (Page 18)

    Local and/or Regional

    Recurrence

    (Page 19-20)

    Survivorship

    (Page 21-22)

    End of Life Care

    (Page 23)

  • Risk A

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    Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance

    Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance

    DECISION POINT

    Discuss appropr iatebreast screening andOBSP average r iskeligibility

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-22

    CHARACTERISTIC A

    Connected to Screening | INT-124

    Eligible

    CHARACTERISTIC B

    Not eligibleFOLLOW-UP

    Follow-up managedby Pr imary CareProvider

    PRIMARY CARE FOL-3

    DECISION POINT

    Discuss appropr iatebreast screening andreassess High RiskOBSP eligibility

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-23

    CHARACTERISTIC A

    Connected to Screening | DEC-18

    Eligible

    CHARACTERISTIC B

    Not eligible (i.e. age, bilateralmastectomy)

    INTERVENTION

    ChemopreventionConsidered if age 35 years;assessment forappropriateness using Gail riskscore or other risk assessmentmodel

    MULTIPLE/UNSPECIFIEDSPECIALTY INT-109

    Resources / Tools

    U.S. Preventive Services TaskForce (USPSTF)recommendation on the use ofmedications for breast cancerrisk reduction.

    INTERVENTION

    Assessment of breastcancer r isk by familyphysician or otherhealthcare provider,or tool (i.e. My CancerIQ)Lifetime risk of breast cancershould be based on familyhistory and must be assessedusing IBIS or BOADICEAlifetime risk assessment tools.IBIS 10 year and BOADICEA 5year risk assessment tools

    MULTIPLE/UNSPECIFIEDSPECIALTY INT-110

    Resources / Tools

    My Cancer IQ

    IBIS risk assessment

    BOADICEA risk assessment

    Hide

    INTERVENTION

    Refer to GeneticsProgram for formalassessment ofhereditary breastcancer r isk andgenetic test wheneligible

    GENETICS INT-111

    CONSULTATION

    Refer ral toappropr iateHealthcare ProviderI.e. medical oncologist,surgeon, gynecologist,primary care provider

    MULTIPLE/UNSPECIFIEDSPECIALTY CON-44

    CHARACTERISTIC

    From High Risk OBSPScreening Program

    MULTIPLE/UNSPECIFIEDSPECIALTY CHA-12

    CONSULTATION

    Refer ral toappropr iateHealthcare ProviderI.e. medical oncologist,surgeon, gynecologist,primary care provider

    MULTIPLE/UNSPECIFIEDSPECIALTY CON-45

    DECISION POINT

    Assessment outcome

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-24

    CHARACTERISTIC A

    Connected to Screening | DEC-27

    Potentially eligible for HighRisk OBSP program

    Refer for assessment via OBSPRequisition for High Risk Screening

    CHARACTERISTIC B

    Eligible for geneticassessment but not eligiblethrough High Risk OBSPprogram (e.g. strong familyhistory & 18 to 29 years ofage)

    CHARACTERISTIC C

    Average lifetime risk of breastcancer

    Lifetime risk of breast cancershould be based on family historyand must have been assessedusing IBIS or BOADICEA lifetime

    CHARACTERISTIC D

    Increased risk of breast cancerfor non-genetic reasons (i.e.high risk lifestyle, alcohol,smoking, obesity, age)

    Resources / Tools

    OBSP Requisition for High RiskScreening

    Show all

    DECISION POINT

    Results of geneticassessment(s)

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-25

    CHARACTERISTIC A

    Carrier of pathogenic variant inBRCA 1/2

    CHARACTERISTIC B

    25% lifetime risk of breastcancer or carrier of pathogenicvariant in other penetrantgenes (e.g. TP53, CDH1,PTEN, STK11, CHEK2,

    Lifetime risk of breast cancershould be based on family historyand must have been assessedusing IBIS or BOADICEA lifetime

    CHARACTERISTIC C

  • Screening Risk A

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    Screening Risk Assessment Screening Risk Assessment Screening Risk Assessment Screening Risk Assessment Screening Risk Assessment Screening Risk Assessment Screening Risk Assessment Screening Risk Assessment Screening Risk Assessment Screening Risk Assessment Screening Risk Assessment

    Screening Risk Assessment Screening Risk Assessment Screening Risk Assessment Screening Risk Assessment Screening Risk Assessment Screening Risk Assessment Screening Risk Assessment Screening Risk Assessment Screening Risk Assessment Screening Risk Assessment Screening Risk Assessment

    Jump

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    INTERVENTION

    Formal assessment ofher editary br eastcancer risk

    GENETICS INT-117

    Resour ces / Tools

    OBSP Breast Cancer GeneticAssessment and/or T est Results

    DECISION POINT

    Genetic TestingEligibility

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-26

    CHARACTERISTIC A

    Eligible

    CHARACTERISTIC B

    Not eligible or patient declinestesting

    CONSULTATION

    Referral to OBSP forbr east cancer geneticassessment todetermine eligibilityfor High Risk OBSPNurse practitioners can assesspatient risk and complete theOBSP requisition for high risk

    GENETICS CON-47

    Resour ces / Tools

    OBSP Requisition for High RiskScreening

    INTERVENTION

    Patient declinesgenetic r eferral

    MULTIPLE/UNSPECIFIEDSPECIALTY INT-118

    DECISION POINT

    Clinical pr esentation

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-27

    CHARACTERISTIC A

    Asymptomatic

    CHARACTERISTIC B

    Connected to Diagnosis | CHA-14

    Symptomatic or a finding onclinical exam

    CONSULTATION

    Visit to Healthcar ePr oviderAverage Risk patients do notrequire a physician referral forthe OBSP

