Chemistry Year – Book 2002 · (analytical chemistry, biochemistry, environmental chemistry, inorganic chemistry, macromolecular chemistry, organic chemistry and physical chemistry)

Chemistry

Year – Book 2002 Faculty of Science

Masaryk University Brno

Masaryk Univer si t y Brno, Czech Republ ic, 2002

Section Chemistry

Chemistry Section is a unit of the Faculty of Science housed in three buildings at Kotlarska street and partly also outside at Kamenice street. Encompassing about one hundred academic staff, it offers a quality chemical education in bachelor’s program of chemistry, biochemistry and bachelor’s program for students of applied biochemistry. Besides graduate programme leading to a master degree in several areas of specialisation (analytical chemistry, biochemistry, environmental chemistry, inorganic chemistry, macromolecular chemistry, organic chemistry and physical chemistry) is available. In the same time bachelor’s program for teachers education as well as master degree program for them is offered. Graduate students may enter into the respective Ph.D. programmes.

Teaching activities are supported by a necessary research environment. A broad spectrum of modern chemical instruments enables thorough studies on chemical synthesis, molecular structure determination, trace element analysis and kinetics and mechanisms of chemical and biochemical processes, just to mention a few. There exists a significant cooperation with many universities and research institutes in Western Europe and U.S.A.

ORGANIZATIONAL STRUCTURE OF THE CHEMISTRY SECTION:

The Office Head Milan Potáček (Prof., RNDr., CSc.)

Deputy Head Zdeněk Glatz (Associate Prof., RNDr., CSc.)

Secretary Milena Urbánková

The Departments Analytical Chemistry

Biochemistry

Inorganic Chemistry

Organic Chemistry

Theoretical and Physical Chemistry

The Laboratories Laboratory of Atomic Spectrochemistry

and Research Centers Computer Laboratory

NMR Laboratory

Research Center for Environmental Chemistry and Ecotoxicology

Department of Analytical Chemistry with Division of Chemometrics

TEACHING AND RESEARCH ACTIVITIES

The department provides education in analytical chemistry including chemometrics: in bachelor studies for students of chemistry, biochemistry, biology and environmental science, in master studies for students of chemistry, biochemistry and environmental science, in postgraduate studies for specialists in analytical chemistry. External teaching activity also comprises basic, advanced and special lectures on analytical chemistry at the Faculty of Chemistry, Technical University, Brno.

The research involved the development of new analytical procedures and study of natural and newly synthesized substances (drugs, peptides, humic acids, etc.). Increasing accent was put on the development of new methods and instrumentation in the emerging field of bioanalytical chemistry. New analytical methods and approaches suitable for the determination of analytes in samples with complex matrix were developed. Chemometrical techniques such as Artificial Neural Networks combined with experimental design were routinely applied to optimize analyses. Attention was also paid to thermodynamic and kinetics study of complexation of transition metal ions (platinum group metal ions, copper(II), etc.) by various macrocyclic compounds, chemical model determination (equilibria, kinetics), chemical modelling (natural processes), chemistry of less common metals (f-elements, platinum metals, thallium, etc.), biocoordination chemistry (humic acids, macrocycles, drugs, etc.).

Capillary Electrophoresis (CE) was used for the study of humic substances of different origin (the study of oligomerisation, metal ion complexation, etc.). Also method for determination of some important analytes (sorbic acid, resveratrol, etc.) in wines was developed. Rapid screening methods for drug content of some drugs mentioned above in biological liquids were worked out and validated methods for determination of antiviral drugs like memantine and rimantadine were developed. CE instrumentation was also applied to determine chiral impurities. A CE instrument with laser-induced fluorescence detection was built in the department for both research and teaching purposes.

Matrix-assisted laser desorption/ionisation mass spectrometry (MALDI MS) played a key role in analysis and structural elucidation of biological compounds, such as peptides, peptide complexes and humic acids. In addition, it also served as a tool for analysis of small organic and inorganic compounds. Significant attention was paid to advanced sample preparation for an automated identification of proteins.

A chromatographic method for the analysis of adenine and cytosine as build-block molecules of DNA by reversed phase high performance chromatography (HPLC) was developed and compared with other techniques (CE, MALDI-TOF MS). In collaboration with industrial company, intensive study of reactive dyes by means of different experimental techniques was done.

Atomic absorption spectrometry (AAS) was used for the determination of metals, such as copper in biological samples. Dialysis and electrodeposition was applied for preconcentration of metals in flame AAS. Electrothermal atomic absorption spectrometry (ETAAS) was used for the determination of metals after electrodeposition on a graphite tube and graphite probe.

In Laboratory of atomic spectrochemistry, research activities are common with departmental. More details are given in a separate section.

DEPARTMENT STAFF

Head: Josef Havel (Prof., RNDr., D.Sc.)

Professor: Lumír Sommer (RNDr., D.Sc.), Professor Emeritus

Associate Professors: Vratislav Chromý (Ing., CSc.), part time Viktor Kanický (RNDr., CSc.) Josef Komárek (RNDr., CSc.) Vítězslav Otruba (RNDr., CSc.)

Assistant Professors: Marta Farková (RNDr., CSc.) Jan Havliš (Mgr., Dr.)

Přemysl Lubal (Mgr., Dr.) Karel Novotný (Mgr., Dr.) Jiří Pazourek (RNDr., Dr.) Jan Preisler (Mgr., Dr.) Jaroslav Šenkýř (Ing., CSc.)

Research Assistants: Dagmar Gajdošová (Ing.) Pavel Krásenský (Ing.) Klára Novotná (Ing.), part time

Technical Assistants: Helena Zavadilová (Ing.) Jitka Nováková

Secretary: Iva Šafaříková

Adjunct Lecturers: Miloš Bartušek (Prof., RNDr., CSc.) František Foret (Ing., CSc.), Institute of Analytical Chemistry, Academy of Sciences CR, Brno. Ludmila Křivánková (Assoc. Prof. RNDr., CSc.), Institute of Analytical Chemistry, Academy of Sciences CR, Brno. Miroslav Macka (RNDr., Ph.D.), University of Tasmania, Hobart, Australia. Karel Šlais (Assoc. Prof., RNDr., D.Sc.), Institute of Analytical Chemistry, Academy of Sciences CR, Brno.

Ph. D. Students: Full Time: Vlastimil Dohnal (Mgr.) Miloš Halúzka (Mgr.) Aleš Hrdlička (Mgr.) Radek Chalupa(Mgr.) Alice Kotulánová(Mgr.) Jiří Machát (Mgr.) Jiří Maleček (Mgr.) Sabina Malovaná (Mgr.) Martin Muzikář (Mgr.) Eva Niedobová (Mgr.) Lenka Pokorná (Mgr.) Pavla Polášková (Mgr.) Lubomír Prokeš (Ing.) Martin Semerád (Mgr.) Jitka Studýnková (Mgr.) Markéta Vašková (Mgr.) Partial Time: Klára Novotná (Ing.) Marie Pištěková (RNDr.) Michal Spěšný (Ing.) Šárka Winklerová (RNDr.)

FOREIGN Ph.D. STUDENTS AT THE DEPARTMENT:

Gaston Bocaz Beneventi (Universidad de Concepcion, Concepcion, Chile) Maria L. Pacheco Hernandéz (UAM, Mexico D. F., Mexico) Julio A. Soto Guerrero (UNAM, Mexico D. F., Mexico) THESES DEFENDED IN THE ACADEMIC YEAR 2001/2002

Diploma Theses

Tomáš Hottmar (J. Havel): Determination of Huperzin A using Capillary Electrophoresis

Pavlína Houserová (J. Komárek): Determination of Gold by Electrothermal Atomic Absorption Spectrometry

Soňa Humplíková (J. Havel): Separation and Determination of Monophosphatenucleotides, Markers of Hereditary Changes

Ilona Péterová (D. Gajdošová): Separation and Determination of Purine and Pyrimidine, Markers of Metabolic Disorders, using CE and MALDI TOF MS

Ivona Svobodová (P. Lubal): Complexation Study of Transition Metal Ions with Derivatized Macrocyclic Ligands of Cyclen/Cyclam Type

Jaroslav Šebela (K. Novotný): Optical Emission Spectrometry with Inductively Coupled Plasma and Laser Ablation in Analysis of Steels

Ondrej Šedo (J. Havel): Peptide Analysis Using MALDI-TOF Mass Spectrometry

Šenk Petr (V. Otruba): Optical Emission Spectrometry with Inductively-Coupled Plasma and Laser Ablation for Analysis of Glasses

Petr Táborský (P. Lubal): Protonation and Complexation Study of Rare Earth Elements with Bioligands and Macrocyclic Ligands Concerning Donor Atoms N, O, P

Vaculovič Tomáš (V. Kanický) The Influence of Additional Gases on Optical Emission Spectrometry with Inductively Coupled Plasma and Laser Ablation in Analysis of Steels

PhD Thesis

Martin Muzikář (J. Havel): Development of New Metods for the Determination of Inorganic Ions and Metals by Capillary Electrophoresis and Inductively Coupled Plasma Spectrometry

Vlastimil Dohnal (J. Havel): Method Development in Capillary Electrophoresis and Applications

Sabina Malovaná (J. Havel): HPLC of Natural Polyphenolic Compounds and CZE of Pyridinium Aldoximes

Jiří Maleček (J. Havel): Electrophoretic Study of Cu(II) with Selected Ligands

Maria de Lourdes Pacheco (J. Havel): Capillary Electrophoresis and MALDI-TOF Mass Spectrometry of Humic Acids

Julio Soto-Guerrero (J. Havel): Uranyl Complexation with Some Dicarboxylic Acids and Uranium Determination with MALDI-TOF Mass Spectrometry

Gaston Bocaz-Beneventi (J. Havel): Capillary Electrophoresis, MALDI-TOF Mass Spectrometry and Artificial Neural Networks in Forensic and Legal Medicine

LIST OF PUBLICATIONS

Scientific papers

BOCAZ BENEVENTI, G. G., TAGLIARO, F., BORTOLOTTI, F., HAVEL, J. Capillary zone electrophoresis and artificial neural networks for estimation of the post-mortem interval (PMI) using electrolytes measurements in human vitreous humour. INTERNATIONAL JOURNAL OF LEGAL MEDICINE, NEW YORK : SPRINGER-VERLAG, 116, 1, p. 5-11, 7 pp, 2002.

BOCAZ BENEVENTI, G. G., TAGLIARO, F., BORTOLOTTI, F., MANETTO, G., HAVEL, J. Capillary zone electrophoresis and artificial neural networks for estimation of the post-mortem interval (PMI) using electrolytes measurements in human vetreous humour. International journal of legal medicine, Germany : Springer, 116, 1, p. 5-10, 2002.

BOCAZ-BENEVENTI, G., LATORRE, R., FARKOVÁ, M., HAVEL, J. Artificial neural networks for quantification in unresolved capillary electrophoresis peaks. Analytica Chimica Acta, Amsterdam : Elsevier Science Publishers, 452, 1, p. 47-63, 2002.

DOBIÁŠOVÁ, Z., PAZOUREK, J., HAVEL, J. Simultaneous determination of trans-resveratrol and sorbic acid in wine by capillary zone electrophoresis. Electrophoresis, Weinheim : WILEY-VCH Verlag GmbH, 23, 2, p. 263-267, 2002.

FARKOVÁ, M., HAVEL, J. UMĚLÉ NEURONOVÉ SÍTĚ V ANALYTICKÉ CHEMII (ARTIFICIAL NEURAL NETWORKS IN ANALYTICAL CHEMISTRY). Chemické listy, Praha : Česká společnost chemická, 96, 6, p. 464-465, 2002.

HAVEL, J., LUBAL, P., FARKOVÁ, M. Evaluation of chemical equilibria with the use of artificial neural networks. POLYHEDRON, OXFORD : PERGAMON-ELSEVIER SCIENCE LTD, 21, 14-15, p. 1375-1384, 10 pp, 2002.

HAVEL, J., LUBAL, P., FARKOVÁ, M. Evaluation of Chemical Equilibrium Data with the Use of Artificial Neural Networks. Polyhedron, Velká Británie : Elsevier Science Ltd., 21, 14-15, p. 1375-1384, 2002.

HAVEL, J., SOTO-GUERRERO, J. A., LUBAL, P. Spectrophotometric study of uranyl-oxalate complexation in solution. POLYHEDRON, OXFORD : PERGAMON-ELSEVIER SCIENCE LTD, 21, 14-15, p. 1411-1420, 10 pp, 2002.

HAVEL, J., SOTO-GUERRERO, J. A., LUBAL, P. Spectrophtometric Study of Uranyl-oxalate Complexation in Solution. Polyhedron, Velká Británie : Elsevier Science Ltd., 21, 14-15, p. 1411-1420, 2002.

HAVLIŠ, J., TRBUŠEK, M. 5-methyl-cytosine as a marker for monitoring of DNA methylation. Journal of Chromatography B, Amsterdam : Elsevier, 781, 1-2, p. 373-391, 2002.

JUREČKA, P., VOJTÍŠEK, P., NOVOTNÝ, K., ROHOVEC, J., LUKEŠ, I. Synthesis, characterisation and extraction behaviour of calix[4]arene-based phosponic acids. Journal of the chemical society. Perkin transactions II, Physical organic chemistry, London : Chemical society, 2002, 7, p. 1370-1377.

KOTULANOVÁ, A., KOMÁREK, J. Determination of Copper in Biological Materials by Atomic Absorption Spectrometry.. Acta Chim. Slov., Ljubljana, Slovenia : Slovenian chemical society, 49, 3, p. 437-445, 2002.

LI, H., ZHANG, Y., POLÁŠKOVÁ, P., HAVEL, J. Enhancement of precision in the analysis of medicines by capillary electrophoresis using artificial neural networks. ACTA CHIMICA SINICA, BEIJING : SCIENCE CHINA PRESS, 60, 7, p. 1264-1268, 5 pp, 2002.

MACHÁT, J., KANICKÝ, V., OTRUBA, V. Determination of Selenium in Blood Serum by Inductively Coupled Plasma Atomic Emission Spectrometry with Pneumatic Nebulization. Analytical and Bioanalytical Chemistry, Heidelberg : Springer, 372, 4, p. 576-581, 2002.

MACHÁT, J., OTRUBA, V., KANICKÝ, V. Spectral and non-spectral interferences in determination of selenium by inductively coupled plasma atomic emission spectrometry. Journal of analytical atomic spectrometry, Cambridge : Royal Society of Chemistry, 17, 9, p. 1096-1102, 2002.

MALOVANÁ, S., FRIAS-GARCIA, S., HAVEL, J. Artificial neural networks for modeling electrophoretic mobilities of inorganic cations and organic cationic oximes used as antidote contra nerve paralytic chemical weapons. ELECTROPHORESIS, WEINHEIM : WILEY-V C H VERLAG GMBH, 23, 12, p. 1815-1821, 7 pp, 2002.

MIKOLÁŠ, J., MUSIL, P., STUCHLÍKOVÁ, V., NOVOTNÝ, K., OTRUBA, V., KANICKÝ, V. Infrared laser ablation study of pressed soil pellets with inductively coupled plasma atomic emission spectrometry. Analytical and Bioanalytical Chemistry, Heidelberg : Springer, 374, 2, p. 244-250, 2002.

MOYA-HERNANDEZ, R., RUEDA-JACKSON, J. C., RAMIREZ, M. T., VAZQUEZ, G. A., HAVEL, J., ROJAS-HERNÁNDES, A. Statistical Study of Distribution Diagrams for Two-Component Systems: Relationship of Means and Variances of the Discrete Variable Distributions with Average Ligand Number and Intrinsic Buffer Capacity. Journal of Chemical Education, Madison, Wisconsin : American Chemical Society, 79, 3, p. 389-392, 2002.

MUZIKÁŘ, M., HAVEL, J., MACKA, M. Capillary electrophoretic study of interactions of metal ions with crown ethers, a sulfated beta-cyclodextrin, and zwitterionic buffers present as additives in the background electrolyte. ELECTROPHORESIS, WEINHEIM : WILEY-V C H VERLAG GMBH, 23, 12, p. 1796-1802, 7 pp, 2002.

PAZOUREK, J., PERRIN, C., MASSART, L. Calibration of Chiral Compounds with Self-Internal Standard. Application to Determination of S(-)-propranolol Hydrochloride by Capillary Zone Electrophoresis. Chromatographia, Friedrich Vieweg a synové, 56, 9/10, p. 597-603, 2002.

POLÁŠKOVÁ, P., BOCAZ BENEVENTI, G. G., LI, H., HAVEL, J. Evaluation of calibration data in capillary electrophoresis using artificial neural networks to increase precision of analysis. JOURNAL OF CHROMATOGRAPHY A, AMSTERDAM : ELSEVIER SCIENCE BV, 979, 1-2, p. 59-67, 8Increase pp, 2002.

REICHOVÁ, N., PAZOUREK, J., POLÁŠKOVÁ, P., HAVEL, J. Electrophoretic behavior of adamantane derivatives possessing antiviral activity and their determination by capillary zone electrophoresis with indirect detection. Electrophoresis, Weinheim : WILEY-VCH Verlag GmbH, 23, 2, p. 259-262, 2002.

SANCHEZ, M.J., HIDALGO, M., HAVEL, J., SALVADO, V. The speciation of rhodium(III) in hydrochloric acid media by capillary zone electrophoresis (The speciation of rhodium(III) in hydrochloric acid media by capillary zone electrophoresis). Talanta, Elsevier Science, 56, 2, p. 1061-1071, 2002.

Abstracts of conference papers and posters

FARKOVÁ, M., HAVEL, J. Umělé neuronové sítě (ANN) v chemii. Kvantitativní analýza z nerozlišených píků v kapilární elektroforéze s použitím vícerozměrné kalibrace kombinací plánování pokusů a ANN (Artificial neural networks (ANN) in chemistry. Quantitative analysis from unresolved peaks in capillary electrophoresis using multivariate calibration with the combination of experimental design and ANN). In Program přednášek 17. Chemometrického dne. p. 8-8, 2002.

HAVEL, J., FARKOVÁ, M. CAPILLARY ELECTROPHORESIS CHIRAL SEPARATION MODELLING WITH THE USE OF ARTIFICIAL NEURAL NETWORKS. In CHIRANAL 2002. p. 65-65.

LUBAL, P., HAVEL, J., FARKOVÁ, M. ANN Prediction of Equilibrium Constants in Aqueous Solutions. In Book of Abstracts of International Chemometric Conference CHEMOMETRICS VI. p. P15, 1 pp, 2002.

LUBAL, P., HAVEL, J., FARKOVÁ, M. ANN Prediction of Migration Behaviour of Metal Complexes in Capillary Zone Electrophoresis. In Book of Abstracts of International Chemometric Conference Chemometrics VI. p. P14, 1 pp, 2002.

MACHÁT, J., OTRUBA, V., KANICKÝ, V. Matrix interferences in determination of selenium by inductively coupled plasma - atomic emission spectrometry. In 2002 Winter Conference on Plasma Spectrochemistry. p. 224-225.

MUZIKÁŘ, M., FARKOVÁ, M., HAVEL, J. SOFT MODELLING OF ELECTROPHORETIC MOBILITIES AND PREDICTION OF ANIONS RESOLUTION USING ARTIFICIAL NEURAL NETWORKS. In CHEMOMETRICS VI. p. P17, 1 pp, 2002.

NOVOTNÝ, K., ŠEBELA, J., OTRUBA, V., KANICKÝ, V. Využití rychlé sekvenční ICP spektrometrie pro analýzu ocelí ve spojení s laserovou ablací (Using of a rapid sequential ICP spectrometry with laser ablation for the analysis of steels). In Hutní analytika 2002. p. 15-19.

PAZOUREK, J., MASSART, L. Robustness Test in Development of Capillary Electrophoresis Analytical Method of Chiral Compounds. In Book of ABstracts International Chemometric Conference Chemometrics VI. p. P1, 1 pp, 2002.

TOPINKOVÁ, J., TRNKOVÁ, L., HAVEL, J. Use of artificial neural networks for the evaluation UV-Vis spectra of adenine and cytosine in mixtures. In Chemické listy. p. 482-482, 2002.

TRNKOVÁ, L., PEŇA-MENDEZ, E. M., TOPINKOVÁ, J., HAVEL, J. Partial least squares and artificial neural networks for multicomponent analysis from derivative UV-Vis spectra. In International Chemometric Conference - CHEMOMETRICS VI. p. P21, 1 pp, 2002.

VACULOVIČ, T., NOVOTNÝ, K., KANICKÝ, V., OTRUBA, V. The influence of atmosphere composition in the ablation chamber on the analysis of steels by inductively coupled plasma atomic emission spectrometry LA-ICP-AES. In Book of Abstracts XVI-th Slovak Spectroscopic conference. p. 49-49, 2002.

Other professional publications DOHNAL, V., LI, H., FARKOVÁ, M., HAVEL, J. Quantitative Analysis of Chiral Compounds from Unresolved Peaks in Capillary Electrophoresis using Multivariate Calibration with Experimental Design and Artificial Neural Networks. Chirality, New York : John Wiley & Sons, Inc., 14, 6, p. 509-518, 2002.

