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MRC Annual Report 2005 Presentation to the Portfolio Committee on Health Parliament, Cape Town October 24, 2005 Prof A D MBewu President, Medical Research Council. Building a healthy nation through research. Contents. Mandate of the MRC Ministry of Health National Department of Health - PowerPoint PPT Presentation
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Building a healthy nationthrough research
MRC Annual Report 2005MRC Annual Report 2005Presentation to the Portfolio Committee on HealthPresentation to the Portfolio Committee on Health
Parliament, Cape TownParliament, Cape Town
October 24, 2005October 24, 2005
Prof A D MBewuProf A D MBewuPresident,President,
Medical Research Council Medical Research Council
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ContentsContents
1. Mandate of the MRC2. Ministry of Health3. National Department of Health4. Research Translation5. MRC Mission and Strategic Objectives6. Transformation7. MRC Personnel8. A Knowledge creating company9. Inputs, Outputs and Outcomes
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Mandate of the MRCMandate of the MRC
MRC : Statutory Council Act 58 of 1969
MRC Mandate : from Act 58 of 1969
MRC Vision : ‘building a healthy nation through research’
MRC Mission : ‘to improve the nation’s health and quality of life through promoting and conducting relevant and responsive health research’
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Ministry of Health Ministry of Health
Government Line Department : NDOH
National System of Innovation : DST
Parliament : Portfolio Committee on Health
Minister of Health: Governance: Board and Chairperson of Board Research
President (CEO)
Research Priorities (National Health Research Council)MRC BusinessplanMRC Budget – to Treasury with NDOH Performance : KPIs and Quarterly ReportAnnual Report – Annual Financial Statements, etc
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National Department of HealthNational Department of Health
Research Priorities
MRC Budget R180 million – plus R180 million external income – total R350 million – reliably sustainable year after year (MTEF)Policy
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‘‘Research Translation’Research Translation’
GRIPP : Getting Research results Into PolicyPracticePromotion andProduct
Research makes no difference to health unless it is translatedMRC vision : ‘building a healthy nation through research’
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Policy
NDOH is the principal channel through which MRC research can improve the health of the nation develops national health policies to be tabled at Parliament and implements them with Provinces sets the norms and standards that guide preventive, health promotive, therapeutic and rehabilitative services for the people of South Africa
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Practice Practice
stakeholders such as healthcare professionals, social workers etc whose practice is influenced by what they read of MRC research.
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(Health) Promotion (Health) Promotion
• legislative and other instruments that create a healthy environment for South Africans;
• healthy choices that people can make to protect their health and wellbeing identifies the determinants underlying the behaviours that lead to such diseases determinants such as poverty, lack of education, or gender power imbalances;
• explores how the risk factors that arise from these behaviours and behaviours can result in disease – such as the undernutrition arising from poverty causing immune deficiency;
• develops and tests interventions that can alter risky behaviours – such as health education or peer modeling to reduce unprotected sex.
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Products Products
• patents for new drugs and vaccines, disclosures of new biomedical or public health processes
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Mission Mission
1.Research Strategy and Businessplan2.Financial Model Strategy & Plan 3.Opportunity and Risk Management4.Capacity building5.Informatics and Knowledge Management6.Transformation and Development Plan7.Research Translation8.Stakeholder Management
The MRC mission is implemented through the following Strategic Objectives:
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Transformation Transformation
•Organisational Culture and Values•Research priorities •Research portfolio•Capacity development •Employment equity profile
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Transformation Transformation
•Organisational Culture and Values•Research priorities •Research portfolio•Capacity development •Employment equity profile
Occupational Level BlackApril 2005
FemaleApril 2005
Top Management 86 % 33 %
Senior Management 23 % 44 %
Middle Management 50 % 59 %
Skilled 78 % 75 %
Semi-Skilled 85 % 66 %
Unskilled 98 % 42 %
Total 74 % 66 %
In the next 3 – 5 years the MRC expects more black and women scientists to be brought into the research process at the doctoral and postdoctoral level.
The opportunity now exists to complete that transformation over the next three years resulting in an MRC that conducts research, relevant and responsive to the health needs of the people of South Africa; and whose personnel fully reflects the demographic profile of South Africa.
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MRC Personnel MRC Personnel
The MRC is a ‘Knowledge creating company’ and people are therefore its most important resource:
PERSONNEL250 Research Scientists in 21 units250 Technologists250 Support staff250 Research scientists in 27 units (800 intramural personnel)200 Technologists200 S I R150 PhD students ~ 1200 extramural150 M students ~ 2000 employed by or associated with MRC250 SAAVI
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A Knowledge Creating Company A Knowledge Creating Company
KNOWLEDGE-CREATING COMPANY
INPUTSPERSONNEL
SYSTEMS INFRASTRUCTURE
OUTPUTS~publications~ patents~ technical reports~ post graduates
OUTCOMES health presence & promoted~ diseases cured & ?~ highly skilled (jobs created)~ foreign exchange~ socio economic benefits
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INPUTSR180 Million GovernmentR180 Million ExternalR360 Million
OUTPUTS700 Peer review publications300 Non-peer review publications (50% of health sciences in SA) 20 Patents 20 Technical reports 42 PhD graduates per annum 50 M graduates per annum
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Research Highlights Research Highlights
High Lead Levels in Paint on Children’s Toys
Health and Development Research Group
Identified the source of high blood lead levels in children;High lead levels in children’s toys;Worked with the National Department of Health to develop a strategy for information dissemination, policy formulation and eradication;
An example of research translation at its best.