    MULTIPLE/UNSPECIFIEDSPECIALTY CON-48

    CONSULTATION

    Patient self-r efers toOBSP

    MULTIPLE/UNSPECIFIEDSPECIALTY CON-50

    Resour ces / Tools

    OBSP Screening Locations

    DECISION POINT

    Eligibility and riskassessment todetermineappr opriate scr eeninge.g. family and clinicalhistoryNurse practitioners can assesspatient risk and complete the

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-28

    CHARACTERISTIC A

    Connected to Screening | INT-124

    Average Risk

    Women are considered eligible foraverage risk screening if they areasymptomatic and meet all of thefollowing:1) Are 50-74 years ofage*;2) Have no personal historyof breast cancer;3) Have not had ascreening mammogram within last11 months;4) No current breastimplants

    *Women over age 74 canbe screened with the OBSP;however, they are encouraged to

    CHARACTERISTIC B

    Possible High Risk (Geneticassessment required todetermine High Risk OBSPeligibility)

    Women may be eligible for highrisk screening if they areasymptomatic, are 30-69 years of

    CHARACTERISTIC C

    Known High Risk (Eligible fordirect entry into High RiskOBSP)

    Women may be eligible for highrisk screening if they areasymptomatic, are 30-69 years of

    CHARACTERISTIC D

    Not eligble for OBSP (e.g. 74 years of age)*

    *Women over age 74 can bescreened with the OBSP; however,they are encourage to make a

    Resour ces / Tools

    CCO Cancer Screening forBreast Cancer

    OBSP Requisition for High RiskScreening

    Hide

    INTERVENTION

    Health car e pr oviderdiscusses riskappr opriate scr eeningand discusses healthbehaviourinterventions toreduce br east cancerrisk as appr opriate(e.g. exercise, nutrition)

    There is insufficient evidenceto recommend appropriatescreening guidelines for somerisk categories (e.g. a 40 yearold woman at increased butnot high risk). Risk appropriatescreening in these cases is apersonalized decision madebetween the woman and herhealthcare provider.

    PRIMARY CARE INT-119

    Guidelines

    EBS #23-1 - Healthy Eating,Physical Activity , and HealthyWeights Guideline for PublicHealth in Ontario

    DECISION POINT

    Reevaluate patientrisk

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-29

    CHARACTERISTIC A

    Connected to Screening | DEC-18

    Connected to Prevention | CHA-12

    25% lifetime risk of breastcancer

    Lifetime risk of breast cancershould be based on family historyand must have been assessedusing IBIS or BOADICEA lifetime

    CHARACTERISTIC B

    < 25% lifetime risk of breastcancer

    Lifetime risk of breast cancershould be based on family historyand must have been assessedusing IBIS or BOADICEA lifetime

    Resour ces / Tools

    IBIS risk assessment

    BOADICEA risk assessment

    Hide

    INTERVENTION

    Genetic Test

    GENETICS INT-120

    Resour ces / Tools

    OBSP Breast Cancer GeneticAssessment and/or T est Results

    DECISION POINT

    Results

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-30

    CHARACTERISTIC A

    Connected to Screening | DEC-18

    Connected to Prevention | CHA-12

    Carrier of pathogenic variant inBRCA 1/2 or carrier of otherhigh penetrant gene (e.g.TP53, CDH1, PTEN, STK11)

    CHARACTERISTIC B

    True negative result for knownhereditary gene mutation infamily

    CHARACTERISTIC C

    No deleterious mutationidentified or variant ofundetermined significance

    INTERVENTION

    Health car e pr oviderdiscusses riskappr opriate scr eeningand discusses healthbehaviourinterventions toreduce br east cancerrisk as appr opriate(e.g. exercise, nutrition)

    There is insufficient evidenceto recommend appropriate

    PRIMARY CARE INT-121

    Guidelines

    EBS #23-1 - Healthy Eating,Physical Activity , and HealthyWeights Guideline for PublicHealth in Ontario

    INTERVENTION

    Discuss scr eeningoptions withhealthcar e pr oviderwith r egards to thebenefits andlimitations ofscreening

    MULTIPLE/UNSPECIFIEDSPECIALTY INT-122

    INTERVENTION

    Return to riskappr opriate scr eening

    MULTIPLE/UNSPECIFIEDSPECIALTY INT-123

    CONSULTATION

    Referral to High RiskOBSPNurse practitioners can assesspatient risk and complete theOBSP requisition for high risk

    Connected to Screening | INT-83

    MULTIPLE/UNSPECIFIEDSPECIALTY CON-49

    Resour ces / Tools

    OBSP Requisition for High RiskScreening

    Decision Point

    Click to select between thefollowing options.

    Average RiskScreening

    High Risk Scr eening

    Average Risk Screening

    Average Risk Screening

    Average Risk Screening

    Average Risk Screening

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    Average Risk Screening Average Risk Screening Average Risk Screening Average Risk Screening Average Risk Screening Average Risk Screening Average Risk Screening Average Risk Screening Average Risk Screening

    Average Risk Screening Average Risk Screening Average Risk Screening Average Risk Screening Average Risk Screening Average Risk Screening Average Risk Screening Average Risk Screening Average Risk Screening

    INTERVENTION

    ScreeningmammogramEvery two years or annuallyas required for women ages50-74As outlined within the OBSP,annual mammograms may be

    RADIOLOGY INT-124

    Resour ces / Tools

    CCO Cancer ScreeningRecommendations

    DECISION POINT

    Results The management following theBI-RADS assessmentcategories are based on therecommendations from theAmerican College ofRadiology.

