2001 oxocarboxylic acids and esters

oxocarboxylic acids and esters (benzene compounds)Q 0460

46 - 086α-Ketocarboxylic Acid Based Inhibitors of Protein Tyrosine Phos-phatases. — Yersinia PTPase inhibitors can be simply prepared [cf. (II)] orare commercially available [cf. (III)]. The corresponding α-hydroxycarboxylicacids are found to be less active. — (CHEN, YEN TING; ONARAN, M.BURAK; DOSS, CHRISTOPHER J.; SETO, CHRISTOPHER T.; Bioorg.Med. Chem. Lett. 11 (2001) 14, 1935-1938; Dep. Chem., Brown Univ.,Providence, RI 02912, USA; EN)

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