2002 esterification, transesterification

esterification, transesterificationO 0315

10 - 068Facile Acylation of Sterically Hindered Alcohols Through KeteneIntermediates. — Carboxylic acids possessing strong electron-withdrawingsubstituents at the α-position acylate sterically hindered and chemicallysensitive alcohols in the presence of DCC in good yields. Deuteration andtrapping experiments corroborate the existence of ketene intermediates in thereaction. — (NAHMANY, MOSHE; MELMAN, ARTEM; Org. Lett. 3 (2001)23, 3733-3735; Dep. Org. Chem., Hebrew Univ., Jerusalem 91904, Israel; EN)

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