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-31

    CHARACTERISTIC A

    Normal (e.g. BI-RADS 1 or 2)

    CHARACTERISTIC B

    Abnormal (e.g. BI-RADS 0)

    Resour ces / Tools

    ACR BI-RADS Atlas

    DECISION POINT

    Results

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-32

    CHARACTERISTIC A

    Benign diagnostic assessment(e.g. normal tissue, simplecyst, minimally complicatedcyst)

    CHARACTERISTIC B

    Probably benign diagnosticassessment (e.g. BI-RADS 3)

    The management following theBI-RADS assessment categoriesare based on the recommendations

    CHARACTERISTIC C

    Connected to Diagnosis | DEC-39

    Abnormal diagnosticassessment

    Resour ces / Tools

    ACR BI-RADS Atlas

    DECISION POINT

    Results

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-33

    CHARACTERISTIC A

    Normal assessment

    Continuewith screening or diagnosticimaging follow-up

    CHARACTERISTIC B

    Connected to Diagnosis | DEC-39

    Abnormal assessment

    INTERVENTION

    Short-term imagingfollow-upRepeat imaging within 6months based on radiologist'srecommendations.

    RADIOLOGY INT-125

    FOLLOW-UP

    Continue scr eening

    MULTIPLE/UNSPECIFIEDSPECIALTY FOL-5

    INTERVENTION

    Diagnostic Assessment

    INTERVENTION

    DiagnosticMammogram

    AND/OR

    Ultrasound

    RADIOLOGY INT-126

    Assessm

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    atic IndividualsA

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    Assessment of Symptomatic Individuals Assessment of Symptomatic Individuals Assessment of Symptomatic Individuals Assessment of Symptomatic Individuals Assessment of Symptomatic Individuals Assessment of Symptomatic Individuals Assessment of Symptomatic Individuals

    Assessment of Symptomatic Individuals Assessment of Symptomatic Individuals Assessment of Symptomatic Individuals Assessment of Symptomatic Individuals Assessment of Symptomatic Individuals Assessment of Symptomatic Individuals Assessment of Symptomatic Individuals

    CHARACTERISTIC

    Patient pr esents withone or mor esymptoms of br eastcancer , such as:-Palpable mass-Concerningnipple discharge-New nippleretraction-Skin changes of thenipple or breast-Asymmetricthickening/nodularity

    MULTIPLE/UNSPECIFIEDSPECIALTY CHA-14

    DECISION POINT

    Patient's Age

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-34

    CHARACTERISTIC A

    40 years of age

    INTERVENTION

    Clinical r eassessmentof symptoms

    PRIMARY CARE INT-127

    INTERVENTION

    Healthcar e pr oviderdiscusses riskappr opriate scr eeningThere is insufficient evidenceto recommend appropriatescreening guidelines for somerisk categories (e.g. a 40 yearold woman at increased butnot high risk). Risk appropriatescreening in these cases is apersonalized decision madebetween the woman and herhealthcare provider.

    Connected to Screening | DEC-27

    PRIMARY CARE INT-128

    INTERVENTION

    Ultrasound

    RADIOLOGY INT-129

    DECISION POINT

    Imaging Results

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-35

    CHARACTERISTIC A

    Normal

    CHARACTERISTIC B

    Probably benign (BI-RADS 3)

    The management following theBI-RADS assessment categoriesare based on the recommendationsfrom the American College ofRadiology.

    CHARACTERISTIC C

    Connected to Diagnosis | DEC-39

    Suspicious

    Resour ces / Tools

    ACR BI-RADS Atlas

    DECISION POINT

    Results

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-36

    CHARACTERISTIC A

    Persistent suspicious findings

    CHARACTERISTIC B

    Normal assessment

    DECISION POINT

    Results

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-37

    CHARACTERISTIC A

    Normal assessment

    CHARACTERISTIC B

    Suspicious

    FOLLOW-UP

    INTERVENTION

    Short-term imagingfollow-upRepeat imaging within 6months based on radiologist'srecommendations.

    RADIOLOGY INT-130

    INTERVENTION

    Clinical r eassessmentof symptoms

    PRIMARY CARE INT-131INTERVENTION

    INTERVENTION

    Ultrasound

    RADIOLOGY INT-132

    INTERVENTION

    Mammogram

    RADIOLOGY INT-133

    INTERVENTION

    GalactographyIn appropriate clinical contexts

    RADIOLOGY INT-134

    INTERVENTION

    INTERVENTION

    Ultrasound

    RADIOLOGY INT-135

    INTERVENTION

    Mammogram

    RADIOLOGY INT-136

    INTERVENTION

    GalactographyIn appropriate clinical contexts

    RADIOLOGY INT-137

    Diagnostic Procedures

    Diagnostic Procedures

    Diagnostic Procedures

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    Diagnostic Procedures

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    Diagnostic Procedures Diagnostic Procedures Diagnostic Procedures Diagnostic Procedures Diagnostic Procedures Diagnostic Procedures Diagnostic Procedures Diagnostic Procedures Diagnostic Procedures Diagnostic Procedures Diagnostic Procedures Diagnostic Procedures Diagnostic Procedures Diagnostic Procedures Diagnostic Procedures Diagnostic Procedures Diagnostic Procedures

    Diagnostic Procedures Diagnostic Procedures Diagnostic Procedures Diagnostic Procedures Diagnostic Procedures Diagnostic Procedures Diagnostic Procedures Diagnostic Procedures Diagnostic Procedures Diagnostic Procedures Diagnostic Procedures Diagnostic Procedures Diagnostic Procedures Diagnostic Procedures Diagnostic Procedures Diagnostic Procedures Diagnostic Procedures

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    FOLLOW-UP

    Consider short-termimaging follow-up orreturn torisk-appr opriatescreening

    MULTIPLE/UNSPECIFIEDSPECIALTY FOL-6

    INTERVENTION

    Second cor e needlebiopsy or vacuumbiopsyIf discordant upon secondbiopsy, refer to surgeon.

