ChemInform Abstract: An Efficient Transformation from Benzyl or Allyl Halides to Aryl and Alkenyl Nitriles

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  • ChemInform 2010, 41, issue 45

    www.cheminform.wiley-vch.de

    NitrilesQ 0520 DOI: 10.1002/chin.201045068

    An Efficient Transformation from Benzyl or Allyl Halides to Aryl and Alkenyl Ni-triles. The tandem reaction includes a TBAB-catalyzed substitution using sodium azide and the following oxidative rearrangement with DDQ as an oxidant. Excellent functional group tolerance is shown. The reaction can be scaled up. (ZHOU, W.; XU, J.; ZHANG, L.; JIAO*, N.; Org. Lett. 12 (2010) 12, 2888-2891, DOI:10.1021/ol101094u ; State Key Lab. Nat. Biomimetic Drugs, Sch. Pharm. Sci., Peking Univ., Beijing 100083, Peop. Rep. China; Eng.) R. Steudel

    45- 068 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim

  • ChemInform 2010, 41, issue 45

    www.cheminform.wiley-vch.de 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim

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