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Cloning Neanderthal DNABringing a Species Out of ExtinctionBy, Rochelle Yantz
Background
The lonely Homo Sapien
Sapien…
tellsomeonetoday.blogspot.com
Background
George Church synthetic biologist and professor at Harvard Medical School
www.canada.com
Church’s Propositions & Reasoning“Technologies are developing faster than ever before… Reading and writing DNA is now about a million times faster than seven or eight
years ago” –George Church
Enlarged craniums could lead to different thought processes
Creates genetic diversity to decrease susceptibility to epidemics
Creates a more robust human species
www.ibri.org
Types of CloningType Definition History
DNA
Cloning/Recombinant
DNA Technology
Transfer of a DNA
fragment of interest
from one organism
to a self-replicating
genetic element (i.e.
bacterial plasmid)
Has been used since the 1970’s
Common practice in modern molecular biology
labs
Reproductive Cloning Generates an animal
that has identical
nuclear DNA as
another existing
animal
Used to create Dolly the sheep who lived for six
years
Therapeutic Cloning Production of human
embryos for use in
research (i.e. human
development and
treating diseases)
In 2001 a biotechnology company announced
they had produced the first human embryos
How to Bring Back a Neanderthal1. Sequence the Neanderthal genome2. Divide genome 10,000x to synthesize3. Introduce synthesized DNA to human stem cell4. Repeat (eventually the stem cell line will closely correlate a
Neanderthal’s5. Introduce DNA to surrogate mother
www.studyblue.com Neanderthal remains
Ethical BarriersLacking a sense of identityLiving under societal scrutinyViolating religious views on how humans are createdToo aggressive to interact with society “Frankenstein” Complex
herocomplex.latimes.com
Genetic Barriers
“Are we putting it together correctly?”- Ron Crystal, geneticist at Weill Cornell Medical College
Monogenic DisordersCystic FibrosisSickle Cell AnemiaFragile X SyndromeHuntington’s DiseaseEtc. http://www.rightdiagnosis.com/
medical/monogenic_disease.htm
www.mitochondrialdnatesting.com
What would you do if you came face-to-face with Homo Neanderthalensis?
http://www.youtube.com/watch?v=9NPWOMEmP-s
thebibleistheotherside.wordpress.com
Works Cited
Annear, Steve. "Harvard Professor Clears Up Comment About Cloning Neanderthals." BostInno. N.p., 22 Jan. 2013. Web. 11 Feb. 2013.Bethge, Philip, and Johann Grolle. "George Church Explains How DNA Will Be Construction Material of the Future." SPIEGEL ONLINE. N.p., 18 Jan. 2013. Web. 11 Feb. 2013.Bonsor, Kevin, and Cristen Conger. "How Human Cloning Will Work." HowStuffWorks. HowStuffWorks, Inc, n.d. Web. 28 Mar. 2013. http://science.howstuffworks.com/life/genetic/human-cloning1.htm"Cloning Fact Sheet." Cloning Fact Sheet. U.S. Department of Energy Office of Science, Office of Biological and Environmental Research, Human Genome Program, 11 May 2009. Web. 13 Apr. 2013. <http://www.ornl.gov/sci/techresources/Human_Genome/elsi/cloning.shtml>.Lupkin, Sydney. "Harvard Prof Says Neanderthal Clones Possible but Experts Doubt It." ABC News. ABC News Network, 22 Jan. 2013. Web. 28 Mar. 2013. <http://abcnews.go.com/Health/harvard-prof-neanderthal-clones-experts- doubt/story?id=18275611>.Pakhare, Jayashree. "Human Cloning Process." Buzzle.com. Buzzle.com, 12 Dec. 2011. Web. 28 Mar. 2013. <http://www.buzzle.com/articles/human-cloning-process.html>."Tour of the Basics: What Is DNA?" Tour of the Basics: What Is DNA? Genetic Science Learning Center, University of Utah, n.d. Web. 13 Apr. 2013. <http://learn.genetics.utah.edu/content/begin/dna/tour_dna.html>.
