C-87 Nasal epithelium

• Respiratory segment– Pseudostratified epithelium

(Respiratory epithelium)• Ciliated cell, goblet cell, brush cell,

small granule cell, basal cell

– Lamina propia• A complex set of capillary loops,

mucous gland with serous demilune

– Periosteum of the adjacent bone

• Olfactory segment

• Olfactory segment– Pseudostratified epilthelium (olfactory epithelium)

• Olfactory cell (bipolar neuron), supporting cell, brush cell, basal cell,

much thicker than respiratory epithelium

– Lamina propia• Olfactory gland (bowman’s gland), myelinated nerve, unmyelianted nerve

– Periosteum of the adjacent bone

Compare : Olfactory epithelium Respiratory epithelium

• Goblet cell

• Nerve

• Thicker or thiner ( epithelium )

• ……

Compare : Olfactory epithelium Respiratory epithelium

Olfactory epithelium

Respiratory epithelium

Olfactory mucosa

A60 Nose, upper lip

• Vibrissae( hair follicles)

• Sebaceous glands

• Smooth muscle

• Mucous glands, serous glands

• Lots of blood vessels

A-100 Vocal cord

• Vocal fold, vocalis muscle, ventricle, ventricular fold (false vocal fold),

• Stratified squamous epithelium,

stratified columnar epithelium,

pseudostratified epithelium

• Mixed glands

• Hyaliane cartilage

• Vacalis muslce: skeletal muscle

vocalis muscle

vocal fold

ventricle

ventricular fold

B-24 Mammal trachea, cs

• Mucosa– Respiratory epithelium (ciliated cell,

goblet cell, etc), thick basement membrane – loose connective tissue

• Submucosa– Loose connective tissue, submucosal glands

• Cartilaginous layer, or muscular layer

• Adventitia

Trachea

B-25, 26, A-49 Lung

Bronchi

• Mucosa– Respiratory epithelium– Lamina propia

• Muscularis: SmM• Submucosa: glands• Cartilage layer: hyaline• Adventitia

Bronchioles

Epithelium pseudostratified epi., simple columnar epi., simple cuboidal epi.

Layer of smooth muscleLack of gland and cartilage plate

• Pulmonary acini– Terminal bronchiole: without goblet cell simple cuboidal epi, ciliated cell, clara cell– Respiratory bronchiole:

ciliated cell, clara cell, smooth muscle layer alveoli : gas exchange – Alveoli

• Alveolar duct• Alveolar sac• Alveoli

–Type I : thin squamous cells, 95% alveolar surface

–Type II : cuboidal cells, 5%–alveolar cell, capillary

Bronchioles Alveolar ducts & alvelar sacs

Bronchiole & respiratory bronchioles

Terminal brochioles

Clara cells

Respiratory bronchiole

Septal cellType II

Alvelus