FORET, F., PREISLER, J. Liquid phase interfacing and miniaturization in matrix-assisted laser desorption/ionization mass spectrometry. Proteomics, Weinheim : Wiley-VCH, 2, 4, p. 360-372, 2002.

HAVLIŠ, J., SHEVCHENKO, A., SHEVCHENKO, A. Protein Identification by MALDI TOF MS: Practical Assessment of the Fast In-gel Digestion Protocol, 2002.

KANICKÝ, V., LUBAL, P., HAVEL, J. SPEKTROFOTOMETRICKÉ STUDIUM SOLVATAČNÍCH ROVNOVÁH URANU(VI) S N, N - DIMETHYLFORMAMIDEM. CHEMICKÉ LISTY, Praha : Česká

společnost chemická, 96, 6, p. 474-474, 2002.

KOMÁREK, J., HOUSEROVÁ, P. Determination of Gold by Electrothermal AAS after Deposition on a Graphite Tube. In 5th European Furnace Symposium and 10th International Solid Sampling Colloquium with Atomic Spectroscopy. Book of abstracts. p. 101-101, 2002.

KOTEK, J., LUBAL, P., HERMANN, P., CÍSAŘOVÁ, I., LUKEŠ, I., GODULA, T., MALEČEK, J., SVOBODOVÁ, I., TÁBORSKÝ, P., HAVEL, J. NEOBVYKLE VÝJIMEČNÁ TERMODYNAMICKÁ STABILITA A KINETICKÁ STÁLOST MĚĎNATÝCH KOMPLEXŮ 1,8-BIS(METHYLFOSFONOVÝCH DERIVÁTŮ CYKLAMU. CHEMICKÉ LISTY, Praha : Česká společnost chemická, 96, 6, p. 353-353, 2002.

LUBAL, P., KOTEK, J., HERMANN, P., LUKEŠ, I. Complexes of 1,4,8,11-tetraazacyclotetradecane-1,8-bis(methylphosphonic acid) and similar ligands. In Book of Abstracts of International Conference on Coordination Chemistry ICCC'35, 2002.

LUBAL, P. NEPŘÍMÉ KINETICKÉ STANOVENÍ MANGANISTANU A DICHROMANU VE SMĚSI. CHEMICKÉ LISTY, Praha : Česká společnost chemická, 96, 6, p. 457-457, 2002.

MACHÁT, J., OTRUBA, V., KANICKÝ, V. Spectral and non-spectral interferences in determination of selenium by inductively coupled plasma - atomic emission spectrometry. In XVIth Slovak spectroscopic conference. Book of abstracts. p. 39-39, 2002.

MÁLKOVÁ, M., RUDOVSKÝ, J., LUBAL, P., KUBÍČEK, V., HERMANN, P., LUKEŠ, I. A Novel Bifunctional Mono9phosphinate) Analog of DOTA, DO3A-P(O)(OH)-(CH2)2COOH. Potentiometric and kinetic studies. In Book of Abstracts of International Conference on Coordination Chemistry ICCC'35, 2002.

MARŠÁLEK, P., FARKOVÁ, M., HAVEL, J. Quantitative MALDI TOFMS Analysis of Amino Acids Applying Soft Modeling Methods. Chemical Papers, Bratislava : Slovak Academic Press, 56, 3, p. 188-193, 2002.

NIEDOBOVÁ, E., KANICKÝ, V., OTRUBA, V. Determination of iodine in biological samples by ICP-OES in VUV region. Praha (Czech Republic) : Česká společnost chemická, 96(S), Symposiap. 303-305, 2002.

NOVOTNÝ, K., KOMÁREK, J. Preconcentration of Divalent Metal Ions for Flame AAS by Donnan Dialysis with Nafion Capillary Membrane. In XVIth Slovak Spectroscopic Conference. Book of abstracts. p. 74-74, 2002.

PACHECO HERNÁNDEZ, M. D. L., HAVEL, J. Capillary zone electrophoresis of humic acids from the American continent. 10 pp, 2002.

PAZOUREK, J., MASSART, L. Electrophoresis Of Chiral Compounds. Calibration For Chiral Sample Consisting Of Two Enantiomers. 1 pp, 2002.

PREISLER, J., HU, P., KARGER, B. L., REJTAR, T., MOSKOVEETS, E. Capillary Array Electrophoresis-MALDI Mass Spectrometry Using a Vacuum Deposition Interface. Analytical Chemistry, Washington, D.C., USA : American Chemical Society, 74, 1, p. 17-25, 2002.

PREISLER, J. Příprava vzorku pro MALDI MS metodou nanášení ve vakuu (Sample Preparation for MALDI MS using Vacuum Deposition). In Chemické listy. p. 465-465, 2002.

PROKEŠ, L., KANICKÝ, V., OTRUBA, V. Elemental analysis of the skeletal remains of two Moravian population groups from the Great Migration Period. Chemické listy, 96, Symposia, p. S308, 4 pp, 2002.

REJTAR, T., PING, H., JUHASZ, P., CAMPBELL, J. M., VESTAL, M. L., PREISLER J., KARGER, B.L. Off-Line Coupling of High-Resolution Capillary Electrophoresis to MALDI-TOF and TOF/TOF MS. Journal of Proteome Research, Washington, USA : ACS, 1, 2, p. 171-179, 2002.

SHEVCHENKO, A., SCHAFT, D., ROGUEV, A., PIJNAPPEL, P., HAVLIŠ, J., STEWART, F., SHEVCHENKO, A. SEAMing Proteins from the TAP: Charting Protein Interaction Networks in Yeast by Tandem Affinity Purification and Mass Spectrometry, 2002.

SVOBODOVÁ, I., LUBAL, P., KOTEK, J., HERMANN, P., LUKEŠ, I., HAVEL, J. STUDIUM KOORDINAČNÍCH VLASTNOSTÍ KOMPLEXŮ 1,8-BIS(METHYLENFOSFONOVÝCH) DERIVÁTŮ CYKLAMU. CHEMICKÉ LISTY, Praha : Česká společnost chemická, 96, 6, p. 383-383, 2002.

TÁBORSKÝ, P., LUBAL, P., CÍGLER, P., HERMANN, P., KOTEK, J., LUKEŠ, I., HAVEL, J. Formation and Dissociation Study of Macrocylic Ligand DO3A with Transition Metal Ions. In Book of Abstracts of International Conference on Coordination Chemistry ICCC'35, 2002.

TÁBORSKÝ, P., LUBAL, P., CÍGLER, P., HERMANN, P., KOTEK, J., LUKEŠ, I., HAVEL, J. STUDIUM FORMAČNÍ A DISOCIAČNÍ KINETIKY MAKROCYKLICKÉHO LIGANDU DO3AP S VYBRANÝMI IONTY KOVŮ. CHEMICKÉ LISTY, Praha : Česká společnost chemická, 96, 6, p. 385-385, 2002.

VERNER, J., POTÁČEK, M., HAVEL, J. NOVEL APPROACH TOWARDS THE OPTIMIZATION OF ORGANIC SYNTHESES USING EXPERIMENTAL DESIGN. 2 pp, 2002.

VRÁBEL, P., PREISLER, J., HAVEL, J., KRÁSENSKÝ, P. Vývoj a charakterizace přístroje pro kapilární elektroforézu s laserem indukovanou fluorescenční detekcí (Development and Characterization of a Capillary Electrophoresis Instrument with Laser-Induced Fluorescence Detection). In Chemické listy. p. 459-460, 2002.

CONFERENCES (SYMPOSIA, SEMINARS) ORGANIZED BY THE DEPARTMENT STAFF MEMBERS: 13

54. Meeting of Chemical Societies, June 30 – July 4, 2002, Brno, Czech Republic, J. Preisler (treasurer), J. Havel.

International Chemometrics Conference CHEMOMETRICS VI, September 1 – 5, 2002, Brno, Czech Republic: Havel, J. (president), Farková, M. (chairman), Gajdošová, D., Krásenský, P., Nováková, J., Novotná, K., Lubal, P., Pazourek, J., Preisler, J., Šafaříková, I., Zavadilová, H.

GRANTS BESTOWED FOR PROJECTS

EU COST D18/0001/99

Havel, J., Lubal, P.: Luminescent Lanthanide Complexes in Analytical and Diagnostic Applications. Collaboration. Resposible holder: Department of Inorganic Chemistry, Faculty of Natural Sciences, Charles University, Lukeš, I.

GAČR 203/02/0493

Havel, J., Lubal, P.: Bifunctional chelates. Synthesis and complexing properties. Resposible holder: Department of Inorganic Chemistry, Faculty of Natural Sciences, Charles University, Lukeš I.

FRVŠ 793/2002

Preisler, J., Havel, J., Vrábel, P.: Capillary Electrophoresis with Laser-Induced Fluoresce (LIF) Detection for Advanced Laboratory Ptactice.

GAČR 203/02/P097

Novotný, K.: The study of interaction of laser radiation with solid materials by plasma spectrometry methods.

GAČR 203/02/1103

Farková, M., Havel, J.: Artificial Neural Networks and Experimental Design in Analytical Chemistry, Especially in Separation Methods.

RAWRA, Prague, Czech Rep.; OECD Nuclear Energy Agency, Paris, France

Havel, J., Lubal, P.: Thermodynamic database II.

INDUSTRIAL COOPERATION

Pliva-Lachema, Brno, Czech Republic.

INVITED LECTURES AND WORKING STAYS OF STAFF MEMBERS ABROAD

Havel, J., University Santiago del Compostela, Department of Inorganic Chemistry, Santiago del Compostela, Spain, 1 week.

Havel, J., Universidad Autonoma de Barcelona, Dept. Analytical Chemistry, Barcelona-Bellaterra, Spain, 1 week.

Havel, J., University of Girona, Department of Analytical Chemistry, Girona, Spain, 1 week.

Havel, J., Northwest University, Department of Chemistry, Xián, China, 1 week.

Havel, J., The use of Artificial Neural Networks in Analytical Chemistry, Charles University, Department of Analytical Chemistry, Faculty of Science, Prague, May 2002, invited lecture.

Havel, J., Artificial Neural Networks in Separation Science, University of Vienna, Department of Chemistry, 23.05.2002, invited lecture.

Havel, J., "Artificial Neural Networks in Separation Science" (for optimization and-or method Development), Universidad Autonoma de Barcelona, UAB, Barcelona, Department of Analytical Chemistry, 11.06.2002, invited lecture.

Havel, J., " Artificial Neural Networks in Separation Science", Universidad de Girona, Girona, 12.06.2002, invited lecture.

Havel, J., Artificial Neural Networks in Chemistry, Dept. of Chemistry, Northwest University, Xián, Peoples Republic of China, October 16, 2002, invited lecture.

Havel, J., Capillary Electrophoresis, Theory and Application, Nortwest University, Department of Chemistry, Xián, Peoples Republic of China, October 21, 2002, invited lecture.

Kanický, V., May 2002, University of Cordoba, Department of Physics, (prof. M. Carmen Quintero) 1 week.

Kanický, V., April 2002, Université Claude Bernard, (dr. Jean-Michel Mermet), 1 week.

Kanický, V., June 2002, XV th Slovak Spectroscopic Conference, Košice, Slovakia, (prof. Erika Krakovská).

Kanický, V., June 2002, Swiss Federal Institute of Technology, Zurich, (prof. Detlef Guenther), participation at the international workshop on laser ablation ICP mass spectrometry.

Kanický, V., June 2002, Utrecht, Netherlands, participation at the conference on laser ablation ICP mass spectrometry.

Kanický, V., July 2002, Université Claude Bernard, (dr. Jean-Michel Mermet), 2 weeks.

Kanický, V., October 2002, Swiss Federal Institute of Technology, Zurich, (prof. Detlef Guenther), 2 weeks.

Lubal, P., 2002, April Adam Mickiewicz University, Poznan, Poland, 1 week.

Lubal, P., 2002, May - June - Universidad de Barcelona, Spain, 1 month.

Lubal, P., Eidgenossische Technische Hochschule (Department of Inorganic Chemistry), Zürich, Switzerland, (Prof. G. Anderegg), research stay.

Otruba, V., May 2002, University of Cordoba, Department of Physics, (prof. M. Carmen Quintero) 1 week.

Otruba, V., April 2002, Université Claude Bernard, (dr. Jean-Michel Mermet) 1 week.

Otruba, V., July 2002, Université Claude Bernard, (dr. Jean-Michel Mermet) 2 weeks.

Preisler, J., November 2002, Barnett Institute/NEU, Boston, USA, 1 week.

OTHER INTERNATIONAL CONTACTS AND CO-OPERATIONS OF STAFF MEMBERS

Cooperation

Université Louis Pasteur, Ecole Européenne des Hautes Études des Industries Chimiques de Strasbourg, Department of Bioinorganic Chemistry, Strasbourg, France (Prof. A.-M. Albrecht-Gary; J. Havel).

Université Paris 7, France (Prof. J. P. Doucet; J. Havel).

Free University Brussels, Farmaceutical Institute, Belgium (Prof. D. L. Massart; J. Havel, J. Pazourek)

University of Tasmania, School of Chemistry, Australia (Prof. P. R. Haddad; J. Havel)

Ecole dÌngénieurs en Génie des Systémes Industriels, EIGSI, La Rochelle, France (Prof. J. A. Videau; J. Havel).

Universidad Autónoma de Barcelona, Bellaterra, Spain (Prof. M. Valiente; J. Havel).

Universidad de Barcelona, Barcelona, Spain (Prof. R. Tauler; J. Havel, P. Lubal).

Universidad National Autónoma de Mexico, UNAM, Mexico (Prof. A. Rojas-Hernández; J. Havel).

Universidad Autónoma de Mexico, UAM, Cuatitlán, Mexico (Prof. G. Pérez-Caballero; J. Havel).

Universidad Nacional de Cordoba, Facultad de Ciencias Químicas, Departamento de Fisicoquímica, Córdoba, Argentina (Prof. Carlos de Pauli; J. Havel).

Universidad de Salamanca, Department of Physical Chemistry, Salamanca, Spain (Prof. J. L. González; J. Havel, P. Lubal).

San José State University, California, U.S.A. (Prof. L. Yengoyan; J. Havel).

The Royal Institute of Technology, Department of Inorganic Chemistry, Stockholm, Sweden (Prof. I. Grenthe, Prof. M. Muhammed; J. Havel).

The R.W. Johnson Pharmaceutical Research Institute, Raritan, New Jersey, USA, (Dr. N. A. Guzman; J. Havel).

Dionex, Inc. U.S.A. (Dr. P. Jandik; J. Havel).

Eidgenossische Technische Hochschule, Department of Inorganic Chemistry, Zürich, Switzerland, (Prof. G. Anderegg; J. Havel; P. Lubal).

Universidad de Barcelona, Barcelona, Spain (Prof. R. Tauler; J. Havel, P. Lubal).

Barnett Institute, Northeastern University, Boston, USA (Prof. B. Karger, Prof. G. Davies; J. Preisler; J. Havel).

University of Ljubljana, Faculty of Chemistry and Chemical Technology, Ljubljana, Slovenia (Prof. Veber, M.; Komárek, J.).

Veterinary and Agrochemical Research Centre, Section of Ecochemistry and Spectroscopy, Tervuren, Belgium (Dr. Hoenig, M., Otruba, V).

Technical University Košice, Faculty of Metallurgy, Department of Chemistry, Košice, Slovak Republic (Prof. Krakovská, E., Otruba, V.).

Institut für Analytische Chemie, Abteilung Atomspektroskopie, Fakultät für Naturwissenschaften und Mathematik, Universität Wien, Österrich, Univ. (Prof. Dr. Steffan, I., Otruba, V.).

Adam Mickiewicz University, Department of Water and Soil Analysis, Poznan, Poland. (Prof. Dr. Siepak, Hab. J., Otruba, V.)

Departamento de Fisica, Universidad de Cordoba (Prof. Dr. Carmen Quintero Ortega, M., Otruba, V.).

Departamento de Química Analítica, Facultad de Estudios Superiores Cuautitlán, Universidad Autonoma de Mexico (Dr. Revilla Vazquez. A. L., Havel, J., Otruba, V.).

Lina Spark Applications, S.a., Cully, Switzerland (Dipl. Ing. Vogel, W., Otruba, V.).

Ben Gurion University of Negev, Israel (Dr. Brenner, I. (Joe), Otruba, V.).

Foreign visitors

Peña-Méndez, E. M., (Prof., Dr.), Universidad de La Laguna, Tenerife, Spain, visiting professor.

STUDENTS STUDYING ABROAD

Dohnal, V.: University of La Laguna, La Laguna, Tenerife, Spain, 5 months.

Muzikář, M.: University of Girona, Girona, Spain, 4 months.

Pilný, R.: Universidad de Barcelona, Spain, 4 months.

Hrdlička, A., Universidad de Córdoba, Spain, 3 months.

Studýnková, J.: Université Claude Bernard, France, 3 months.

Halúzka, M.: Université Claude Bernard, France, 3 months.

Vaculovič, T.: Université Claude Bernard, France, 3 months.

AWARDS

Šedo, O., Competition for the best student scientific work in analytical chemistry (MERCK), VŠCHT Prague, February 5- 6, 2002, the first prize.

Táborský, P.: Competition for the best student scientific work in analytical chemistry (MERCK), VŠCHT Prague, February 5- 6, 2002, the first prize.

Novotný, K., Studýnková, J., Machát, J., Semerád, M.: Young Chemist Competition (J. M. Marci Society), Prague, December 3, 2002, four 2nd –3th prizes.

OTHER PROFESSIONAL ACTIVITIES

Havel, J.:Head of the Department of Analytical Chemistry, Masaryk University; Member of the Editorial Board of Folia Fac. Sci. Nat. Masaryk. Univ.; Member of the International Society for Chemometrics; Member of the Working Party for Chemometrics of the Czech Chemical Society; Member of the Committee of the Regional Branch of the Czech Chemical Society; Member of the Spectroscopic Soc. of J. M. Marci, Prague; Member of the New York Academy of Sciences, Chairman of the Council for Doctorate Studies in Analytical Chemistry, the Masaryk University; Member of the Coucil for Doctorate Studies in Analytical Chemistry at Charles University in Prague, Member of the Council for Doctorate Studies in Analytical Chemistry at the College of Chemical Technology, Prague; Member of the Scientific Council of the Faculty of Sciences of the Masaryk University; Member of the Council for Doctorate Studies in Analytical Chemistry at Slovak Academy of Sciences, Bratislava, Slovak Republic, Member of International Geographic Society, Member of Americal Association for the Advancement of Science(AAAS).

Kanický, V.: Member of the Committee of the Spectroscopic Soc. of J. M. Marci, Prague; Vice-Chairman of the Working Party of Analytical Chemistry of the Czech Chemical Society; Member of the Committee of the Regional Branch of the Czech Chemical Society; Member of the Academic Senate of the Faculty of Sciences, Masaryk University; Member of the habilitation commission in analytical chemistry of the Faculty of Chemistry of the Technical University Brno; Deputy Head of the Laboratory of Plasma Sources for Chemical Analysis of the Faculty of Science, the Masaryk University Brno.

Komárek, J.: Deputy Head of the Department of Analytical Chemistry; Member of the Council for the Doctorate Study in Analytical Chemistry and Environmental Chemistry at the Masaryk University Brno.

Otruba, V.: Head of the Laboratory of Plasma Sources for Chemical Analysis.

Preisler, J.: Deputy Head of the Department of Analytical Chemistry.

Sommer, L.: Professor Emeritus, Member of the Working Party for Chemistry of the Commission for Accreditation of the Czech Government; Emeritus Member of the Commission for Analytical Reactions, Reagents and Separations, IUPAC; Member of the Council for Postgraduate Studies in Analytical Chemistry, the Masaryk University; Member of the Scientific Council of the College of Chem. Technology, Prague; Member of the Councils for Postgraduate Studies in Analytical Chemistry: Technical Univ. Prague and Palacký Univ. Olomouc; Member of the Working Party of Analytical Chemistry of the Czech Chemical Society; Member of the Spectroscopic Soc. of J. M. Marci, Prague; teaching at the Faculty of Chemistry of the Technical University Brno.

Department of Biochemistry


Department of Biochemistry arranged for teaching of the basic biochemical disciplines at the bachelor and master levels for students of chemistry, biology, and future high school teachers of our Faculty. In addition, specialized education of graduate students of biochemistry and some branches of biology (e.g., molecular biology) was carried out.

