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Nitrogenous base
Carbon ring structure found in DNA molecule
that contains one or more atoms of nitrogen
contains a ring of carbon with different amount of
nitrogen that connect in the middle of the ladder
by HYDOROGEN BONDS
These are the conections
A -----T
A----U
C---G
DOUBLE
HELIX
Shape of a DNA molecule consisting of two
strands of nucleotides that are twisted into a coil
and held together by the NITROGENOUS BASES
The shaped of a twisted ladder that is put
together by two strands of nucleotides and
connected by nitrogenous bases
DNA
REPLICATIONProcess in which the DNA in the chromosome is
copied before Mitosis and meiosis starts
A process where DNA makes an exact copy of
itself by UNZIPPING DOWN THE MIDDLE.
1. Enzyme unzips bases
2. Free floating
nucleotide bases
attach to open bases
of original DNA Strand
3. A different enzyme
connects nucleotides
messenger RNA
(mRNA)
One stranded RNA that carries information from
DNA in the nucleus to the cell’s cytoplasm
one stranded RNA that is a copied from DNA
and carries the information to the cell’s cytoplasm
ribosomal RNA
(rRNA)
RNA that makes up the ribosomes; binds to
mRNA and uses its information to assemble
amino acids in the right order
one stranded RNA that is a copied from DNA
and carries the information to the cell’s cytoplasm
Transfer RNA
(tRNA)
RNA that delivers amino acids to the ribosomes
to be assembled into proteins.
squiggly RNA that has the anticodon and an
amino acid attached to it that brings it to the
ribosomes to assemble into a protein.
Transcription
Process in the cell nucleus where a copy of RNA
is made from part of a DNA strand
IN the NUCLEUS this process make a RNA copy
from unzipped DNA strand.1. Enzymes unzip DNA
2. FREE RNA nucleotides
form base pairs with
their complimentary
nucleotides on DNA
strand
3. The mRNA strand
breaks away, DNA
strand rejoin
4. Introns (noncoding)
sequences are cut out
by enzymes before
mRNA leaves nucleus
and enters cytoplasmA connect U
C connect G
Codon
Group of three nitrogenous bases in mRNA that
code for one amino acid
3 letters on the mRNA strand that tells the tRNA
which amino acid to attach.
A connect U
C connect G
Translation
Process of changing the information in mRNA into
an amino acid chain in a protein,using rRNA and
tRNA
in the CYTOPLASM, mRNA is used to make a protein
with the help of bubble rRNA and squiggly tRNA
1. Bubbly rRNA attaches to start codon AUG on
mRNA strand
2. Squiggly tRNA finds the letters that fit with its
anticodon and carries over the amino acid
3. Methionine starts all proteins because it is the
start codon
4. A new squiggly tRNA molecule starts to attach
other amino acids according to the codon by a
PEPTIDE BOND
5. After peptide bond formed bubbly rRNA moves
over to the next codon and the used squiggly
tRNA is released. a new squiggly tRNA attaches
6. A chain continues to make a protein until the stop
codon is reached on the mRNA strand
Mutation
Any change in DNA sequence caused by errors
in replication, transcription, cell division, or by
external agents.
when the base pairs in a DNA sequence are
changed Mutation in the
gametes will be
passed on to
children
Mutation in the
body cells will
not be passed
on to the
children
Point shift mutation
A change in a single base pair in DNA that could
change the ONE AMINO ACID FOR THAT BASE
when the base pairs in a DNA sequence are
changed MAY ONLY CHANGE ONE AMINO
ACID
EX:
THE DOG BIT THE CAT.
THE DOG BIT THE CAR.
FRAME SHIFT
MUTATION
Mutation that occurs when a single nitrogenous
base is added or deleted from the DNA
sequence; causes a shift in the reading of codons
by one base
when one base in added or taken away from the
DNA sequence causing the codons to change
after that point on.
EX:
original:THE DOG BIT THE CAT.
deleted:THE DOB ITT HEC AT.
Added:THE DOT GBI TTH ECA T
Chromosomal
mutation
Mutation that occurs when parts of the
chromosomes break off during mitosis or meiosis
and join to the wrong chromosome, or join
backwards or in the wrong place on the
chromosme.
when pieces of chromosome break and off and
join to wrong chromosome, join backwards, or in
the wrong place.
mutagen
Any outside agent that can cause a change in
DNA;includes high temperature, radiation, or
chemicals
anything that causes a DNA to change; includes
xray, cosmic rays, ultraviolet radiation, and
nuclear radiation
Genetic
engineeringMethod of cutting DNA from one organism and
inserting the DNA fragment into a host organism
of the same or different species
cutting DNA from one organism into small
fragments and inserting the fragments into a host
organism of the same or different species.
EX: putting a firefly gene in a tobacco plant to
make it glow
Recombinant DNA
DNA made by recombining fragments of DNA
from different sources
cutting and pasting parts of DNA together from
the same organism or different organism
Restriction enzyme
DNA cutting enzyme that can cut both strands of
a DNA molecule at a specific nucleotide
sequence
an enzyme that can cut both strands of DNA into
pieces based on a certain order of bases
Plasmid
Small ring of DNA found in a bacterial cell that is
used as a biological vector
small ring of DNA from a bacterial cell that is
used to put a foreign DNA into another species
Gel electrophoresisA. Sample of DNA is cut up by
restriction enzymes
B. The gel that is firmer than
dessert jello is molded with
wells that DNA fragmented
sample is added to wells
C.An electric field is applied
make one end positive and
the other negative
D.Negatively charged DNA
fragments travel towards the
positive end. Smaller
fragments move faster and
farther
These are the
conections
A-----T
A----U
C---G