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Flavonol Glycosides from Epimediumpubescens
F. Tu, Y. Dai, Z. Yao, X. Wang, X. Yao, and L. Qin
pp. 1317–1321
Simultaneous Determination of Ten Flavonoidsfrom Viscum coloratum Grown on DifferentHost Species and Different Sources by LC-MS
Y. Zhao, Z. Yu, R. Fan, X. Gao, M. Yu, H. Li, H. Wei, and K. Bi
pp. 1322–1328
Oleanene Glycosides of the Aerial Parts andSeeds of Bupleurum falcatum and the AerialParts of Bupleurum rotundifolium, and TheirEvaluation as Anti-hepatitis Agents
Y. Nakahara, M. Okawa, J. Kinjo, and T. Nohara
pp. 1329–1339
Garlicnin A from the Fraction RegulatingMacrophage Activation of Allium sativum
M. El-Aasr, Y. Fujiwara, M. Takeya, M. Ono, D. Nakano, M. Okawa, J. Kinjo, T. Ikeda, H. Miyashita, H. Yoshimitsu, and T. Nohara
pp. 1340–1343
ii
CHEMICAL & PHARMACEUTICAL BULLETIN
Vol. 59, No. 11 November 2011 © Copyright, 2011, by the Pharmaceutical Society of Japan.
Conten t s
Neolignans from Schisandra wilsoniana andTheir Anti-human Immunodeficiency Virus-1Activities
G.-Y. Yang, R.-R. Wang, H.-X. Mu, Y.-K. Li, W.-L. Xiao, L.-M. Yang, J.-X. Pu, Y.-T. Zheng, andH.-D. Sun
pp. 1344–1347
Three New Nortriterpene Glycosides and TwoNew Triterpene Glycosides from the Bulbs ofScilla scilloides
M. Ono, D. Toyohisa, T. Morishita, H. Horita, S. Yasuda, Y. Nishida, T. Tanaka, M. Okawa, J. Kinjo, H. Yoshimitsu, and T. Nohara
pp. 1348–1354
Photochemical Cleavage Reaction of 8-Quinolinyl Sulfonates That Are Halogenatedand Nitrated at the 7-Position
S. Ariyasu, K. Hanaya, M. Tsunoda, M. Kitamura,M. Hayase, R. Abe, and S. Aoki
pp. 1355–1362
Androgen Receptor Antagonists and Anti-prostate Cancer Activities of Some Synthesized Steroidal Candidates
S. A. Bahashwan, M. A. Al-Omar, E. Ezzeldin, M. M. Abdalla, A. A. Fayed, and A.-G. E. Amr
pp. 1363–1368
Discovery of a Novel Acyl-CoA: CholesterolAcyltransferase Inhibitor: The Synthesis,Biological Evaluation, and Reduced AdrenalToxicity of (4-Phenylcoumarin)acetanilideDerivatives with a Carboxylic Acid Moiety
M. Ogino, Y. Nakada, N. Negoro, S. Itokawa, S. Nishimura, T. Sanada, T. Satomi, S. Kita, K. Kubo, and S. Marui
pp. 1369–1375
Chemical & Pharmaceutical Bulletin Vol. 59, No. 11
iii
A nobel series of steroid derivatives were synthesized and theirandrogen receptor (AR) antagonist acyivities and in vivoantiandrogenic were evaluated.
Synthesis and Pharmacological Evaluation of1-Alkyl-N-[(1R)-1-(4-fluorophenyl)-2-methyl-propyl]piperidine-4-carboxamide Derivativesas Novel Antihypertensive Agents
S. Watanuki, K. Matsuura, Y. Tomura, M. Okada, T. Okazaki, M. Ohta, and S. Tsukamoto
pp. 1376–1385
Antitumor Effect of Liposomal HistoneDeacetylase Inhibitor-Lipid Conjugates in Vitro
Y. Hattori, Y. Nagaoka, M. Kubo, H. Yamasaku, Y. Ishii, H. Okita, H. Nakano, S. Uesato, and Y. Maitani
pp. 1386–1392
Notes
Two New Flavone C-Glycosides from Trollius ledebourii
L.-Z. Wu, H.-F. Wu, X.-D. Xu, and J.-S. Yang
pp. 1393–1395
Chemical Constituents from Sambucus adnataand Their Protein–Tyrosine Phosphatase 1BInhibitory Activities
T. Sasaki, W. Li, H. Morimura, S. Li, Q. Li, Y. Asada, and K. Koike
pp. 1396–1399
Adsorption of Cadmium Ions by Wheat BranTreated with Pectinase
F. Ogata, H. Tominaga, M. Kangawa, and N. Kawasaki
pp. 1400–1402
Two new flavone C-glyco-sides, trollisin A and B, were isolated from the flowers of Trollius ledebourii REICHB.
Chemical & Pharmaceutical Bulletin Vol. 59, No. 11
iv
New Solanocapsine-Type Tomato Glycosidefrom Ripe Fruit of Solanum lycopersicum
M. Ohno, M. Ono, and T. Nohara
pp. 1403–1405
Efficient Improved Extraction of TomatoSaponin Using Shock Waves
H. Manabe, A. Takemoto, H. Maehara, M. Ohno, Y. Murakami, S. Itoh, and T. Nohara
pp. 1406–1408
New Cannabinoid-Like Chromane andChromene Derivatives from Rhododendron anthopogonoides
N. Iwata and S. Kitanaka
pp. 1409–1412
Cytotoxicity of New 5-Phenyl-4,5-dihydro-1,3,4-thiadiazole Analogues
M. S. Alam, L. Liu, and D. U. Lee
pp. 1413–1416
Oleanolic Triterpene Saponins from the Rootsof Panax bipinnatifidus
N. H. Tung, T. H. Quang, N. T. T. Ngan, C. V. Minh,B. K. Anh, P. Q. Long, N. M. Cuong, and Y. H. Kim
pp. 1417–1420
Chemical & Pharmaceutical Bulletin Vol. 59, No. 11
v
Secolignans, Neolignans and Phenylpropanoidsfrom Daphne feddei and Their BiologicalActivities
Q.-F. Hu, H.-X. Mu, H.-T. Huang, H.-Y. Lv, S.-L. Li,P.-F. Tu, and G.-P. Li
pp. 1421–1424
Bioactive Phenolic Constituents from the Seedsof Pharbitis nil
K. H. Kim, S. K. Ha, S. U. Choi, S. Y. Kim, and K. R. Lee
pp. 1425–1429
Sesquiterpenes from the SecondaryMetabolites of Streptomyces sp. (YIM 56130)
Z. Yang, Y. Yang, X. Yang, Y. Zhang, L. Zhao, L. Xu, and Z. Ding
pp. 1430–1433
Chemical & Pharmaceutical Bulletin Vol. 59, No. 11
vi
About the cover: Photochemical bond-cleavage reactions are potentially useful in chemistry, bioorganic chemistry andmedicinal chemistry. We previously reported on a photochemical cleavage reaction of 8-quinolinyl sulfonate (8-QS)derivatives in aqueous solution at neutral pH, which we proposed to proceed via an excited triplet state. In this report, wereport on the synthesis of some new photocleavable 8-QS derivatives, in which halogen atoms or a nitro group was introducedat the 7-position, in an attempt to improve photoreactive properties and to produce a red-shift in the irradiation wavelength. Itwas found that 7-nitro-8-QS absorbs at �360 nm, and, as a result, the S–O bond of this compound can be cleaved byphotoirradiation with a fluorescent lamp in aqueous solution and on silicon surface. See the article by Ariyasu et al. on page1355 of this issue.