New students were accepted for graduate study. We guaranteed the teaching of 28 students in 4th and 5th year and 24 graduate students. The staff of the department participated in many national and international congresses. The department organized International Net Conference of Diploma Theses with participation of several Czech and Slovak Universities. Research activities are oriented to the topics studied in the following laboratories:

Laboratory of biochemistry of plant-pathogen interactions (V. Mikeš, J. Mazoch, V. Kratochvílová)

Laboratory of biosensors (P. Skládal)

Laboratory of environmental biotechnology (M. Mandl, O. Janiczek, H. Řičánková)

Laboratory of microbial bioenergetics (I. Kučera, P. Boublíková, Rotrekl, V., M. Kuňák, J. Neužilová)

Laboratory of separation of biomolecules (Z. Glatz, P. Zbořil, M. Wimmerová, L. Poláková)

Laboratory of proteom research (P. Bouchal, cooperation with the permanent staff)

Our research was supported almost exclusively by external sources: Grant Agency of the Czech Republic, Fund of the Development of Universities, research projects sponsored by foreign institutions, including the 5th Frame Program of the European Union and bilateral programs. The most of the research workers participated in Research Program of the Ministry of Education. Some research activities were carried out in cooperation with the Ministry of Health of the Czech Republic (animal biochemistry - S. Pavelka) and National Centre for Biomolecular Research (M. Wimmerová).

DEPARTMENT STAFF

Head: Vladimír Mikeš (Assoc. Prof., RNDr., CSc.) Professor: Igor Kučera (RNDr., D.Sc.) Associate Professors: Zdeněk Glatz (RNDr., CSc.) Martin Mandl (Ing., CSc.) Petr Skládal (RNDr., CSc.) Petr Zbořil (RNDr., CSc.) Assistant Professors: Pavla Boublíková (RNDr., CSc.) Oldřich Janiczek (RNDr., CSc.) Stanislav Pavelka (RNDr., CSc.), part time Vladimír Rotrekl (Mgr, Ph.D.) Michaela Wimmerová (RNDr., Ph.D.) Research Assistants: Pavel Bouchal (Mgr.) Šárka Helánová (Mgr.) Michal Kuňák (Mgr.) Jiří Mazoch (Mgr.) Ivo Pluháček (RNDr.) Technicians: Věra Kratochvílová Hedvika Řičánková Jitka Neužilová Ludmila Poláková Secretary: Stanislava Fousová Adjunct Lecturers:

Arnošt Kotyk (Prof., RNDr., D.Sc.), Institute of Physiology, Czech Academy of Sciences, Prague Petr Breinek (RNDr.), Faculty Hospital St. Anna, Brno Petr Pečínka (RNDr., CSc.), Institute of Biophysics, Czech Academy of Sciences, Brno Ph.D. Students: Full time Pavel Bouchal (Mgr.) Lenka Drábková (Mgr.) Gabriela Fanfrdlová (Mgr.) Jan Halámek (Mgr.) Šárka Helánová (Mgr.) Jan Lochamn (Mgr.) Andrea Kašná (Mgr.) Jitka Kašparovská (Mgr.) Tomáš Kašparovský (Mgr.) Michal Kuňák (Mgr.) Iva Navrátilová (Mgr.) Soňa Nováková (Mgr.) Petra Ševčíková (Mgr.) Renáta Solná (Mgr.) Jan Přibyl (Mgr.) Marta Zeisbergrová (Mgr.) Jiří Žeravík (Mgr.) Part time Iva Bartáková (Mgr.) Martina Budová (Mgr.) Ivana Huvarová (Mgr.) Nikola Kostlánová (Mgr.) Jiří Mazoch (Mgr.) Jana Sýkorová (Mgr.) Radek Tesařík (Mgr.)

THESES DEFENDED IN THE ACADEMIC YEAR 2001/2002

Diploma theses: Böhmová, G. Isolation of haem O and a study of its conversion to haem A by the enzymatic system of Paracoccus denitrificans (supervisor I. Kučera).

Budová, M. Expresion, purification and kinetic characterisation of haloalkan dehalogenases (supervisor M. Wimmerová).

Faltýsková, E.: Electrochemical studies on mitomicines and their interaction with DNA (supervisor L. Trnková).

Fohlerová, R. Measurement of intracellular pH in Paracoccus denitrificans cells (supervisor I. Kučera).

Gavlasová, P.: Inhibition of elemental sulfur oxidation by arsenic in Acidithiobacillus ferrooxidans (supervisor M. Mandl).

Koutská, K.O.: Tumour suppressor protein p53 binding to DNA (supervisor J. Paleček).

Lochman, J.: Identification of Armillaria by molecular biological methods and isoenzyme analysis (supervisor V. Mikes).

Měcháčková, V.: Reactive oxygen compounds (supervisor P. Zbořil).

Nálezková, M.: Structure determination of proteins using NMR (supervisor L. Žídek).

Novák, P.: Immunosensors for glycohemoglobin determination (supervisor P. Skládal).

Očadlíková, D.: The purification of glyoxalase I from bacterium P. denitrificans and yeast S. cerevisiae (supervisor P. Zbořil).

Petrlová, J.: Immunoassay of surfactants (supervisor M. Fránek).

Přibyl, J.: Studies on interactions of saccharides and glycoproteins with boric acid using piezoelectric biosensors (supervisor P. Skládal).

Šnajdrová, L.: Application of capillary electrophoresis for separation of bacterial cells (supervisor Z. Glatz).

Víteček, J.: Interaction of the elicitors from Armillaria with plant cells (supervisor V. Mikes).

Zeisbergrová, M.: Microchip capillary electrophoresis (supervisors V. Kahle, Z. Glatz).

Zelená, J.: Isolation and purification cytochrome c-dependent lactate dehydrogenase from yeast Saccharomyces cerevisiae (supervisor P. Zbořil).

Žeravčíková, B.: Sulfite dehydrogenase from Acidithiobacillus ferrooxidans (supervisor O. Janiczek).

Ph.D. thesis Friml, J.: Cell biology of polar auxin transport in Arabidopsis thaliana (supervisor P. Zbořil).

LIST OF PUBLICATIONS Books, book chapters and review articles MANDL, M., KUŠNIEROVÁ, M., TICHÝ, R., FEČKO, P. Biotechnologický výzkum sirných bakterií v Československu (Biotechnological research of sulfur bacteria in Czechoslovakia). In Kapitoly z historie československé mikrobiologie 2. p. 124-130, 2002.

Scientific papers

ČEŠKOVÁ, P., MANDL, M., HELÁNOVÁ, Š., KAŠPAROVSKÁ, J. Kinetic studies on elemental sulfur oxidation by Acidithiobacillus ferrooxidans: Sulfur limitation and activity of free and adsorbed bacteria. Biotechnology and Bioengineering, New York : Wiley, 78, 1, p. 24-30, 2002.

ČEŠKOVÁ, P., ŽÁK, Z., JOHNSON, B. D., JANICZEK, O., MANDL, M. Formation of Iodinin by a Strain of Acidithiobacillus ferrooxidans Grown on Elemental Sulfur. Folia Microbiologica, Prague : Czechoslovak Society for Microbiology, 47, 1, p. 78-80, 2002.

ČEŠKOVÁ, P., ŽÁK, Z., JOHNSON, B., JANICZEK, O., MANDL, M. Acidofilní chemolithoautotrofní bakterie oxidující síru tvoří iodinin (Acidophilic chemolithoautotrophic sulfur-oxidizing bacteria form iodinin). Chemické listy, Praha : Česká společnost chemická, 96, 6, p. 430-430, 2002.

DRÁBKOVÁ, L., JANICZEK, O., MANDL, M. Využití preparativní isoelektrické fokusace s imobilizovaným gradientem při purifikaci proteinů (The use of preparative isoelectric focusation with immobilized gradient for protein purification). Chemické listy, Praha : Česká společnost chemická, 96, 6, p. 427-428, 2002.

GLATZ, Z., ŠEVČÍKOVÁ, P. Monitoring of dithiothreitol clearance by means of micellar electrokinetic chromatography. Journal of Chromatography B, Amstredam : Elsevier Science, 770, 1-2, p. 237-241, 2002.

GLATZ, Z. Využití heterobifunkčních ligandů v afinitní chromatografio (Application of Heterobifunctional Ligands in Affinity Chromatography). Chemické Listy, Praha : Česká společnost chemická, 96, 3, p. 127-131, 2002.

HALÁMEK, J., MAKOWER, A., SKLÁDAL, P., SCHELLER, F. W. Highly sensitive detection of cocaine using a piezoelectric immunosensor. Biosensors & Bioelectronics, Oxford : Elsevier Advanced Technology, 17, 11, p. 1045-1050, 2002.

HELÁNOVÁ, Š., MANDL, M., GAVLASOVÁ, P. Bakteriální oxidace síry ve vztahu k mechanismu biodegradace pyritu (Bacterial oxidation of elemental sulfur in relation to the mechanism of pyrite biodegradation). Chemické listy, Praha : Česká společnost chemická, 96, 6, p. 489-489, 2002.

MANDL, M., ČEŠKOVÁ, P., HELÁNOVÁ, Š. Kinetické modely v biooxidaci síry (Kinetic models in elemental sulfur biooxidation). Chemické listy, Praha : Česká společnost chemická, 96, 6, p. 485-485, 2002.

MAZOCH, J., KUČERA, I. Control of Gene Expression by FNR-like Proteins in Facultatively Anaerobic Bacteria. Folia Microbiologica, Praha : Institute of Microbiology of AV ČR, 47 (2002), 2, p. 95-103.

MAZOCH, J., KUČERA, I. Detection, with a pH indicator, of bacterial mutants unable to denitrify. Journal of Microbiological Methods, Amsterdam : Elsevier Science B.V., 51, 1, p. 105-109, 2002.

MITCHELL, E., HOULES, C., SUDAKEVITZ, D., WIMMEROVÁ, M., GAUTIER, C., PÉREZ, S., WU, A. M. - Gilboa-Garber, Nechama - Imberty, Anne. Structural basis for oligosaccharide-mediated adhesion of

Pseudomonas aeruginosa in the lungs of cystic fibrosis patients. Nature Structural Biology, New York : Nature America Inc., 9, 12, p. 918-921, 2002.

NOVÁKOVÁ, S., GLATZ, Z. Determination of the kinetic parameters of rhodanese by electrophoretically mediated microanalysis in a partially filled capillary. Electrophoresis, Weinheim : VHC, 23, 7-8, p. 1063-1069, 2002.

PAVELKA, S., BABICKÝ, A., LENER, J., VOBECKÝ, M. Impact of high bromide intake in the rat dam on iodine transfer to the sucklings. Food Chem. Toxicol., Exeter, UK : Elsevier Science Ltd., 40, 7, p. 1041-1045, 2002.

PAVELKA, S., BABICKÝ, A., VOBECKÝ, M. Bromide affects transfer of iodine through mother's milk to rat sucklings. Chem. Listy, Praha : Česká společnost chemická, 96, 6, p. 431-431, 2002.

PAVELKA, S. Toxicological effects of bromide ion in the rat. Chem. Listy, Praha : Česká společnost chemická, 96, 6, p. 519-519, 2002.

PAVELKA, S., VOBECKÝ, M., BABICKÝ, A. Production and composition of rat mother's milk are influenced by excess bromide. Chem. Listy, Praha : Česká společnost chemická, 96, 6, p. 431-432, 2002.

SKLÁDAL, P., MOROZOVA, N. O., RESHETILOV, A. N. Amperometric biosensors for detection of phenol using chemically modified electrodes containing immobilized bacteria. Biosensors & Bioelectronics, Oxford : Elsevier Advanced Technology, 17, 10, p. 867-873, 2002.

ŠEVČÍKOVÁ, P., GLATZ, Z., SLANINA, J. Analysis of artichoke (Cynara cardunculus L.) extract by means of micellar electrokinetic capillary chromatography. Electrophoresis, Weinheim : VHC, 23, 2, p. 249-252, 2002.

ŠNAJDROVÁ, L., GLATZ, Z., ARMSTRONG, D.W. Separace bakteriálních buněk pomocí kapilární zónové elektroforézy (Separation of bacterie by capillary zone electrophoresis). Chemické Listy, Praha : Česká společnost chemická, 96, 6, p. 432-432, 2002.

ŠTĚRBOVÁ, H., ŠEVČÍKOVÁ, P., KVASNIČKOVÁ, L., GLATZ, Z., SLANINA, J. Determination of lignans in Schisandra chinensis using micellar electrokinetic capillary chromatography. Electrophoresis, Weinheim : VHC, 23, 2, p. 253-258, 2002.

WIMMEROVÁ, M., ZELINKOVÁ, N., COMBE, D., IMBERTY, A. Expression and purification of putative rhamnosyltransferase from Mycobacterium tuberculosis. Chemické listy, Praha : Česká společnost chemická, 96, 6, p. 433-433, 2002.


BOUCHAL, P., KUČERA, I. Analysis of membrane proteome of Paracoccus denitrificans by two-dimensional electrophoresis. In XVIII. biochemický zjazd. Zborník. p. 160-160, 2002.

BUHOT, N., MIKEŠ, V., PONCHET, M., DOULIEZ, J. Des élicitines de Phytophthora aux LTPs végétales (Elicitins of Phytophthora in vegetal LTPs). In Book of Abstracts of Quatriemes rencontres de Mycologie - Phytopathologie. p. 120-120, 2002.

DRÁBKOVÁ, L., JANICZEK, O., DAVIDOVÁ, I., MANDL, M. Oxidation of tetrathionate in Acidithiobacillus ferrooxidans. In Zborník, XVIII. biochemický zjazd. p. 116-116, 2002.

EL KHALED, Y., KAŠPAROVSKÁ, J., HLOUŠKOVÁ, R., MIKEŠ, V., ZVOLSKÝ, P., ŠERÝ, O. Využití metody HPLC pro detekci polymorfizmu TaqI A genu pro DRD2 (Using of HPLC method for the detection of TaqI A polymorphism of the DRD2 gene). In http://hema.uhkt.cz/forms/konfprs.sqw?P=1458. p. 1-1, 2002.

HELÁNOVÁ, Š., MANDL, M., ZEMAN, J. Iron- and sulfur-oxidizing activities of Acidithiobacillus ferrooxidans and their relation to the mechanism of pyrite biooxidation. In Zborník, XVIII. biochemický zjazd. p. 285-285, 2002.

JANICZEK, O., WIMMEROVÁ, M., KALETOVÁ, S. Sulfur Oxygenase from Acidithiobacillus ferrooxidans. In The 18th Biochemical Congress. p. 139-139, 2002.

KAŠPAROVSKÁ, J., HŘÍBKOVÁ, H., HLOUŠKOVÁ, R., HLADILOVÁ, R., NOVOTNÝ, M., ZVOLSKÝ, P., MIKEŠ, V., ŠIMEK, V., ŠERÝ, O. Ovlivňuje katechol-O-methyltransferasa dispozice k alkoholizmu? (Does catechol-O-methyltransferase influences dispositions to alcoholism?). In VI. Pracovní setkání biochemiků a molekulárních biologů. p. 15-16, 2002.

KAŠPAROVSKÝ, T., MIKEŠ, V., MILAT, M., BLEIN, J. Lipid elicitors of plant defense reaction (Lipid elicitors of plant defese reaction). In Book of Abstracts of 7th Meeting of WG. p. 74-74, 2002.

http://hema.uhkt.cz/forms/konfprs.sqw?P=1458

KAŠPAROVSKÝ, T., MIKEŠ, V., MILAT, M.-Louise. Signal pathway included in elicitation of tobacco cells with ergosterol. In Book of abstracts of 6th Meeting of biochemists and molecular biologists. p. 65-65, 2002.

KAŠPAROVSKÝ, T., MILAT, M., BLEIN, J., MIKEŠ, V. Ergosterol induces mobilization of internal calcium in tobacco cells. In Book of Abstracts, EFPP Congress, Prague. p. 91-91, 2002.

KVASNIČKOVÁ, L., ŠTĚRBOVÁ, H., ŠEVČÍKOVÁ, P., GLATZ, Z., KAHLE, V., SLANINA, J. Analysis of Lignans in Schisandra Extract, Comparison between CECand MEKC. In Book of abstracts of Developments in Chromatography and Electrophoresis & Chiranal 2002. p. 74-74.

KVASNIČKOVÁ, L., ŠTĚRBOVÁ, H., ŠEVČÍKOVÁ, P., GLATZ, Z., KAHLE, V., SLANINA, J. Analysis of Lignans in Schisandra Extract, Comparison between CECand MEKC. In proceeding of the 13th International Symposium on Capillary Electroseparation Techniques ITP 2002. p. 110-110.

LOCHMAN, J., ŠERÝ, O., JANKOVSKÝ, L., MIKEŠ, V. Discrimination of Armillaria species based on molecular-biological methods and HPLC.. In Book of Abstracts of 6th Meeting of Biochemists and Molecular Biologist. p. 72-72, 2002.

LOCHMAN, J., ŠERÝ, O., JANKOVSKÝ, L., MIKEŠ, V. Use of molecular-biological methods and HPLC for discrimination of Armillaria species in Czech Republic. In Book of Abstracts of the congress EFPP. p. 7-7, 2002.

LOCHMAN, J., ŠERÝ, O., MIKEŠ, V., JANKOVSKÝ, L. Discrimination of Armillaria species based on molecular biological methods and HPLC.. In Book of Abstracts of 7th Meeting of WG. p. 111-111, 2002.

MANDL, M., BARTÁKOVÁ, I., HELÁNOVÁ, Š. Sulfide mineral biodegradation and phytotoxicity of the resulting products. In 12th Int. Biodeterioration and Biodegradation Symp. p. 115-115, 2002.

MANDL, M., ČEŠKOVÁ, P., HELÁNOVÁ, Š., JANICZEK, O. Mechanism of elemental sulfur oxidation by acidophilic bacteria. In Zborník, XVIII. biochemický zjazd. p. 276-276, 2002.

NOVÁKOVÁ, S., TELNAROVÁ, M., GLATZ, Z. Electrophoretically Mediated Microanalysis of Rhodanese. In Book of abstracts of Developments in Chromatography and Electrophoresis & Chiranal 2002. p. 80-80.

NOVÁKOVÁ, S., TELNAROVÁ, M., GLATZ, Z. Electrophoretically mediated microanalysis of rhodanese. In Proceeding of the 13th International Symposium on Capillary Electroseparation Techniques ITP 2002. p. 75-75.

PAVELKA, S. A survey of effects of excessive bromide intake on iodine metabolism in the rat. In Macro and Trace Elements/Mengen- und Spurenelemente (Anke M., Muller R., Schafer U., Stoeppler M., eds.). p. 567-574, 2002.

PAVELKA, S., BABICKÝ, A., VOBECKÝ, M. Determination of the biological half-life of bromine in the rat in dependence on the physiological state of the animals. In Abstracts of the XVIII. Biochemický zjazd. p. 398-398, 2002.

PAVELKA, S., BABICKÝ, A., VOBECKÝ, M. Effects of a high bromide intake in the lactating rat. In Abstracts of the XVIII. Biochemický zjazd. p. xxx, 1 pp, 2002.

PAVELKA, S., BABICKÝ, A., VOBECKÝ, M. Effects of high bromide intake on various aspects of iodine metabolism in the rat. In Proceedings of the VIth Workshop of Biochemists and Molecular Biologists. p. 60-61, 2002.

PAVELKA, S., BABICKÝ, A., VOBECKÝ, M. High bromide intake in the lactating rat reduces transfer of iodine to the young and adversely affects their development. In Proceedings of the VIth Workshop of Biochemists and Molecular Biologists. p. 56-57, 2002.

PAVELKA, S. Excess bromide in the lactating rat is transferred through mother's milk to the suckling. In Macro and Trace Elements/Mengen- und Spurenelemente (Anke M., Muller R., Schafer U., Stoeppler M., eds.). p. 575-583, 2002.

PAVELKA, S. Exogenous bromide influences iodine metabolism in the rat. In Abstracts of the XVIII. Biochemický zjazd. p. xxx, 1 pp, 2002.

ŠEVČÍKOVÁ, P., GLATZ, Z. Monitornig of Cysteine in Human Urine by On-column Derivatization during MEKC. In Book of abstracts of Developments in Chromatography and Electrophoresis & Chiranal 2002. p. 84-84.

ŠEVČÍKOVÁ, P., GLATZ, Z. On-column derivatizace v kapilární zónové elektroforéze (On-column derivatization in CZE). In Book of abstracts of Developments in Chromatography and Electrophoresis & Chiranal 2002. p. 29-29.

ŠNAJDROVÁ, L., GLATZ, Z. Separation of bacterial cells by CZE. In XVIII. biochemický zjazd. Zborník. p. 369-369, 2002.

TESAŘÍK, R., MAZOCH, J., TURÁNEK, J., KUČERA, I. Purification and characterization of ferric reductases from Paracoccus denitrificans. In XVIII. BIOCHEMICKÝ ZJAZD. p. 150-150, 2002.

VADÁSZOVÁ, A., ZACHAŘOVÁ, G., ŘÍČNÝ, J., SMERDU, V., ASMUSSEN, G., PAVELKA, S., RAUCHOVÁ, H., SOUKUP, T. Muscle phenotype and thyroid hormones. Anatomical and biochemical data. In The First Multilateral Conference of the Physiologists from Central Europe (Štrbák V., Zahradník I., Križanová O., Zahradníková A., eds.). p. 76-76, 2002.

