日獣パンフBW.indd 1 2007/01/11 11:45:07...Associate Professor AMAO Hiromi Assistant Professor KAWASUMI Koh 日獣パンフBW.indd 9 2007/01/11 11:45:09 NIPPON VETERINARY AND LIFE

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NIPPON VETERINARY AND LIFE SCIENCE UNIVERSITYResearch Interests of Academic Staff 2006

NIPPON VETERINARY AND

LIFE SCIENCE UNIVERSITY

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日本獣医生命科学大学　研究者一覧

平成 18 年度

HISTORY OF NIPPON VETERINARY AND LIFE SCIENCE UNIVERSITY

1881 Established as a private veterinary school, Tokyo.

1949 Raised to the status of College, according to

Japan’s new education system, changing the name to

Nippon Veterinary and Zoo technical College .

1952 Merged with Nippon Medical School.

1967 Established the Department of Food Science and

Technology.

1982 Established a six-year program for students in the

Department of Veterinary Medicine.

1991 Changed the name to Nippon Veterinary and

Animal Science University.

2003 Established the Faculty of Veterinary Science and

the Faculty of Applied Life Science.

2005 Established the Department of Veterinary Nursing.

2006 Changed the name to Nippon Veterinary and Life

Science University.

We cerebrate the 125th anniversary in 2006

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MOU

2001 Northeast Agricultural University , China

2003 Kasetsart University, Thailand

2003 Khon Kaen University, Thailand

2003 Chonnam National University, South Korea

2004 Hue University of Agriculture and Forestry, Vietnam

2005 The University of Queensland, Australia

2006　 Chiang Mai University, Thailand

SYNOPSIS

The number of students about 1,300

The number of teaching staff about 130

The number of alumni about 14,000

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President of Nippon Veterinary Life Sience University　　　

IKEMOTO Shigenori

Faculty of Veterinary Science

School of Veterinary Medicine

Laboratory of Veterinary Anatomy

Professor AMASAKI Hajime

Associate Professor KAMIYA Shinji

Research Associate SOETA Satoshi

Laboratory of Veterinary Physiology

Professor SUZUKI Katsushi

Associate Professor SUZUKI Hiroetsu

Laboratory of Veterinary Biochemistry

Professor ARAI Toshiro

Assistant Professor SASAKI Noriyasu

Laboratory of Veterinary Pharmacology

Professor SHIMIZU Kazumasa

Assistant Professor KANEDA Takeharu

Laboratory of Veterinary Pathology

Professor TAKAHASHI Kimimasa

Assistant Professor OHKUSU-Tsukada,Kozo

Research Associate MICHISHITA Masaki

Laboratory of Veterinary Microbiology

Professor SAWADA Takuo

Associate Professor KATAOKA Yasushi

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Laboratory of Veterinary Parasitology

Professor IMAI Soichi

Associate Professor IKE Kazunori

Research Associate MORITA Tatsushi

Laboratory of Veterinary Internal Medicine

Professor HIROSE Hisashi

Associate Professor KOYAMA Hidekazu

Associate Professor TAKEMURA Naoyuki

Research Associate MIZUTANI Hisashi

Laboratory of Veterinary Surgery

Professor TAGAWA Masahiro

Associate Professor HARA Yasushi

Research Associate NEZU Yoshinori

Research Associate YOGO Takuya

Research Associate HARADA Yasuji

Laboratory of Veterinary Radiology

Professor ORIMA Hiromitsu

Associate Professor FUJITA Michio

Research Associate HASEGAWA Daisuke

Laboratory of Veterinary Reproduction

Professor TSUTSUI Toshihiko

Professor KAWAKAMI Eiichi

Assistant Professor HORI Tatsuya

Laboratory of Veterinary Clinical Pathology

Associate Professor WASHIZU Tsukimi

Assistant Professor BONKOBARA Makoto

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Laboratory of Veterinary Hygiene

Professor KAMATA Shin-ichi

Professor KAKIICHI Norihide

Research Associate TANAKA Yoshikazu

Laboratory of Veterinary Public Health

Professor UEDA Fukiko

Research Associate OCHIAI Yoshitsugu

Laboratory of Comparative and Behavioral Medicine

Professor SAITO Toru

Assistant Professor YOKOSUKA Makoto

Laboratory of Fish Diseases

Professor HATAI Kishio

Associate Professor WADA Shinpei

Assistant Professor KURATA Osamu

Laboratory of Wildlife Medicine

Associate Professor NAKAGAKI Kazuhide

Associate Professor HAYAMA Shinichi

Laboratory of Comparative Cellular Bilogy

Professor HARADA Takahiko

Associate Professor TSUCHIDA Shuichi

Research Associate HATAKEYAMA Hitoshi

Laboratory of Structural Bioinformatics

Associate Professor TAZAKI Hiroyuki

Research Associate KATAYAMA Kinya

Laboratory of Comparative Developmental Psychology

Professor KAKINUMA Miki

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School of Veterinary Nursing and Technology

Department of Basic Science

Professor FUKUSHO Akio

Professor MUKOYAMA Harutaka

Associate Professor HAKAMATA Yoji

Associate Professor OMI Toshinori

Assistant Professor YOSHIDA Takaharu

Assistant Professor AOKI Hiroshi

Department of Applied Science

Professor OGAWA Takashi

Associate Professor KAJIGAYA Hiroshi

Assistant Professor ASADA Tadatoshi

Assistant Professor YUMOTO Norio

Assistant Professor KOBAYASHI-Mochizuki Mariko

Assistant Professor YAMAMOTO Toshiaki

Department of Veterinary Nursing

Professor MURAMATSU Umetaro

Professor SAKO Toshinori

Assistant Professor ISHIOKA Katsumi

Assistant Professor MAKINO Yuki

Laboratory of Veterinary Medical Teaching Hospital

Associate professor WASHIZU Makoto

Faculty of Applied Life Science

School of Animal Science

Laboratory of Animal Systems Management

Associate Professor NISHITANI Jiro

Associate Professor OZAWA Takeyuki

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Laboratory of Nature Management and AgriFood Economics

Professor MATSUKI Yoichi

Associate Professor NAGAMATSU Miki

Laboratory of Animal Nutrition

Professor KIMURA Nobuhiro

Assistant Professor TOKITA Norio

Research Associate NADE Toshihiro

Laboratory of Animal Physiology

Professor TANAKA Minoru

Assistant Professor TSUSHIMA Nobumichi

Laboratory of Breeding & Genetics

Assistant Professor YOSHIDA Tatsuyuki

Research Associate FURUTA Hiroki

Laboratory of Animal Reproduction

Professor TOMOGANE Hiroshi

Research Associate OKADA Konosuke

Laboratory of Applied Animal Biochemistry

Professor SUGAWARA Moriyuki

Associate Professor OHTA Yoshiyuki

Laboratory of Laboratory Animal Science

Associate Professor AMAO Hiromi

Assistant Professor KAWASUMI Koh

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Laboratory of English

Associate Professor FUJIYOSHI Norio

Laboratory of Exercise Science

Associate Professor HAMABE Hirokazu

School of Food Science and Technology

Laboratory of Functional Food Culture

Professor ITO Osamu

Laboratory of Animal Products Science and Technology

Professor AKUZAWA Ryozo

Associate Professor ODAKE Sachiko

Research Associate MIURA Takayuki

Laboratory of Food Technology

Professor KANEKO Kentaro

Reserach Associate YAGI Shohei

Laboratory of Food Chemistry

Associate Professor MATSUISHI Masanori

Research Associate MIGITA Koshiro

Laboratory of Food Hygiene

Associate Professor FUJISAWA Tomohiko

Research Associate OHASHI Yuji

Laboratory of Agricultural Foods

Professor ASO Keiichi

Research Associate KANEYAMA-Narai Asako

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Laboratory of Food Biotechnology

Associate Professor GOTO Kimihiko

Assistant Professor HARA Hiroyoshi

Laboratory of Food Economics

Professor SASAKI Teruo

Laboratory of Physics

Professor INAGAKI Toshio

Division of the English language

Assistant Professor SHISHIDO Makoto

Assistant Professor SAITO Kenichi

Fuji Animal Research Farm

Associate Professor YOSHIMURA Itaru

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President of Nippon Veterinary and Life Science University

IKEMOTO, Shigenori　池本卯典,　VMD, MD, PhD

My own Research has mainly involved much genetic markers in animal and human

blood cell, and personal identification of forensic materials.

