CCMH Drug Study

8/13/2019 CCMH Drug Study

1/5

Generic

Name(Brand

Name)

Indication Dosage

& Frequency

Mechanism of

Action

Side Effects Nursing

Responsibilities

LithiumCarbonate(Litcab)

Classification:Mood

Stabilizer

Prophylaxis ofmanic disorder(bipolardisorder).

1.5-2 g dailymay be given

for the first 5-7days.

To treat bipolarmanic-depressive

psychosis,

manicepisodes.

Ataxia Tremor Muscle

hyperirrita

bility

Slurredspeech

Psychomotor

retardation

Blurryvision

Direct client toavoid potentiallydangeroussituations, such as

driving.

Instruct the clientto promptly report

symptoms to the

health care

provider.

Inform clientabout EPS.

Advise client torise slowly from

sitting or lying tostanding to

prevent sudden

decrease of bloodpressure.


2/5

Generic

Name(Brand

Name)

Indication Dosage

& Frequency

Mechanism of

Action


Responsibilities

Chlorpromazine(Thorazine)

Classification:Psychotic

drugs

Managementfor psychoticdisorders,manic

depressivedisorders.

10 mg TID

Blockdopaminereceptors in the

brain; also alter

dopaminerelease and

turnover.

Agitation Drowsines

s

Agranulocytosis

Extrapyramidal

effect

Posturalhypotensio

n

Assess mentalstatus prior to andperiodicallyduring therapy.

Monitor BP andpulse prior to andfrequently during

the period of

dosage

adjustment..

Observe patientcarefully whenadministering

medication, toensure that

medication is

actually taken andnot hoarded.

Assess patient forsigns and

symptoms of

dehydration.


3/5

Generic

Name(Brand

Name)

Indication Dosage

& Frequency

Mechanism of

Action


Responsibilities

Risperidone(Risperdal)

Classification:

AtypicalAntiPsychotic

drugs

Treatment of abroad range ofpatients withschizophrenia.

2 mg OD

May act asantagonizingdopamine and

serotonin in

CNS.

Insomnia Anxiety Agitation Dizziness Fatigue Blurred

vision

Direct client toavoid potentiallydangeroussituations, such as

driving.

Instruct the clientto promptly report

symptoms to the

health care

provider.

Inform clientabout EPS.

Advise client torise slowly from

sitting or lying tostanding to

prevent sudden

decrease of bloodpressure.


4/5

Generic

Name(Brand

Name)

Indication

Dosage &

Frequency

Mechanism of

Action


Responsibilities

Carbamazepine(Tegretol)

Classification:

Anticonvulsant

Indicatedfor acutemania andbipolar

affectivedisorder.

400-1600mg/day

given in 2-3

divided

doses.

Carbamazepinestabilizes theinactivated state

of Voltage-gated

sodium channels,making fewer of

these channels

available to

subsequentlyopen. This leaves

the affected cells

less excitable untilthe drugdissociates.

Carbamazepine

potentiates GABAreceptors made up

of alpha1, beta2,

gamma2 subunits.This may be

relevant to its

efficacy in

neuropathic painand manic-

depressive illness.

Dizziness Ataxia Leukopeni

a

Fatigue

Administermedication withfood to minimizegastric irritation.

Do not crush or

chew extended-release tablets.

If a dose ismissed, take as

soon as possiblebut not just before

next dose; do notdouble doses.

Medicationshould be

gradually

discontinued toprevent seizures.

Instruct patientsthat fever, sore

throat, mouth

ulcers, easy

bruising,petechiae, unusual

bleeding shouldbe reported.

Advise patient notto take alcohol or

other CNSdepressant

concurrently with

this medication.


5/5

Generic

Name(Brand

Name)

Indication Dosage

& Frequency

Mechanism of

Action


Responsibilities

DivalproexSodium(Depakotel)

Classification:Anticonvulsant

Treatment foracute manic ormixed episodesassociated with

bipolardisorder withor without

psychotic

features.

25 mg/kg/day

Increases levelofgamma/amino

butyric in

brain, whichdecreases

seizure activity.

Dizziness Ataxia Tremor Abnormal

gait

nervousness

Assess for GIcomplaints. Assess for pain. Assess for

changes in bowel.

Assess for EPS. Instruct the

patient to inform

physician oftransient intestinal

cramps, increased

plasma prolactinlevels and EPS

occur.

Documents

CCMH Drug Study