WIMMEROVÁ, M., BETTLER, E., IMBERTY, A. Glycosyltransferase Fold Recognition Analysis of the Mycobacterium Tuberculosis Genome Sequence. In XIV International Biophysics Congress, IUPAB. p. 58-58, 2002.

WIMMEROVÁ, M., BETTLER, E., IMBERTY, A. Glycosyltransferase prediction in Mycobacterium tuberculosis genome by threading. In 3rd International Symposium on Glycosyltransferases. p. 112-112, 2002.

WIMMEROVÁ, M., BETTLER, E., IMBERTY, A. Mycobacterial glycosyltransferases: fold recognition analysis of the Mycobacterium tuberculosis genome. In XIXčmes Journées de Chimie et Biochimie des Glucides. p. 65-65, 2002.

ZELINKOVÁ, N., WIMMEROVÁ, M., IMBERTY, A. Expression of putative mycobacterial glycosyltransferase Rv1526c. In The 18th Biochemical Congress. p. 118-118, 2002.

Other professional publications BOUCHAL, P., KUČERA, I. The effect of cultivation conditions on protein composition of membrane of Paracoccus denitrificans (The effect of cultivation conditions on protein composition of Paracoccus denitrificans membrane). In VI. Pracovní setkání biochemiků a molekulárních biologů. Sborník příspěvků. p. 67-67, 2002.

DADÁK, V., JANICZEK, O., VRÁNA, O. Cytochrome c forms complexes and is partly reduced at interaction with GPI-anchored phosphatase. BBA : Biochimica et biophysica acta : international journal of biochemistry and biophysics., Amsterdam : Elsevier, 2002, p. 9-17.

KUNAK, M., KUCERA, I. THE EFFECTS OF PH, TEMPERATURE, ELECTRON DONOR AND BIOMASS CONCENTRATION ON THE TIME COURSE OF NITRIC OXIDE CONCENTRATION IN THE DENITRIFICATION PATHWAY OF PARACOCCUS DENITRIFICANS. In sborník prispevku. p. 63-145, 2002.

KUŇÁK, M., KUČERA, I. Využití rekombinantního pseudoazurinu jako donoru elektronů nitritreduktasy s následným měřením dvouenzymové kinetiky (Utilization of recombinant pseudoazurin as an electron donor of nitrite reductase and follow-up measuring of dual enzymatic konetics.), 2002.

KUŇÁK, M., KUČERA, I. Utilization of recombinant pseudoazurin as an electron donor of nitrite reductase and follow-up measuring of dual enzymatic konetics.. In Zborník XVIII.Biochemický zjazd. p. 111-520, 2002.

MAZOCH, J., PROCHÁZKOVÁ, B., MIKEŠ, V. Enzymatic oxidation of glyoxylate by brown rot fungus Fomitopsis pinicola. In XVIII. BIOCHEMICKÝ ZJAZD. p. 127-127, 2002.

MIKEŠ, V., DOBEŠ, P., DAMBORSKÝ, J., BLEIN, J. Molecular mechanism of interactions of elicitors from Phytophtora with plant cells. In Zborník XVIII biochemického sjazdu. p. 192-192, 2002.

NOVÁKOVÁ, S., GLATZ, Z. Application of capillary zone electrophoresis for the study and assay of enzymes. In Book of abstracts of 6th Meeting of biochemists and molecular biologists. p. 77-77, 2002.

PŘIBYL, J., HALÁMEK, J., HEPEL, M., SKLÁDAL, P. Highly sensitive immunosensors for atrazine based on the direct and competitive assay procedures. In 9th International Meeting on Chemical Sensors. p. 261-261, 2002.

PŘIBYL, J., HEPEL, M., SKLÁDAL, P. Piezoelectric biosensors for polychlorinated biphenyls operating in aqueous and organic phases. In 9th International Meeting on Chemical Sensors. p. 408-408, 2002.

SKLÁDAL, P., HALÁMEK, J., SOLNÁ, R., KAŠNÁ, A. Development of multichannel electrochemical biosensors for environmental monitoring. In 2nd SENSPOL Workshop: Response to New Pollution Challenges. p. 30-30, 2002.

SKLÁDAL, P. Biosensores de armas biologicas săo destaque de hoje (Biosensors for detection of biological weapons), 2002.

SKLÁDAL, P., PŘIBYL, J., HEPEL, M., HORÁČEK, J. Piezoelectric immunosensors operating in organic phase: Simple measurement of hydrophobic pollutants. In 2nd SENSPOL Workshop: Response to New Pollution Challenges. p. 65-65, 2002.

ŠEVČÍKOVÁ, P., GLATZ, Z. Monitoring of DTT clearence by MEKC. In Book of abstracts of 6th Meeting of biochemists and molecular biologists. p. 53-53, 2002.

ŠEVČÍKOVÁ, P., GLATZ, Z. Monitoring of homocysteine in body fluids by means of MEKC and on-column reaction with 2,2-dipyridyldisulfide. In Proceeding of the 13th International Symposium on Capillary Electroseparation Techniques ITP 2002. p. 78-78.

ŠEVČÍKOVÁ, P., GLATZ, Z. Specific thiol determination by on-column derivatization during MEKC. In Book of abstracts of 6th Meeting of biochemists and molecular biologists. p. 75-75, 2002.

ŠNAJDROVÁ, L., GLATZ, Z., ARMSTRONG, D.W. Separace bakteriálních buněk pomocí kapilární zónové elektroforézy (Separation of bacterie by capillary zone electrophoresis). In Book of abstracts of 6th Meeting of biochemists and molecular biologists. p. 27-28, 2002.

ZELINKOVÁ, N., WIMMEROVÁ, M., IMBERTY, A. Glycosyltransferases from Mycobacterium tuberculosis. In The 6th Workshop of Biochemists and Molecular Biologists. p. 66-66, 2002.

CONFERENCES (SYMPOSIA, SEMINARS) ORGANIZED BY THE DEPARTMENT MEMBERS

Boublíková, P., Zbořil, P.: Member of the Organizing Committee, 6th Workshop of Biochemists and Molecular Biologists, Masaryk University, Brno, February 2002.

Janiczek, O., Mikeš, V., Zbořil, P., Mandl, M.: International Net Conference of Diploma Theses. Brno, Czech Republic, June 2002.

Skládal, P.: International meeting – EU project INTELLISENS -“Intelligent signal processing of biosensor arrays using pattern recognition for characterisation of wastewater: Aiming towards alarm systems“, Brno, Czech Republic, April 2002.

PROJECT GRANTS RECEIVED

Grant Agency of the Czech Republic 203/02/1447 Kahle, V., Gaš B. Glatz Z.: Capillary electrochromatography in monolytic polymer columns 203/01/1589 Kučera, I.: Mechanisms involved in regulation of respiratory systems in denitrification bacteria by environmental factors. 525/00/0785 Mandl, M.: Acidification processes in sulfide wastes. GA522/02/0925 Mikeš, V. Modeling of the structure and interactions of Phytophthora elicitors 203/00/P097 Rotrekl, V.: Identification of genes involved in nitrate transport in P.denitrificans and basic characterisation of their products.

Fund of the Development of Universities 740/2002 Bouchal, P.: Introduction of identification methods into analysis of bacterial proteome.

734/2002 Drábková, L., Janiczek, O: Oxidation of tetrathionate by Acidithiobacillus ferrooxidans.

725/2002 Helánová, Š., Mandl, M.: Bacterial oxidation of pyrite and elemental sulfur.

809/2002

Janiczek, O.: A new manuals, instructions and lectures for biochemistry students.

753/2002 Kašparovský T., Mikeš, V. Role of calcium in defense reaction of plants.

756/2002 Kuňák, M., Kučera, I.: Utilization of recombinant pseudoazurin as an electron donor of nitrite reductase

759/2002 Mazoch, J.: Interaction of elicitors from cell walls of Armillaria and their interaction with plant cells.

F 804/2002 Mikeš, V.: Innovation of practical course of Biochemistry.

766/2002 Nováková S.: Application of electrophoretically mediated microanalysis for the study of enzymes.

762/2002 Ševčíková P.: Development of new methods for the determination of homocysteine in human plasma

Foreign grants QLK3-2000-01481 Skládal, P. (local coordinator): Intelligent signal processing of biosensor arrays using pattern recognition for characterisation of wastewater: Aiming towards alarm systems – INTELLISENS (EU 5th Frame Program).

QLK3-CT-2001-00244 Skládal, P. (local coordinator): Novel in vitro testing platforms for extra- and intracellular sensing – CELLSENS (EU 5th Frame Program).

IHP-ARI-2002 Wimmerová, M.: Bioinformatics and chemometrics studies for the prediction of glycosyltransferases sequences within Mycobacterium tuberculosis genome. FP5. Improving Human Research Potential - Access to Research Infrastructures (European Comission).

MENRT No. 3 Wimmerová, M.: Glycosyltransferases of Mycobacterium tuberculosis. Postdoctoral grant (French Ministry of Science).

Other grants ME 598, Kontakt Mikeš, V.: Role of lipids in the elicitation of plant defense reaction (Czech Ministry of Education).

2002-042-1 Barrande Mikeš, V.: Structural and functional genomics of plant defense proteins (Czech Ministry of Education).

NJ/6109-3 Pavelka, S.: Interference of bromide from the environment with the metabolism of iodine in the thyroid and other tissues (Grant Agency of the Ministry of Health of the Czech Republic).

INVITED LECTURES AND RESEARCH STAYS OF STAFF ABROAD

Mikeš,V.: Laboratory of Plant Pathogen Interactions, INRA Antibes, France, 2 weeks.

Rotrekl, V.: Department of Molecular Medicine, Institute of Biotechnology, The University of Texas Health Science Center, San Antonio, USA, one year.

Skládal, P.: Visiting professor, Institute of Chemistry, UNESP, Araraquara, Brazil, Nov.- Dec. 2002 (FAPESP Fellowship).

Skládal, P.: Invited lecture, XIII Simposio Brasiliero di Electroquimica e Electroanalitica, Araraquara, Brazil, Dec. 2002 (CNPq Fellowship).

Wimmerová, M.: Centre de Recherches sur les Macromolécules Végétales (CERMAV), Molecular Glycobiology Group, Grenoble, France, two stays, 9 months and 3 weeks.

Wimmerová, M.: Invited lecture and FP5 project, LMC, The Royal Veterinary and Agricultural University, Food Technology, Copenhagen, Denmark, 1 week.

OTHER INTERNATIONAL CONTACTS AND CO-OPERATION OF THE STAFF

Cooperations

Department of Analytical Chemistry, Lund University, Lund, Sweden; Amperometric biosensors, flow-injection analysis, portable detectors (T. Ruzgas, J. Emnéus, P. Skládal).

Department of Bioanalytical Chemistry, Unversity of Potsdam, Potsdam, Germany; Piezoelectric biosensors, cholinesterase-based affinity sensors (A. Makower, F. Scheller, P. Skládal).

Department of Biotechnology, Lund University, Lund, Sweden; Cell-based microelectrodes, multichannel amperometric detectors (E. Csöregi, P. Skládal).

Department of Chemistry, State University of New York, Potsdam College, Potsdam, USA; Piezoelectric biosensors (M. Hepel, P. Skládal).

Catholic University Leuven, Pharmaceutical Faculty Laboratory of Pharmaceutical Chemistry Leuven, Belgium; Electrophoretically mediated microanalysis (A. Van Schapdael , Z. Glatz).

Centre de Recherches sur les Macromolécules Végétales (CERMAV), Molecular Glycobiology group, Grenoble, France; Proteins in carbohydrate synthesis and specific recognition (A. Imberty, N. Kostlánová, M. Wimmerová).

Department of Molecular Cell Physiology, Free University, Amsterdam, The Netherlands; Regulation of bacterial denitrification (R. van Spanning, I. Kučera).

Institut für Chemie, Universität für Bodenkultur, Wien, Austria; Eucaryotic fucosyltransferases (I.B.H. Wilson, M. Wimmerová).

Institute of Chemistry, Universidade Estadual Paulista, Araraquara, Brazil; Piezoelectric biosensors for nucleic acids (H. Yamanaka, P. Skládal).

LMC, The Royal Veterinary and Agricultural University, Food Technology, Copenhagen, Denmark; Bioinformatics and chemometric approaches in genome analysis (S.B.Engelsen, M. Wimmerová).

UMR INRA/Univesrite de Bourgogne, France, Project Barrande; Plant elicitors (J.-P. Blein, V. Mikeš).

School of Biological Sciences, University of Wales, Bangor, UK; Iodinin in sulfur-oxidizing bacteria (D.B. Johnson, M. Mandl).

Foreign visitors

Prof. P. Coutos, University of Poitiers, France, a visit to V. Mikeš, December 2002; Plant elicitors.

Dr. J.-P. Blein, UMR INRA/Univesrite de Bourgogne, France, a visit to V. Mikeš, December 2002; Plant elicitors.

Dr. E. Gomes, University of Poitiers, France, a visit to V. Mikeš, December 2002; Lecture: nsLTPs in plant defense mechanisms: facts and hypothesis.

Dr. K. Knösche, Department of Bioanalytical Chemistry, University of Potsdam, Potsdam, Germany, a visit to P. Skládal, November 2002; Piezoelectric biosensors.

Dr. I.B.H. Wilson, Institut für Chemie, Universität für Bodenkultur, Wien, Austria, a visit to M. Wimmerová, December 2002; Eucaryotic fucosyltransferase.


J. Halámek: Research stay at the Unviersity of Potsdam, Department of Analytical Biochemistry, Potsdam, Germany, 3 months.

J. Friml: Research stay at the University of Tuebingen, Germany, 6 months.

N. Kostlánová: Centre de Recherches sur les Macromolécules Végétales (CERMAV), 2 month (Fellowship of French Ambassy).

I. Navrátilová: Research stay at the National University of Ireland in Galway, Department of Physical Chemistry, Galway, Ireland, 1 month.

P. Novák: Research stay at the University of Potsdam, Department of Analytical Biochemistry, Potsdam, Germany, 1 month.

Nováková S.: Research stay at the Catholic University Leuven, Pharmaceutical Faculty P Laboratory of Pharmaceutical Chemistry Louvain, Belgium, 10 months.

R. Solná: Research stay at the Lund University, Department of Analytical Chemistry, Lund, Sweden, 6 month.

FOREIGN STUDENTS STUDYING AT THE DEPARTMENT

Kana Ito: Department of Chemistry, State University of New York, Potsdam College, Potsdam, USA (a visit to P. Skládal).

AWARDED STUDENTS AND STAFF

Pavelka, S.: Excess bromide in the lactating rat is transferred through mother’s milk to the suckling; Awarded as the best poster presented at the international symposium “Macro and Trace Elements/Mengen- und Spurenelemente”, held in Jena (Germany) on October 18-19, 2002.


Glatz Z.: Member of the Committee of Chromatography and electrophoresis group of the Czech Chemical Society, vice head of the Chemistry Section.

Janiczek. O.: Member of the Committee of the Agency of Fund for Development of Ministry of Education.

Mandl, M.: Member of the Committee of the Czech Biotechnological Society; Lectures on biotechnology, Faculty of Chemistry, University of Technology, Brno.

Mikeš, V.: Member of the Committee of the Czech Society for Biochemistry and Molecular Biology; Member of the Committee of the Agency of Fund for Development of Ministry of Education.

Wimmerová, M.: Member of the Brno Branch Committee of the Czech Chemical Society; Member of the Regional Committee of the Czech Chemistry Olympiad.

Zbořil, P.: Member of the Committee of the Agency of Fund for Development of Ministry of Education.

Department of Inorganic Chemistry


Teaching activities

The Department of Inorganic Chemistry provides education in the basic chemical disciplines, i.e. general and inorganic chemistry for students at the bachelor level, who major in chemistry, biology, geology and physics, as well as for chemistry teachers. Advanced inorganic chemistry lectures and courses at the master level are offered for students who major in inorganic chemistry. The Department also provides a basic course of nuclear chemistry and offers an advanced course in radioecology. A specialized laboratory course of inorganic chemistry students is offered to the students who major in inorganic chemistry. A new study program of Materials Chemistry was accredited by the Ministry of Education. It offers a two-year program leading to master degree in a modern and progressive chemical discipline. The curriculum involves courses in inorganic materials synthesis and characterization, material science of metals and alloys, and polymer chemistry. Courses “Multimedia in chemistry education “ were introduced. Instrumentation

The Department has an up-to-date X-ray structure laboratory. The four circle •-axis diffractometer KUMA KM-4 which is equipped with Oxford Cryosystem low-temperature device and CCD camera has been upgraded by installing a new X-ray source, 3kW X-ray tube + layered collimators, with enhanced brilliance. The low-temperature device enables a routine low temperature data collection and growing single crystals from liquids or liquefied gases and thus determine their solid state structure. A new P1-C40P Phoenix refrigerated circulator has been purchased for X-ray structure laboratory. Temperature of its large 12 l bath can be controlled to 0.01°C in the wide range from -40° C to 150° C.

An inert atmosphere glove box MBraun UNILAB allows handling of highly moisture and air sensitive materials. The moisture and O2 analyzers show that the inner nitrogen atmosphere of the box contains less than 1 ppm of water and oxygen. A new solvent trap was added to the system to remove organic vapors.

A programmable horizontal tube furnace allows heat treatment of samples up to 1250 °C under controlled atmosphere.

A laboratory of multimedia technologies was established. Research activities

The systematic study of the chemical reactivity of phosphorus(V) halogenide-oxides and their derivatives provided the following interesting results. The POCl3 in its reaction with 4-dimethylaminopyridine (DMAP) undergoes a base catalysed dismutation to PCl5 and DMAP.PO2Cl which in a successive reaction with DMAP yields [(DMAP)2PO2]Cl. It is a salt of a donor-stabilized cation [PO2]+, a hitherto unknown analogue of the nitronium ion, [NO2]+. A 31P NMR spectroscopic study of the reaction course enabled to suggest a likely reaction mechanism involving all observed species. The cation [DMAP.POCl2]+, a proposed product of the first reaction step, was also succesfully synthesized by a treatment of POCl3 with silylated DMAP.

An intensive work continued on the study of reactions of chlorodithiophoshoric acid pyridiniumbetaine, PyPS2Cl, with polyfunctional nucleophile reagents. Reactions of PyPS2Cl with thiosemicarbazide derivatives, phosphazenes and other nucleophiles were studied. A seriees of new heterocyclic compounds was prepared and characterized.

In the research area of inorganic materials chemistry, we prepared a series of cage aluminophosphonates and titanosilicates as organic-soluble molecular precursors. The reactions of these molecular building units with various reagents were studied with the aim of establishing reactivity patterns of their functional groups. The functionalized molecules will be assembled via non-aqueous sol-gel routes to form three-dimensional ordered networks. Resulting materials find applications as molecular sieves, adsorbents, and selective catalysts. A new non-aqueous sol-gel route to mixed oxide materials has been developed. It allows mixing of the components at a molecular level and provides materials with a high degree of homogeneity. These products are useful refractory, optical, and electronic materials. Mesoporous metallophosphate materials based on Al, Zr, La, Co, Cu, Cr, and Ni were prepared by a supramolecular templating route. Two gemini type surfactants were employed. Reactivity of alumazene was studied in reactions with phosphoric acid triesters, phosphonate diesters, sulphonic acid esters, nitriles, carbodiimides, and metal alkoxides. A novel aluminium amide-phosphate, amide-sulphonate, and nitrile adducts were isolated and spectroscopically and structurally characterized.

Selenium trioxide forms adducts with organic oxygen donors under suitable conditions. The donor-acceptor

complexes Et2O.SeO3 and (Me2O)2.SeO3 can be obtained as primary products in the reaction of selenium trioxide with dimethyl ether (Me2O) or diethyl ether (Et2O). The crystal and molecular structures of both complexes, that are stable only below their melting points, were determined by X-ray structure analysis. Conversion of these adducts to dialkylesters of diselenic and selenic acid in the liquid phase was monitored by Raman, 1H- and 77Se-NMR spectroscopy.

Two cyclic esters of selenic acid - C2H4O4Se and C2H2O8Se2.C4H8O2- were isolated from the dioxane/selenium trioxide system without using an inert solvent The donor-acceptor complex C4H8O2.SeO3 can be prepared in liquid sulfur dioxide only. If tetrachloromethane is used as an inert solvent, the solvates of triselenium heptoxide Se3O7.2C4H8O2 and Se3O7.3C4H8O2 were formed. All mentioned compounds were characterized by X-ray analysis and Raman spectroscopy.

The synthesis and spectroscopic characterisation of chalcogenophosphoryl ligands derived from pyridine have been introduced in our research activities. The synthesis was based on the oxidation of C5H3N(PPh2)2 by elementary sulfur and selenium, and hydrogen peroxide, respectively. The organic ligands act as tridentate, with both chalcogens and nitrogen involved in chelation. To extend the knowledge of the co-ordination chemistry of ligands (including structural investigations), a series of new compounds were isolated and structurally characterized.