Since the Meiji Era, Japanese veterinary medicine have been established and

operated under one mandate, and that is to propagate foreign veterinary medicine

in Japan.

In anticipation of drastic changes in the research environment and to promoter

the advancement of 21st century veterinary medicine, Nippon Veterinary and Life

Science University (NVLU) was organizationally restructured 2006 April. NVLU now

consists of two main research department of high veterinary technology research

center and advanced veterinary clinical research and teaching hospital.

We would like to continue our full hearted efforts in functioning not only in

personnel development but also as the central research institution for advanced

veterinary medical sciences in fields.

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Prof. AKUZAWA, Ryozo　阿久澤良造,　PhD　

I have several ongoing projects in the general area of enzymes in milk and

cheese ripening, which fall into 2 main projects:

1. Isolation and characterization of enzymes (proteinases, peptidases,

phosphatases, transglutaminases, catalases) from bovine milk and cheese-related

bacteria (Lactococcus, Lactobacillus, Penicillium).

2. Isolation and characterization of peptidases from various cheese varieties

(Cheddar, Gouda, Blue, Camembert).

Associate Prof. AMAO, Hiromi　天尾弘実,　BASc, PhD　

My research and teaching interests include subjects in the field of Laboratory

Animal Science. I have a special interest in infectious diseases of small

laboratory animals, and have focused particularly on murine corynebacteriosis

in the mouse, rat and Syrian hamster. In addition , I am also involved in a

study of the correlation between the expression of superoxide dismutase (SOD)

and intestinal flora using transgenic mice overexpressing the human Cu/Zn SOD

(hSOD-1 Tg mice) and germ free mice. Furthermore, I am involved in the study

of the sensitivity of B cells to oxygen stress in a model of insulin- dependent

diabetes mellitus induced by alloxan prepared using hSOD-1 Tg mice.

Prof. AMASAKI, Hajime　尼崎　肇,　DVM, MS, PhD　

My research target is the developmental morphology of the molecular based

digestive system; i.e., the pattern formational control study of palatal

rugae, the differential control study of pancreatic endocrine cell and of the

functional control of intestinal immune cell etc, and also the comparative

morphological study of digestive organs of the wild animals. It is hoped that

my research will be useful for the development of medical care and artificial

internal organ.

Assistant Prof. AOKI, Hiroshi,　青木博史,　BVSc, DVM, PhD　

My main areas of research interest are animal infectious viral diseases,

especially caused by RNA viruses. I had conducted biological, genetical,

serological and diagnostic studies of pestiviruses (classical swine fever virus

and bovine viral diarrhea virus) and rabies virus. Ongoing studies include

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the mechanisms underlying cytopathogenicity, interference phenomenon and END

phenomenon of bovine viral diarrhea virus. I had also started studies on

pathogenic viruses isolated from companion animals. The major objective of

my work is to control and prevention of animal viral infections based on the

results of basic research obtained by use of the biology, molecular biology and

gene technology.

Prof. ARAI, Toshiro　新井敏郎,　DVM, PhD　

I graduated from Nippon Veterinary and Animal Science University in 1981,

and have always had a strong interest in research and teaching. My broad

research and teaching interest include: biochemistry, nutrition metabolism and

endocrinology. My research focuses mostly on the onset mechanism of metabolic

disorders such as obesity, diabetes mellitus and tumor in animals. My current

research project is concerned with the development of diagnosis and prophylaxis

for metabolic disorders using genome, proteome and metabolome analyses. I am the

chief investigator of “High-Tech Research Center Project” (2004 to 2008) and

“Science Frontier Promotion Project” (2005 to 2009): matching fund subsidy from

Ministry of Education, Culture, Sports, Science and Technology of Japan.

Assistant Prof. ASADA, Tadatoshi　浅田忠利,　DVM　

My main research interests lie in the treatment of fish diseases using wood

vinegar and in the effectiveness of companion animals, human diabetes mellitus

or allergic disorder. I am also researching the development in new forage making

use of low or yet-to-be-used resources.

Furthermore, I am making a joint study of low-cost technology for composting

by putting sawdust and materials for environmental pollution control to use in

cooperation with a certain external institute.

Prof. ASO, Keiichi　麻生　慶一,　PhD　

The main research subjects of our division “Agricultural Food” are focused

on food biochemistry and food enzymology of cereals, vegetables, fruits and

other agricultural food materials. At present, I am particularly interested in

the relationship between structure and function of plant aminopeptidases from

the viewpoint of enzymology in connection with flavor development and quality

control of agricultural foods, and also in the fundamental studies and practical

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applications of protease-mediated syntheses of functional peptides with

desirable taste and biological significance in terms of enzyme biotechnology. My

current areas in teaching programs for undergraduate and postgraduate students

include introductory food sciences, biochemistry, agricultural food science,

agricultural food resources and advanced food chemistry.

Assistant Prof.BONKOBARA, Makoto　盆子原誠,　DVM, PhD　

My basic research interests are dendritic cell-mediated immunity, gene-

based immunomoduration, and keratynocyte biology. In the clinical research,

I have interesting in the companion animal oncology including immunotherapy,

kinase-targeted therapies using small molecules, and development of molecular

diagnosis.

Associate Prof. FUJISAWA, Tomohiko,　藤澤倫彦　PhD　

My research interests include the fields of food microbiology and intestinal

microbiology. My current areas of food microbiology are taxonomy of food

bacteria and evaluation of selective medium for isolation of harmful bacteria

including Escherichia coli O157:H7, Salmonella and Clostridium perfringens from

various foods such as raw vegetables, spices, herbs and commercially available

curry roux. In the field of intestinal microbiology, I am particularly interested

in the effects of probiotics and prebiotics on the composition and metabolic

activity of human fecal flora, influence of bile salts on the activity of cancer-

associated bacterial enzymes such as β -glucuronidase and β -glucosidase, and

taxonomy of intestinal anaerobic bacteria.

Associate Prof.FUJITA, Michio　藤田道郎,　PhD　

Small Animal Clinical Oncology (Veterinary Radiology Oncology、Internal

Medicine of Veterinary Oncology)

Diagnostic Radiology, Computed tomography and Magnetic resonance imaging of

the Dog and Cat

Associate Prof. FUJIYOSHI, Norio　藤吉憲生,　BA, MA　

I graduated from Waseda University in 1970. My scientific concern has been

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linguistics in general; especially transformational generative grammar, Japanese

and English syntax and the formation of linguistic units as human knowledge.

Prof. FUKUSHO, Akio　福所秋雄,　BVSc, MSc, DVM, PhD　

Major research interests are animal infectious viral diseases caused by

RNA viruses, especially, pestiviruses such as classical swine fever virus and

dsRNA viruses such as rotavirus and orbiviruses. Up to now, the investigation

concerning to interaction between virus and cultured cells was done by using the

biological and gene technology. Consequently, some unique assay methods (Reverse

plaque formation method, a new virus detection method and so on) were developed

for accurate diagnosis.

At the present, the major focus is on the development of transgenic pet

animals resistant to viral diseases using the phenomenon based on the Intrinsic

Interference caused by a certain pestivirus infection.

Supposing you come to get interested in my research, please search PubMed on

the Internet for "fukusho a" as an author.