    RADIOLOGY INT-138

    CONSULTATION

    Referral to Surgeon

    SURGICAL ONCOLOGY CON-51

    DECISION POINT

    Results

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-38

    CHARACTERISTIC A

    Benign

    CHARACTERISTIC B

    High risk/concerning benignlesions

    e.g. Atypical ductal hyperplasia,radial scars, papilloma

    CHARACTERISTIC C

    Cancer

    CHARACTERISTIC D

    Insufficient tissue sampling

    CONSULTATION

    Referral to Surgeon

    SURGICAL ONCOLOGY CON-52

    INTERVENTION

    Biopsy

    SURGICAL ONCOLOGY INT-139

    DECISION POINT

    Finding(s)

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-39

    CHARACTERISTIC A

    Suspicious mass onultrasound, complex cyst,intraductal nodule, concerningcalcifications, suspiciousmammographic finding

    An excisional biopsy may beconsidered for presumed isolatedpapillary lesions in the appropriateclinical context

    CHARACTERISTIC B

    Axillary lymph nodes:indeterminate or concerning

    CHARACTERISTIC C

    MRI suspicious lesion

    Only for high risk patients

    INTERVENTION

    Cor e biopsyVacuum assisted with clipplacement

    RADIOLOGY INT-140

    CONSULTATION

    Referral to Surgeon

    SURGICAL ONCOLOGY CON-53

    INTERVENTION

    Fine needle aspiration

    OR

    Cor e Biopsy

    RADIOLOGY INT-141

    DECISION POINT

    Concordance withpathology , imagingand clinicalexamination

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-40

    CHARACTERISTIC A

    Concordant

    CHARACTERISTIC B

    Discordant

    INTERVENTION

    PathologyE.g. ER, PgR, HER2Biomarkers should beperformed on core biopsiesshowing invasive cancer.

    PATHOLOGY INT-142

    Resour ces / Tools

    Summary Statement: 2013ASCO/CAP HER2 Guidelines:Building a Consensus forOntario

    Breast T issue Pathway Map

    Hide

    INTERVENTION

    Cor e biopsy

    RADIOLOGY INT-143

    DECISION POINT

    Type of cancer

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-41

    CHARACTERISTIC A

    Connected to Treatment | CON-57

    Ductal Carcinoma In Situ

    CHARACTERISTIC B

    Connected to Treatment | CON-7

    Invasive Breast Cancer

    INTERVENTION

    Healthcar e pr oviderdiscusses riskappr opriate scr eeningor short term imagingfollow-upThere is insufficient evidenceto recommend appropriatescreening guidelines for somerisk categories (e.g. a 40 yearold woman at increased butnot high risk). Risk appropriatescreening in these cases is apersonalized decision madebetween the woman and herhealthcare provider.

    Connected to Screening | DEC-27

    PRIMARY CARE INT-144

    DECISION POINT

    Type of cancer

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-42

    CHARACTERISTIC A

    Connected to Treatment | CON-57

    Ductal Carcinoma In Situ

    CHARACTERISTIC B

    Invasive Breast Cancer

    CONSULTATION

    Referral to Surgeon

    SURGICAL ONCOLOGY CON-54

    INTERVENTION

    Second cor e biopsy

    RADIOLOGY INT-145

    INTERVENTION

    Biomarker TestingE.g. ER, PgR, HER2If not already initiated

    Connected to Treatment | CON-7

    PATHOLOGY INT-146

    Resour ces / Tools

    Summary Statement: 2013ASCO/CAP HER2 Guidelines:Building a Consensus forOntario

    Breast T issue Pathway Map

    Hide

    DECISION POINT

    Results

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-43

    CHARACTERISTIC A

    Benign

    CHARACTERISTIC B

    Connected to Prevention | CHA-13

    Confirmed high risk benign

    CHARACTERISTIC C

    Cancer

    DECISION POINT

    Decision r egardingfurther diagnostictest(s) needed

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-44

    CHARACTERISTIC A

    Excisional biopsy or short-termimaging

    CHARACTERISTIC B

    Connected to Screening | DEC-27

    Risk appropriate screening

    INTERVENTION

    PathologyBiomarkers should beperformed on core biopsiesshowing invasive cancer.

    PATHOLOGY INT-147

    Resour ces / Tools

    Breast T issue Pathway Map

    INTERVENTION

    Choose one of the following:

    INTERVENTION

    Excisional biopsy

    SURGICAL ONCOLOGY INT-148

    FOLLOW-UP

    Short-term imagingfollow-upRepeat imaging within 6months based on radiologist'srecommendations.

    MULTIPLE/UNSPECIFIEDSPECIALTY FOL-7

    Decision Point

    Click to select between thefollowing options.

    Ductal Car cinoma InSitu

    Invasive Br eastCancer

    Distant Metastases

    Local and/orRegional Recurr ence

    Invasive Breast C

    ancerInvasive B

    reast Cancer

    Invasive Breast C

    ancerInvasive B

    reast Cancer

    Invasive Breast C

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    Invasive Breast C

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    Invasive Breast C

    ancerInvasive B

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    Invasive Breast C

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    Invasive Breast C

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    Invasive Breast C

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    Invasive Breast C

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    Invasive Breast C

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    Invasive Breast C

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    Invasive Breast C

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    Invasive Breast C

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    ancerInvasive B

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    Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer

    Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer Invasive Breast Cancer

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    DATA 4INTERVENTION

    Breast conservingsurgery and axillarylymph node dissection Consultation with plasticsurgeon may be appropriate insome cases

    SURGICAL ONCOLOGY INT-15

    Guidelines

    EBS #1-1 - SurgicalManagement of Early-StageInvasive Breast Cancer

    EBS #17-5 - Sentinel L ymphNode Biopsy in Early-StageBreast Cancer

    Hide

    CONSULTATION

    Radiation Oncologist

    RADIATION ONCOLOGY CON-6

    INTERVENTION

    Pathology If no cancer in surgicalspecimen (e.g. very smalltumours,

  • Risk A

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    Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance

    Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance

    DECISION POINT

    Discuss appropr iatebreast screening andOBSP average r iskeligibility

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-22

    CHARACTERISTIC A

    Connected to Screening | INT-124

    Eligible

    CHARACTERISTIC B

    Not eligibleFOLLOW-UP

    Follow-up managedby Pr imary CareProvider

    PRIMARY CARE FOL-3

    DECISION POINT

    Discuss appropr iatebreast screening andreassess High RiskOBSP eligibility

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-23

    CHARACTERISTIC A

    Connected to Screening | DEC-18

    Eligible

    CHARACTERISTIC B

    Not eligible (i.e. age, bilateralmastectomy)

    INTERVENTION

    ChemopreventionConsidered if age 35 years;assessment forappropriateness using Gail riskscore or other risk assessmentmodel

    MULTIPLE/UNSPECIFIEDSPECIALTY INT-109

    Resources / Tools

    U.S. Preventive Services TaskForce (USPSTF)recommendation on the use ofmedications for breast cancerrisk reduction.

