Oxazole derivativesR 0220 DOI: 10.1002/chin.201207105

Intermolecular and Selective Synthesis of 2,4,5-Trisubstituted Oxazoles by a Gold-Catalyzed Formal [3 + 2] Cycloaddition. — Trisubstituted 1,3-oxazoles are smoothly prepared by the intermolecular reaction of pyridine-N-aminides with ynam-ides tolerating a variety of functional groups. In contrast, acyclic ethylimidate (VII) is obtained under similar conditions from ynol ether (VI). — (DAVIES*, P. W.; CREMONESI, A.; DUMITRESCU, L.; Angew. Chem., Int. Ed. 50 (2011) 38, 8931-8935, http://dx.doi.org/10.1002/anie.201103563 ; Sch. Chem., Univ. Birmingham, Edgbaston, Birmingham B15 2TT, UK; Eng.) — S. Adam

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