Research Associate FURUTA, Hiroki　古田洋樹,　PhD　　

Hiroki graduated from Kyushu University in 1998 with a Master of Agrictural

Science and 2001 with PhD. His experiment topic was designed to produce

germ line chimeric chicken by transferring primordial germ cells (PGCs) of

chicken embryos. The introduction of exogenous genes was conducted to PGCs of

the embryos with lipofection or electroporation methods, whether transgenic

offspring may be produced via germline chimeric chicken!?

Associate Prof. GOTO, Kimihiko　後藤公彦,　PhD　

The research interests of Laboratory of Food Biotechnology include:

biotechnological alternation of the quality of meat (the increase of

polyunsaturated fatty acids contents), improvement of the ability of digestion

in livestock by gene transferring methods (degradation of cellulose in the small

intestine of bovine by cellulase gene transferring in the cell), production of

new functional materials from the waste (chitin, chitosan, scales of fishes, etc)

produced during food processing and the polymers made by microorganisms (poly

g-glutamic acid, etc) using new enzymes from Actinomycetes, the origin of life

in the primordial earth (especially the origin of cell membrane), phylogenic

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study of microorganisms by molecular biological methods.

Associate Prof. HAKAMATA, Yoji　袴田陽二,　DVM, PhD　

Dr. Hakamata’s research interests concern comparative medicine and

reproductive biology. Research projects include the development of more efficient

research models for veterinary and human medicine using biotechnology (e.g.

models utilizing a transgenic and knock-out animal). He is also interested in

investigations of organ regeneration using organ stem cells to cure intractable

disease, as well as the cryopreservation of stem cells and tissue for clinical

usage.

Associate Prof. HAMABE, Hirokazu　濵部浩一,　PhD　

My laboratory does the study that made exercise science and health science of

an animal a theme. I began a study of movement analysis of an animal in 2005.

I photograph it with by 2 dimensions of movement of an animal or 3 dimensions

and work and analyze it. I examine mechanism and a characteristic of exercise

ability by this and study maintenance improvement of exercise ability. An

education domain in a department includes sports science (a diving, a ski, golf,

fitness, tennis, and basketball), health science, a human animal-related idea,

and a graduation thesis.

Assistant Prof.HARA, Hiroyoshi　原宏佳, PhD

The research subjects of division of Food Biotechnology are improvement of

the ability of digestion in livestock by gene transferring methods and sarcing

for bacteriocin of Lactic Acid Bacteria and ther applications.

Associate Prof. HARA, Yasushi　原　康,　DVM, PhD

(1) Diagnosis & surgical treatment for intracanial tumors in the dog.

Now, I have interests in pathophysiology, diagnosis, and surgical therapy for

canine Cushing disease associated with ACTH-producing pituitary tumors.

(2) Diagnosis & surgical treatment for spinal diseases in the dog.

Now, I have interests in the degenerative mechanism of the nucleus puloposus

of discs in the chondrodystrophoid dog.

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(3) Diagnosis & surgical treatment for joint disease in the dog.

Now, I have interests in two problems.

One of them is clinical efficacy of functionally stabilizing techniquesfor the

dog with cranial cruciate ligament rupture.

Another interest is biomechanics of the stifle joint in the dog.

(4) Growth factors of the bone & bone healing.

Now, I have interests in regenerative potential of basic fibroblast growth

factor (bFGF) for bone fracture and nonunion fracture.

Prof. HARADA, Takahiko 原田隆彦,　DVM, PhD　

We study usefulness of medaka as a substitute laboratory animal of a rodent.

Research Associate HARADA, Yasuji　原田恭治,　DVM, PhD　

My specific field is veterinary orthopedics, biomechanics and tissue

regeneration. When I was a post-graduate student, I studied the mechanical

influence to stimulate the articular cartilage regeneration. Now I am interested

in the regenerative therapy and its clinical use for veterinary patient. As a

cell source of regenerative therapy, mesenchymal stem cell has been focused on

their ability to differentiate multipotentially into varied types of cells.

Mesenchymal stem cells, isolated from bone marrow or adipose tissue in

animals, are examined their character of proliferation or differentiation

(osteogenic, chondrogenic, adipogenic). These research data will provide great

benefits for bone regeneration, cartilage regeneration, spinal cord regeneration,

etc. in veterinary surgery.

Research Associate HASEGAWA, Daisuke　長谷川大輔,　DVM, PhD　

My research interests include neurology, neurosurgery, neuroscience and

diagnostic imaging using MRI and/or CT. Especially I study canine and feline

epilepsy as my life work.

Prof. HATAI, Kishio　畑井喜司雄,　PhD　

I have broad research interests in diseases of aquatic animals. Specific areas

of interest are in fungal diseases including cultured marine and freshwater

fishes, tropical fishes and crustaceans. I am particularly interested in fungal

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diseases due to lower fungi of aquatic animals. [email protected]

Research Associate HATAKEYAMA, Hitoshi 畠山　仁,　ME

My broad research and teaching interests include: biology, pathology,

ethology, gerontology and animal psychology. My research focuses mostly on the

biology of medaka fish (the measurement of telomere length, the screening for the

reproductive toxicity of chemicals and the examining sexual selection).

Associate Prof. HAYAMA, Shinichi,　羽山伸一,　PhD　

I am interested in wildlife issues between Japanese peoples and wild animals.

My research interests include: wildlife management for large mammals especially

Japanese monkeys, wildlife policy and low, problem of invasive alien species,

reintroduction of endangered species. My aim is to solve these problems for

conservation of biodiversity by using multiple methods, for example, field

research, education, public participations.

Prof. HIROSE, Hisashi　廣瀬　昶,　DVM, PhD　

My research and teaching interests include: a diagnosis and a therapy of

a cardiac disease in an animal, a therapy for arrhythmia in an animal and

evaluation of cardiac function.

Sustained tachycardia decreases cardiac function. Tachycardia causes

myocardial remodeling and a heart develops cardiac failure.

A point of interest in my study is prevention of cardiac failure by

tachycardia

Assistant Prof. HORI, Tatsuya　堀　達也,　DVM, PhD　

My research interests include canine and feline reproductive physiology and

reproductive assisted technology (ex. artificial insemination, embryo transfer,

cryopreservation of sperm and ovum and in vitro fertilization). My research aims

at applying the endangered Canidae and Felidae. My current research interests

include mechanism that maintains luteal function in bitch, mechanism that starts

estrus in bitch and cryopreservation of canine and feline epididymal sperm.

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Associate Prof. IKE, Kazunori　池　和憲,　DVM, PhD　

Research interests of mine include the fields of veterinary parasitology and

immunology.

I investigate the protective immunity of model animals for Neospora caninum as

intracellular protozoon and Babesia microti or Babesia rodhaini as hemocytozoon.

Especially, my current research interests are vaccine ajuvants as plant extracts

or others.

Prof. IMAI, Soichi　今井壯一,　BSc, MSc, PhD

Veterinary parasitology is my broad research and teaching field, and my

research interest is particularly focused on the taxonomy, morphology and

biogeography of the ciliate protozoa inhabiting the gastrointestinal tracts of

large herbivorous mammals including so-called rumen protozoa. The data obtained

are used for the discussion on the evolution both of the ciliates and their

hosts. The other interests are various aspects of the biology of arthropods such

as fleas and ticks, and fish parasites.

Prof. INAGAKI, Toshio　稲垣敏夫,　PhD

I am interested in theoretical physics. My current interest is to construct

the formalism of a photon quantum-mechanically. As for a free photon, the

Schrödinger equation could be derived from the Maxwell equation of the

electromagnetic fields in vacuum and the physical meaning of its wave function

as the probability amplitude is guaranteed by the concept of the coarse-

grained representation. It also became clear that the behavior of a photon in

a macroscopic refractive medium is successfully described under the coarse-

grained representation. My present study is devoted to the quantum-mechanical

description of a photon interacting with the true charges and currents.

