Cell Structure and its Environment.ppt

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    Cell Structure and

    its Environment

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    Early Discoveries

    During 1665, Robert Hooke observed and

    described cells in cork

    Tiny compartments = cellulae

    Small rooms

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    Early Discoveries

    Antonie Van Leeuwenhoek

    - improves microscope

    - first to observe and describe the single-

    celled organisms

    (animalculesmicroorganisms)

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    Early Discoveries

    Robert Brown (1831)published observationsreporting the discovery and widespreadoccurrence of nuclei in the cells

    Matthias Schleiden (1838)Discovered thatplant parts are made of cells

    Theodore Schwann (1839)Discovered that

    animal parts are made of cells Rudolph Virchow (1855)Stated that all living

    cells come only from other living cells

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    Cell Theory

    1) Every organism is composed of one or

    more cells2) Cell is smallest unit having properties of

    life

    3) Continuity of life arises from growth and

    division of single cells

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    Cell

    Smallest unit that lives on its own

    Each cell is structurally organized for

    metabolism

    Potential to reproduce

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    Types of Cell

    Prokaryotic cell

    Eukaryotic cell

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    Prokaryotic cell

    Smallest known cell

    Tiny volume of cytoplasm

    Membranes dont enclosed DNA

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    Parts

    Or capsule

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    Eukaryotic cell

    Present in plants, animals and fungi

    Has organelles and nucleus

    Animal cell Plant cell

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    Structural Organization of Cells

    Plasma membrane

    Nucleus

    Cytoplasm

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    Plasma Membrane

    Selectively isolates the cells contents from

    the external environment

    Regulates the exchange of essentialsubstances between the cells contents

    and the external environment

    Communicates with other cells

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    Plasma MembraneLipid Bilayer

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    Membrane Proteins

    Proteinpump across

    bilayer

    Proteinchannel

    across bilayer

    Protein pump

    Recognitionprotein

    Receptorprotein

    extracellularenvironment

    cytoplasm

    lipid bilayer

    Figure 4.4Pa e 57

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    Membrane Proteins

    proteins

    double layer of lipids

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    Why arent all cells big?

    The smaller or narrower the cell, the more

    efficiently materials cross its surface and

    become distributed through the interior.

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    Common Features of Eukaryotic

    Cells Nucleuslocalizing the cells DNA

    Endoplasmic reticulumprotein and lipid

    synthesis Golgi bodysorting and shipping proteins

    Lysosomes/Peroxisomestransporting or

    storing a variety of substance

    Mitochondriaproducing many ATP molecules

    in highly efficient fashion

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    The Nucleus

    Control center of

    eukaryotic cells

    The organelle thatphysically separates

    DNA from cytoplasmic

    machinery

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    Components of Nucleus

    nuclear envelope

    nucleoplasm

    nucleolus

    chromatin

    Figure 4.11b

    Page 62

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    Components of the Nucleus

    Nuclear Envelopepore riddled double

    membrane system that selectively controls

    the passage of various substances intoand out of the nucleus

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    Nuclear Envelope

    Two outer membranes (lipid bilayers)

    Innermost surface has DNA attachment sites

    Nuclear pore bilayer facing cytoplasm Nuclear envelope

    bilayer facingnucleoplasm

    Figure 4.12bPa e 63

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    Components of the Nucleus

    Nucleoplasmfluid interior portion of the

    nucleus

    NucleolusConstruction site wherecertain RNAs and proteins are combined

    to make ribosomal subunits

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    ChromatinTotal collection of all DNA

    molecules and their associated proteins in

    the nucleus ChromosomeOne DNA molecule and

    many proteins that are intimately

    associated with it

    Components of the Nucleus

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    Series of functionally connected

    organelles in which lipids are assembled

    and new polypeptide chains are modified. Products are sorted and shipped to

    different destination

    Endomembrane System

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    Components of Endomembrane

