Initials of patient: R.ADate of Admission: Age: 48 years
oldDiagnosis: Cerebral MalariaSex: MDate medication
started:DRUGMECHANISM OF
ACTIONINDICATIONCONTRAINDICATIONADVERSE/SIDE EFFECTSNURSING
RESPONSIBILITIES
Generic Name:Ceftriaxone
Brand Name:Omnicef
Classification:Antibiotic
Dosage:300 mg
Route:Oral
Frequency:OD
Form:capsule
Color:BlueWorks by inhibiting the mucopeptide synthesis in the
bacterial cell wall. The beta-lactam moiety of Ceftriaxone binds to
carboxypeptidases, endopeptidases, and transpeptidases in the
bacterial cytoplasmic membrane. These enzymes are involved in
cell-wall synthesis and cell division. By binding to these enzymes,
Ceftriaxone results in the formation of of defective cell walls and
cell death UTI; lower respiratory tract, bone or joint,
intra-abdominal, skin, or skin structure infection; septicaemia
Contraindicated in patients hypertensive to drug or other
cephalosporins
Side effects: GI: diarrhea Hematologic: eosinophilia,
thrombocytosis Skin: pain, induration, tenderness at injection
site, rash Other: hypersensitivity reactions, serum sickness
Adverse effect: GI: psuedomembranous colitis Hematologic:
Leukopenia Other: anaphylaxis
Pre-administration Check doctors order Observe 10 Rs Obtain
specimens for culture and sensitivity before initiating
therapy.Intra-administtration Hold medication if there is
anaphylaxis or allergic reactions
Post administration: Document Observe for adverse reactions