    INTERVENTION

    Assessment of breastcancer r isk by familyphysician or otherhealthcare provider,or tool (i.e. My CancerIQ)Lifetime risk of breast cancershould be based on familyhistory and must be assessedusing IBIS or BOADICEAlifetime risk assessment tools.IBIS 10 year and BOADICEA 5year risk assessment tools

    MULTIPLE/UNSPECIFIEDSPECIALTY INT-110

    Resources / Tools

    My Cancer IQ

    IBIS risk assessment

    BOADICEA risk assessment

    Hide

    INTERVENTION

    Refer to GeneticsProgram for formalassessment ofhereditary breastcancer r isk andgenetic test wheneligible

    GENETICS INT-111

    CONSULTATION

    Refer ral toappropr iateHealthcare ProviderI.e. medical oncologist,surgeon, gynecologist,primary care provider

    MULTIPLE/UNSPECIFIEDSPECIALTY CON-44

    CHARACTERISTIC

    From High Risk OBSPScreening Program

    MULTIPLE/UNSPECIFIEDSPECIALTY CHA-12

    CONSULTATION

    Refer ral toappropr iateHealthcare ProviderI.e. medical oncologist,surgeon, gynecologist,primary care provider

    MULTIPLE/UNSPECIFIEDSPECIALTY CON-45

    DECISION POINT

    Assessment outcome

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-24

    CHARACTERISTIC A

    Connected to Screening | DEC-27

    Potentially eligible for HighRisk OBSP program

    Refer for assessment via OBSPRequisition for High Risk Screening

    CHARACTERISTIC B

    Eligible for geneticassessment but not eligiblethrough High Risk OBSPprogram (e.g. strong familyhistory & 18 to 29 years ofage)

    CHARACTERISTIC C

    Average lifetime risk of breastcancer

    Lifetime risk of breast cancershould be based on family historyand must have been assessedusing IBIS or BOADICEA lifetime

    CHARACTERISTIC D

    Increased risk of breast cancerfor non-genetic reasons (i.e.high risk lifestyle, alcohol,smoking, obesity, age)

    Resources / Tools

    OBSP Requisition for High RiskScreening

    Show all

    DECISION POINT

    Results of geneticassessment(s)

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-25

    CHARACTERISTIC A

    Carrier of pathogenic variant inBRCA 1/2

    CHARACTERISTIC B

    25% lifetime risk of breastcancer or carrier of pathogenicvariant in other penetrantgenes (e.g. TP53, CDH1,PTEN, STK11, CHEK2,

    Lifetime risk of breast cancershould be based on family historyand must have been assessedusing IBIS or BOADICEA lifetime

    CHARACTERISTIC C

  • Risk A

    ssessment &

    Prevention Guidance

    Risk A

    ssessment &

    Prevention Guidance

    Risk A

    ssessment &

    Prevention Guidance

    Risk A

    ssessment &

    Prevention Guidance

    Risk A

    ssessment &

    Prevention Guidance

    Risk A

    ssessment &

    Prevention Guidance

    Risk A

    ssessment &

    Prevention Guidance

    Risk A

    ssessment &

    Prevention Guidance

    Risk A

    ssessment &

    Prevention Guidance

    Risk A

    ssessment &

    Prevention Guidance

    Risk A

    ssessment &

    Prevention Guidance

    Risk A

    ssessment &

    Prevention Guidance

    Risk A

    ssessment &

    Prevention Guidance

    Risk A

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    Prevention Guidance

    Risk A

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    Risk A

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    Prevention Guidance

    Risk A

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    Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance

    Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance

    DECISION POINT

    Discuss appr opriatebr east scr eening andOBSP average riskeligibility

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-22

    CHARACTERISTIC A

    Connected to Screening | INT-124

    Eligible

    CHARACTERISTIC B

    Not eligibleFOLLOW-UP

    Follow-up managedby Primary Car ePr ovider

    PRIMARY CARE FOL-3

    DECISION POINT

    Discuss appr opriatebr east scr eening andreassess High RiskOBSP eligibility

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-23

    CHARACTERISTIC A

    Connected to Screening | DEC-18

    Eligible

    CHARACTERISTIC B

    Not eligible (i.e. age, bilateralmastectomy)

    INTERVENTION

    Chemopr eventionConsidered if age 35 years;assessment forappropriateness using Gail riskscore or other risk assessmentmodel

    MULTIPLE/UNSPECIFIEDSPECIALTY INT-109

    Resources / Tools

    U.S. Preventive Services TaskForce (USPSTF)recommendation on the use ofmedications for breast cancerrisk reduction.

