ULTRABONDSPECIES

Mycotoxin Control System POULTRY

PIGS

CATTLE

PREMIUM QUALITY FEED-ENHANCER

PERENNIAL RYEGRASS,GRASSES, OATS,WHEAT, BARLEY

ERGOTS(Ergot Alkaloids) ERGOTS

WHEAT, MAIZE, BARLEY,OATS, GRASS SILAGE,

WHOLE CROP SILAGE,CEREAL & MOIST

BY-PRODUCTS, STRAW

FIELDMYCOTOXIN(Fusarium)

TRICOTHECENESDeoxynivalenol (DON) T2 Toxin

ZEARALENONE(ZON)

FUMONISINSFumonisin B1 (FB1)

SOYA, OATS, STRAW, SOYA BY-PRODUCTS,

WHEAT, MAIZE, BARLEY,CEREAL BY-PRODUCTS,

GRASS SILAGE

STORAGEMYCOTOXIN(AspergillusPenicillium) OCHRATOXINS

Ochratoxin A (OTA)

AFLATOXINSAflatoxin B1 (AFB1)

Why worry about Mycotoxins?

Mycotoxins are toxic by-products produced by

fungi that develop in crops either in the field or

during storage. Mycotoxins can be very harmful

to cattle, pigs and poultry at extremely low levels,

commonly measured in parts per billion (ppb).

Over the years improved genetics have resulted in

increased performance of livestock, leading to much

higher producer expectations. Mycotoxins are one of the

issues that can seriously affect health, performance and

profitability. Modern livestock have a much higher feed

intake than at any point in the past and as a consequence,

mycotoxins can have a much greater impact.

Mycotoxins are everywhereRecent research has highlighted just how prevalent mycotoxins are. They can be found in all feed raw materials and occur both in the field and during storage.

The six major mycotoxins and some of their effects on animals and birds:

• Aflatoxin – scouring/blood in faeces, reduced fertility and weight gain, decreased egg production

• Deoxynivalenol – symptoms include reduced appetite

• Zearalenone – leg swelling, reduced appetite, reduced fertility

• Ochratoxin – abortions, reduced appetite

• Fumonisin – respiratory problems, reduced appetite, increased mortality

• T2 – infertility, lameness, increased disease susceptibility, reduced egg quality

Due to a huge amount of misinformation in the area of mycotoxins and mycotoxin control systems, Optivite has undertaken substantial research to provide clarity for the global farming industry.

A specialist independent laboratory was used to test the binding capacity of mycotoxin control agents available on the market. In order to overcome any inclusion rate effects, products were compared on microgram of toxin bound per gram of toxin binder. The research proved

born out of researchULTRABOND...

“There are around 500 known mycotoxins to date, and this number continues to grow. The synergistic toxic effect of these mycotoxins and their impact on animal performance is only just beginning to be understood.”(Hyden M + Broom L, All About Feed, 2014)

that not all mycotoxin control agents are the same and many are not as good as assumed.

As a result of this independent testing, Optivite formulated Ultrabond, a unique mycotoxin control system that binds more toxins per gram than competitor products.

Ultrabond will not interfere with supplements, medication, vitamins or other nutrients.

ULTRABOND:

HOW DOES ULTRABOND WORK?

The Science

What is Ultrabond?Ultrabond is a revolutionary, broad spectrum, low inclusion mycotoxin control system. It consists of a synergistic blend of selected natural minerals and bioflavonoids. The natural minerals provide effective control against aflatoxins, ochratoxins, fumonisins, zearalenone, deoxynivalenol and the dangerous T-2 toxins. Bioflavonoids are powerful natural antioxidants that support liver function, the body’s principal organ of detoxification.

Why use Ultrabond?Sampling for mycotoxins is prone to error as they are not distributed uniformly throughout the feed or raw material. The margin for error has been reported to be greater than 80% (ref: USDA) indicating that, at best sampling can be a hit or miss affair. The routine use of an effective broad spectrum mycotoxin control system such as Ultrabond is therefore the only way to ensure adequate protection.

It is important to understand that not all mycotoxin control agents are the same. Certain products are successful at controlling a limited range of mycotoxins only; however, mycotoxins are seldom present in isolation. It is imperative therefore to select a broad spectrum binder with proven success.

Ultrabond provides the broadest binding capacity of any product commonly used on the market.

Ultrabond... Proven results

Comparison of mycotoxin binding capacities of commonly used mycotoxin control systems

The total toxin bound by Ultrabond is 51.8% greater than the next best control system.

How are dairy cows and beef cattle exposed to mycotoxins?

• Freshpasture

• Allsilagesincludinggrass,hay,whole grains and maize

• Beddingfibressuchasstraw

• Feedconcentratesformulatedwith contaminated grain

• Moistfeedproducts

The greatest exposure to toxins by cows comesfromforage.InatypicalTMRformulation the majority of mycotoxin loading is likely to come from the forage.

