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Cell Facts and Tissues (rev 3-10)
Cells are the smallest structural and functional unit of life• All cells are surrounded by a thin, outer membrane called
the plasma membrane (PM).– This separates the cell from interstitial fluid which
bathes the outside of the cell.• On the inside of the cell is a gel-like fluid called
cytoplasm. This contains specialized structures called organelles and the nucleus, a small circular body.
The Plasma Membrane • Forms the outer boundary of the cell
– Composed of 2 layers of fat molecules called phospholipids and another kind of fat molecule called cholesterol
Cell Facts & Tissues-BIO 006 1
Cell Facts & Tissues-BIO 006
• The plasma membrane (PM) keeps the cell whole and intact– It serves as a gateway (entrance) between the fluid
inside and outside the cell– It identifies a cell as belonging to one particular
person; the cell’s surface proteins act as identification tags (each person has different surface proteins)
Cytoplasm: composed of a gel-like fluid called cytosol
– Lies between the PM and the nucleus– Contains Organelles: structures with specialized
functions which are located in the cytoplasm.• Also contains a nucleus.
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Cell Facts & Tissues-BIO 006
Nucleus:
• Controls every organelle in the cytoplasm and the cell reproduction process because it contains the genetic code—instructions for making proteins, which in turn determine cell structure and function
• directs all functions of the cell.
Structural features:
• Outer surface is a double-layered nuclear membrane, also called nuclear envelope.
• Contains 46 chromosomes which contain DNA, the genetic code
Figure 3.19a3
Cell Facts & Tissues-BIO 006
Organelles
Ribosomes: tiny particles found throughout the cell; responsible for making enzymes and other protein compounds– Made up of 2 tiny subunits mostly made up of a
special kind of RNA— called ribosomal RNA – Ribosomes may be attached to the Endoplasmic
Reticulum– Free floating ribosomes produce proteins for use
by the cell
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Cell Facts & Tissues-BIO 006
Endoplasmic reticulum (ER) is a system of membranes forming a network of connecting sacs and canals that wind back and forth through a cell’s cytoplasm. – manufactures proteins and chemical compounds
produced by the cell.– The sacs and canals carry proteins and other
substances through the cytoplasm of the cell from one area to another.
Types: rough and smooth• Rough ER: areas where the surface is dotted with
ribosomes– Rough ER receives, from the ribosomes, and
transports newly made proteins • Smooth ER: Areas without ribosomes
– These areas synthesize chemicals and make new cell membrane
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Cell Facts & Tissues-BIO 006
Golgi Apparatus
• Group of flattened sacs• Called the chemical processing and packaging
center because it collects chemicals from the smooth ER in vesicles
Mitochondria: • Provide most of the power for cellular work;
nicknamed the cell’s “power plant”• Enzymes found in the mitochondria use oxygen
to breakdown glucose to release energy
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Cell Facts & Tissues-BIO 006
Lysosomes • contain digestive enzymes that digest food compounds
as well as other substances.– Can destroy microbes
Centrioles: used in cell division
Cilia: fine, hairlike extensions on the free surface of some cells; are capable of movement
Flagella: is a single projection from the cell surface; is
larger than cilia; “tails” of sperm cells are the only example of flagella in humans
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Cell Facts & Tissues-BIO 006
Movement of Substances through Cell Membranes
• Occurs through passive or active transport• Energy is required only for active transport and
is obtained from adenosine triphosphate or ATP– ATP is produced in the mitochondria
• Passive transport processes do not require added energy and result in movement “down a concentration gradient”
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• Solution terms
– Solute is a substance that dissolves into another substance
– Solvent is a substance in which other substances are dissolved
Cell Facts & Tissues-BIO 006 9
Cell Facts & Tissues-BIO 006
Passive Transport
• Transports a molecule without requiring the cell to use any energy; requires that there be a difference in concentration between 2 areas, called a concentration gradient.