    INTERVENTION

    Assessment of br eastcancer risk by familyphysician or otherhealthcar e pr ovider,or tool (i.e. My CancerIQ)Lifetime risk of breast cancershould be based on familyhistory and must be assessedusing IBIS or BOADICEAlifetime risk assessment tools.IBIS 10 year and BOADICEA 5year risk assessment tools

    MULTIPLE/UNSPECIFIEDSPECIALTY INT-110

    Resources / Tools

    My Cancer IQ

    IBIS risk assessment

    BOADICEA risk assessment

    Hide

    INTERVENTION

    Refer to GeneticsPr ogram for formalassessment ofher editary br eastcancer risk andgenetic test wheneligible

    GENETICS INT-111

    CONSULTATION

    Referral toappr opriateHealthcar e Pr oviderI.e. medical oncologist,surgeon, gynecologist,primary care provider

    MULTIPLE/UNSPECIFIEDSPECIALTY CON-44

    CHARACTERISTIC

    Fr om High Risk OBSPScreening Pr ogram

    MULTIPLE/UNSPECIFIEDSPECIALTY CHA-12

    CONSULTATION

    Referral toappr opriateHealthcar e Pr oviderI.e. medical oncologist,surgeon, gynecologist,primary care provider

    MULTIPLE/UNSPECIFIEDSPECIALTY CON-45

    DECISION POINT

    Assessment outcome

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-24

    CHARACTERISTIC A

    Connected to Screening | DEC-27

    Potentially eligible for HighRisk OBSP program

    Refer for assessment via OBSPRequisition for High Risk Screening

    CHARACTERISTIC B

    Eligible for geneticassessment but not eligiblethrough High Risk OBSPprogram (e.g. strong familyhistory & 18 to 29 years ofage)

    CHARACTERISTIC C

    Average lifetime risk of breastcancer

    Lifetime risk of breast cancershould be based on family historyand must have been assessedusing IBIS or BOADICEA lifetime

    CHARACTERISTIC D

    Increased risk of breast cancerfor non-genetic reasons (i.e.high risk lifestyle, alcohol,smoking, obesity, age)

    Resources / Tools

    OBSP Requisition for High RiskScreening

    Show all

    DECISION POINT

    Results of geneticassessment(s)

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-25

    CHARACTERISTIC A

    Carrier of pathogenic variant inBRCA 1/2

    CHARACTERISTIC B

    25% lifetime risk of breastcancer or carrier of pathogenicvariant in other penetrantgenes (e.g. TP53, CDH1,PTEN, STK11, CHEK2,

    Lifetime risk of breast cancershould be based on family historyand must have been assessedusing IBIS or BOADICEA lifetime

    CHARACTERISTIC C

  • Risk A

    ssessment &

    Prevention Guidance

    Risk A

    ssessment &

    Prevention Guidance

    Risk A

    ssessment &

    Prevention Guidance

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    ssessment &

    Prevention Guidance

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    ssessment &

    Prevention Guidance

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    ssessment &

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    ssessment &

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    Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance

    Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance

    DECISION POINT

    Discuss appropr iatebreast screening andOBSP average r iskeligibility

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-22

    CHARACTERISTIC A

    Connected to Screening | INT-124

    Eligible

    CHARACTERISTIC B

    Not eligibleFOLLOW-UP

    Follow-up managedby Pr imary CareProvider

    PRIMARY CARE FOL-3

    DECISION POINT

    Discuss appropr iatebreast screening andreassess High RiskOBSP eligibility

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-23

    CHARACTERISTIC A

    Connected to Screening | DEC-18

    Eligible

    CHARACTERISTIC B

    Not eligible (i.e. age, bilateralmastectomy)

    INTERVENTION

    ChemopreventionConsidered if age 35 years;assessment forappropriateness using Gail riskscore or other risk assessmentmodel

    MULTIPLE/UNSPECIFIEDSPECIALTY INT-109

    Resources / Tools

    U.S. Preventive Services TaskForce (USPSTF)recommendation on the use ofmedications for breast cancerrisk reduction.

    INTERVENTION

    Assessment of breastcancer r isk by familyphysician or otherhealthcare provider,or tool (i.e. My CancerIQ)Lifetime risk of breast cancershould be based on familyhistory and must be assessedusing IBIS or BOADICEAlifetime risk assessment tools.IBIS 10 year and BOADICEA 5year risk assessment tools

    MULTIPLE/UNSPECIFIEDSPECIALTY INT-110

    Resources / Tools

    My Cancer IQ

    IBIS risk assessment

    BOADICEA risk assessment

    Hide

    INTERVENTION

    Refer to GeneticsProgram for formalassessment ofhereditary breastcancer r isk andgenetic test wheneligible

    GENETICS INT-111

    CONSULTATION

    Refer ral toappropr iateHealthcare ProviderI.e. medical oncologist,surgeon, gynecologist,primary care provider

    MULTIPLE/UNSPECIFIEDSPECIALTY CON-44

    CHARACTERISTIC

    From High Risk OBSPScreening Program

    MULTIPLE/UNSPECIFIEDSPECIALTY CHA-12

    CONSULTATION

    Refer ral toappropr iateHealthcare ProviderI.e. medical oncologist,surgeon, gynecologist,primary care provider

    MULTIPLE/UNSPECIFIEDSPECIALTY CON-45

    DECISION POINT

    Assessment outcome

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-24

    CHARACTERISTIC A

    Connected to Screening | DEC-27

    Potentially eligible for HighRisk OBSP program

    Refer for assessment via OBSPRequisition for High Risk Screening

    CHARACTERISTIC B

    Eligible for geneticassessment but not eligiblethrough High Risk OBSPprogram (e.g. strong familyhistory & 18 to 29 years ofage)

    CHARACTERISTIC C

    Average lifetime risk of breastcancer

    Lifetime risk of breast cancershould be based on family historyand must have been assessedusing IBIS or BOADICEA lifetime

    CHARACTERISTIC D

    Increased risk of breast cancerfor non-genetic reasons (i.e.high risk lifestyle, alcohol,smoking, obesity, age)

    Resources / Tools

    OBSP Requisition for High RiskScreening

    Show all

    DECISION POINT

    Results of geneticassessment(s)