    System

    Endoplasmic Reticulum

    Golgi Bodies

    Vesicles

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    Endoplasmic Reticulum

    In animal cells, continuous with nuclear

    membrane

    Extends throughout cytoplasm

    Two regions - rough and smooth

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    Endoplasmic Reticulum and the Ribosomes: protein

    production machine

    Endoplasmic Reticulum (ER)

    source: http://cellbio.utmb.edu/cellbio/ribosome.htm

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    Golgi Body

    Puts finishing touches on proteins and

    lipids that arrive from ER

    Packages finished material for shipment tofinal destinations

    Material arrives and leaves in vesicles

    buddingvesicle

    Figure 4.15Pa e 65

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    Vesicles

    Membranous sacs that move through

    cytoplasm

    Lysosomes

    Organelle of intracellular digestion

    Peroxisomes

    Breaks down fatty acids and amino acids

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    Lysosomes Rich in digestive enzymes (that work at low

    pH)

    Digest bacteria that invade a cell

    Recycling of membrane components

    Repair damage to plasma membrane

    Get rid of toxic substances Many in the liver

    Peroxisomes

    lysosome

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    Mitochondrial Origins

    Mitochondria resemble bacteria

    Have own DNA, ribosomes

    Divide on their own

    May have evolved from ancient bacteriathat were engulfed but not digested

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    Mitochondria

    Contain their own genome

    (distinct from nuclear

    genome)

    Self-replicating

    Critical role in generation of

    energy (called ATP):

    -

    Glycolysis (without oxygenuse)

    - Krebs cycle (in presence of

    oxygen)

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    Non-membranous Structures and

    their Functions RibosomesAssembling polypeptide

    chains

    CytoskeletonImparting overall shapeand internal organization to the cell;

    locomotion

    MicrotubulesMicrofilaments

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    Cytoskeleton

    Reinforce, organize, and move internal cell

    parts

    MicrofilamentsTwo polypeptide chains of actin monomers

    Structural support

    MicrotubulesProteins cylinders (tubulin monomers)

    move cell interior

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    Cytoskeleton

    Intermediate filaments

    Help strengthen and maintain the shape of

    cells and cell parts

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    The cytoskeleton: a cell's

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    The cytoskeleton: a cell sscaffold

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    Specialized Plant Organelles

    Chloroplasts

    Chromoplasts

    Amyloplasts Central Vacuole

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    Chloroplast

    Use sunlight energy to drive the formation

    of ATP and NADPH.

    Used to assemble sugars and some otherorganic compounds

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    Chloroplast

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    Thylakoid membrane

    The first stage of photosynthesis starts

    where many light-trapping pigments,

    enzymes and other proteins areembedded

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    Plastids

    Chromoplast

    - Lacks chlorophyll, but they have an

    abundance in carotenoids

    Amyloplast

    - Lacks pigments, often they store starch

    grains and are abundant in cells of stems,potato tubers, and seeds

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    Central Vacuole

    Fluid-filled organelle surrounded by singlemembrane

    Stores amino acids, sugars, ions and toxic

    wastes Helps the cell grow

    It expands during growth

    Blue or purple pigments stored in the central

    vacuoles are responsible for the colors of theflower

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    How Do Cells Move?

    Cilia

    Flagella

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    Cell Surface Specializations

    Cell wall

    - structural component that wraps

    continuously around the plasmamembrane

    - it is porous

    Cell Junction- where a cell sends and receives signalsand materials, and where it recognizesitself to cells of the same type

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    Plant Cell Walls

    Primary cell wall

    Secondary cell wall

    (3 layers)

    Thin and pliable

    Permits the cell to continue to

    enlarge under the pressure of

    incoming water

    reinforces cell shape

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    Animal Cell Junctions

    tight

    junctionsadhering

    junctiongap

    junction

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    Cell Communication

    - one cell signals another to change its

    activities

    Cell Surface Specializations