Assistant Prof. ISHIOKA, Katsumi　石岡克己,　DVM, PhD　

My research interests include internal medicine, biochemistry and molecular

biology of companion animals. Focus is on the metabolic diseases, such as

obesity, diabetes and other endocrinological disorders. I would like to reveal

metabolic mechanisms which are different from human beings, and solve the

clinical problems in dogs and cats. Using gene analyses and ELISA methods,

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I have studied adipocytokines (cytokines produced by adipocytes), such as

leptin and adiponectin. Development of a novel obese-treatment method is also

concerned, especially, mitochondrial uncoupling proteins are focusing target

molecules. Now then, I am very interested in international research cooperation,

and any contact will be welcome.

Prof. ITO, Osamu　伊藤　整,　PhD　

I am in the midst of searching for physiologically functional factors

contained in cow milk to research the effects on living bodies. An

immunoenhancing factor, among them, closely relates to life style diseases,

including cancer, and is thus one of interesting research subjects. A component

separated from the milk and refined was used to act on the immune T-cell to

analyze the rate of cellular proliferation and cytokine released from the

T-cell, and the effective result has been obtained.

It is my desire to elucidate biological mechanism in animal tests from now

on, including specification of regions to be affected. Also, it is my desire

in the future to extract functional factors from food to thereby contribute to

development of food products for nursing-care and medical treatment.

Associate Prof. KAJIGAYA, Hiroshi　梶ヶ谷　博,　DVM, PhD　

I am interested in the cause of death of wild birds.　Generally when an

animal which did not show any symptoms died suddenly, morphological change is

not found on the dead body. Perhaps the reason is because the bird died before

a morphological change happens in the bird. In an oil spill, we can see the

similar situation. I made clear with a physical simulation that adhesion of

spilled oil to feathers decrease body temperature of a polluted bird. This main

cause is because a down feather layer as a warm temperature barrier is destroyed

by oil-adhesion or oil-penetration. My next aim is to clarify the biophysical

role of a contour feather of a waterfowl.

Prof. KAKIICHI , Norihide　柿市徳英,　BVs, PhD　

My research interests include the fields of the environmental hygiene for

animal production. The research contents: Development of technique for removal

of nitrogen and phosphorus from animal wastewater, effects of agricultural

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chemicals free-living ciliated protozoa, search of biodegradable bacteria of

insecticides, preying of pathogenic bacteria by free-living ciliated protozoa,

and biological control technique of odor gas from composting of animal wastes.

Prof. KAKINUMA, Miki　柿沼美紀,　PhD　

Comparative developmental psychology is my main interest. By comparing

developmental process of social behavior of different species such as chimpanzee

and dogs and of cultures like US, China and Japan, I attempt to build a model of

the human social cognitive development. As a psychologist, I am also interested

on the human-animal interaction, particularly of the owner and the pets.

Prof. KAMATA, Shin-ichi　鎌田信一,　DVM, MSc, PhD　

The main focus of research is on the prevention of bacterial infection

in animal(cattle, canine, and feline). Especially, on the epidemiology

and microbiology of dairy cattle on commercial farm pathogen, including:

enterohorragic E.coli including E.coli 0157:H7; isolated strains of

Staphylococcus aureus of skin and uro infection of small animal (canine and

feline), including antimicrobial agents resistance (newquinolone, other

antibiotics), and Dr. Kamata particularly interested in the joint development

of the animal antimicrobial agents for the prevention of infectious disease of

animal health.

A second interest involovves the application of immunochemistrty to diagnose

of the infectious disease (improvement of the diagnose with the early time and

easy method).

Associate Prof. KAMIYA, Shinji　神谷新司,　DVM, MVM, PhD　

My research interests include the fields of veterinary anatomy and comparative

pathology. My research focuses mostly on the age-related morphological and

histochemical changes in the central nervous system of various animal species.

I am particularly intereted in the inclusion bodies, especially polyglucosan

bodies, that occur in neuronal and glial cells with increasing age in the animal

brain.

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Assistant Prof. KANEDA, Takeharu　金田剛治,　DVM, PhD　

My research interests include veterinary pharmacology. Recently, I am

interested in effects of phosphodiesterase inhibitors on contractility of

various smooth muscles.

Prof. KANEKO, Kentaro　金子憲太郎,　PhD　

My broad research interests include the field of development of food processing

technique: vegetables, soy bean seeds and garlic. My research focuses mostly to

research wider uses to vegetables, especially blade vegetables, root crops and

othes of the low temperature steam heating process.

Research Associate KANEYAMA-Narai, Asako 金山（奈良井）朝子,　PhD　

The main research subjects of our division “Agricultural Food” are

focused on food biochemistry and food enzymology of cereals, vegetables,

fruits and other agricultural food materials. At present, I am involved in

projects exploring the relationship between structure and function of several

aminopeptidases derived from plants by isolation, purification, characterization

and amino acid sequence analysis of those enzymes, and exploring the mechanism

of protease-catalyzed peptide synthetic reactions for preparing functional

peptides. My current interest is also focused on the development of functional

foods using materials containing ingredients good for the health such as

fructooligosaccharide containing Yacon (Andean tubers).

Associate Prof. KATAOKA, Yasushi　片岡　康,　DVM, MS, PhD　

My research interests include etiological, genetical and immunological

characterization of pathogenic bacteria isolated from animals and humans, and

application of those characteristics for epidemiological analysis, diagnosis,

prevention and treatment of infectious diseases. I have been studing mainly

with Streptococcus suis infection in pigs and bacterial infections in companion

animals.

My area of undergraduate teaching include veterinary bacteriology, bacterial

infectious diseases in animals and bacterial zoonoses, and basic computer

applications.

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Research Associate KATAYAMA, Kinya　片山欣哉,　BSc, PhD　

My current research interests are secondary metabolite biosynthesis in

microorganisms, gene cloning and expression, enzyme reaction mechanisms,

combinatorial biosynthesis, and natural product drug discovery. I am

particularly interested in combinatorial biosynthesis of lantibiotics, peptide-

derived antimicrobial agents, produced by Gram-positive bacteria.

Prof. KAWAKAMI, Eiichi　河上栄一,　DVM, PhD　

My research interests include the field of veterinary reproduction of male

dogs. Especially I am doing study on sperm capacitation and treatments of

testicular diseases (cryptorchidism, spermatogenic dysfunction, astheno-

teratozoospermia, and tumor) and prostatic diseases (benign hypertrophy, cysts,

inflamation, abscess, and adenocarcinoma) in dogs.

Assistant Prof. KAWASUMI, Koh　川角　浩,　DVM, PhD　

My research and teaching interests include microbiology and clinical

immunology. I have investigated to detect the early subclinical stage

of Staphylococcus aureus (Sa)-induced bovine mastitis using the milk

chemiluninescence(CL) assay. Compared to somatic cell counting,and bacterial

examinationtest, I believe that the milk CL method enables to detect theinitial

stage of mastitis more earlier. Recently, my attention was focused on the

antibacterial effect of Curcuma Aromatica Salisb on Sa. I would like to develop

Curcuma treatments as alternatives that can be replaced with antibiotics for the

bovine mastitis.

Prof. KIMURA, Nobuhiro　木村信熙,　BSc, PhD, PE　

I have been transferred to this university from private firm’s research

institute. My major research area is animal nutrition and I have interest in

ruminant nutrition especially in feed and feeding of fattening beef cattle.

I am particularly interested in the relationship among beef quality, energy

metabolism and nutritional disorders affected by nutritional environments. In

these years I conduct beef cattle fattening trials at the university institute

and industrial farms in Japan and Korea. I also have interest in comparative

animal nutritional physiology such comparison as herbivore and carnivore in

their energy metabolism.