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-25

    CHARACTERISTIC A

    Carrier of pathogenic variant inBRCA 1/2

    CHARACTERISTIC B

    25% lifetime risk of breastcancer or carrier of pathogenicvariant in other penetrantgenes (e.g. TP53, CDH1,PTEN, STK11, CHEK2,

    Lifetime risk of breast cancershould be based on family historyand must have been assessedusing IBIS or BOADICEA lifetime

    CHARACTERISTIC C

  • Risk A

    ssessment &

    Prevention Guidance

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    Prevention Guidance

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    Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance

    Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance

    DECISION POINT

    Discuss appropr iatebreast screening andOBSP average r iskeligibility

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-22

    CHARACTERISTIC A

    Connected to Screening | INT-124

    Eligible

    CHARACTERISTIC B

    Not eligibleFOLLOW-UP

    Follow-up managedby Pr imary CareProvider

    PRIMARY CARE FOL-3

    DECISION POINT

    Discuss appropr iatebreast screening andreassess High RiskOBSP eligibility

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-23

    CHARACTERISTIC A

    Connected to Screening | DEC-18

    Eligible

    CHARACTERISTIC B

    Not eligible (i.e. age, bilateralmastectomy)

    INTERVENTION

    ChemopreventionConsidered if age 35 years;assessment forappropriateness using Gail riskscore or other risk assessmentmodel

    MULTIPLE/UNSPECIFIEDSPECIALTY INT-109

    Resources / Tools

    U.S. Preventive Services TaskForce (USPSTF)recommendation on the use ofmedications for breast cancerrisk reduction.

    INTERVENTION

    Assessment of breastcancer r isk by familyphysician or otherhealthcare provider,or tool (i.e. My CancerIQ)Lifetime risk of breast cancershould be based on familyhistory and must be assessedusing IBIS or BOADICEAlifetime risk assessment tools.IBIS 10 year and BOADICEA 5year risk assessment tools

    MULTIPLE/UNSPECIFIEDSPECIALTY INT-110

    Resources / Tools

    My Cancer IQ

    IBIS risk assessment

    BOADICEA risk assessment

    Hide

    INTERVENTION

    Refer to GeneticsProgram for formalassessment ofhereditary breastcancer r isk andgenetic test wheneligible

    GENETICS INT-111

    CONSULTATION

    Refer ral toappropr iateHealthcare ProviderI.e. medical oncologist,surgeon, gynecologist,primary care provider

    MULTIPLE/UNSPECIFIEDSPECIALTY CON-44

    CHARACTERISTIC

    From High Risk OBSPScreening Program

    MULTIPLE/UNSPECIFIEDSPECIALTY CHA-12

    CONSULTATION

    Refer ral toappropr iateHealthcare ProviderI.e. medical oncologist,surgeon, gynecologist,primary care provider

    MULTIPLE/UNSPECIFIEDSPECIALTY CON-45

    DECISION POINT

    Assessment outcome

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-24

    CHARACTERISTIC A

    Connected to Screening | DEC-27

    Potentially eligible for HighRisk OBSP program

    Refer for assessment via OBSPRequisition for High Risk Screening

    CHARACTERISTIC B

    Eligible for geneticassessment but not eligiblethrough High Risk OBSPprogram (e.g. strong familyhistory & 18 to 29 years ofage)

    CHARACTERISTIC C

    Average lifetime risk of breastcancer

    Lifetime risk of breast cancershould be based on family historyand must have been assessedusing IBIS or BOADICEA lifetime

    CHARACTERISTIC D

    Increased risk of breast cancerfor non-genetic reasons (i.e.high risk lifestyle, alcohol,smoking, obesity, age)

    Resources / Tools

    OBSP Requisition for High RiskScreening

    Show all

    DECISION POINT

    Results of geneticassessment(s)

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-25

    CHARACTERISTIC A

    Carrier of pathogenic variant inBRCA 1/2

    CHARACTERISTIC B

    25% lifetime risk of breastcancer or carrier of pathogenicvariant in other penetrantgenes (e.g. TP53, CDH1,PTEN, STK11, CHEK2,

    Lifetime risk of breast cancershould be based on family historyand must have been assessedusing IBIS or BOADICEA lifetime

    CHARACTERISTIC C

  • Risk A

    ssessment &

    Prevention Guidance

    Risk A

    ssessment &

    Prevention Guidance

    Risk A

    ssessment &

    Prevention Guidance

    Risk A

    ssessment &

    Prevention Guidance

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    ssessment &

    Prevention Guidance

    Risk A

    ssessment &

    Prevention Guidance

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    ssessment &

    Prevention Guidance

    Risk A

    ssessment &

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    Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance

    Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance

    DECISION POINT

    Discuss appropr iatebreast screening andOBSP average r iskeligibility

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-22

    CHARACTERISTIC A

    Connected to Screening | INT-124

    Eligible

    CHARACTERISTIC B

    Not eligibleFOLLOW-UP

    Follow-up managedby Pr imary CareProvider

    PRIMARY CARE FOL-3

    DECISION POINT

    Discuss appropr iatebreast screening andreassess High RiskOBSP eligibility

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-23

    CHARACTERISTIC A

    Connected to Screening | DEC-18

    Eligible

    CHARACTERISTIC B

    Not eligible (i.e. age, bilateralmastectomy)

    INTERVENTION

    ChemopreventionConsidered if age 35 years;assessment forappropriateness using Gail riskscore or other risk assessmentmodel

    MULTIPLE/UNSPECIFIEDSPECIALTY INT-109

    Resources / Tools

    U.S. Preventive Services TaskForce (USPSTF)recommendation on the use ofmedications for breast cancerrisk reduction.

