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ChemInform Abstract: Studies on the Stereoselective Synthesis of the Marine Antitumor Agent Eleutherobin

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Page 1: ChemInform Abstract: Studies on the Stereoselective Synthesis of the Marine Antitumor Agent Eleutherobin

2000 terpenes

terpenesU 0200

40 - 172Studies on the Stereoselective Synthesis of the Marine AntitumorAgent Eleutherobin. — Total synthesis of sesquiterpene eleutherobin(I), starting from (S)-(+)-carvone, is of interest for comparison of its biologicalactivity with that of known cytotoxic taxol. — (CARTER, RICH; HOD-GETTS, KEVIN; MCKENNA, JEFF; MAGNUS, PHILIP; WREN, STEPHEN;Tetrahedron 56 (2000) 26, 4367-4382; Dep. Chem. Biochem., Univ. Tex.,Austin, TX 78712, USA; EN)

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