2002 diastereoselective syntheses, enantioselective syntheses

diastereoselective syntheses, enantioselective syntheses (incl. cis/trans-isomerism)O 0031

37 - 030Regio- and Stereoselective Synthesis of Isoxazolines via CycloadditionReactions Using Pregnenolone as Chiral Auxiliary. — Asymmetric1,3-dipolar cycloaddition reaction of nitrile oxides (II) to olefins (I) is achievedusing pregnenolone as chiral auxiliary. This is the first example for the use ofsteroidal chiral auxiliaries in asymmetric synthesis. — (SHARMA, UTPAL;BORA, UTPAL; CHETIA, APURBA; BORUAH, ROMESH C.; SANDHU,JAGIR SINGH; Indian J. Chem., Sect. B: Org. Chem. Incl. Med. Chem. 41(2002) 5, 1012-1014; Org. Chem. Div., Reg. Res. Lab., Jorhat 785 006, India;EN)

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