ChemInform 2009, 40, issue 28 © 2009 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim www.cheminform.wiley-vch.de Other bioactive products U 1300 Synthesis and Biological Evaluation of Decursin (IIb), Prantschimgin (Ib) and Their Derivatives. — Some of the synthesized coumarin derivatives show potent MDR reversal activity. In particular, pyridyl derivative (IIId) exhibits more potency than verapamil. — (XIA, Y.; MIN, K. H.; LEE*, K.; Bull. Korean Chem. Soc. 30 (2009) 1, 43-48; Mol. Cancer Res. Cent., Korea Res. Inst. Biosci. Biotechnol., Daejeon 305-806, S. Korea; Eng.) — H. Toeppel 28- 192

ChemInform Abstract: Synthesis and Biological Evaluation of Decursin (IIb), Prantschimgin (Ib) and Their Derivatives

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Page 1: ChemInform Abstract: Synthesis and Biological Evaluation of Decursin (IIb), Prantschimgin (Ib) and Their Derivatives

www.cheminform.wiley-vch.de

Other bioactive productsU 1300 Synthesis and Biological Evaluation of Decursin (IIb), Prantschimgin (Ib) and

Their Derivatives. — Some of the synthesized coumarin derivatives show potent MDR reversal activity. In particular, pyridyl derivative (IIId) exhibits more potency than verapamil. — (XIA, Y.; MIN, K. H.; LEE*, K.; Bull. Korean Chem. Soc. 30 (2009) 1, 43-48; Mol. Cancer Res. Cent., Korea Res. Inst. Biosci. Biotechnol., Daejeon 305-806, S. Korea; Eng.) — H. Toeppel

28- 192