Cell Membrane 100 online.ppt

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    Plasma Membrane

    Structure andFunction

    Chapter 4

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    Outline

    Phospholipid Bilayer Fluid Mosaic Model

    Membrane Proteins

    Diffusion

    Facilitated Diffusion

    Osmosis Bulk Transport

    cti!e Transport

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    Membrane Functions

    Protection

    Communication

    Selecti!ely allo" substances in #espond to en!ironment

    #eco$nition

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    Plasma Membrane

    Boundary that separates the living cellfrom it%s

    non-livingsurroundin$s&

    Phospholipid bilayer

    Amphipathic' ha!in$ both(

    hydrophilic heads

    hydrophobic tails

    )* nm thick

    +s a dynamic structure

    PhospholipidPhospholipid

    http://www.d.umn.edu/~sdowning/Membranes/phospholipidlateralmovanim.htmlhttp://www.d.umn.edu/~sdowning/Membranes/phospholipidlateralmovanim.html
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    Fluid'Mosaic Model

    http://www.youtube.com/watch?v=Qqsf_UJcfBc&mode=user&search=http://telstar.ote.cmu.edu/biology/animation/Membranes/membranes.htmlhttp://www.youtube.com/watch?v=Qqsf_UJcfBc&mode=user&search=
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    Proteins,For Function

    Transport

    #eceptors

    -n.ymes

    Si$nal Transducers

    Support

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    PROTEINS CA

    N MOVE IN THE MEMBRANE

    , TOO!

    Plasma Membrane Proteins

    http://www.d.umn.edu/~sdowning/Membranes/proteinmobilityanim.htmlhttp://www.d.umn.edu/~sdowning/Membranes/proteinmobilityanim.htmlhttp://www.d.umn.edu/~sdowning/Membranes/proteinmobilityanim.htmlhttp://www.d.umn.edu/~sdowning/Membranes/proteinmobilityanim.htmlhttp://www.d.umn.edu/~sdowning/Membranes/proteinmobilityanim.htmlhttp://www.d.umn.edu/~sdowning/Membranes/proteinmobilityanim.htmlhttp://www.d.umn.edu/~sdowning/Membranes/proteinmobilityanim.htmlhttp://www.d.umn.edu/~sdowning/Membranes/proteinmobilityanim.html
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    Channel protein

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    Carrier protein

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    Cell reco$nition protein

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    #eceptor protein

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    -n.ymatic protein

    Exampleof

    Enzymaticactiityaociate"

    #it$ amem%&ane'

    G-proteiG-protei

    ()PROTEINANIMATION*

    G-protein anG-protein animation 3imation 3

    http://www.sp.uconn.edu/~bi107vc/images/anim/SigtranRA.gifhttp://www.sp.uconn.edu/~bi107vc/images/anim/SigtranRA.gifhttp://www.rpi.edu/dept/bcbp/molbiochem/MBWeb/mb1/part2/signals.htmhttp://www.rpi.edu/dept/bcbp/molbiochem/MBWeb/mb1/part2/signals.htmhttp://www.sp.uconn.edu/~bi107vc/images/anim/SigtranRA.gifhttp://entochem.tamu.edu/G-Protein/index.htmlhttp://entochem.tamu.edu/G-Protein/index.htmlhttp://entochem.tamu.edu/G-Protein/index.htmlhttp://www.sp.uconn.edu/~bi107vc/images/anim/SigtranRA.gifhttp://www.sp.uconn.edu/~bi107vc/images/anim/SigtranRA.gifhttp://www.sp.uconn.edu/~bi107vc/images/anim/SigtranRA.gifhttp://www.sp.uconn.edu/~bi107vc/images/anim/SigtranRA.gifhttp://www.sp.uconn.edu/~bi107vc/images/anim/SigtranRA.gifhttp://www.sp.uconn.edu/~bi107vc/images/anim/SigtranRA.gifhttp://entochem.tamu.edu/G-Protein/index.htmlhttp://entochem.tamu.edu/G-Protein/index.htmlhttp://entochem.tamu.edu/G-Protein/index.htmlhttp://www.rpi.edu/dept/bcbp/molbiochem/MBWeb/mb1/part2/signals.htmhttp://www.rpi.edu/dept/bcbp/molbiochem/MBWeb/mb1/part2/signals.htm
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    Permeability of the Cell Membrane'

    +ie&entially Pe&mea%le+ie&entially Pe&mea%le

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    Permeability of the Cell Membrane

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    Diffusion

    / the passivemo!ement of molecules from

    a hi$her to a lo"er concentration untilequilibriumis reached&

    / 0o" can "e e1plain diffusion2

    / 3ases mo!e throu$h plasma membranesby diffusion&

    Osmosis/ special case of diffusion

    D+FFS+O5

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    Process of diffusion

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    3as e1chan$e in lun$s by diffusion

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    Osmosis

    The diffusion of "ater across a

    differentially permeable

    membrane due toconcentration differences

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    Question:

    Whats in a Solution?Answer:

    solute 6 solvent

    solution

    a!l 6 "#$ saltwater

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    TO5+C+T7

    #efers to the concentration of

    S%&'()S

    +s a*)&A(+,) term8 comparin$ t"odifferent solutions

    0ypertonic

    0ypotonic

    +sotonic

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    "ypertonic

    solution"ith a greater solute

    concentrationcompared to another solution&

    . a!l

    /0. "#%

    *ed 1lood !ell

    2. a!l

    /2. "#%

    solutionsolution

    -$ic$#ay

    #illt$e#ate&moe

    .

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    "ypotonic

    solution"ith a lower solute concentration

    compared to another solution&

    . a

    /0. "#%

    *ed 1lood !ell

    3. a

    //. "#%

    solutionsolution

    -$ic$#ay

    #illt$e#ate&moe

    .

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    +sotonic

    solution"ith an e4ual solute concentration

    compared to another solution&

    . a

    /0. "#%

    *ed 1lood !ell

    . a/0. "#%

    solutionsolution

    -$ic$#ay

    #illt$e#ate&moe

    .

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    +SOTO5+C SO9T+O5

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    07POTO5+C SO9T+O5

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    07P-#TO5+C SO9T+O5

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    Function,Transport& re specific8

    combine "ith only a certain type of

    molecule& Types

    /Facilitated transport''passi!e

    /cti!e transport,re:uires ener$y

    Carrier Proteins

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    Facilitated Transport

    http://www.d.umn.edu/~sdowning/Membranes/diffusionanimation.htmlhttp://www.wiley.com/legacy/college/boyer/0470003790/animations/membrane_transport/membrane_transport.htmhttp://www.d.umn.edu/~sdowning/Membranes/diffusionanimation.html
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    cti!e Transport

    http://www.wiley.com/legacy/college/boyer/0470003790/animations/membrane_transport/membrane_transport.htmhttp://www.wiley.com/legacy/college/boyer/0470003790/animations/membrane_transport/membrane_transport.htm
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    The sodium'potassium pump

    - t i d

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    -1ocytosis'''Cellular secretion

    -ndocytosis,

    /Pha$ocytosis, ;Cell eatin$