Cartilage and Bone

Robert Scranton© 2008

Cartilage

Few or many cells? Cell name? Vascular? The dense CT covering is _________, except for around __________ Matrix-

CT+ ground substance Collagen, type___ GAG= “keratin/ chondroitin sulfate Chondronectain Bound water Territorial v. interterritorial

Cartilage

Perichondrium

Define it dense CT covering all cartilage

but articular

Layers

Functions: Nutrition Growth Repair Attachment point

Cartilage

Word Games

Cell nestsPerichondrial growthHypertrophyAlkaline phosphatase v.

hydroxyapatite crystalsFibrillin +elastin

Cartilage

Types

Hyaline, elastic, fibro Give location, characteristics

Type Location CharacteristicsHyaline articular, larynx, trachea, bronchi,

costalType II Collagen, GAGs, chondronectin, bound water

Elastic auricles, ext. auditory tube, eustachian tube, epiglottis

like hyaline, but with elastic fibers

Fibro Intervertebral disks, pubic symphysis, TMJ

like dense irregular CT, Collagen type I&II, very little ground substance

Cartilage

Hyaline

Cartilage

Hyaline

Cartilage

Elastic

Cartilage

Fibro

Cartilage

Example of Articular Cartilage

Bone

Epiphys

is

Diaphys

is

Metaphysis (in growing child)

Epiphys

is

Bone

Word Games

Compact bone= ____boneCancellous bone= ____ bone

and has ___ which are _____The space b/w trabeculae

and spicules filled with hematopoietic or fatty tissue.

DiploeImmature bone, give syn.

Found during

Secondary BoneOsteon

Bone

Periosteum & Endosteum

Periosteum, how many layers? 2- fibrous +osteogenic How does it attach to bone?

Sharpey’s fibers= Function?

Appositional growth Repair Attachment for ligaments and

tendons sensation

Bone

Periosteum & Endosteum

Endosteum, how many layers? What type of cells?

osteoblasts

Bone

Name the major players Osteoblasts Osteocytes Osteoclasts Matrix

Bone

Name the major players Osteoblasts

Active, mitotic Osteocytes Osteoclasts Matrix

Bone

Name the major players Osteoblasts Osteocytes

Surrounded by matrix Can’t divide Lacunae & canaliculi

Osteoclasts Matrix

Bone

Name the major players Osteoblasts Osteocytes Osteoclasts

Derived from? Function? Located in? Synthesize and secrete?

Matrix

Bone

Name the major players Osteoblasts Osteocytes Osteoclasts

Derived from? Function? Located in? Synthesize and secrete?

Matrix

Bone

Name the major players Osteoblasts Osteocytes Osteoclasts Matrix

Inorganic> Organic Inorganic- hydroxyapatite, rigidity Organic- Type I collagen, GAG,

elasticity Bone is vascular

The Haversian System

The Volkmann’s Canal

The Haversian System

Haversian CanalHaversian Canal Volkmann’s CanalVolkmann’s Canal

Bone

Hormone Effects

Hormone Effects

Hormone Effects

Don’t neglect

Section on Spongy BoneJoints

What is the origin of the secretory epithelial lining the joint space