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CORE - 316 patients, with coronary stenosis > 50% • Sensitivity - 85%• Specificity - 90%
ACC/AHA guidelines, JACC, june 2010
ACCURACY - 245 patients, with coronary stenosis > 50% – Sensitivity - 95%
– Specificity - 82%
ROTTERDAM - 360 pacients, with coronary stenosis > 50% – Specificity - 99%
– Specificity - 64%
Cardio CT - accuracy for calculation of coronary artery calcium score
CORE - 316 patients, with coronary stenosis > 50% • Sensitivity - 85%• Specificity - 90%
ACC/AHA guidelines, JACC, june 2010
ACCURACY - 245 patients, with coronary stenosis > 50% – Sensitivity - 95%
– Specificity - 82%
ROTTERDAM - 360 pacients, with coronary stenosis > 50% – Specificity - 99%
– Specificity - 64%
• However, all these studies focused on features describing mainly the global coronary tree, while the association between calcium score and the severity of coronary lesions in acute coronary syndrome (ACS) has not been described yet.
AIM OF THE STUDY
Correlation between the accumulation of calcium within the vessel wall of a coronary artery and the severity of coronary artery stenoses in patients who developed an acute coronary event.
Material and methods
29 patients
Group 1
Ca score < 100
7 patients
Group 2
Ca score 100 - 400
12 patients
Group 3
Ca score > 400
11 patients
CT: 1. calculation of coronary
calcium scoring
1. complex plaque analysis
Group 1 Group 2 Group 3
Mean calcium score(p<0.0001)
gr.1 25.08+/-21.94
gr.2 203.97+/-76.68
gr.3 808.8+/-369.48
.
Results
0
100
200
300
400
500
600
700
800
900
gr.1
gr.2
gr3
Mean ageMean age gr.1 60 years gr.2 65 years gr.3 64 years .
57
58
59
60
61
62
63
64
65
66
gr.1
gr.2
gr3
Ejection Fraction
Ejection fraction ( p=0.03)
Gr.1 54,33%
Gr.2 53% Gr.3 48,09%
3 vessel disease
Gr.1 16,7%
Gr.2 3,3%
Gr.3 27,3%
One single artery diseaseGr.1 83,3%Gr .2 58,3% Gr.3 9,1%
(p=0.02)
Location of the culprit artery
Left anterior descending
Gr.1 66,7%
Gr.2 66,7%
Gr.3 72,7%
Calcium score is significantly associated with the severity of coronary artery disease and can be used as a useful
prediction tool to evaluate the prognostic significance of coronary lesions in a non-invasive way.
Conclusions