Halogenides of imido-bis(sulfuric) acid and their salts have recently attracted an attention as perspective solutes in lithium batteries. The reactions of Cl3PNSO2Cl and its derivatives with various nucleophilic and electrophilic reagents lead to derivatives of imido-bis(sulfuric) acid and various polyheteroatomic cyclic molecules. Thus, we have prepared and structurally characterized several P-N-S-As and P-N-S-B heterocycles.

The study of cyclic halogenotriphosphazenes chemistry was concentrated on reactions of P3N3Cl6 and P3N3F6 with silyl amines, e.g. heptamethyldisilazane, and cyclic amines, e.g. piperidine, pyrrolidine. New, till now not published, compounds were detected by physicochemical methods.

Research activities of the radiochemical section of the Department focus on the use of radioactive tracers in the study of complex equilibria in solutions and in elucidation of the chemistry of solvent extraction of selected metal ions. Recent topics included the study of solvent extraction of Eu(III) and Am(III) from aqueous-organic media, and complexation of selected metals with humic acids. The radiochemical laboratory is also engaged in the determination of radon in the environment.

DEPARTMENT STAFF

Head: Josef Novosad ( RNDr., CSc., Associate Professor, since June 2002) Professors: Jiří Hála (RNDr., CSc.) Zdirad Žák, (RNDR., CSc.) Associate Professors: Jiří Pinkas (RNDr., Ph.D.) Jiří Příhoda (RNDr., CSc.) Jiří Toužín (RNDr., CSc.) Assistant Professors: Milan Alberti (RNDr., CSc.) Miloš Černík (RNDr., CSc.) Dalibor Dastych (RNDr., Dr.) Jiří Křivohlávek (Mgr., since June 2002) Aleš Mareček (RNDr., CSc.) Marek Nečas (Mgr., Ph.D.) Technicians: Světlana Filípková Helena Hřibová Aleš Mareček. Jr. - part time Zdena Michaličková Jiří Smola Alena Ševčíková Jiří Verner (ing.) – part time Secretary: Vladimíra Veselská Ph.D. Students: Full time

Martin Beran (Mgr.) Zuzana Brlejová (Mgr.) Markéta Chromá(Mgr.) Lenka Jablonská (Mgr.) Michal Janča (Mgr.) Jan Kratochvíl (Mgr.) Jiří Löbl (Mgr.) Lukáš Richtera (Mgr.) Valerie Richterová (Mgr.) Pavel Rovnaník (Mgr.) Radek Sluka (Mgr.) Richard Ševčík (Mgr.) Jan Taraba (Mgr.) Zbyněk Voráč (Mgr.) Radka Voznicová (Mgr.)

THESES DEFENDED PER ACADEMIC YEAR 2001/2002

Diploma theses:

J. Löbl: Study on the reactions of metal amides with esters and salts of phosphonic acids and silicon acetate. (supevisor: J. Pinkas) (in Czech).

R. Ševčík: Coordination chemistry of 2,6-bis(diphenylphosphino)pyridine. (supevisor: J. Novosad) (in Czech).

R. Voznicová: Reactions of hexachlorocyclotriphosphazene with silylating agents. (supevisor: M. Alberti) (in Czech).

Z. Voráč: Study of thermic behavior of halogenophosphazenes. (supevisor: M. Alberti) (in Czech).

PhD theses:

Janča, M.: Reaction on chlorodithiophoshoric acid pyridinium betaine with polyfunctioonal nucleophiles (supervisor: J. Příhoda) (in Czech)

LIST OF PUBLICATIONS Scientific papers

ČEŠKOVÁ, P., ŽÁK, Z., JOHNSON, B. D., JANICZEK, O., MANDL, M. Formation of Iodinin by a Strain of Acidithiobacillus ferrooxidans Grown on Elemental Sulfur. Folia Microbiologica, Prague : Czechoslovak Society for Microbiology, 47, 1, p. 78-80, 2002.

ČEŠKOVÁ, P., ŽÁK, Z., JOHNSON, B., JANICZEK, O., MANDL, M. Acidofilní chemolithoautotrofní bakterie oxidující síru tvoří iodinin (Acidophilic chemolithoautotrophic sulfur-oxidizing bacteria form iodinin). Chemické listy, Praha : Česká společnost chemická, 96, 6, p. 430-430, 2002.

JANČA, M., NEČAS, M., PŘÍHODA, J. Pyridinium 2-thioxo-2,3-dihydro-1H-naphtho[2,3-d]-1,3,2 5-diazaphosphole-2-thiolate. Acta Crystallographica Section E: Structure Reports Online, Chester, UK : IUCr, 2002, 58, p. 772-773.

JANČA, M., TARABA, J., PŘÍHODA, J. (4-tert-Butyl-2-methylthiosemicarbazido)(O-methyldithiophosphato)palladium(II). Acta Crystallographica Section E: Structure Reports Online, Chester, UK : IUCr, 2002, 58, p. 245-247.

JANICKIS, V., NEČAS, M., NOVOSAD, J., DUŠEK, M., PETŘÍČEK, V. Commensurate and incommensurate structures of the hexabromotellurate(IV) bis {dibromodiselenate(I)} ion - [(C2H5)(n)(C6H5)(4-n)P](2)[TeBr6(Se2Br2)(2)], n=0,1. Acta Crystallographica Section B-Structural Science, Denmark : BLACKWELL MUNKSGAARD, 58, 6, p. 977-985, 2002.

LIU, H. Z., CALHORDA, M. J., DREW, M. G. B., FELIX, V., NOVOSAD, J., VEIROS, L. F., DE BIANI, F. F., ZANELLO, P. New Cu(I) and Ag(I) binuclear complexes containing the dppa ligand. J. Chem. Soc., Dalton Trans., Velká Británie : The Royal Society of Chemistry, -, 23, p. 4365-4374, 2002.

MAN, S., KULHÁNEK, P., POTÁČEK, M., NEČAS, M. New fused heterocycles by combined intra-intermolecular criss-cross cycloaddition of nonsymmetrical azines. Tetrahedron Letters, Oxford : Pergamon - Elsevier Science, 36, 43, p. 6431-6433, 2002.

MAZAL, C., JONAS, J., ŽÁK, Z. Highly diastereoselective thermal decomposition of 3-(azidomethylene)dihydrofuran-2-one. Tetrahedron, Elsevier Science Ltd., 58, 14, p. 2729-2732, 2002.

NEČAS, M., DOSTÁL, J., SLAVÍK, J. (+)-Escholinine perchlorate. Acta Crystallographica Section E: Structure Reports Online, Chester, UK : IUCr, 58, 9, p. 1023-1024, 2002.

PINKAS, J., LÖBL, J., DASTYCH, D., NEČAS, M., ROESKY, H. W. Adamantane-Like Aluminum Amide-Phosphate from Alumazene. Inorg. Chem., Spojené státy americké : American Chemical Society, Washington DC, 41, 25, p. 6914-6918, 2002.

TOUŠEK, J., DOMMISSE, R., DOSTÁL, J., ŽÁK, Z., PIETERS, L., MAREK, R. Configurations and conformations of sanguinarine and chelerythrine free bases stereoisomers. Journal of Molecular Structure, UK : Elsevier, 613, 10, p. 103-113, 2002.

TOUŽÍN, J., NEPLECHOVÁ, K., ŽÁK, Z., ČERNÍK, M. Syntheses and Structures of Donor-Acceptor Complexes of Selenium Dioxide with Pyridine and Trimethylamine. Collection of Czechoslovak Chemical Communications, Prague : Imperie "Politika", 2002, 67, p. 577-586.

VERNER, J., POTÁČEK, M. CRISS-CROSS CYKLOADICE HNCO A HNCS NA 1,4-DIAZABUTA-1,3-DIENECH - METODA PŘÍPRAVY SUBSTITUOVANÝCH PERHYDROIMIDAZO[4,5-d]IMIDAZOLŮ (Criss-cross cycloaddition of HNCO and HNCS to 1,4-diaza-1,3-butadienes - method to preparation of substituted perhydroimidazo[4,5-d]imidazoles). Chemické Listy, Praha : Česká společnost chemická, 2002, 96, p. 394-394.

VERNER, J., TARABA, J., POTÁČEK, M. A new route to 1,4-disubstituted 5-thioxoperhydroimidazo[4,5-d]imidazol-2-ones . Tetrahedron, Oxford (UK) : Elsevier Science Ltd., 2002, 27, p. 4833-4836.


BERAN, M., PŘÍHODA, J. Studium reakcí halogenosírových kyselin s močovinou, kyselinou amidosírovou a látkami podobného typu (Reactions of halogenosulfucic acid with urea, amidosulfuric acid, and similar compounds). In Sborník příspěvků IV. semináře "Pokroky v anorganické chemii", Vranov u Brna, September 2002, pp. 18-19

BRLEJOVÁ, Z., PINKAS, J., KRATOCHVÍL, J., ROESKY, H. W. Příprava nových metalosilikátových sloučenin (Synthesis of new metallosilicate compounds). In Chemické listy. p. 359, 2002.

BRLEJOVÁ, Z., PINKAS, J., ROESKY, H. W. Preparation of Precursors for Metallosilicate and Metallophosphate Materials. In Sborník příspěvků IV. seminář „Pokroky v anorganické chemii“, Vranov u Brna, September 2002, pp. 23-24

ČERNÁK, J., PAHÁROVÁ, J., ŽÁK, Z., MAREK, J. CYANOCOMPLEXES WITH MULTI-N-DONOR LIGANDS. In 223rd ACS (=American Chemical Society) National Meeting. p. 63, 2002.

CHROMÁ, M., PINKAS, J., JANČÁLKOVÁ, I., ROESKY, H. W. Preparation of Mesoporous Metallophosphate Materials. In Sborník příspěvků IV. seminář „Pokroky v anorganické chemii“, Vranov u Brna, September 2002, pp. 35-36

CHROMÁ, M., PINKAS, J., ROESKY, H. W., JANČÁLKOVÁ, I. Příprava nových mezoporézních metalofosfátů (Synthesis of new mesoporous metallophosphates). In Chemické listy. p. 434, 2002.

JABLONSKÁ, L., NEČAS, M., PŘÍHODA, J. Reactions of thiophosphoric acid chlorides with diphenylthiourea. In Sborník příspěvků IV. semináře "Pokroky v anorganické chemii", Vranov u Brna, September 2002, p. 39-40

JANČA, M., PŘÍHODA, J. Reactions of chlorodithiophosphoric acid pyridinium betaine with polyfunctional nucleophiles. In Sborník příspěvků IV. semináře "Pokroky v anorganické chemii", Vranov u Brna, September 2002, pp. 39-40

KRATOCHVÍL, J., PINKAS, J. Příprava molekulárních a vrstevnatých hlinitofosfonátů (Preparation of Molecular and Layer Aluminophosphonates). In Sborník příspěvků IV. seminář „Pokroky v anorganické chemii“, Vranov u Brna, September 2002, pp. 43-44

PINKAS, J., LÖBL, J., ROESKY, H. W. Syntéza a charakterizace nových aminoaluminofosfátů (Synthesis and characterization of new aminoaluminophosphates). In Chemické listy. p. 378, 2002.

RICHTERA, L., TOUŽÍN, J. Reakce oxidu selenového s dialkylethery (The Reaction of Selenium Trioxide with Dialkyl Ethers). In Chemické listy. p. 357, 2002.

RICHTERA, L., TOUŽÍN, J. The Reaction of Selenium Trioxide with 1,4-Dioxane. In Sborník příspěvků IV. seminář „Pokroky v anorganické chemii“, Vranov u Brna, September 2002, pp. 56-57

ROVNANÍK, P., ČERNÍK, M. Donor-Stabilized Dioxophosphonium Cation: Synthesis, Hydrolysis and Crystal Structure of [(DMAP)2PO2]Cl.CH3CN. In Sborník příspěvků IV. seminář „Pokroky v anorganické chemii“, Vranov u Brna, September 2002, pp. 58-59

ROVNANÍK, P., ČERNÍK, M., ŽÁK, Z. Reakce pyridinových bazí s chloridem a bromidem fosforylu (Reactions of pyridine bases with phosphoryl chloride and bromide). In Chemické listy. p. 378, 2002.

SLUKA, R., ČERNÍK, M. Reakce hexachlorofosforečnanového aniontu s tetrafluoridem difosforylu (Reaction of hexachlorophosphate anion with diphosphoryl tetrafluoride). In Chemické listy. p. 380-380, 2002.

SLUKA, R., ČERNÍK, M. Synthesis and Chemical Properties of Halogenophosphates. In Sborník příspěvků IV. seminář „Pokroky v anorganické chemii“, Vranov u Brna, September 2002, pp. 60-61

VERNER, J., POTÁČEK, M. Criss-cross cycloaddition on 1,4-diazabuta-1,3-dienes. In Euroregionale Spring Symposium, List of Abstracts. p. 122, 2002.

Scientific lectures

PINKAS, J., BRLEJOVÁ, Z., LÖBL, J., KRATOCHVÍL, J., ROESKY, H. W. Synthesis and Functionalization of Molecular Building Blocks for Metallophosphates and -silicates, 2002.

Other professional publications KAPIČKA, L., ALEXOVÁ, V., DASTYCH, D. Analysis and Prediction of the 31P and 19F NMR Spectra of Cyclophosphazenes: Hexafluorocyclotriphosphazene (F2PN)3. In 3rd Workshop of Physical Chemists and Electrochemists. p. 30-30, 2002.

TOUŽÍN, J., NEPLECHOVÁ, K., ŽÁK, Z., ČERNÍK, M. Syntheses and Structures of Donor-Acceptor Complexes of Selenium Dioxide with Pyridine and Trimethylamine. Collect. Czech. Chem. Commun., Praha : Inst. Org. Chem. Biochem. ASCR, 2002, 67, p. 577-586, 10 pp.

VERNER, J., POTÁČEK, M., HAVEL, J. Novel Approach towards the Optimization of Organic Synteses Using Experimental Design,2 pp, 2002.


Research Project MSM 143100011 Žák, Z.: Structure, Bonding, Properties, and Analysis of Synthetic and Natural Molecular Ensembles.

Grant Agency of the Czech Republic 203/01/1533 Pinkas, J.: New Nonaqueous Routes to Phosphate, Silicate, Hybrid, and Oxide Materials.

Ministry of Education, Youth,and Sports of the Czech Republic Project No. 46 (Faculty of Science MU Brno) Příhoda J.: Integrated study of the specialization Conservator-restorator in the cooperation of study program Chemistry with social sciences

Project No. 45 (Faculty of Science MU Brno) Mareček, A.: Development of distance education in the Faculty of Science MU – the laboratory for multimedia and network support of education


Pinkas, J.: Institute of Inorganic Chemistry, Göttingen University, Germany, Socrates Program, lecture series on Materials Chemistry, 4 weeks (June 2002).

Příhoda, J.: School of Technology and Economics Dresden, Germany, 1 week (August 2002).

Alberti, M.: School of Technology and Economics Dresden, Germany, 1 week (August 2002).

Žák, Z.: University of Ljubljana, Slovenia, 2 weeks (May 2002)

Příhoda, J.: Humboldt University Berlin, Germany, 3 days (June 2002)

Příhoda, J.: School of Technology and Economics Dresden, Germany, Socrates Program, lecture series on

Methods in Chemical Laboratory (May 2002)

Novosad, J.: Department of Chemistry, University of Bergen, Norway, invited lecture „Coordination chemistry of P-X-P ligands“ (July 2002).


Foreign visitors Prof. Herrmann, E., School of Technology and Economics, Dresden, Germany, 6 days (July 2002).

Klose, J., School of Technology and Economics, Dresden, Germany, Socrates, 5 months, (March-July 2002).

Prof. Mori, H., Chubu University, Kasugai, Japan, 3 days (September 2002).

Cooperations

Department of Inorganic Chemistry, University of Göttingen, Germany, (Professor H. W. Roesky), Molecular Alumino- and Gallophosphates as Models of Zeolite Building Units and New Non-Aqueous Sol-Gel Routes to Oxide Materials (J. Pinkas).

Institute of Inorganic and Analytical Chemistry, Justus-Liebig-University of Giessen, Germany, (Professor M. Fröba), New Mesoporous Aluminophosphate Materials (J. Pinkas).

Department of Chemistry, University Jena, Germany, (Professor W. Plass), Synthesis, Structure, and Properties of Vanadosilicate and -phosphate Materials (J. Pinkas).

Department of Physical Engineering, Faculty of Mechanical Eng., Brno Technical University, Doc. RNDr. T. Šikola, CSc., „Formation of Nanostructures by Scanning Probe Microscope“ (J. Pinkas).

School of Technology and Economics, Dresden, Germany (Professor E. Herrmann) „Organophosphorus compounds and their complexes” (Z. Žák, J. Příhoda).

University of Wroclaw, Institute of Chemistry, Poland (Professor T.Glowiak), „Low temperature diffractometry” (Z. Žák).

University of Vienna, Institute of Inorganic Chemistry (Dr. P. Unfried) and Institute of Mineralogy and Crystallography (Dr. G. Giester), „Structures of rare earth metal compounds” (Z. Žák).

University of St Andrews, Department of Chemistry, St Andrews, UK (Prof. J.D. Woollins), „Coordination Chemistry of P-N Ligands“ (J. Novosad, M. Nečas).

University of Bergen, Department of Chemistry, Bergen, Norway (Prof. S. Husebye), „Studies of Structure, Coordination and Bonding in Tellurium Compounds“ (J. Novosad, M. Nečas).

Chubu University, Department of Applied Chemistry, Kasugai, Japan (Prof. M. Watanabe), „Chemistry of Polyphosphates“ (J. Novosad).

Kaunas University of Technology, Department of Chemical Technology, Kaunas, Lithuania (Prof. V. Janickis), „Chemistry of Polychalcogen Compounds“ (J. Novosad, M. Nečas).

Department of Chemistry and Biochemistry, Faculty of Science, University of Lisbon, Portugal (Prof. M.J. Calhorda), „New heterobimetallic and bifunctional molecular architectures“ (J. Novosad).


Jablonská, L.: School of Technology and Economics, Dresden, Germany, 2 months, (January-February 2002).

Kratochvíl, J.: Institute of Inorganic Chemistry, University of Göttingen, Germany, 3 months (February-April 2002).

Löbl, J.: Institute of Inorganic Chemistry, University of Göttingen, Germany, 3 months (October-December 2002).


Černík, M.: Member of Inorganic Chemistry Committee, Czech Chemical Society, Prague. Member of the Inorganic Chemistry Board of Examiners for Ph.D. study, Masaryk University, Brno.

Hála, J.: Associate member of the Commission V.8 (Solubility) of IUPAC. Member of the Inorganic Chemistry

Board of Examiners for Ph.D. study, Masaryk University, Brno. Member of the Nuclear Chemistry Board of Examiners for Ph.D. study, School of Nuclear Engineering, Technical University, Prague.

Novosad, J.: Member of Inorganic Chemistry Committee, Czech Chemical Society, Prague. Member of the Inorganic Chemistry Board of Examiners for Ph.D. study, Masaryk University, Brno.

Pinkas, J.: Member of the American Chemical Society. Member of the Chemistry Board, Grant Agency of the Czech Republic. Coordinator of the Socrates/Erasmus Program. Member of the Inorganic Chemistry Board of Examiners for Ph.D. study, Masaryk University, Brno.

Příhoda, J.: Member of the Inorganic Chemistry Board of Examiners for Ph.D. study, Masaryk University, Brno. Member of the Inorganic Chemistry Board of Examiners for Ph.D. study, Charles University, Prague. Coordinator of the Socrates/Erasmus Program, Head of the organizing Committee : 4th Meeting:” Progress in Inorganic Chemistry”, Vranov near Brno, September 2002

Toužín, J.: Member of the Inorganic Chemistry Board of Examiners for Ph.D. study, Masaryk University, Brno.

Žák, Z.: Member of the Inorganic Chemistry Board of Examiners for Ph.D. study, Masaryk University, Brno. Member of the Scientific Board of the Faculty of Sciences, MU Brno. Member of the Scientific Board of the Faculty of Chemistry, Technical University, Brno

Department of Organic Chemistry


The fundamental part of the education as well as research in the field of Organic chemistry is concentrated at the Department of Organic Chemistry with its Division of Macromolecular Chemistry.

TEACHING ACTIVITIES

The Department is responsible for teaching the organic chemistry, macromolecular chemistry, chemical technology, and related subjects. These disciplines are taught to students seeking a bachelor’s degree in chemistry (3 years Bc), master’s degree (5 years Mgr), as well as to students involved in the chemical education. Education is provided also for non-major students of biology and environmental science. The department makes a substantial contribution to the education of all specialists in organic, inorganic, physical and analytical chemistry, and biochemistry.

Undergraduate study

The primary focus of the Department is the education of the students having their major in organic and macromolecular chemistry. The usual study length is five years and it is completed with the student’s diploma thesis. The Master’s (Magister ”Mgr.”) degree is conferred after a successful completion of this program. The students are gaining knowledge and experience in all the theoretical and experimental chemistry disciplines including: synthesis, isolation, identification, and structural studies on chemical compounds using modern methods of analysis as well as knowledge in the application of computer assisted chemistry. Diploma thesis, its defense, and the state examination complete the program.

