ChemInform Abstract: Selective Debenzylation of Benzyl-Protected Groups with SiliaCat Pd(0) under Mild Conditions

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  • ChemInform 2011, 42, issue 45

    DeprotectionO 0345 DOI: 10.1002/chin.201145040

    Selective Debenzylation of Benzyl-Protected Groups with SiliaCat Pd(0) under Mild Conditions. Debenzylation of aryl benzyl ethers, benzyl esters, amino acids, and sugars proceeds smoothly under mild conditions leaving other sensitive groups in-tact. The method can also be applied to benzyl amine (IXa). The catalyst can be recy-cled and reused with a little loss of activity. (PANDARUS, V.; BELAND*, F.; CIRIMINNA, R.; PAGLIARO, M.; ChemCatChem 3 (2011) 7, 1146-1150, http://dx.doi.org/10.1002/cctc.201000420 ; SiliCycle Inc., Quebec City, Que. G1P 4S6, Can.; Eng.) S. Adam

    45- 040 2011 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim

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