    INTERVENTION

    Assessment of breastcancer r isk by familyphysician or otherhealthcare provider,or tool (i.e. My CancerIQ)Lifetime risk of breast cancershould be based on familyhistory and must be assessedusing IBIS or BOADICEAlifetime risk assessment tools.IBIS 10 year and BOADICEA 5year risk assessment tools

    MULTIPLE/UNSPECIFIEDSPECIALTY INT-110

    Resources / Tools

    My Cancer IQ

    IBIS risk assessment

    BOADICEA risk assessment

    Hide

    INTERVENTION

    Refer to GeneticsProgram for formalassessment ofhereditary breastcancer r isk andgenetic test wheneligible

    GENETICS INT-111

    CONSULTATION

    Refer ral toappropr iateHealthcare ProviderI.e. medical oncologist,surgeon, gynecologist,primary care provider

    MULTIPLE/UNSPECIFIEDSPECIALTY CON-44

    CHARACTERISTIC

    From High Risk OBSPScreening Program

    MULTIPLE/UNSPECIFIEDSPECIALTY CHA-12

    CONSULTATION

    Refer ral toappropr iateHealthcare ProviderI.e. medical oncologist,surgeon, gynecologist,primary care provider

    MULTIPLE/UNSPECIFIEDSPECIALTY CON-45

    DECISION POINT

    Assessment outcome

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-24

    CHARACTERISTIC A

    Connected to Screening | DEC-27

    Potentially eligible for HighRisk OBSP program

    Refer for assessment via OBSPRequisition for High Risk Screening

    CHARACTERISTIC B

    Eligible for geneticassessment but not eligiblethrough High Risk OBSPprogram (e.g. strong familyhistory & 18 to 29 years ofage)

    CHARACTERISTIC C

    Average lifetime risk of breastcancer

    Lifetime risk of breast cancershould be based on family historyand must have been assessedusing IBIS or BOADICEA lifetime

    CHARACTERISTIC D

    Increased risk of breast cancerfor non-genetic reasons (i.e.high risk lifestyle, alcohol,smoking, obesity, age)

    Resources / Tools

    OBSP Requisition for High RiskScreening

    Show all

    DECISION POINT

    Results of geneticassessment(s)

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-25

    CHARACTERISTIC A

    Carrier of pathogenic variant inBRCA 1/2

    CHARACTERISTIC B

    25% lifetime risk of breastcancer or carrier of pathogenicvariant in other penetrantgenes (e.g. TP53, CDH1,PTEN, STK11, CHEK2,

    Lifetime risk of breast cancershould be based on family historyand must have been assessedusing IBIS or BOADICEA lifetime

    CHARACTERISTIC C

  • Risk A

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    Risk A

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    Risk A

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    Prevention Guidance

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    Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance

    Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance Risk Assessment & Prevention Guidance

    DECISION POINT

    Discuss appropr iatebreast screening andOBSP average r iskeligibility

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-22

    CHARACTERISTIC A

    Connected to Screening | INT-124

    Eligible

    CHARACTERISTIC B

    Not eligibleFOLLOW-UP

    Follow-up managedby Pr imary CareProvider

    PRIMARY CARE FOL-3

    DECISION POINT

    Discuss appropr iatebreast screening andreassess High RiskOBSP eligibility

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-23

    CHARACTERISTIC A

    Connected to Screening | DEC-18

    Eligible

    CHARACTERISTIC B

    Not eligible (i.e. age, bilateralmastectomy)

    INTERVENTION

    ChemopreventionConsidered if age 35 years;assessment forappropriateness using Gail riskscore or other risk assessmentmodel

    MULTIPLE/UNSPECIFIEDSPECIALTY INT-109

    Resources / Tools

    U.S. Preventive Services TaskForce (USPSTF)recommendation on the use ofmedications for breast cancerrisk reduction.

    INTERVENTION

    Assessment of breastcancer r isk by familyphysician or otherhealthcare provider,or tool (i.e. My CancerIQ)Lifetime risk of breast cancershould be based on familyhistory and must be assessedusing IBIS or BOADICEAlifetime risk assessment tools.IBIS 10 year and BOADICEA 5year risk assessment tools

    MULTIPLE/UNSPECIFIEDSPECIALTY INT-110

    Resources / Tools

    My Cancer IQ

    IBIS risk assessment

    BOADICEA risk assessment

    Hide

    INTERVENTION

    Refer to GeneticsProgram for formalassessment ofhereditary breastcancer r isk andgenetic test wheneligible

    GENETICS INT-111

    CONSULTATION

    Refer ral toappropr iateHealthcare ProviderI.e. medical oncologist,surgeon, gynecologist,primary care provider

    MULTIPLE/UNSPECIFIEDSPECIALTY CON-44

    CHARACTERISTIC

    From High Risk OBSPScreening Program

    MULTIPLE/UNSPECIFIEDSPECIALTY CHA-12

    CONSULTATION

    Refer ral toappropr iateHealthcare ProviderI.e. medical oncologist,surgeon, gynecologist,primary care provider

    MULTIPLE/UNSPECIFIEDSPECIALTY CON-45

    DECISION POINT

    Assessment outcome

    MULTIPLE/UNSPECIFIEDSPECIALTY DEC-24

    CHARACTERISTIC A

    Connected to Screening | DEC-27

    Potentially eligible for HighRisk OBSP program

    Refer for assessment via OBSPRequisition for High Risk Screening

    CHARACTERISTIC B

    Eligible for geneticassessment but not eligiblethrough High Risk OBSPprogram (e.g. strong familyhistory & 18 to 29 years ofage)

    CHARACTERISTIC C

    Average lifetime risk of breastcancer

    Lifetime risk of breast cancershould be based on family historyand must have been assessedusing IBIS or BOADICEA lifetime

    CHARACTERISTIC D

    Increased risk of breast cancerfor non-genetic reasons (i.e.high risk lifestyle, alcohol,smoking, obesity, age)

    Resources / Tools

    OBSP Requisition for High RiskScreening

    Show all

    DECISION POINT

    Results of geneticassessment(s)

    MULTIPLE/UNSPECIF