• Movement is from area of high to area of low concentration or “down” the concentration gradient
• Primary passive transport processes are diffusion and osmosis
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• Diffusion : movement of molecules from one region to another as a result of random movement; – Molecules move from the area of higher
concentration to the area of lower concentration
• molecules scatter themselves evenly throughout a solution
Cell Facts & Tissues-BIO 006 11
Diffusion
Cell Facts & Tissues-BIO 006
(Passive transport: no energy required)
• Diffusion: movement from area of high concentration to low
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Cell Facts & Tissues-BIO 006
Osmosis is the diffusion of water across a selectively permeable membrane (the solutes cannot cross the membrane) from the region of lower concentration to the area of higher concentration
• Selectively permeable means a membrane will permit some substances to pass through it but not others
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Cell Facts & Tissues-BIO 006 14
Cell Facts & Tissues-BIO 006
Active transport• Movement of substances is “up the concentration
gradient”— movement from an area of lower to higher concentration
• Requires energy from ATP
• Ion pumps– An ion pump is a protein structure in the cell
membrane• Is called a “carrier”
– Ion pumps use energy from ATP to move substances across cell membranes against their concentration gradients
– Examples: sodium-potassium pump, calcium pump– Some ion pumps work with other carriers so that
glucose or amino acids are transported along with ions
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Cell Facts & Tissues-BIO 006
Na+-K+ Pump
3 sodium ions are pumped out of the cell and 2 potassium ions are pumped in during a pumping cycle of the carrier molecule. ATP is broken down and used for energy to pump the ions
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• Why are passive and active transport important in the human body?
– Hint: how do substances move across the plasma membrane?
Cell Facts & Tissues-BIO 006 17
Cell Facts & Tissues-BIO 006
Body Tissues• Tissue: group of similar cells that perform a
common function• 4 main kinds of tissues
– Epithelial– Connective– Muscle– Nervous
• Tissues differ from each other in their– Size and shape of cells– Amount and kind of material between the cells– Special functions they perform
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Cell Facts & Tissues-BIO 006
Epithelial Tissue covers the body and lines body cavities– Cells packed closely together
• Can be categorized according to shape:– Squamous (flat)– Cuboidal (cube)– Columnar (tall)
• Can be categorized according to arrangement-layers of cells:– Simple– Stratified
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Cell Facts & Tissues-BIO 006
EPITHELIAL TISSUE• Absorbs
– substances can easily pass through it for exampleabsorption of oxygen into the blood
• Secretes– cells function in clusters and form glands which
make and release substances to help the body work i.e. saliva, digestive juices, and hormones
– cells forms the urine-producing tubules of the kidneys
• Protects tissues– when there are several layers of closely packed
cells, microorganisms can’t get through them – cilia move mucus and protect against entry of
foreign particles into the lung
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Cell Facts & Tissues-BIO 006
• Most abundant tissue in body Most widely distributed tissue in body Multiple types, appearances, and functions
- Connects tissues to each other- Forms a supportive framework for the body
and the organs- Transports substances throughout the body
(blood is a type of connective tissue)- Defends us against microorganisms
Relatively few cells in an intercellular matrix
Connective tissue
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Cell Facts & Tissues-BIO 006
Types of Connective Tissue
• Blood— fluid “tissue”; – function is transportation and protection– cells are suspended in a fluid matrix called plasma.
(Considered a connective tissue because all blood cells derive from earlier stem cells located within bone.)
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Areolar: glue that holds organs togetherMost widely distributed type of connective tissue
Cell Facts & Tissues-BIO 006 23
Cell Facts & Tissues-BIO 006
Adipose (fat)• specialized to store lipids•Oil filled cells
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Cell Facts & Tissues-BIO 006
Dense Fibrous•Has bundles of collagen fibers arranged in parallel rows•Provides strength and flexibility; does not stretch •example is tendons and ligaments
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Cell Facts & Tissues-BIO 006
Bone• functions in support and protection
•Stores the mineral calcium
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Cell Facts & Tissues-BIO 006
Cartilage•bone will be formed from this type tissue•Matrix is the consistency of firm plastic or a gel
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Cell Facts & Tissues-BIO 006
Muscle tissue:
movement “specialist”; can contract
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Cell Facts & Tissues-BIO 006
Skeletal Muscle•also called striated or voluntary; •attaches to bones; •Has striations• is multinucleated• has long cells
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Cell Facts & Tissues-BIO 006
Cardiac Muscle
• also called striated or involuntary
• forms the walls of the heart
•has intercalated disks; fibers branch
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Cell Facts & Tissues-BIO 006
Smooth
•also called nonstriated, visceral, or involuntary
• found in blood vessel walls and hollow organs
• push food and fluids through body
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Cell Facts & Tissues-BIO 006
Nervous tissueprovides rapid communication between body structures
and control of body functions Consists of 2 types of cells:
Neurons—conducting cells Neuroglia—supportive and connecting cells
Neurons Cell components
o Cell bodyo Axon (one or more) carries nerve impulses
away from cell bodyo Dendrites carry nerve impulses toward the
cell body
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