Graduate study

The department offers a program leading to the Ph.D. degree. The program usually takes three years. The students within this program, besides studying some new chemical disciplines, are teaching undergraduate programs in the laboratories and seminars and they are active members of the research groups having an access to all the research facilities available at the department, including NMR, UV - VIS and IR spectrometer instruments, GC, GC/MS and HPLC chromatography, microwave and ultrasound reactors, X-ray analysis and advanced computer technology. The study is completed following the successful defense of the doctoral thesis, and the final rigorous examination.

RESEARCH ORIENTATION

There are three basic orientations in research at the department: (1) synthetic organic chemistry focused on heterocyclic compounds, (2) physical organic chemistry, and (3) computer assisted organic chemistry in research of the structure and dynamic of biomolecules.

Synthetic Organic Chemistry

Heterocyclic Organic Chemistry

New methods of synthesis, cyclization reactions, and reaction mechanisms, reactivity of the new heterocyclic systems as well as their structure are studied. There are several research groups working in this area. One of the groups is concentrated on cyclization reactions leading to heterocyclic systems. Pericyclic reactions, their regio- and stereochemistry, especially 1,3- dipolar cycloadditions of ylides derived from quaternary isoquinoline derivatives, are investigated. The research efforts include special types of cycloadditions, so - called the ”criss-cross” cycloadditions, and very interesting transformations of this way prepared heterocycles. Some of the reactions, especially intramolecular varieties, are carried out under microwave initiation. Besides, the center of the interest are naturally occurring quaternary isoquinoline alkaloids in reactions with the nucleophiles and their other transformations. An application of organometallics on the preparation of new adamantane derivatives is upon investigation as well (M. Potáček, J. Dostál, M. Trávníček, J. Verner, R. Vícha, S. Man, J. Pospíšil).

The synthesis of substituted cyclic •-methylene lactones and their reactivity in nucleophilic vinylic substitution and 1,3-dipolar cycloaddition with respect of stereo and regioselectivity of these reactions are the fields of interest of the second research group (J. Jonas, C. Mazal, P. Melša, P. Bouzek). The chemistry of substituted bicyclo[1.1.1]pentanes aimed at the development of new synthetical methods for construction of rod-like molecules with various substitutional patterns (terminal and/or lateral) useful in the construction of larger molecular or supramolecular objects is a second area of interest of this group (C. Mazal, P. Bartoš, O. Škarka).

Another group (P. Pazdera, R. Čmelík, D. Fajkusová, J. Záletová and M. W. Fathalla) is interested in

synthesis, structure elucidation and reactivity studies on fused five, six, seven and eight membered heterocycles containing nitrogen atom and/or the sixth group elements. Heterocyclic skeletons are prepared by an application of aromatic or heterocyclic carboxylic and carbonic acid functional derivatives. This research group is concentrated also on the preparation of new heterocyclic compounds containing chalcogene-chalcogene bond by oxidative heterocyclization reactions. In some cases, the syntheses are carried out as the domino-processes. Other research interests lie on “green chemistry” techniques (such as applications of the phase transfer catalysis, ultrasound; one-pot, multi-component and domino-reactions, and search of new simple reagents for synthesis).

General multicomponent reactions are major interest of the Benovsky’s group, especially four component Ugi reaction and its stereoselective variations. The same group is also working on the project of stereoselective aza-annulation reactions as a synthetic tool for the fast and efficient construction of heterocycles.

The spectroscopy (FTIR, UV-VIS, NMR, MS) and X-ray analysis methods are used for the identification and structure elucidation. In some cases, applications of chemical ab initio (HF, DFT) calculations are done in a cooperation with the National Centre for Biomolecular Research.

Physical Organic Chemistry

Organic Photochemistry

The research activities of the group are concentrated in several areas. One is the study of photoinduced hydrogen and energy transfer in various systems. The reactions are studied by standard photokinetics as well as laser flash spectroscopy. The second area involves the study of various photochemical transformations, such as hydrogen abstraction or di-•-methane rearrangement, with a special interest in photochemical reactivity of organic compounds in aqueous solutions, ice, as well as in the solid state. The group is also involved in developing a completely new photochemical field – photochemistry in the microwave field. (P. Klán, M. Zabadal, D. Heger, J. Literák, R. Růžička)

NMR Spectroscopy

NMR spectroscopy of organic and bioorganic molecules is the field of interest of the NMR research group (R.Marek, P. Sečkářová, J. Toušek, O.Humpa). The research is focused on the study of alkaloids, purine analogues, and other nitrogen containing heterocycles. The tautomerism, protonation, and hydrogen bonding of purine analogues are investigated by using 15N NMR spectroscopy (solution and solid-state) and ab initio (DFT) approach. The research group is collaborating on these projects with several research groups (Antwerp, Jyväskylä, Olomouc, Prague, Szeged).

Computer assisted organic chemistry and molecular modeling

The research effort of the computer assisted organic chemistry group (J. Koča, M. Kratochvíl) is concentrated in three areas. The first is computer assisted organic synthesis using both topological and quantum chemistry methodology. Current attention is paid to reaction paths and transition states elucidation. The second field involves conformational studies on flexible molecules of a biological interest (pheromones, peptides, carbohydrates, nucleic acids). The third direction is focused on computer study of interactions and reactions of large biological polymers, especially proteins, with small substrates. This group has made an important contribution to information technology applications in chemistry.

Macromolecular chemistry

An integral part of the Department of Organic Chemistry is the Division of Macromolecular Chemistry (J. Sedlář, J. Petrůj, M. Potáček and Z. Salajka, L. Pospíšil). It seems to be a significant bridge for collaboration with the Polymer Institute of Brno and Faculty of Chemistry of the Technical University of Brno. The scientific interest of the Division is focused on olefin polymerization, polymer stability studies, and development of photostabilizers and composite materials. DEPARTMENT STAFF

Head: Milan Potáček (Prof., RNDr., CSc.) Professors: Jaroslav Jonas (RNDr., CSc.) Jaroslav Koča (RNDr., D.Sc.) Milan Kratochvíl (Ing., CSc.) – professor emeritus Albrecht Mannschreck (Prof. Dr.) – visiting professor

Associate Professors: Petr Klán (RNDr., Ph.D.) Pavel Pazdera (RNDr., CSc.) Jaroslav Petrůj (RNDr., CSc.) Assistant Professors: Petr Beňovský (RNDr., Ph.D.) Slávka Janků (RNDr., Ph.D.) – maternity leave Ctibor Mazal (RNDr., CSc.) Jiří Sedlář (Ing., CSc) - part time Richard Čmelík (Mgr.) – part time Petr Kulhánek (Mgr.) - part time Stanislav Man (Mgr.) - part time Ondřej Škarka (Mgr.) – part time Martin Trávníček (RNDr., Mgr.) – part time Jiří Verner (Ing.) - part time Robert Vícha (Mgr) - part time Miroslav Zabadal (Mgr.) -part time Teaching Assistant: Jitka Halvová (Ing.) Research Assistants: Radek Marek (RNDr., Ph.D.) Radovan Kareš (Mgr.) Hana Navrátilová (RNDr.) Technicians: Jiří Mikulášek Marek Poděl Česlav Ulrich Ing. Milan Bečka – from September 2002 Secretary: Milena Urbánková Librarian: Jana Foltýnová Adjunct Lecturers: Vladimír Kysilka (RNDr., CSc.) – Pliva - Lachema, a.s., Brno Jiří Matoušek (Prof., Ing., D.Sc.) Chemical Faculty, Technical University, Brno Karel Picka (RNDr.) Chemical Faculty, Technical University, Brno Jiří Pichler (Ing., CSc.) Antonín Sikora (Ing., CSc.) – Institute of Macromolecular Chemistry, Academy of Sciences,

Czech Republic Tomáš Veselý (Ing., CSc.) – Chemical Faculty, Technical University, Brno Ph.D. Students: Full time Kamil Antoš (Mgr.) Petr Bartoš (Mgr.) Luzuriaga Sharbel Eduardo (Mgr.) Michal Čajan (RNDr.) Richard Čmelík (Mgr.) Dagmar Fajkusová (Mgr.) Petr Kulhánek (RNDr.) Stanislav Man (RNDr.) Petr Melša (Mgr.) Martin Prokop (Mgr.)

Pavlína Sečkářová (Mgr.) Robert Skeřil (Mgr.) Ondřej Škarka (Mgr.) Zdeněk Vytiska (Mgr.) Martin Trávníček (RNDr.) Jiří Verner (Ing.) Zdeněk Vytiska (Mgr.) Robert Vícha (Mgr) Mohamed Walid Fathalla (M.Sc.) Miroslav Zabadal (Mgr.) Dominik Heger (Mgr.) Jaromír Literák (Mgr.) Jiří Pospíšil (Mgr.) Radovan Růžička (Mgr.) Part time Hana Navrátilová (RNDr.) Michal Kovář (Ing.)


Diploma theses Heger,D.: Photoinduced Triplet Energy Transfer in Flexible Bichromophores with Oligoester Tether. (Supervisor: P. Klán.)

Literák, J.: Microwave Photochemistry. (Supervisor: P. Klán.)

Palovský, L.: Catalysts for polymerization of 1-alkenes. Study of chemically modified supports for catalysts. (Supervisor: Z. Salajka.)

Pospíšil, J.: Intramolecular 1,3-dipolar cycloadditions of azomethine ylides initiated by microwaves. (Supervisor: M. Potáček.)

Růžička, R.: PCT in photochemistry. (Supervisor: P. Klán.)

Švarc, J.: Contribution to multimedial education of organic chemistry. (Supervisor: M. Potáček.)

Ph.D. theses Fathala, W. M., M.Sc..: The Regioselectivity in Reactions of Thioamides. (Supervisor: P. Pazdera.)

Trávníček, M., RNDr. : Selectivity in 1,3-Dipolar Cycloaddition Reactions of Azomethine Ylides. (Supervisor: M.Potáček.)

Navrátilová, H., RNDr. : trans – 4-(4-Fluorophenyl)-3-substituted-1-methylpiperidines. (Supervisor: M.Potáček.)

Čajan, M.: Some Anionic Complexes and Their Building Blocks (Supervisor: J. Koča)

RNDr. Theses Kulhánek, P.: Intra-intermolekulární criss-cross cykloadiční reakce. (Supervisor: M.Potáček.)

Man, S.: Reaction of berberine and coptisine with nucleophiles. (Supervisor: M.Potáček.)

Pospíšil, J.: Influence of N-substitution in carbamoyl stabilized azomethine ylides upon the stereoselectivity of 1,3-dipolar cycloaddition reactions. (Supervisor: M.Potáček.)

Habilitation

Klán P. : “Photoinduced Hydrogen Transfer by the Excited Carbonyl Group” (2002).


Books, book chapters and review articles KLÁN, P., CÍRKVA, V. Microwave Photochemistry. In Microwaves in Organic Synthesis, A. Loupy (Ed.). p. 463-486, 2002.

MAREK, R., LYČKA, A. 15N NMR Spectroscopy in Structural Analysis. Current Organic Chemistry, BR Hilversum : Bentham Science Publishers, 6, 1, p. 35-66, 2002.

Scientific papers

BOHÁČ, M., NAGATA, Y., PROKOP, Z., PROKOP, M., MONINCOVÁ, M., TSUDA, M., KOČA, J., DAMBORSKÝ, J. Halide-stabilizing residues of haloalkane dehalogenases studied by quantum mechanic calculations and site-directed mutagenesis. Biochemistry, 41, 48, p. 14272-14280, 2002.

BOUŘ, P., NAVRÁTILOVÁ, H., URBANOVÁ, M., SETNIČKA, V. (3R,4S)-4-(4-fluorophenyl)-3-hydroxymethyl-1-methylpiperidine: Conformation and structure monitoring by vibrational circular dichroism. Journal of Organic Chemistry, 67, 1, p. 161-168, 2002.

ČAJAN, M., LHOTÁK, P., LANG, J., DVOŘÁKOVÁ, H., STIBOR, I., KOČA, J. The conformational behaviour of thiacalix[4]arenes: the pinched cone/pinched cone transition. Journal of the chemical society. Perkin transactions II, Physical organic chemistry, London : Chemical society, 100, 1, p. 1922-1929, 2002.

ČMELÍK, R., MAREK, J., PAZDERA, P. A regioselectivity of electrophilic attacks to 5-amino-3-thioxo-3H-1,2-dithiole-4-carboxylic acid functional derivatives. An elucidation of product structures. Heterocyclic Communications, London : Freund Publishing House, 2002, 1, p. 55-60.

ČMELÍK, R., PAZDERA, P. Nové cesty transformace trithionů jako způsob přípravy heteropentalenů (New progress in Trithione Transformations as The Method for Heteropentalene Preparations). Chemické Listy, Prague : Česká společnost chemická, 96, 6, p. 393-393, 2002.

FAJKUSOVÁ, D., SCHANTL, J., PAZDERA, P. One-pot syntéza N-hydroxythiazolového a N-hydroxyimidazolového skeletu, studium jejich reaktivity (One-pot Synthesis of N-Hydroxythiazole and N-Hydroxyimidazole Skeleton, Study of Their Reactivity). Chemické Listy, Prague : Česká společnost chemická, 96, 6, p. 401-401, 2002.

FATHALLA, W., ČAJAN, M., MAREK, J., PAZDERA, P. Reactivity Study on Morpholine-1-carbothioic acid (2-phenyl-3H-quinazolin-4-ylidene) amide. Journal of Heterocyclic Chemistry, USA : HeteroCorporation, 2002, 39, p. 1145-1152.

FATHALLA, W., MAREK, J., PAZDERA, P. New Domino-Reaction for the Synthesis of N4-(5-Aryl-1,3-oxathiol-2-yliden)-2-phenylquinazolin-4-amines and 4-[4-Aryl-5-(2-phenylquinazolin-4-yl)-1,3-thiazol-2-yl]morpholine. Journal of Heterocyclic Chemistry, USA : HeteroCorporation, 2002, 39, p. 1139-1144.

FATHALLA, W., PAZDERA, P. The synthesis of new N3-aryl-N1-(2-phenylquinazolin-4-yl)thioureas. ARKIVOC, Florida : ARKAT-USA, 2002, 1, p. 7-11.

HULOVÁ, D., SEČKÁŘOVÁ, P., DOSTÁL, J., MAREK, R. Nefyziologické adukty kvartérních protoberberinových alkaloidů (Non physiological aducts of quarternary protoberberine alkaloids). Chemické listy, Praha : Česká chemická společnost, 96, 11, p. 944-944, 2002.

KLÁNOVÁ, J., KLÁN, P., NOSEK, J., HOLOUBEK, I. Fotochemie chlorfenolů v ledu (Photochemistry of chlorophenols in water ice). Chemické listy, Praha : Česká chemická společnost, 96, 6, p. 513-514, 2002.

KLÁN, P., HOLOUBEK, I. Ice (Photo)chemistry. Ice as a Medium for Long-Term (Photo)chemical Transformations - Environmental Implications. Chemosphere, Oxford, UK : Elsevier Science Ltd., 46, 8, p. 1201-1210, 2002.

KLÁN, P., PELLICCIOLI, A. P., POSPÍŠIL, T., WIRZ, J. 2,5-Dimethylphenacyl Esters: A Photoremovable Protecting Group for Phosphates and Sulfonic Acids. Photochemical and Photobiological Sciences, Cambridge, United Kingdom : Royal Society of Chemistry, 1, 11, p. 920-923, 2002.

KLÁN, P., RŮŽIČKA, R., HEGER, D., LITERÁK, J., KULHÁNEK, P., LOUPY, A. Temperature-sensitive photochemical aromatic substitution on 4-nitroanisole. Photochemical and Photobiological Sciences, Cambridge, United Kingdom : Royal Society of Chemistry, 1, 12, p. 1012-1017, 2002.

KOUTNÁ, P., DOSTÁL, J., TÁBORSKÁ, E., MAREK, R. Sanguinarin a chelerythrin v systému oktanol-voda (Sanguinarine and chelerythrine in octanol-water). Chemické listy, Praha : Česká společnost chemická, 96, 11, p. 943-944, 2002.

LITERÁK, J., KLÁN, P., HEGER, D., LOUPY, A. Photochemistry of Alkyl Aryl Ketones on Alumina, Silica-gel and Water-Ice Surfaces. Journal of Photochemistry and Photobiology A: Chemistry, Amsterdam, The Netherlands : Elsevier Science, 154, 2-3, p. 155-159, 2002.

MALIŇÁKOVÁ, K., DOSTÁL, J., TOUŠEK, J., MAREK, R. Struktura solí protopinových alkaloidů (The salts of protopine alkaloids). Chemické Listy, Praha : Česká společnost chemická, 96, 6, p. 405-406, 2002.

MAN, S., KULHÁNEK, P., POTÁČEK, M. Kombinované intra-intermolekulární criss-cross cykloadice allenylazinů (Combined intra-intermolecular criss-cross cycloadditions of allenylazines). Chem. listy, Praha : Česká společnost chemická, 96, 6, p. 404-404, 2002.

MAN, S., KULHÁNEK, P., POTÁČEK, M., NEČAS, M. New fused heterocycles by combined intra-intermolecular criss-cross cycloaddition of nonsymmetrical azines. Tetrahedron Letters, Oxford : Pergamon - Elsevier Science, 36, 43, p. 6431-6433, 2002.

MAREK, R. Strukturně-reaktivitní vztahy isochinolinových alkaloidů (Structure-reactivity relationships of isoquinoline alkaloids). Chem. Listy, Praha : Česká společnost chemická, 96, 11, p. 914-915, 2002.

MAREK, R., BRUS, J., TOUŠEK, J., KOVÁCS, L., HOCKOVÁ, D. N7- and N9-substituted purine derivatives: a 15N NMR study. Magnetic Resonance in Chemistry, West Sussex : John Wiley & Sons, Ltd., 40, 5, p. 353-360, 2002.

MAREK, R., DOSTÁL, J. Báze kvarterních isochinolinových alkaloidů a izolační artefakty (Bases of quaternary isoquinoline alkaloids and isolation artifacts). Chemické listy, Praha : Česká společnost chemická, 96, 4, p. 227-227, 2002.

MAREK, R., MAREK, J., DOSTÁL, J., TÁBORSKÁ, E., SLAVÍK, J., DOMMISSE, R. Isoquinoline alkaloids: a 15N NMR and x-ray study. Part 2. Magnetic Resonance in Chemistry, West Sussex : John Wiley & Sons, Ltd., 40, 11, p. 687-692, 2002.

MAZAL, C., JONAS, J., ŽÁK, Z. Highly diastereoselective thermal decomposition of 3-(azidomethylene)dihydrofuran-2-one. Tetrahedron, Elsevier Science Ltd., 58, 14, p. 2729-2732, 2002.

MELŠA, P., MAZAL, C. pi-Facial selectivity in 1,3-dipolar cycloaddition reactions of alpha-methylidene-gamma-lactone substituted by 4-methyl-2,6,7-trioxabicyclo[2.2.2]octanyl group in gamma-position. Collection of Czechoslovak Chemical Communications, Prague : Inst. Org. Chem. Biochem. Acad. Sci. CR, 67, 3, p. 353-364, 2002.

MOHAMED, W. F., MAREK, J., PAZDERA, P. Synthesis of New 4-(4-(4-Methoxyphenyl)-5-(2-phenylquinazolin-4-yl)-1,3-Thiazol-2-yl)morpholine and N4-(5-(4-Methoxyphenyl)-1,3-oxathiol-2-yliden)-(2-phenylquinazolin-4-yl)-amine. Heterocyclic Communications, London : Freund Publishing House, 2002, 1, p. 157-160.

MOHAMED, W. F., MAREK, J., PAZDERA, P. SYNTHESIS of 4-AMINO-3-CYANO-2-MORPHOLINOQUINOLINE. Heterocyclic Communications, London : Freund Publishing House, 2002, 1, p. 79-82.

MOHAMED, W. F., PAZDERA, P. Synthesis of Heterocyclic Skeletons by the Reaction of N1-(2-Cyanophenyl)-benzimidoyl Chloride with Thioamides. Molecules, Basel : MDPI, 96, 1, p. 557-564, 2002.

NAVRÁTILOVÁ, H., DE GELDER, R., KŘÍŽ, Z. Enantiodiscrimination in NMR spectra and X-ray structures of diastereomeric salts of trans-4-(4-fluorophenyl)-3-hydroxymethyl-1-methylpiperidine with (S)-Mosher acid. J. Chem. Soc. Perkin Trans. 2, Cambridge, U.K. : Royal Society of Chemistry, 2002, 12, p. 2093-2099.

OTYEPKA, M., KŘÍŽ, Z., KOČA, J. Dynamics and binding modes of free cdk2 and its two complexes with inhibitors studied by computer simulations. Journal of Biomolecular Structure & Dynamics, GUILDERLAND : ADENINE PRESS, 20, 2, p. 141-154, 2002.

