Yonemura A et al. J Am Coll Cardiol 2005; 45:733-42.

Changes in vessel-wall thickness and vessel-wall area in the thoracic aorta Thoracic aorta Atorvastatin

20 mg (n=25 lesions)

Atorvastatin 5 mg (n=25 lesions)

p (20 mg vs 5 mg)

Maximal vessel-wall thickness

     

•Baseline (mm) 3.8 3.7 NS

•12 months (mm) 3.3 3.7 <0.05

•Change (%) -12.0 +1.0 <0.001

•p (compared with baseline)

<0.001 NS -

Vessel-wall area      

•Baseline (mm2) 135 135 NS

•12 months (mm2) 112 139 <0.05

•Change (%) -18.0 +4.0 <0.001

•p (compared with baseline)

<0.001 NS —

Yonemura A et al. J Am Coll Cardiol 2005; 45:733-42.

Changes in vessel-wall thickness and vessel-wall area in the abdominal aortaAbdominal aorta Atorvastatin

20 mg (n=35 lesions)

Atorvastatin 5 mg (n=40 lesions)

p (20 mg vs 5 mg)

Maximal vessel-wall thickness

     

•Baseline (mm) 3.3 3.2 NS

•12 months (mm) 3.3 3.3 NS

•Change (%) -1.0 +5.0 <0.02

•p (compared with baseline)

NS <0.01 —

Vessel-wall area      

•Baseline (mm2) 85 81 NS

•12 months (mm2) 87 89 NS

•Change (%) +3.0 +12.0 <0.05

•p (compared with baseline)

NS <0.001 —