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Assistant Prof. KOBAYASHI-Mochizuki, Mariko 小林（望月）眞理子 ,　DVM, PhD

My current research interests include;

1) Epidemiological study of heavy metal contamination of wild birds

2) Effects of toxic metals for several cell lines, reproduction of birds, and

experimental animals

Associate Prof. KOYAMA,Hidekazu　小山秀一,　DVM, PhD　

My research and teaching interests include: veterinary internal medicine and

ultrasound diagnosis. My current research is pathophysiological elucidation

and establishment of a therapy of chronic heart failure and arrhythmic

analysis and therapy in dogs and cats. In these research, cardiac function

is mainly evaluated by echocardiography, electrocardiography and Holter

electrocardiography. In abdominal ultrasound diagnosis, I research ultrasonic

diagnostics criteria in various organ.

Assistant Prof. KURATA, Osamu　倉田　修,　PhD　

My research field is fish immunology. Especially I am interested in innate

cellular immune response and development of the responses in fish. My recent

study is to solve mechanisms of an encapsulation system by fish leukocytes

against the pathogens. The encapsulation response in fish also looks an important

defense system to protect from invading pathogens. I established an in vitro

model for study of encapsulation by leukocytes and I am trying to find immune

molecules, including cell-surface receptors that recognize pathogens, cytokines

and chemokines that regulate to make the encapsulation. I also study about

the development of encapsulation response in fry to understand the process of

functional maturation in immune cells.

Assistant Prof. MAKINO, Yuki　牧野ゆき,　DVM, LLM　

My areas of general research are civil law, veterinary/medical law and

veterinary/medical ethics. These include various matters concerning laws and

ethics, such as contract, tort, informed consent, decision making and autonomy,

veterinary/medical malpractice and animal welfare.

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Associate Prof. MATSUISHI, Masanori　松石昌典,　PhD　

My main research interests include the fields of food chemistry and food

biochemistry. I am particularly interested in the cause of palatability of

various foods, especially meat. My current research project is focused on

the mechanism of generation of preferable sweet and fatty aroma (Wagyu beef

aroma), which is specific to highly-marbled Wagyu beef and is a main reason why

Japanese people prefer Wagyu beef to imported beef. Some lactones, aldehydes and

alcohols have already been clarified to contribute to Wagyu beef aroma, so that

the research on the enzymatic and/or non-enzymatic mechanism of generation of

these compounds is going on.

Prof. MATSUKI, Yoichi 　松木洋一,　PhD　

(1) AgriFood Supply Chain Development in Japan and EU

(2) Multifunctionality of Agriculture and Rural Planning

(3) Agri-environmental Policy in EU

(4) Organic Livestock Industry

(5) Urban Agriculture

Research Associate MICHISHITA, Masaki　道下正貴,　DVM, PhD　

My current research focuses on understanding the molecular and cellular

function of cancer cells based on the techniques of morphology, molecular

biology and gene targeting. One fundamental aim of my research is to identify

genes and molecular pathways involved in the pathogenesis of malignant tumors,

including canine and feline mammary glands. I will try to obtain microarray-

based gene expression profiles in spontaneous canine mammary carcinoma. I

believe that my research will contribute to the development of new strategies

for the diagnosis, therapy and prevention.

Research Associate MIGITA, Koshiro　右田光史郎,　 PhD

I have researched about Cl--activated aminopeptidase which seemed to

contribute to the improvement of meat taste during postmortem aging. I purified

and investigated certain properties of the enzyme. Furthermore, I succeed in

molecular cloning and expression of the enzyme. My current interests include the

mechanism of generation of Wagyu beef aroma. Wagyu beef aroma is odor peculiar

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to Wagyu beef, and Japanese like a Wagyu beef for the reason.

Research Associate MIURA, Takayuki　三浦孝之,　PhD　

My area of investigations is livestock food products, especially, it is

interested in dairy foods. For example, the mechanism of ripening cheese, that

traditional dairy food behavior is examined by using enzymology and biochemical

methods.

Research Associate MIZUTANI, Hisashi　水谷　尚,　DVM, PhD　

Research Associate MORITA, Tatsushi　森田達志,　DVM, PhD　

Parasitology, especially cat fleas, scabies mites and liver flukes.

Identification of curious endo- and exo- parasites from consulted materials is

interesting, too.

Prof. MUKOYAMA, Harutaka　向山明孝,　PhD　　

My research field is animal immunogenetics. We interest about relation with

Bovine MHC (BoLA class II DRB3) and mastitis resistance in dairy caw. We

investigated the crisis frequency of clinical mastitis and identification of

pathogens in Japanese Holstein cattle. And then the allele typing of BoLA DRB3

exon II in the mastitis caw was performed by nucleotide sequencing. At present

the potential relationships between amino acid motif in the peptide antigen

binding groove of various alleles of BoLA DRB3 and occurrence of clinical

mastitis caused by three pathogens are investigating. .

Prof. MURAMATSU, Umetaro　村松梅太郎,　DVM, PhD　

My interests are the problem of animal rights and the education program of

animal health technician. I am not an extreme critic supporting the right of

an animal. But I am very much interested in the theological difference between

Karl Barth and Albert Schweitzer on human-animal relationship.

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Research Associate NADE, Toshihiro, 撫　年浩,　PhD　

Since April 2006, I start working at NVLU, laboratory of animal nutrition.

My principal experiment field is efficient fattening method for the beef product.

My research focuses on the growth performance of beef cattle with an ultrasonic

measurement and the effect of the several fattening methods on the growth

performance of beef cattle.

Associate Prof. NAGAMATSU, Miki　永松美希,　PhD　

(1) Organic Agriculture

(2) AgriFood Supply Chain Development in Japan and EU

(3) Food Safety and Security System in AgriFood Chains

(4) Consumers’ Concern for Food Safety

(5) Farm Animal Welfare

Associate Prof. NAKAGAKI, Kazuhide　中垣和英,　DVM, MS, PhD　

The primary goal of my research is to understand the interaction between

host and parasite. Especially, I have been studying both sides of the host-

parasite interface. Viewing it from the side of the host, the wildlife as a view

of the host regularly comes into contact with many parasites without suffering

any severe responses. This is a very interesting target for a research work.

My interest is still tissue nematodes that dwell in immune competent organs.

It is fascinating to search the answer as to why such large pathogens cannot

be eliminated, even though a single allogeneic cell can be removed. According

to Darwinists, this may be the result of natural selection. This does not

fully answer the question. The deeper I understand the interaction, the more I

understand that it is impossible to simplify the answer. We have to probe what’s

going on in the interface of every case.

However, my current interest is the mode of the infection with Coronaviruses.

Now, I am studying a receptor-dependent or -independent infection and signal

transduction.

Research Associate NEZU, Yoshinori　根津欣典,　DVM, PhD　

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Associate Prof. NISHITANI, Jiro　西谷次郎 Bsc, Msc

My research field is systems management of the animal industry. My present

subjects are 1) the state of the small scale raising management, 2) the pricing

mechanism of pet, 3) the consumption trend of value added eggs.

Research Associate OCHIAI, Yoshitsugu　落合由嗣,　

I work in Division of Veterinary Public Health. Currently, I join a

couple of projects including epidemiology of viral zoonosis using serology

or molecular biology and virulence evaluation of bacteria isolated from food

environment. In the first project, we study on epidemiology of herpes B virus

infection in human and primates and are going to investigate prevalence of

some human and primate herpesviruses including herpes simplex virus (HSV)-1,

HSV-2 and herpes B virus in primates. We have developed fluorescent ELISA

using recombinant antigen, which can discriminate antibody to HSV-1, HSV-2

and Herpes B virus and then investigate serum samples from chimpanzee and

other primates. In the second project, we are going to investigate the

ability of Listeria monocytogenes strains, which we have isolated from

meats purchased from some markets, to invade into some cell lines including

epithelial and non-epithelial cells to evaluate the virulence of the pathogen

in the food environment. This study will help us to invasion mechanism of L.

monocytogenes into the host cells.

Associate Prof. ODAKE, Sachiko　小竹佐知子　PhD

Current research interests are flavor release from food (meat & dairy products)

during mastication, which is called “retronasal aroma”, and the chemometrix

method for the evaluation of food palatability and acceptability.