PAZDERA, P., FATHALLA, W. Kineticky a termodynamicky kontrolovaný průběh domino reakce - Syntéza nových 1,3-oxathiolů a 1,3-thiazolů (Kinetically and Thermodynamically Controlled Domino-reaction - Synthesis of Novel 1,3-Oxathioles and 1,3-Thiazoles). Chemické Listy, Prague : Česká společnost chemická, 96, 6, p. 392-393, 2002.

PAZDERA, P., ŠIBOR, J., MAREK, J. Reakce v tuhé fázi - isomerace N-acylselenomočovin na N-acylisoselenomočoviny (Reaction in solid state - isomerization of N-acylselenoureas to N-acylisoselenoureas). Chemické Listy, Prague : Česká společnost chemická, 96, 6, p. 411-411, 2002.

POSPÍŠIL, J., POTÁČEK, M. Mikrovlnami iniciované intramolekulární 1,3-dipolární cycloadice azomethin ylidů (Intramolecular 1,3-dipolar cycloadditions initiated by microwaves). Chem. listy, Praha : Česká společnost chemická, 96, 6, p. 413-413, 2002.

POSPÍŠIL, J., TRÁVNÍČEK, M., POTÁČEK, M. Influence of N-Substituents of Carbamoyl-stabilized Azomethine Ylides in 1,3-Dipolar Cycloadditions. ARKIVOC, Florida : ARKAT-USA, 2001, (ii)p. 146-162, 2002.

RŮŽIČKA, R., ZABADAL, M., KLÁN, P. Photolysis of Phenacyl Esters in a Two-Phase System. Synthetic Communications, New York : Marcel Dekker, 32, 16, p. 2581-2590, 2002.

SEČKÁŘOVÁ, P., MAREK, R., DOSTÁL, J., DOMMISSE, R., ESMANS, E. L. Structural studies of benzophenanthridine alkaloid free bases by NMR spectroscopy. Magnetic Resonance in Chemistry, John Wiley & Sons, Ltd., 40, 2, p. 147-152, 2002.

ŠMEJKAL, K., SUCHÝ, V., VESELÁ, D., VANČO, J., MAREK, R. Izolace obsahových látek Paulownia tomentosa. Chem. Listy, Praha : Česká společnost chemická, 96, 11, p. 929-930, 2002.


TOUŠEK, J., MAREK, R., MALIŇÁKOVÁ, K., DOSTÁL, J. Kvantově chemické výpočty chemických posunů solí protopinových alkaloidů (Quantum chemical calculations of the chemical shifts of the salts of the protopine alkaloids). Chemické listy, Praha : Česká společnost chemická, 96, 11, p. 943-943, 2002.

TRÁVNÍČEK, M., POTÁČEK, M. Pyrrolidine and 1,3-oxazolidine formation from azomethine ylides influenced by change from classical conditions to microwave irradiation. ARKIVOC, Florida : ARKAT-USA, 2001, (V)p. 156-163, 2002.

VERNER, J., POTÁČEK, M. Criss-cross cykloadice HNCO a HNCS na 1,4-diazabuta-1,3-dienech - metoda přípravy substituovaných perhydroimidazo[4,5-d]imidazolů (Criss-cross cycloaddition of HNCO and HNCS to 1,4-diaza-1,3-butadienes - method to preparation of substituted perhydroimidazo[4,5-d]imidazoles). Chemické Listy, Praha : Česká společnost chemická, 2002, 96, p. 394-394.

VERNER, J., TARABA, J., POTÁČEK, M. A new route to 1,4-disubstituted 5-thioxoperhydroimidazo[4,5-d]imidazol-2-ones. Tetrahedron, Oxford (UK) : Elsevier Science Ltd., 2002, 27, p. 4833-4836.

VESELÁ, D., MAREK, R., UBIK, K., LUNEROVÁ, K., SKLENÁŘ, V., SUCHÝ, V. Dracophane, a metacyclophane derivative from the resin of Dracaena cinnabari Balf. Phytochemistry, Oxford : Pergamon - Elsevier Science Ltd., 61, 8, p. 967-970, 2002.

VÍCHA, R., POTÁČEK, M. Reakce Grignardových činidel s 1-adamantankarbonylchloridem pod lupou (Reactions of Grignard reagents with 1-adamantane carbonyl chloride under magnifier). Chemické listy, Praha : Česká chemická společnost, 96, 6, p. 419-420, 2002.

ZÁLETOVÁ, J., PAZDERA, P., DZURILLA, M., KUTSCHY, P., FEKIAČOVÁ, K. Syntéza a vlastnosti nových derivátů indolylbenzothiazolů (Synthesis and Properties of New Indolylbenzothiazole Derivatives). Chemické Listy, Prague : Česká společnost chemická, 96, 6, p. 421-422, 2002.


ADAM, V., FALTÝSKOVÁ, E., SOUKENÍKOVÁ, N., KIZEK, R., MAZAL, C., TRNKOVÁ, L. Voltammetrie 3-(azidomethylen)dihydrofuran-2-onu (Voltammetry of 3-(azidomethylene)dihydrofuran-2-one). In Sborník abstrakt III. pracovního setkání fyzikálních chemiků a elektrochemiků v Brně. p. 9-9, 2002.

BOUZEK, P., MAZAL, C. 3-(1,2,3-triazol-1-ylmethyliden)dihydrofuran-2-ony. Chem. Listy, Praha : Česká společnost chemická, 96, 6, p. 397-397, 2002.

DOLINOVÁ, J., KLÁN, P., HOLOUBEK, I. Photolysis of Aromatic Compounds in Water Ice Containing Hydrogen Peroxide. In SECOTOX, 7th Regional Meeting of the Central and Eastern European Section. p. 43-43, 2002.

DOLINOVÁ, J., KLÁN, P., HOLOUBEK, I. Photolysis of benzene and phenol in water ice containing hydrogen peroxide. In XIXth IUPAC Symposium on Photochemistry. p. 185-185, 2002.

DOLINOVÁ, J., KLÁN, P., HOLOUBEK, I. Photolysis of polycyclic aromatic compounds in water ice containing hydrogen peroxide. In SECOTOX East 2002, 7th Regional Meeting of the Central and Eastern European Section, Trends and Advances In Environmental Chemistry and Ecotoxicology, Book of Abstracts. p. 43-43.

DOLINOVÁ, J., KLÁN, P., KLÁNOVÁ, J., HOLOUBEK, I. Photolysis of benzene and phenol in water ice containing hydrogen peroxide. In XIXth IUPAC Symposium on Photochemistry. p. 185-185, 2002.

KLÁNOVÁ, J., KLÁN, P., HOLOUBEK, I. Photolysis and Radiolysis of Chlorophenols in Water Ice. In SECOTOX, 7th Regional Meeting of the Central and Eastern European Section. p. 48-48, 2002.

KLÁNOVÁ, J., KLÁN, P., NOSEK, J., HOLOUBEK, I. Photochemistry of chlorophenols in water ice. In XIXth IUPAC Symposium on Photochemistry. p. 288-288, 2002.

KLÁNOVÁ, J., KLÁN, P., NOSEK, J., HOLOUBEK, I. Photochemistry of chlorophenols in water. In SECOTOX East 2002, 7th Regional Meeting of the Central and Eastern European Section, Trends and Advances In Environmental Chemistry and Ecotoxicology, Book of Abstracts. p. 48-48.

KLÁN, P., KLÁNOVÁ, J., HOLOUBEK, I. Phototransformations of Organic Compounds in Water Ice. In SECOTOX, 7th Regional Meeting of the Central and Eastern European Section. p. 9-9, 2002.

KLÁN, P., LITERÁK, J., CÍRKVA, V., HÁJEK, M. Microwave Photochemistry. In XIXth IUPAC Symposium on Photochemistry. p. 70-71, 2002.

LITERÁK, J., KLÁN, P., HEGER, D. Molecular photochemical thermometer. In XIXth IUPAC Symposium on Photochemistry. p. 314-314, 2002.

MAN, S., KULHÁNEK, P., ZACHOVÁ, H., POTÁČEK, M. New Type of ortho-peri-fused Heterocycles via Combined Intra-intermolecular Cycloaddition. In 9th Blue Danube Symposium on Heterocyclic Chemistry, Book of Abstracts. p. 180-180, 2002.

MAREK, R., BRUS, J., TOUŠEK, J., KOVÁCS, L., HOCKOVÁ, D. 15N NMR study of N7- and N9-substituted purine derivatives. In 16th European Experimental Nuclear Magnetic Resonance Conference. p. PB129, 1 pp, 2002.

MAREK, R., MAREK, J., DOSTÁL, J., DOMMISSE, R. Isoquinoline alkaloids - an 15N NMR and X-ray study. In 9th Blue Danube Symposium on Heterocyclic Chemistry. p. 158-158, 2002.

MAZAL, C. Stereoselective reactions of alpha-methylene lactones. In 9th Blue Danube Symposium on Heterocyclic Chemistry, Book of Abstracts. p. 33-33, 2002.

MAZAL, C., ZABADAL, M., BOUZEK, P., STANDARA, S. Z-E Isomerization of 3-(X-methylene)dihydro-2(3H)-furanones. In ICPOC16, Structure and Mechanism in Organic Chemistry, 16th IUPAC Conference on Physical-Organic Chemistry, Book of Abstracts. p. PB32, 2002.

MELŠA, P., MAZAL, C. Stereoselective 1,3-Dipolar Cycloaddition of Azomethine Ylide to Substituted alfa-Methylene gamma-Butyrolactone. Chem. Listy, Praha : Česká společnost chemická, 96, 6, p. 406-406, 2002.

NAVRÁTILOVÁ, H., KAREŠ, R., POTÁČEK, M. Microwave-assisted Elimination Reaction on a Solid Support: Preparation of 4-(4-Fluorophenyl)-1-methyl-3-methylenepiperidine. In Book of abstracts, XXVIth Conference of Organic Chemists: New Trends in Organic Synthesis. p. PO14, 1 pp, 2002.

NAVRÁTILOVÁ, H., POTÁČEK, M. Trans-4-(4-fluorophenyl)-3-substituted-1-methylpiperidines: Chiral recognition and Transformations. In Book of Abstracts from the 14th International Symposium on Chirality. p. 91-91, 2002.

PAZDERA, P. Carbamoylation Reaction of Cyclic Ketones Promoted by s-l PTC and Ultrasound. In Book of abstracts, XXVIth Conference of Organic Chemists: New Trends in Organic Synthesis. p. PO 31, 1 pp, 2002.

PAZDERA, P., FATHALA, M. W., MAREK, J. Kinetically and Thermodynamically Controlled Domino-Reaction; Synthesis of Novel 1,3-Oxathioles and 1,3-Thiazoles. In 9th Blue Danube Symposium on Heterocyclic Chemistry, Book of Abstracts. p. 175-175, 2002.

PAZDERA, P. Synthesis of 1-Alkylated Benzouracils via Alkylation Reactions of 4-Methoxy-1,2-dihydroquinazolin-2-one Started by PTC and Ultrasound. In Book of abstracts, XXVIth Conference of Organic Chemists: New Trends in Organic Synthesis. p. PO 32, 1 pp, 2002.

POSPÍŠIL, J., POTÁČEK, M. Microwave-assisted solvent-free synthesis of hexahydrochromeno[4,3-b]pyrroles. In Euroregionale Spring Symposium, List of Abstracts. p. 117-117, 2002.

POSPÍŠIL, J., POTÁČEK, M. Mikrovlnami iniciované intramolekulární 1,3-dipolární cykloadice azomethin ylidů (1,3-Dipolar cycloadditions of azomethine ylides initiated by microwaves). In Štedentská vedecká konferencia, Zborník abstraktov prác. p. 19-19, 2002.

POSPÍŠIL, J., POTÁČEK, M. Solvent-free intramolecular 1,3-dipolar cycloadditions initiated by microwaves. In Book of abstracts, 6th Sigma-Aldrich Organic Synthesis Meeting. p. 49-49, 2002.

POSPÍŠIL, J., POTÁČEK, M. Synthesis of 1,2,3-Trisubstituted Imidazoline-4-ones in Microwaves under Solvent-free Conditions. In Book of Abstracts, XXVIth Conference of Organic Chemists, New Trends in Organic Chemistry. p. PO 35, 1 pp, 2002.

POSPÍŠIL, J., TRÁVNÍČEK, M., HUMPA, O., MANNSCHRECK, A., POTÁČEK, M. Search for Enantiomers in 1,3-Dipolar Cycloadducts by HPLC on Nonracemic Sorbents. In 9th Blue Danube Symposium on Heterocyclic Chemistry, Book of Abstracts. p. 157-157, 2002.

POTÁČEK, M., POSPÍŠIL, J. Microwave Irradiation - an Easy Route to Realization of Intramolecular 1,3-Dipolar Cycloadditions. In Book of abstracts, XXVIth Conference of Organic Chemists: New Trends in Organic Synthesis. 1. vyd. Bratislava - Publishing House of Slovak University of Technology, Book of abstracts. 2 pp, 2002.

POTÁČEK, M., POSPÍŠIL, J. 1,3-Dipolar Cycloadditions Activated by Microwaves in Solvent-free Medium. In Book of Abstracts, Innovative Methods and Techniques for Chemical Transformations. p. 44-44, 2002.

SEČKÁŘOVÁ, P., HULOVÁ, D., MAN, S., TOUŠEK, J., DOSTÁL, J., DOMMISSE, R., PIETERS, L., MAREK, R. O-Nucleophile Initiated Transformations of Berberine and Coptisine - an NMR Study. In Abstracts ANZMAG2002. p. 116-116.

SEČKÁŘOVÁ, P., HULOVÁ, D., MAREK, J., DOSTÁL, J., SKLENÁŘ, V., DOMMISSE, R., MAREK, R. Berberine and palmatine - the adventures of studying their derivatives. In 9th Blue Danube Symposium on Heterocyclic Chemistry. 1 pp, 2002.

STANDARA, S., ZABADAL, M., MAZAL, C. Studium Z-E izomerace (2-oxodihydrofuran-3-ylidenmethyl)etherů. Chem. Listy, Praha : Česká společnost chemická, 96, 6, p. 415-415, 2002.

TOUŠEK, J., MAREK, R., BRUS, J. Ab Initio Calculations and NMR Study of 15N Chemical Shielding Tensors of N7- and N9- Substituted Purine Derivatives. In International Chemometric Conference CHEMOMETRIC VI. p. 124-124, 2002.

TOUŠEK, J., MAREK, R., BRUS, J., KOVÁCS, L., HOCKOVÁ, D. Kvantově chemické výpočty tenzorů chemického stínění N7 a N9 substituovaných purinových derivátů (Quantum Chemical Calculations of the Chemical Shielding Tensors of N7 and N9 Substituted Purine Derivatives). In III. pracovní setkání fyzikálních chemiků a elektrochemiků - Sborník příspěvků. p. 44-44, 2002.

TRÁVNÍČEK, M., POSPÍŠIL, J., POTÁČEK, M. Stereochemistry determination of 1,3-dipolar cycloaddition products by NMR spectroscopy. In Central European NMR Discussion Groups, 17th NMR Valtice, Book of Abstracts. p. 12-12, 2002.

TRNKOVÁ, L., SOUKENÍKOVÁ, N., ADAM, V., MAZAL, C. Elektrochemické chování azidových sloučenin na rtuťových elektrodách (Electrochemical behaviour of azide compounds on mercury electrodes). In Sborník přednášek z XXII.celostátního semináře Moderní elektrochemické metody. p. 31-33, 2002.

VERNER, J., POTÁČEK, M. Criss-cross cycloaddition on 1,4-diazabuta-1,3-dienes. In Euroregionale Spring Symposium, List of Abstracts. p. 122-122, 2002.

VRBKA, L., KLÁN, P., KŘÍŽ, Z., KOČA, J. Conformational Behaviour of Flexible Molecules with Two Chromophores. In XLV Zjazd Naukowy Polskiego Towarzystwa Chemicznego. p. 1081-1081, 2002.

ZABADAL, M., POSPÍŠIL, T., PELLICCIOLI, A. P., KLÁN, P., WIRZ, J. 2,5-Dimethylphenacyl chromophore: Applications of a photoremovable protecting group. In XIXth IUPAC Symposium on Photochemistry. p. 519-519, 2002.

ZÁLETOVÁ, J., DZURILLA, M., KUTSCHY, P., PAZDERA, P. New Synthetic Methods for Preparation of Biological Active Indolylthiazoles and Indolylbenzothiazoles. In Book of abstracts, XXVIth Conference of Organic Chemists: New Trends in Organic Synthesis. p. PO 51, 1 pp, 2002.

Scientific lectures

BÁRTOVÁ, I., KŘÍŽ, Z., OTYEPKA, M., KOČA, J. Molecular Dynamics Simulations of CDK2/ATP Complex, 2002.

FADRNÁ, E., ŠPAČKOVÁ, N., ŠPONER, J., KOČA, J. Computer modelling of DNA quadruplex conformational behavior, 2002.

FADRNÁ, E., ŠPAČKOVÁ, N., ŠPONER, J., KOČA, J. DNA quadruplexes with lateral loops - molecular modelling study of conformational behavior, 2002.

FADRNÁ, E., ŠPAČKOVÁ, N., ŠPONER, J., KOČA, J. Molecular modelling of DNA fragment conformational behavior, 2002.

KŘÍŽ, Z., OTYEPKA, M., KOČA, J. Hydratace aktivniho mista enzymu CDK2. Studium pomoci molekulove dynamiky. (Hydration of the CDK2 active site. Molecular dynamics study.), 2002.

KŘÍŽ, Z., OTYEPKA, M., KOČA, J. Hydration of the CDK2 active site. Molecular dynamics study.

KŘÍŽ, Z., OTYEPKA, M., KOČA, J. Molecular Modeling of Peptides and Proteins at National Centre for Biomolecular Research (NCBR), 2002.

MAREK, R., LUKÁŠKOVÁ, M., TOUŠEK, J., BRUS, J., TRÁVNÍČEK, Z. Protonation and Tautomerism of 6-Benzylaminopurine Derivatives. In 17th NMR Valtice. p. 27-27, 2002.

OTYEPKA, M., STRNAD, M., DAMBORSKÝ, J., KŘÍŽ, Z., KOČA, J. Proteins and Their Interactions With Small Molecules Studied by Computer Simulations.

RÉBLOVÁ, K., ŠPAČKOVÁ, N., ŠTEFL, R., CSASZAR, K., KOČA, J., LEONTIS, N., ŠPONER, J. Molecular dynamics of the 5S rRNA loop E, 2002.

Other professional publications

DAMBORSKÝ, J., JESENSKÁ, A., PROKOP, Z., KMUNÍČEK, J., BOHÁČ, M., PROKOP, M., SÝKOROVÁ, J., CHALOUPKOVÁ, R., PAVLOVÁ, M., JEDLIČKA, T., MONINCOVÁ, M., STROUHAL, M., BUDOVÁ, M., KOČA, J., OTYEPKA, M., NAGATA, Y., WILCE, M. Protein engineering of dehalogenating enzymes. In Materials in Structure Chemistry, Biology, Physics and Technology. p. 34-34, 2002.

KULHÁNEK, P., KOČA, J. Influence of Water Molecule To Proton Transfer in Dipeptide Model. In International Chemometric Conference, CHEMOMETRICS VI. p. O20, 1 pp, 2002.

KULHÁNEK, P., KOČA, J. Kvantově-chemická studie přenosu protonu v oligopeptidech (Quantum-chemical Study of Proton Transfer in Oligopeptides). Chem. listy, Praha : Česká společnost chemická, 96, 6, p. 425-425, 2002.

VERNER, J., POTÁČEK, M., HAVEL, J. NOVEL APPROACH TOWARDS THE OPTIMIZATION OF ORGANIC SYNTHESES USING EXPERIMENTAL DESIGN. 2 pp, 2002.

Major popularisations and other professional publications BEŇOVSKÝ, P. : “Modern organic chemistry nomenclature”, lecture for high school teachers. Uherské Hradiště 2002.

BEŇOVSKÝ, P. : “Modern organic chemistry nomenclature”, lecture for high school teachers. Ostrava 2002.

BEŇOVSKÝ, P. : “Modern organic chemistry nomenclature”, lecture for high school teachers. Opava 2002.

JONAS J. : “ Chemie před a za zrcadlem”, Universita třetího věku, Brno, prosinec 2002.


Grant Agency of Ministry of Education COST D 10.20 / 2002 Potáček, M.: Microwave Activation in Organic Transformations. Fund of International Co-operation KONTAKT ME 571 MAZAL, C.: Substituované bicyklo[1.1.1]pentany a [n]staffany (NSF USA). Fund of the Development of Universities 758/2002 MAZAL, C.: Z-E Izomerace alfa-methylenlaktonů. 761/2002 MELŠA, P.: 1,3-Dipolární cykloadice alfa-methylenlaktonů.

