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![Page 1: ChemInform Abstract: Synthesis and CNS Activity of Tricyclic Theophylline Derivatives. 8-Substituted Imidazo[2,1-f]theophyllines](https://reader031.pdfslide.net/reader031/viewer/2022020508/575003711a28ab1148992fc9/html5/thumbnails/1.jpg)
2000 alkaloids
alkaloidsU 0600
18 - 149Synthesis and CNS Activity of Tricyclic Theophylline Derivatives.8-Substituted Imidazo[2,1-f ]theophyllines. — Tricyclic theophyllinederivatives show sedative and analgesic activity. Derivative (VI) shows anti-serotonin and long-lasting hypothermic effects, whereas compound (VIII)is found to possess anticonvulsant activity. — (PAWLOWSKI, MACIEJ;DRABCZYNSKA, ANNA; KATLABI, JACEK; GORCZYCA, MARIA;MALEC, DANUTA; MODZELEWSKI, JERZY; Eur. J. Med. Chem. 34 (1999)12, 1085-1091; Dep. Pharm. Chem., Coll. Med., Jagiellonian Univ., PL-30-688Krakow, Pol.; EN)
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