Cancer

Accelerated Biology

Learning Objectives

The different methods of diagnosing cancer.

The difference between a malignant tumor and a benign tumor.

The various causes of cancer.

Difference between oncogenes and tumor suppressor genes.

How does cancer spread to different parts of the body.

The current treatments for cancer

Hallmarks of cancerUncontrolled cell division

Evading Death (Apoptosis)

Hallmarks of cancer

Becoming immortal

Diagnosis

Biopsy

Diagnosis Contact Inhibition lost

Normal Cell

Cancer Cell

Diagnosis Extra chromosomes

Malignant Vs. Benign

Genetics and Cancer

Causes of CancerHow cells go bad?

Oncogenes

Cyclin

OncogenesTelomerase

(Cause of immortality)

Loss or gain of

function

in cancer?

Causes of cancerTumor Supressor gene

P53

Apoptosis

Cell cycle arrest

Repair of DNA

damage

Loss or Gain of function in Cancer?

How does Cancer Spread?

• Metastasis

• Angiogenesis

Current treatments for cancer

Radiation therapy

Chemotherapy

Surgery