Ensiled forages are more likely to harbour fungi and associated mycotoxins than dry forages, especially poorly made silages, where the fermentation and anaerobic conditions are not strictly controlled. Even well ensiled forages can present problems as the higher sugar content can provide nutrients for fungus to grow.

Cereals, grains and proteins can also harbour toxins that are difficult to test for. Often, even when batches are found to contain toxins, by the time the test results are confirmed the product has been fed. Continuous exposure to mycotoxins can also be introduced via bedding. Cows which are fed below appetite often consume significant quantities of bedding and are therefore at particular risk.

(Internal data, UK dairy farm, 2013)

The economic cost of mycotoxins

Research on the effects of mycotoxins in dairy cattle have shown:

Reduced milk production of

1.4kg/h/d*

FORAGE

87.34%CONCENTRATES

12.66%

Increased somatic cell

count of

40,000**Korosteleva.S.N, Smith. T.K, Boermans.H.J, 2008, Effects of feed naturally contaminated with fusarium mycotoxins on metabolism and immunity of dairy cows, Journal of Dairy Science, volume 92, Issue 4, Pages 1583-1593).

*Chi.F, Broomhead. J, Mycotoxins and Dairy Cattle, A Review for Dairy Producers, 21/01/14.

CATTLE:

per ml**

o

20o

40o

60o

80o

100o

120o

140o

160oTOXIN BINDING (µg/g product)

MO

NTM

ORI

LLO

NIT

E+

YEAS

T CE

LL W

ALL

CLIN

OPT

ILO

LITE

MO

NTM

ORI

LLO

NIT

E+

ALGA

E EX

TRAC

T

AUST

RALI

ANBE

NTO

NIT

E

HSC

AS +

YEA

ST C

ELL

WAL

L + P

LAN

T EX

TRAC

T

MO

NTM

ORI

LLO

NIT

E +

BEN

TON

ITE

+YE

AST

CELL

WAL

L

YEAS

T CE

LL W

ALL

ULT

RABO

ND

Inclusion rates

Higher inclusion rates may be required from those stated above for a severe mycotoxin challenge. Please consult your Optivite nutritionist for further advice.

20g/head/day

DAIRY / BEEF

0.5 - 1kg/t

SWINE & POULTRY

CONTINUOUS USE: CONTINUOUS USE:

1 - 5kg/tIDENTIFIED MYCOTOXIN CHALLENGE:

Pigs are not only at risk from feeds and feed ingredients, but those housed in straw based systems can have a higher exposure to mycotoxins as they often consume significant quantities of bedding. Straw quality should therefore be considered a high risk factor. While some feeds may represent a relatively low risk of mycotoxin exposure, what is important is the overall loading on the animal on a daily basis.

Research has shown the presence of mycotoxins in diets can have a significant effect on growing pig performance.

(Andretta et al., 2012; Animal)

(Kanora & Maes, 2009)

Mycotoxinconsumptioninthebreedingherdis also associated with significant costs:

Poultry are at risk from feeds and feed ingredients, with younger birds being more susceptible. Mycotoxinsareknowntosuppressimmunity (Awad et al, 2013) which can impair vaccination efficacy resulting in increased disease susceptibility. This has particular relevance in broiler production.

Research has shown the presence of mycotoxins in diets can have a significant effect on poultry performance.

Ultrabond can bind to these mycotoxins in feed to prevent them from being absorbed by the animal, thus reducing the risk to performance.

Aflatoxins and Ochratoxins had the most detrimental effect on feed intake and growth

Increased weight of the liver, kidney, lung and gizzard

Mortality was 9 times higher in broilers fed diets containing DON and 3 times higher in broilers fed diets containing aflatoxin

(Andretta et al 2011)

PIGS:

POULTRY:

FERTILITY

each 21 day return costs

(BPEX)

£50per sow

FCR + LWG

the negative impact on FCR costs an additional

2-3pper kilo

(Internal research)

REDUCED APPETITE

Every 1ppm of DON reduces feed intake by

7.5%(Vilgoen)

approx.

What are mycotoxins costing pig farmers?

Reduced feed

intake by Reduced feed

intake byReduced weight gain by

Reduced weight gain by

The effect of mycotoxins on growth was found to be

greater in young animals

Poorconception rates

Poorsemen quality

Reducedlitter sizes

18%12%21% 14%

ULTRABOND:

The SupportOptivite distributor countries

ContactOptivite Manton Wood Enterprise Park Worksop, S80 2RS, UK www.optivite.com

Email: info@optivite.com international@optivite.com

t: +44 (0)1909 537380 f: +44 (0)1909 478919

Optivite provides cutting-edge, science based products plus the support you need. Optivite’s nutritionists and animal husbandry specialists are available with expert advice, service and product knowledge, with regional sales and technical support people on-hand to assist with day-to-day challenges. What’s more, our global distributor network is here to guide you to the right product choices wherever you are in the world.