Prof. OGAWA, Takashi　小河　孝,　DVM, PhD　

One of my research interests involves spatial analyses of animal diseases

(Bovine Ephemeral Fever & Avian Influenza) in veterinary epidemiology. Another

one includes methodology of animal disease loss in veterinary economics.

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Research Associate OHASHI, Yuji　大橋雄二,　PhD　

My research interests include the ecology of intestinal microflora and host-

microbial interaction in gastrointestinal tract. I analyze the intestinal

microflora with not only the culture-based technique but also molecular

biological technique. With these techniques, I have investigated the colonic

fermentation system of intestinal bacteria and the influence of microbial

composition on the development of mucosal immune system and the physiological

function in the digestive tract.

Assistant Prof. OHKUSU-Tsukada, Kozo　塚田（大楠）晃三,　DVM, PhD　

Now my teaching field is veterinary pathology containing immunology. My research fields

are tumor immunology and inflammatory autoimmune diseases. Especially I am interested in the

regulation of the immunosuppressor cells such as IL-10-producing Foxp3+ CD4+ regulatory T

cells (Treg) and CD11b+ Gr-1+ myeloid suppressor cells (MSC). It is known that these cells

are increased in cancer and decreased in autoimmune diseases. I am trying to establish

the immunotherapy for cancer or autoimmune diseases by controlling the number of the

immunosuppressor cells. Before I moved here, I found a mechanism that a MAP kinase family in

cellular signaling pathways for the proliferation changed activation of p38 and inactivation

of ERK in IL-10-producing regulatory T cells. (Mol.Cell.Biol. 24; 6957-6966. 2004.) Now I

am trying to search the molecules relating with the proliferation of MSC to inhibit the

expansion of MSC in cancer. By controlling of the immunosuppressor cells in the future, I

try to execute the special immunotherapy using the tumor-antigen specific T cells in dogs and

cats.

Associate Prof. OHTA, Yoshiyuki　太田能之,　PhD　

Animal nutrition and physiology

Research Associate OKADA, Konosuke　岡田幸之助,　PhD　

The pig would be an excellent model for certain human biomedical approaches,

i.e. stem cell technologies, xenotransplantation and so on. Of these, embryonic

stem cell technologies will be an important step to achieve the above purpose

and such research requires a great number of high-quality embryos. Thus, my

goal is the establishment of reliable protocols for in vitro production of pig

embryos with in vitro systems. For this reason, I’m working in the fields of in

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vitro fertilization, intracytoplasmic sperm injection and embryo development in

the pig. I’m also approaching to other species, such as mouse and field vole,

using same techniques to investigate the differences between species.

Associate Prof. OMI, Toshinori　近江俊徳,　PhD　

My principal research interest is in human molecular genetics, especially,

genetic association study to common disease (Eur J Hum Genet. 2006),

molecular analysis in transfusion medicine (Transfusion 2004), and a personal

identification by DNA typing in forensic science. I also investigate a breeding

and genetics of miniature pigs because my grand father and co-worker developed

a “Ohmini”(http://www.ohminipig.com). This breed was raised on world watch

list for domestic animal diversity in Food and Agriculture Organization of the

United Nations. As a new research focus, I hope to develop of informative DNA

polymorphism for animal health or animal identification by the application of

molecular genetics to veterinary medicine.

Prof. ORIMA, Hiromitsu　織間博光,　DVM, PhD　

My interests include the fields of veterinary radiology and neurology. In the

field of radiology, I am interested in all modalities of imaging, especially in

magnetic resonance imaging (MRI) and X-ray computed tomography (CT). Ongoing

studies include the detection of epileptic foci with MRI and the evaluation

of epileptic brain damages by using diffusion-weighted MRI. In the field of

neurology, my research interests include studies on: 1) idiopathic epilepsy in

small animals; 2) the clinical application of electrophysiological techniques in

dogs and cats; and 3) neuromuscular diseases in small animals.

Associate Prof. OZAWA, Takeyuki　小澤壯行,　BAgri, MAgri, PhD　

Takeyuki conferred PhD degree in Dairy Farm Management System from Tokyo

University of Agriculture and Technology in 2000. His PhD thesis topic was to

seek fluctuation of dairy farm management in Japan. In 2000 he was appointed

Research Fellow to Massey University (New Zealand) to research pasture based

livestock farming systems. Since that time, Dr Ozawa has been working with his

colleague at Massey publishing refereed conference papers and refereed journal

papers together.His current research area includes adopting pasture based

ruminant farming systems management and livestock products marketing in Japan.

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Assistant Prof. SAITO, Kenichi　斉藤賢一,　PhD　

My broad research is the biological effect of electro magnetic field and EEG of

epilepsy.

I have conducted research on the biological effects of radio frequency (RF)

irradiation of the animals.

I found lethal, teratogenic, and delayed hatching effects of RF on developing

chick embryos. The average number of somites of the early chick embryo was

significantly smaller in the exposed group than in control.

I have developed an EEG recording method for conscious and freely moving mice,

and recorded on spike discharges by my method in the EEGs of sleeping El mice.

I succeeded in detecting foci of the spikes by applying the electric field

model, in which the surface potential was expressed as a function of distance

between the focus and each electrode based on Gauss' theorem. This paradigm will

be helpful in detection of the epileptic focus in obtaining an insight into the

mechanisms of spike genesis.

Prof. SAITO, Toru　齋藤　徹, DVM, MSc, PhD　

My research interests include the fields of comparative and experimental

medicine and veterinary ethology. My current research focuses on the effect of

pheromone and ultra vocalization emitted by rodent pups on sexual and maternal

behavior in rodents.

Prof. SAKO, Toshinori 左向敏紀, DVM, PhD

My research focuses is animal metabic and endocrinological disease. My

current is onset factors and insulin resistance in animal diabetes . My

interests are insulin therapy and supplement medical treatment for a diabetes

animal.

Assistant Prof. SASAKI, Noriyasu　佐々木典康, DVM, PhD　

My research and teaching interests are focused on veterinary biochemistry,

molecular biology and genetic engineering. I am particularly interested in

adipocyte metabolism and regulation of gene expression in obesity and diabetes.

I am also interested in regulation of intramuscluar adipocytes differentiation

in beef cattle. My current target molecules are adipocytekines including leptin

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and resistin.

Prof. SASAKI, Teruo　佐々木輝雄,　MEc

My research interests lie in the following five topics:

(1) The process of food distribution and trade.

(2) The promotional strategies for “local production for local consumption”

　 and the effects.

(3) The promotional strategies for “sustainable agriculture” and the 　

　 outcomes.

(4) Establishment of policies to increase food safety.

(5) The role of dietary habits in human well being.

Prof. SAWADA, Takuo　澤田拓士,　DVM, MS, PhD　

My broad research interests include etiological, genetical and immunological

characterization of pathogenic bacteria isolated from animals and humans, and

application of those characteristics for epidemiological analysis, diagnosis,

prevention and treatment of infectious diseases. I have been studying mainly

with Erysipelothrix and Pasteurella and the diseases caused by these bacteria

for many years. My area of undergraduate teaching include bacteriology,

bacterial infectious diseases in animals and bacterial zoonoses.

Prof. SHIMIZU, Kazumasa　清水一政,　DVM, PhD　

My research focuses mostly on the comparative pharmacology.

I am particularly interested in mechanisms of action of transmitters and other

substances on smooth muscle.

Assistant Prof. SHISHIDO, Makoto　宍戸　真,　MA　

One of my teaching and research interests is to study the uses of multi-

media equipment, so-called computer assisted language learning (CALL), so

that students can experience various situations where English is actually

used. As a theoretical background of my English teaching and the research

in the field of second language acquisition (SLA), I have been interested in

“Input Hypothesis” which Stephan Krashen has proposed. It claims that humans

acquire language in only one way － by understanding messages, or by receiving

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“comprehensible input.” In order to evaluate the teaching methods and materials

of my own creation, I have also been interested in studying “classroom oriented

research.” It concerns with the relationship between research findings in

language acquisition and what takes place in the language classroom.

