Upload
mia-welch
View
52
Download
0
Embed Size (px)
DESCRIPTION
Camera technology The selfie that can help me get pregnant. Selecting the right embryo to give you back is crucial if you are going to achieve a pregnancy after IVF/ICSI. We know that. Looks aren't everything. An embryo can look good but not have the potential to create a pregnancy. - PowerPoint PPT Presentation
Citation preview
Camera technologyThe selfie that can help me get pregnant
Selecting the right embryo to give you back is crucial if you are going to achieve a pregnancy after IVF/ICSI.
We know that.
• Looks aren't everything. An embryo can look good but not have the potential to create a pregnancy.
How can we assess an embryo’s potential ?
Time lapse imaging of the growth of each embryo.
• We examine the embryo growth very carefully for any abnormal growth events that will adversely affect its potential to create a pregnancy.
• A digital video recording is obtained for each embryo by taking a photograph every 10 mins.
• There are several systems that are able to do this
A video recording of each embryo is obtained for up to 6 days growth depending on how the embryos grow. Embryo selection is either made on day 3, 5 or 6. Most abnormal growth events are observed during the first and second cleavages
Key observation points currently correlated embryos least likely to create a pregnancy
• One cell to 3 cell (Video)• 2 cell to 5 cell (Video)• Re absorption of blastomeres (Video)• Fragmented or arrested development ( video)• Clear Abnormal development (Video)• Extended period between 3 cell and 4 cell (Graph)• Slow growth between key stages (Graph)• Poor overall morphology
Morphology assessment complements time lapse imaging data
Cleavage stage embryo
• Clear cells (Blastomeres) of equal size.• Correct number of blastomeres for the embryo age• Presence or absence of extra cellular fragmentation
Advanced stage embryo
• Expanded blastocyst showing clear and well developed ICM and trophectoderm by embryo age day 5 or 6.
Day 3 good Prognosis embryo Optimal growth curve, no abnormal growth events during the cleavage stages and good morphology
Very good Prognosis embryoOne that has reached a good quality blastocyst on day 5 or day 6 with no abnormal growth events and good cleavage morphology
Two examples demonstrating how we select the right embryos for transfer
Video 1• Embryo Selection at day 3 of culture using time lapse
• Video 2 Embryo Selection at day 5 of culture using time lapse and
morphology assessment