Organo-boron compoundsS 0040 DOI: 10.1002/chin.201111194

A Simple and General Platform for Generating Stereochemically Complex Polyene Frameworks by Iterative Cross-Coupling. — Boronates such as (IX) are employed to construct complex polyene frameworks, e.g. present in vacidin A. The approach involves the metal-selective cross-coupling of Sn/Ge bis-metalated olefins to generate polyenylgermanium intermediates followed by stereospecific iodode-germylations. All possible stereoisomers of polyenyl MIDA boronates are accessible by iterative coupling reactions. — (LEE, S. J.; ANDERSON, T. M.; BURKE*, M. D.; Angew. Chem., Int. Ed. 49 (2010) 47, 8860-8863, http://dx.doi.org/10.1002/anie.201004911 ; Dep. Chem., Univ. Ill., Urbana, IL 61801, USA; Eng.) — Klein

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