Research Associate SOETA, Satoshi　添田　聡,　DVM，MVM，PhD　

My research works include the field of veterinary anatomy, experimental

pathology and comparative pathology. I have two major research themes; studies

on the mechanisms underlying endochondral ossification in various mammalian

species, and studies on the differentiation of the vomeronasal and main

olfactory system in the urodele amphibians.

I am particularly interested in the intralacunar ossification found in the

epiphyseal growth plate cartilage of mammals after maturation, and the function

of the olfactory systems containing two types of olfactory receptor neurons in

the Japanese newt.

Prof. SUGAWARA, Moriyuki　菅原盛幸,　PhD　

My current research is divided into 2 main areas:

1. Nuturitional biochemistry of herbivorous・・・We used the voles (Microtus

arvalis) as experimental animaleto introduced from Hungary. Thereafter, they

were successfully bred and increased in number in a room.

2. Early diagnosis of bovine mastitis・・・In attempting to prevent mastitis,

early diagnosis of bacterial infectionis very important. Active oxygen species

in milk can be quantified by measuring the chemiluminescence(CL) of luminal.

This suggest that the amount of active oxygen produced by polymorphonuclear

leukocytes in milk could be used as an indicator of mastitis.

Associate Prof.SUZUKI, Hiroetsu　鈴木浩悦,　DVM, PhD　

The aim of my research is to reveal physiological processes by comparing

the defective phenotypes with normal ones and to establish hereditary models

for studying human and animal diseases. In our laboratory (veterinary

physiology), we have established spontaneously mutated rat strains. They are HGN

(hypogonadism), OCD (osteochondrodysplasia), LDE (lethal dwarfism with epilepsy),

UUA (unilateral urogenital anomalies), HN (hydronephrosis), and PET (petite,

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thymic hypoplaisa). I have performed the pathophysiological examinations

(from whole body to cellular level) to characterize their phenotypes and

the positional candidate approach to identify the responsible genes for the

mutations. One of the success examples in my project is the identification of

the microtubule-associated protein, Spag5, as the responsible gene for severe

type of male hypogonadism. I also study the environmental effects (endocrine

disruptors and electromagnetic wave) on animal reproduction and development in

collaborations with internal and external researchers.

Prof. SUZUKI, Katsushi　鈴木勝士,　DVM, PhD　

Our driving hypothesis is to find out new important biological processes by

referencing with exceptionally low frequency statistical events seen in the

mutants. We have established 9 rat mutant-and-strains, mainly with an autosomal

recessive inheritance. Now we identified 4 such loci at chromosome levels, and

one responsible gene at the molecular level. Hereditary diseases in domestic

animals have been studied: I have chaired the association of the Veterinary

Clinical Genetics for 12 years. Another theme is to reveal developmental

interactions between genes and environment.　Chemical and physical teratogenesis

has been investigated in the rodent model. Endocrine disruptors have also

been studied. I have chaired the pesticide expert committee, the food safety

commission, Japan.

An outstanding progress has been made in detecting the origin of spikes in

the sleeping EEG in the EL mouse, which was based on the electro-magnetic field

theory but not on the current dipole theory.

Prof. TAGAWA, Masahiro　多川政弘,　DVM, PhD　

We have five faculty members in my division including me. Each faculty

cooperate with PhD course students for each research subject.

My research and teaching interests are concerning small animal disease

including dog and cat, especially anesthesia and analgesia, also including

shock, orthopedic surgery, and the regenerated medicine using in-vivo and

in-vitro studies. In my division, each faculty member are working in the

Veterinary Medical Teaching Hospital to have the clinic and the surgery, and

have education for our students. The practical results of each experiment, we

apply to our patients for the treatment and the diagnostic tool of various

surgical diseases.

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Prof. TAKAHASHI, Kimimasa　高橋公正,　DVM, PhD　

My specialty is veterinary pathology. I had devoted myself to studies of

toxicological pathology for 13 years before I moved to this university. My

current research interest is placed on the mechanism of tumorigenesis of feline

mammary tumor and of unique skin fibroma in Djungarian hamster. Almost all feline

mammary tumors unlike canine ones are considered to be potentially malignant. I

am interested in exploring the factors that are related to potential malignancy

of feline mammary tumor. Our laboratory revealed that male Djungarian hamster

has a strong predisposition to this atypical skin fibroma as compared to female,

and that the tumor cells express androgen receptors. I would like to demonstrate

experimentally that this tumor develops in an androgen-dependent manner.

Associate Prof. TAKEMURA, Naoyuki 　竹村直行, BVSc, MS, DVM, PhD　

My current research interests include (1) drug therapy and its effect on

survival in asymptomatic dogs and cats with chronic heart failure, (2) diagnosis

of early stage chronic renal disease in small animal, (3) effect of pain during

perioperative period on cardiac and renal function in small animal, and (4)

diagnosis, medical therapy and pathophysiology of diabetes insipidus in small

animal.

Prof. TANAKA, Minoru　田中　実,　PhD　

My research interests are physiological functions of prolactin and growth

hormone. These pituitary hormones have similar structures but different

physiological functions. I am currently focusing on molecular mechanisms of

their effects on neural and immune systems.

Research Associate TANAKA, Yoshikazu　田中良和,　MSc, DVM, PhD　

The long-term goal of my research includes the elucidation of the molecular

interactions between viral pathogens and the host response that are necessary

for the establishment of infectious diseases. I have two projects in the

field of veterinary hygiene. (1) Identification of the host factors that are

required in viral genome replication and propagation. (2) Screening of new

inhibitors for microbial diseases. I mainly focus on feline infectious diseases

(feline immunodeficiency virus and feline infectious peritonitis virus). I have

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established real time PCR conditions to measure viral molecules and inhibitory

methods of the viral protein expression with Si-RNA. We will develop recombinant

viral vectors carrying Si-RNA expression units.

Associate Prof. TAZAKI, Hiroyuki　田﨑弘之,　PhD　

My research interests include: chemical biology, natural product chemistry,

bioorganic chemistry. My research focuses mostly on the biosynthesis of

secondary metabolite of microorganisms, plant and animals. In our laboratory,

isolation and structure determination techniques for bioactive molecules by

using spectroscopic and chemical methods, stable-isotope labeling technique

for precursors of secondary metabolite, and function analysis of enzyme for

biosynthesis are available. In addition, metabolomic studies are also in

progress.

Assistant Prof. TOKITA, Norio　時田昇臣,　BSc, MSc, PhD　

My research interests include the fields of forage evaluation and animal

nutrition. In the field of forage evaluation, my research focuses on nutritive

values of tropical grasses and legumes. In the field of animal nutrition, I am

interested in fiber and protein digestion in herbivores and have focused on

potential digestibility of sheep, deer and ostriches.

Prof. TOMOGANE, Hiroshi　友金　弘,　PhD　

The area of investigation in my laboratory centers around prolactin genes

family, a pituitary and placental hormones that are important in development of

embryo and lactating mammary gland, and in corpora luteal function. My research

focuses on the molecular cloning of placental lactogen cDNA in field voles, on

the regulation of prolactin secretion in the various reproduction stages of

rats, and on the relation between polymorphisms of the 2nd exon of BoLA-DRB3

gene and occurrence of clinical mastitis in lactating cows. For these studies,

our members use a variety of molecular and cellular techniques, as well as whole

animal models, to identify the phenotype of prolactin gene family in various

phenomena during reproductive stages of experimental animals and to estimate

speciation of Microtus: field voles.

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Associate Prof. TSUCHIDA, Shuichi　土田修一,　DVM, PhD　

My research interests include genetic disorders and polymorphisms on companion

animals and oncology on small fish Medaka.