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Chronic DiseaseChronic Disease
Three MRC Research Units• Chronic Diseases of Lifestyle• Health Promotion Research and Development• Exercise and Sports Science
Provided research data to inform • NDOH Vuka South Africa! Campaign• Youth Fitness Charter• NDOH National Strategy for Healthy Lifestyles
Disseminated the results of the NDOH-funded 2002 National Youth Risk Behaviour to communities, health professionals, educators and government. It is hoped to repeat this study, and the Global Youth Tobacco Survey in 2006.
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TuberculosisTuberculosis
Health Systems Research Unit Lay health workers (LHW) in the management of patients with TB;Randomized control trial; 8.7% higher successful treatment completion rates amongst workers on farms with LHWs compared to those without.
Centre for Molecular and Cellular Biology Molecular technique that reduces the time for diagnosis of multidrug resistant strains of TB from 60-90 days to 4-5 days
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HIV and AIDS, and Sexually HIV and AIDS, and Sexually Transmitted InfectionTransmitted Infection
Health Policy Research Group Quality of care provided by GPs in management of sexually transmitted infections (STIs);STIs are thought to be an important determinant of HIV transmission.
The Health Promotion Development and Research Group Behavioural science research project on the management of STIs by nurses in Port Elisabeth;Nurses are the most important ‘gatekeepers’ in informing and managing patients concerning STIs and HIV.
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AgeingAgeing
Response of elderly persons in coping with the demands of caring for orphans; Important policy implications for the Department of Social Welfare and the NDOH.
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TelemedicineTelemedicine
MRC/NDOH Telemedicine Lead ProgrammePractical and effective to set up telemedicine links to service nurse-directed Primary Health Care clinics in remote rural areas.
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Research Translation OfficeResearch Translation Office
Research translation officeBriefing that MRC scientists gave to Parliamentary Portfolio Committees on Health; and on Science and Technology.
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South African AIDS Vaccine InitiativeSouth African AIDS Vaccine Initiative
Outputs • effective, affordable locally relevant HIV vaccine• scientists plus the infrastructure of a sustainable vaccine biotechnology
industry in South Africa.
Probably the most impressive HIV vaccine development programme in the developing world.
Completed two Phase I clinical trials;Phase II trial later this year; Phase III clinical trails within the next few years.
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Alcohol and Drug AbuseAlcohol and Drug Abuse
MRC Alcohol and Drug Abuse Unit consistently highlights the devastating and increasing toll that alcohol and drug abuse have on the social fabric and health of South Africans;
Over 60% of crimes being committed under the influence of alcohol or drugs;
High levels of road traffic injury associated with alcohol abuse;Research data underpinning the Liquor Act;
Warning labels by NDOH on alcoholic drinks containers;
Work of the Central Drug Authority.
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Childhood DiarrhoeaChildhood Diarrhoea
4 - 5 million children die annually;
South Africa the annual death toll runs into the thousands;
The MRC Diarrhoeal Pathogens Unit at the University of Limpopo has just completed phase I trails of a new rotavirus vaccine for use across Africa;
Rotavirus is responsible for 25% of cases of childhood diarrhoea.
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Sexually Transmitted DiseaseSexually Transmitted Disease
The MRC Genital Ulcer Disease Research Unit confirmed the continuing decline in case of chancroid and primary syphilis; changes that may partly underlie the apparent stabilization in the rate of increase of the HIV epidemic.
The Unit Director also headed the expert team that investigated the recent outbreak of hospital acquired infection in KwaZulu Natal. The MRC is expanding its research efforts in this field.
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Vaginal Microbicides for HIV Vaginal Microbicides for HIV PreventionPrevention
The MRC HIV Prevention Research Unit has several clinical trials in various stages of progress;
Develop safe, effective, and affordable vaginal microbicides to prevent HIV infection and STDs;
Hopefully within a few years a proven agent will be available on the market to allow women to discreetly protect themselves from HIV infection even when their male sexual partner refuses to use protection.
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MalariaMalaria
MRC Malaria Research Lead Programme: the area of St Lucia in Kwazulu Natal has recently been declared malaria free - potential access for tourists;
Ten tenders worth R450 million for tourist activity in the area;
Incidence of malaria in the Lubombo Corridor between Mozambique and South Africa reduced through spraying with DDT – policy change at WHO;
Developing larvicidal agents against malaria using indigenous South African plants.
Indigenous Knowldege Systems Lead Programme – novel compounds for malaria from traditional medicines.
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Influenza-associated PneumoniaInfluenza-associated Pneumonia
The MRC Respiratory and Meningeal Pathogens Research Unit demonstrated that 30 – 40% of influenza-associated pneumonia in children in Soweto was caused by coinfection with Streptococcus pneumoniae, and that these episodes were prevented by administration of pneumoccocal conjugate vaccine.
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Conclusion Conclusion Just some of the highlights in the MRC research portfolio over the past 12 months.
The leading health research institution in South Africa, and one of the foremost in the developing world;
MRC’s rich panoply of research is bearing in solutions for the priority health problems that afflict South Africans;
Its transformation and capacity development initiatives continue to develop a growing cadre of health researchers – particularly Black African and women scientists.
We hope that with the trust placed in us, and the investments made in the MRC by the National Department of Health, Parliament, and the people of South Africa, the organization will continue to expand its efforts in conducting and promoting relevant and responsive health research for the benefit of all South Africans.
Prof A D MBewuPresidentMedical Research CouncilSeptember 27, 2005
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http://www.mrc.ac.zahttp://www.mrc.ac.za
Building a healthy nationBuilding a healthy nationthrough researchthrough research