Chapter 15: Signal Transduction

OUTLINE

15.1 From Extracellular Signal to Cellular Response15.2 Studying Cell-Surface Receptors15.3 Highly Conserved Components of Intracellular Signal-Transduction Pathways15.4 General Elements of G Protein-Coupled Receptor Systems15.5 G Protein-Coupled Receptors That Regulate Ion Channels15.6 G Protein-Coupled Receptors That Activate or Inhibit Adenylyl Cyclase15.7 G Protein-Coupled Receptors That Activate Phospholipase C

FIGURE 15-1General principles of signaling by cell-surface

FIGURE 15-2General schemes of intracellular signaling

15.1 From Extracellular Signal to Cellular Response

Signaling Molecules Can Act Locally or at a Distance

FIGURE 15-2(a)General schemes of intracellular signaling

FIGURE 15-2(b)General schemes of intracellular signaling

FIGURE 15-2(c)General schemes of intracellular signaling

FIGURE 15-2(d)General schemes of intracellular signaling

Extracellular Signal

Second Messengers

Reporter Constructs