Assistant Prof. TSUSHIMA, Nobumichi　對馬宣道,　Bsc, PhD　

My broad research and teaching interests include physiology, hematology,

enzymology, environmental physiology, and behavior of various animals. Recent

research focuses on biosynthesis of protoporphyrin and heme, and their

degradation in various tissues of chicken mainly and mammals. One of my fields

of undergraduate teaching is environmental physiology including regulatory

mechanisms in body temperature of homeothermic animals. Other area of teaching

for undergraduate students is behavior of domestic animals and aves in special

reference to brain function.

Prof. TSUTSUI, Toshihiko　筒井敏彦,　DVD, PhD　

I specialize in companion animals, especially in the study of reproduction

of the dog and cat. I am working mainly on studies on the physiology of

reproduction, preventing estrus, transuterine migration of embryos, artificial

insemination (intravagina, intrauterus, intraoviduct), preservation of frozen

semen, in vitro fertilization, induction of ovulation, and embryo transfer

(intrauterus, intraoviduct). I am also concentrating on preservation frozen

epididymal sperms and the development of artificial insemination techniques using

this semen.

Prof. UEDA, Fukiko　植田富貴子,　DVM, BSc, PhD　

My research interests and teaching include: veterinary public health,

zoonoses, food safety, environmental Science, epidemiology and microbiology. My

research focuses mostly on the molecular epidemiology of Listeria monocytogenes

in Japan and the analysis of environmental contamination by heavy metals.

Associate Prof. WADA, Shinpei 　和田新平,　DVM, PhD　

My current research interests include histopathological diagnosis and clinical

medicine (clinical pathology, chemotherapy and surgery) of aquatic animals

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(mainly fishes). I have been teaching general fish medicine, special topics in

fish medicine and student practice in fish medicine from 1994.

Associate Prof. WASHIZU, Makoto　鷲巣　誠,　DVM, PhD　

Portosystemic shunt (PSS) study is our current interest of research. About 60

PSS cases are operated each year. MRI study of PSS cases demonstrated Manganese

accumulation in the basal ganglia of the brain. The accumulated Manganese

resolved after the surgical management. Helical CT imaging of shunt vessel is

a clear visualization of shunt vessel, which would be able to classify the

shunt patterns much clearly. Pathophysiology and management of post-operative

seizure is also our interest: hypoglycemia during shunt ligation and acupuncture

treatment in the early seizure activates.

Associate Prof. WASHIZU, Tsukimi　鷲巣月美,　DVM, PhD　

My major research interest is hepatobiliary diseases of the dog and cat,

especially the pathophysiology of congenital portosystemic shunts and juvenile

hepatic fibrosis. I am also working on developing the new diagnostic method for

canine lymphoma and mast cell tumor, and establishing the immunotherapy for

different kinds of tumors in the dog. Another area that I am studying is human

animal relations including service dogs for the physically handicapped and the

communication in clinical veterinary medicine including how to acquire the

appropriate communication skill for informed consent and second opinion, client

support for companion animal loss, and the proper communication technique in the

veterinary practice.

Research Associate YAGI, Shohei 　八木晶平,　MA　

My broad research interests include the field of development of food processing

technique: vegetables, soy bean seeds and garlic. My research focuses mostly

to research wider uses to vegetables, especially mechanism of pectin change in

blade vegetables, root crops and others of the low temperature steam heating

process.

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Assistant Prof. YAMAMOTO, Toshiaki 　山本俊昭,　PhD

My research is primarily focused on the fundamental and applied aspects of

freshwater ecology. In fundamental research, I have been working in behavioral

and evolutionary ecology such as the breeding system, the mechanism of

life history diversity and paternal and maternal effects using masu salmon

(Oncorhynchus masou). In applied research, I am interested in the effects of

the introduced species to native species and the ecosystem. I am currently

investigating the pattern and mechanism of an invasion of the introduced species

in rainbow trout (Oncorhynchus mykiss).

Research Associate YOGO, Takuya　余戸拓也,　DVM, PhD　

My research interests include veterinary ophthalmology. My research interests

lie in the following three topics:

(1) The genetic eye disease of guide dogs.

(2) The effects of phosphodiesterase inhibitors on contractility of eye

muscles.

(3) The effects of anti-inflammatory eye drops on uveitis eye.

Assistant Prof. YOKOSUKA, Makoto　横須賀誠,　DVM, PhD　

My research interests are focused on the neuralcircuit and physiological

function of the sensory nervous system. Especially, I am interested in the

morphological structures and recognition mechanism of the olfactory system. This

research must be critical for understanding the animal evolution and clinical

veterinary medicine.

Assistant Prof. YOSHIDA, Takaharu 　吉田孝治,　DVM, BAgr

The survey of Salmonella isolate from the healthy pigs in slaughterhouses. It

is the prevention of the salmonella disease of the pigs, and the attention is

urged to the occurrence of the salmonella infection of the human being.

Antibiotics sensitivity test to of Salmonella that isolated from the pigs.

I conjecture the relation between the clinical use frequency and resistant

bacteria appearance of antibiotics, and instruct the proper usage of the

antibiotics by it. And it is the important basic data of the treatment of the

salmonella infection of a pig and human.

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The gene analysis of Salmonella of antibiotics resistance.

The clarification of the acquisition mechanism of antibiotics resistance and

the background of genetics. Molecular typing of Salmonella that islated from the

pigs.

The molecular typing result is able to estimate the infection route to the pig

of salmonella.

Assistant Prof. YOSHIDA, Tatsuyuki 　吉田達行　MVSc　

I have researched about the early detection of abnormal quarter like mastitis

in cow, especially, focused on the relationships between mastitis indices,

such as electrical conductivity, pH, NAGase, and SCC, and milk yield and milk

quality. My current interests include the relationship between BoLA-DRB3 gene

and mastitis.

Associate Prof. YOSHIMURA，Itaru　吉村　格, PhD　

My research interest is on artificial insemination. I am conducting experiments

on cows, horses and sheep at the university research farm. While artificial

insemination is a practical way of assuring the food resources, we should not

leave out the ethical issues of depending on them. As the companion animal is

becoming part of the society, we need to pay more attention to how we treat

animal lives, as livestock or as a family member.

Assistant Prof. YUMOTO, Norio　湯本典夫,　DVM, DMs, PhD　

My research interests include the fields of comparative pathology and molecular

pathology. To date, My study was to determine the IgH or TCR nucleotide sequence

of lymphoma cell clones and to evaluate the properties of their antigen binding

sites, and , moreover, to understand the origin and the role of antigen in

the clonal selection of lymphoma cells. The results explain that the cells of

mucosa-associated lymphoid tissue lymphoma are autoantigen-related, and that

this lymphoma may be derived from selected autoreactive B-cell clone.

At the present, my research focuses mainly on investigating the relationship

of cell differentiation and tumorigenesis of lymphoproliferative disorders

by using molecular analysis of some genes associated with lymphoma in the

comparison of human with animal.

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日獣パンフBW.indd 42 2007/01/11 11:45:15

Edited by International Exchange Committee, NVLU, 2006

Members :

Prof. SAITO, Toru : Chairperson

Associate Prof. ODAKE, Sachiko : Vice Chairperson

Prof. HIROSE, Hisashi

Prof. AMASAKI, Hajime

Associate Prof. OMI, Toshinori

Associate Prof. OZAWA Takeyuki

Designed by Miss. AMASAKI Anna, 2006

Nippon Veterinary and Life Science University

1-7-1 Kyonan-cho, Musashino-shi, Tokyo 180-8602, JAPAN

Te l : +81-422-31-4151

Fax : +81-422-33-2094

E-mail : [email protected]

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日獣パンフBW.indd 44 2007/01/11 11:45:15

Documents

日獣パンフBW.indd 1 2007/01/11 11:45:07...Associate Professor AMAO Hiromi Assistant Professor KAWASUMI Koh 日獣パンフBW.indd 9 2007/01/11 11:45:09 NIPPON VETERINARY AND LIFE