Grant Agency of the Czech Republic 203/02/0879 Klán, P. - Vliv mikrovlnného záření na fotochemické reakce 205/02/0896 Klán, P., Holoubek, I.. - Fotochemie persistentních organických látek v ledu a na povrchu ledu a půd za různých klimatických podmínek 203/00/1011 Koča, J. – 2000-2002: Amidic ligands – design synthesis and complexes with anions (PI: Stibor, I., Institute of Chemical Technology, Prague).

203/01/1333 Pazdera, P.- Chalkogenorganic compounds – synthesis, structure and reactivity study AWARDS

Radek Marek – Alfred Bader Prize in Bioorganic chemistry: Structure-reactivity relationships in isoquinoline alkaloids, 2002.

CONFERENCES (SYMPOSIA, SEMINARS) ORGANIZED BY THE DEPARTMENT STAFF MEMBERS

Klán, P.: tajemník organizačního výboru (secretary) - 54. Sjezd chemických společností, Masarykova univerzita Brno, 2002.

Potáček, M.: Member of the Scientific Committee - 9th Blue Danube Symposium on Heterocyclic Chemistry, June 16 - 20, 2002. Tatranská Lomnica, Slovakia.

Potáček, M.: Member of the Organizing Committee – The joint Meeting of the Czech and Slovak Chemical Society, June 30 – July 4, 2002. Brno. Czech Republic.

Marek, R.: Member of the Organizing Committee – The joint Meeting of the Czech and Slovak Chemical Society, June 30 – July 4, 2002. Brno. Czech Republic.

Marek, R.: Member of the Organizing Committee – Meeting of the Central European NMR Discussion Groups, April, 2002. Valtice. Czech Republic

Mazal, C.: Member of the Organizing Committee – The joint Meeting of the Czech and Slovak Chemical Society, June 30 – July 4, 2002. Brno. Czech Republic.

Koča J.: Chairman of the Organizing Committee – The joint Meeting of the Czech and Slovak Chemical Society, June 30 – July 4, 2002. Brno


Stays

Klán P.: Norwegian Institute for Air Research; Ny-Ålesund, Svalbard, Norway (10 days)

Koča J.: CERMAV, Grenoble, France (visiting professor, 3 months)

Marek, R.: University of Antwerp, Belgium (1 moths)

Marek, R.: University of Szeged, Hungary (4 days)

Mazal, C.: University of Colorado at Boulder, USA (3 months)

Pazdera, P.: University of Innsbruck, Austria (visiting professor, 4 days)

Invited Lectures

Klán P., Klánová J., Holoubek I. „Fototransformace organických látek v ledu“ 37. Konference - Pokroky v organické, bioorganické a farmaceutické chemii, Nymburk, Czech Republic, 2002.

Klán P., Klánová J., Holoubek I. „Photochemical Fate of Organic Compounds in Water Ice“, Workshop on Ocean-Sea Ice-Snowpack-Atmosphere Interactions Research, Purdue University, Lafayette, IN, USA, 2002.

Klán P., Klánová J., Holoubek I. „Phototransformations of Organic Compounds in Water Ice“ SECOTOX, 7th Regional Meeting of the Central and Eastern European Section, Brno, Czech Republic, 2002.

Marek R. „Strukturně-reaktivitní vztahy isochinolinových alkaloidů“ 37. Konference - Pokroky v organické, bioorganické a farmaceutické chemii, Nymburk, Czech Republic, 2002.

Marek R. „Structure-reactivity relationships of isoquinoline alkaloids“ Hungarian Academy of Sciences, Szeged, Hungary, 2002.

Marek R., Dostál J.: “Báze kvarterních isochinolinových alkaloidů a izolační artefakty”. Mezioborová konference mladých chemiků a biologů Sigma-Aldrich, Velké Meziříčí, Czech Republic 2002.

Marek R.: “Izolační artefakty palmatinu a berberinu”. Přednáškové odpoledne České společnosti chemické a České biologické společnosti, Masarykova Univerzita, Brno, 2002.

Pazdera, P.: Domino Reactions and Synthesis of Nitrogen Heterocycles, Innsbruck University, Institut of Organic Chemistry, Innsbruck, Austria, June 07, 2002.

Mazal, C. „Naše první zkušenost s rychlou plynovou chromatografií“. Fast GC. 23. května 2002, Brno.

Mazal, C. Stereoselective reactions of •-methylene lactones. 9th Blue Danube Symposium on Heterocyclic Chemistry. June 16-20, 2002, Tatranská Lomnica, Slovensko.

Beňovský, P.: Stereoselective aza-annulation reactions. Institut für Organische Chemie, Universität Regensburg, Germany.

Potáček, M.: The Role of Microwaves in Organic Synthesis. Nankai University, Tienjin, China.


Lectures

Prof. Dr.Josef Michl, University of Colorado, Boulder, USA, lecture: The Chemistry of Carborane Anions and Radicals.

Prof. Dr. Armin Geyer, Institut für Organische Chemie, Universität Regensburg, Germany, lecture: Synthesis and Spectroscopic Characterization of Novel Peptide Secondary Structures.

Prof. Dr. Joachim G. Schantl, Institut für Organische Chemie, Universität Innsbruck, Austria lecture: Diazene – Derived Azomethine Imines.

Ing. Daniel Horák, CSc., Institute of Macromolecular Chemistry, Academy of Science, Prague, lecture: Synthetic and Natural Hydrogels as Carriers of Biologically Active Compounds for Medicine and Biology.

Prof. Dr. Jacek Mlochowski, Institute of Organic Chemistry, Biochemistry and Biotechnology, Wroclaw University of Technology, Poland, lecture: Recent Development in the Synthesis of new Bioactive Selenium Containing Heterocycles.

Prof. Dr. Fernando Langa, Faculty of Science,Universidad de Castilla-La Mancha, Toledo, Spain: lecture: Synthesis and Profrperties of Electroactive Fullerene Derivatives.

Prof. Dr. Uroš Urleb, University of Ljubljana, Slovenia, lecture: Design, Synthesis and Biological Activity of Thrombin Inhibitors with an Azaphenylalanine Scaffold.

Prof. Dr. Chris Strauss, Centre for Green Chemistry, School of Chemistry, Monash University, Victoria, Australia, lecture: Green, Thermal Organic Chemistry

Prof. Jakob Wirz, Institut für Physikalische Chemie, Universität Basel, Switzerland, lecture: Bringing light to dark reactions, lecture course: A crash course on laser flash photolysis.

Dr. Lajos Kovács, Department of Medicinal Chemistry, University of Szeged, Hungary, lecture: Regioselective substitution of guanine.

Cooperation

Prof. Dr. Albrecht Mannschreck, Institut für Organische Chemie, Universität Regensburg, Germany, Enantiomeric separations. (M. Potáček,).

Dr. André Loupy, Université Paris – Sud, Institut de Chemie Moleculaire d’Orsay, Laboratoire des Reactions sur Supports, France. Microwave Assisted Organic Synthesis (M. Potáček, P.Klán).

Dr. Lajos Kovács, University of Szeged, Hungary, N7/N9 – Guanine Derivatives (R. Marek).

Prof. Erkki Kolehmainen, University of Jyväskylä, Finland, NMR of Purine Analogues (R. Marek).

Prof. Roger Dommisse, Prof. Luc Pieters, University of Antwerp, Belgium, Structural Studies of Alkaloids (R. Marek)

Prof. Dr. Wolf-Diethard Pfeiffer, Institut für Chemie, Universität Greifswald, Germany, Synthesis of Organic Selenium Compounds (P. Pazdera).

Prof. Dr. Peter Kutschy, Prof. Dr. Milan Dzurilla, Department of Organic Chemistry, P. J. Šafárik University, Košice, Slovak Republic, Synthesis of phytoalexin analogues (P. Pazdera).

Prof. Dr. Jacek Mlochowski, Institute of Organic Chemistry, Biochemistry and Biotechnology, Wroclaw University of Technology, Poland, Synthesis of 2-Aminoselenophenole and its Synthetic Applications (P. Pazdera).

Prof. Dr. Joachim Schantl, Institute of Organic Chemistry, Innsbruck University, Austria, One-pot synthesis of some thiazoles and imidazole derivatives.

Dr. Walid Fathalla Mohamed, Suez Canal University, Faculty of Engineering, Port Said, Egypt. Synthesis of quinazoline derivatives by domino-reactions.

Prof. Josef Michl, University of Colorado, Boulder, CO, U.S.A., Synthesis of bicyclo[1.1.1]pentane derivatives (C. Mazal).

Prof. Jakob Wirz, Institut für Physikalische Chemie, Switzerland: Laser flash photolysis of phenacyl chromophores (P. Klán).

Dr. Anne Imberty, CERMAV Grenoble, France: Structural studies in carbohydrate chemistry (J. Koča).


Hana Zachová, Universität Regensburg, Institut für Organische Chemie, Germany – 4 months.

Martina Rozsypalová, Universität Regensburg, Institut für Organische Chemie, Germany – 4 months.

Luboš Vrbka, University of Missouri, USA- 2 months.

Tomáš Pospíšil, University of Missouri, USA- 2 months.

Veronika Trávníčková, Universita Degli Studi di Palermo, Italy – 3 months.

Lenka Baráková, University of Antwerp, Belgium – 4 months.

Pavlína Sečkářová, Mgr., University of Jyväskylä, Finland – 4 months.

Radovan Růžička, Mgr., University of Jyväskylä, Finland – 4 months.

Dagmar Fajkusová, Mgr., Universität Innsbruck, Institut für Organische Chemie, Germany – 3 months.

Jiří Pospíšil Mgr., Université Catolique, Louvain-la-Neuve, Belgium – 3 months

Miroslav Zabadal, Mgr., Universität Regensburg, Institut für Organische Chemie, Germany – 3 months.

Kamil Antoš, Mgr., Universität Regensburg, Institut für Organische Chemie, Germany – 4 months.

Petr Bartoš, Mgr., University of Colorado, Boulder, USA – 6 months.

STAYS OF FOREIGN STUDENTS AT DEPARTMENT

Mgr. Jana Záletová, Department of Organic Chemistry, P. J. Šafárik University, Košice, Slovak Republic, Syntheses of Compounds with Indol-3-yl Benzothiazole Skeleton – 5 months (Supervisor: P. Pazdera).

Luisanna Antonina Caradona, Universita Degli Studi di Palermo, Italy – 3 months (Superviser: M.Potáček, S.Man).

Dr. Walid Fathalla Mohamed, Suez Canal University, Faculty of Engineering, Port Said, Egypt. Synthesis of Quinazoline Derivatives by Domino-reactions. Post-doc-stay – 2 months (Supervisor: P. Pazdera).

STUDENT AWARDS

Ing. Jiří Verner – Geldpreis vom Fonds der Chemischen Industrie für herausragende Posterpräsentation, Euroregionale 2002, JCF Symposium, Aachen March 13 – 15,2002.

Jaromír Literák, Mgr., Masaryk University Rector Prize, 2002.

Jiří Pospíšil, Mgr., Faculty of Science Dean Prize, 2002.


Potáček M.: Chairman: Chemical Section, Chemical Section Scientific Board and Organic Chemistry Scientific Board at Masaryk University, Member of Organic Chemistry Scientific Board at Charles University of Prague, Prague Institute of Technology and Palacky University of Olomouc, Member of the State Examination Committee at Prague Institute of Technology, Palacky University Olomouc, University of Pardubice and Technical University of Brno, Faculty of Chemistry.

Pazdera, P.: Vice-chairman of Faculty Senate. Member of Czech Universities Council. Member of Commission for Defences of Ph.D. Thesis, Department of Organic Chemistry, Prague Institute of Technology, University of Pardubice and Slovak Technical University, Bratislava, Member of Habilitation Commision, Faculty of Chemistry, University of Pardubice.

Beňovský, P. : Member of the Group for Organic, Bioorganic and Pharmaceutical Chemistry, the Czech Chemical Society.

Koča, J.: member of the scientific board of Faculty of informatics, chairman of the Brno branch of the Czech chemical society, member of the American chemical society, member of the government accredit board in chemistry, doctoral study board (organic chemistry, physical chemistry, environmental chemistry, biomolecular chemistry, biophysics).

Department of Theoretical and Physical Chemistry


The Department of Theoretical and Physical Chemistry at the Faculty of Science continued to contribute substantially to the education of future chemists in the field of physical chemistry (about 60 students per year), future teachers of chemistry (about 30 students per year), future biologists and ecologists (about 60 students per year) as well as to research activity in the fields of theoretical and physical chemistry.

Pedagogical efforts involved fundamental lectures on physical chemistry, including quantum chemistry and chemical constitution and specialized courses in electrochemistry, chemical kinetics, quantum chemistry, spectroscopy (NMR, EPR, MS), phase equilibria, statistical thermodynamics and irreversible processes including extensive laboratory courses at undergraduate and postgraduate levels.

The research activity of the department concerned the study of the chemical and electrochemical reactivity of chemical substances and the relation to their structure through the use of different experimental and theoretical methods of physical chemistry. Reactions provided by electron transfer have been studied by means of electrochemical methods. New method of electrochemical signal processing and electrochemical methods with simultaneous membrane introduction mass spectrometry and with simultaneous electron paramagnetic resonance have been designed. Phase equilibrium and diffusion studies in metallic systems have been performed in collaboration with the Institute of Physics of Materials, Academy of Sciences of the Czech Republic, electrochemistry of nucleic acids and proteins are performed in collaboration with the Institute of Biophysics, Academy of Sciences of the Czech Republic. The spatial structure of biological macromolecules and biomacromolecular dynamics is studied by means of high field NMR in solutions. In addition this department studies other physico-chemical properties of molecules (surface tension, viscosity, conductivity, etc.) in relation to their molecular structure using computer simulations and molecular modeling.

DEPARTMENT STAFF

Head: Jan Vřešťál (Prof., RNDr., D.Sc.) Professors: Miroslav Holík (RNDr., CSc.) Vladimír Sklenář (RNDr., D.Sc.) Associate Professors: Pavel Janderka (RNDr., CSc.) Pavel Kubáček (RNDr., CSc.) Marie Studničková (RNDr., CSc.) – till September 2002 Libuše Trnková (RNDr., CSc.) Assistant Professors: Pavel Brož (RNDr., Ph.D.) Jiří Sopoušek (RNDr., CSc.) Jaromír Toušek (RNDr., Ph.D.) Technicians: František Macourek Dana Tesařová Secretary: Marta Holíková Adjunct Lecturers: Michal Roth (Assoc. Prof., RNDr., CSc.), Inst. Anal. Chem. Acad. Sci. CR Brno Jiří Čermák (RNDr., CSc.) Inst. of Physics of Materials Acad.Sci. CR Brno Ph.D. Students: Full time Iveta Bártová (Mgr.) Eva Drbálková (Mgr.) Miroslava Filgasová (Ing.) Klára Hladečková (Mgr.) Jana Houserová (Mgr.) Radka Chaloupková (Mgr.) Josef Chmelík (Mgr.) Květuše Chvátalová (Ing.)

Libor Kapička (Mgr.) Jan Kmuníček (Mgr.) Hana Křížová (Mgr.) Karel Kubíček (Mgr.) Barbora Láňová (Mgr.) Eva Lichnerová (Ing.) Michaela Matějková (Mgr.) Natálie Musilová- Sedláčková (Mgr.) Radim Picha (Mgr.) Filip Rázga (Ing.) Radka Vařeková (Mgr.) Martin Zeman (Mgr.) Part time Petr Kovařík (Mgr.) Lukáš Králík (Ing.) Petr Padrta (Mgr.) Vladimír Proks (Mgr.) Věra Rothová (RNDr.)


Diploma theses:

Chmelík, J.: NMR and Molecular Dynamics: Tools for Structural Studies of Proteins (supervisor: V.Sklenář) (in English) Ph.D.theses:

Houserová, J.: First principles studies of ordered structures in systems of transition metals (supervisor: J.Vřešťál) (in English)

Padrta, P.: Analysis of NMR Data for Structure Elucidation of Nucleic Acids (supervisor: V Sklenář) (in English)


Books, book chapters and review articles

FIALA, R., SKLENÁŘ, V. NMR of Nucleic Acids. In Zerbe, Oliver. BioNMR in Drug Research. p. 121-145, 2002.

Scientific papers

BROŽ, P., BURŠÍK, J., PICHA, R. Theoretical and Experimental Study of the gamma and gamma' Eqilibrium in the Ni-Al-Cr-Co System. Intermetallics, Netherlands : Elsevier, 10, 6, p. 635-639, 2002.

BROŽ, P., BURŠÍK, J., SVOBODA, M., KROUPA, A. Theoretical and experimental study of the gamma and gamma' equilibrium in Ni-based Superalloys. Materials Science and Engineering, Netherlands : Elsevier, 324A, 1-2, p. 28-33, 2002.

BROŽ, P., SVOBODA, M., BURŠÍK, J., KROUPA, A., HAVRÁNKOVÁ, J. Theoretical and experimental study of the influence of Cr on the gamma + gamma' phase field boundary in the Ni-Al-Cr system. Materials Science and Engineering, Netherland : Elsevier, 325A, 1-2, p. 59-65, 2002.

HOUSEROVÁ, J., FRIÁK, M., ŠOB, M., VŘEŠŤÁL, J. Ab initio calculations of lattice stability of sigma-phase and phase diagram in the Cr-Fe system. Computational Materials Science, Oxford : Elsevier Science, 2002, 4, p. 562-569.

HOUSEROVÁ, J., VŘEŠŤÁL, J., FRIÁK, M., ŠOB, M. Phase diagram calculation in Co-Cr system using ab initio determined lattice instability of sigma phase. CALPHAD-COMPUTER COUPLING OF PHASE DIAGRAMS AND THERMOCHEMISTRY, OXFORD : PERGAMON-ELSEVIER SCIENCE LTD, 26, 4, p. 513-522, 10 pp, 2002.

JANDERKA, P., DRBÁLKOVÁ, E., VŘEŠŤÁL, J. Užití membránového vstupu hmotnostního spektrometru v elektrochemii (Use of membrane inlet of mass spectrometer in electrochemisty). Chemické Listy, Praha : ČSCH, 96, 2, p. 103-110, 2002.

KIZEK, R., TRNKOVÁ, L., ŠEVČÍKOVÁ, S., ŠMARDA, J., JELEN, F. Silver Electrode as a Sensor for Determination of Zinc in Cell Cultivation Medium. Analytical Biochemistry, San Diego : Academic Press, 301, 1, p. 8-13, 2002.

LÁŇOVÁ, B., VŘEŠŤÁL, J. Study of Bray-Liebhafsky Reaction by On-Line Mass Spectrometry. Journal of Physical Chemistry A, USA : ACS, 106, 7, p. 1228-1232, 2002.

MALIŇÁKOVÁ, K., DOSTÁL, J., TOUŠEK, J., MAREK, R. Struktura solí protopinových alkaloidů (The salts of protopine alkaloids). Chemické Listy, Praha : Česká společnost chemická, 96, 6, p. 405-406, 2002.

MAREK, R., BRUS, J., TOUŠEK, J., KOVÁCS, L., HOCKOVÁ, D. N7- and N9-substituted purine derivatives: a 15N NMR study. Magnetic Resonance in Chemistry, West Sussex : John Wiley & Sons, Ltd., 40, 5, p. 353-360, 2002.

MUNZAROVÁ, M., SKLENÁŘ, V. Three-Bond Sugar-Base Couplings in Purine versus Pyrimidine Nucleosides: A DFT Study of Karplus Relationships for 3JC2/4-H1' and 3JC6/8-H1' in DNA. Journal of the American Chemical Society, Washington, D.C. : American Chemical Society, 124, 36, p. 10666-10667, 2002.

PADRTA, P., SKLENÁŘ, V. Program MULDER - A tool for extracting torsion angles from NMR data. Journal of Biomolecular NMR, Dordrecht : Kluwer/Escom, 24, 4, p. 339-349, 2002.

PADRTA, P., ŠTEFL, R., KRÁLÍK, L., ŽÍDEK, L., SKLENÁŘ, V. Refinement of d(GCGAAGC) hairpin structure using one- and two-bond residual dipolar couplings. Journal of Biomolecular NMR, Dordrecht : Kluwer/Escom, 24, 1, p. 1-14, 2002.

SYCHROVSKÝ, V., VACEK, J., HOBZA, P., ŽÍDEK, L., SKLENÁŘ, V., CREMER, D. Exploring the Structure of a DNA Hairpin with the Help of NMR Spin-spin Coupling Constants:An Experimental and Quantum Chemical Investigation. Journal of Physical Chemistry B, USA : The American Chemical Society, 106, 29, p. 10242-10250, 2002.


TOUŠEK, J., MAREK, R., MALIŇÁKOVÁ, K., DOSTÁL, J. Kvantově chemické výpočty chemických posunů solí protopinových alkaloidů (Quantum chemical calculations of the chemical shifts of the salts of the protopine alkaloids). Chemické listy, Praha : Česká společnost chemická, 96, 11, p. 943-943, 2002.

TRANTÍREK, L., ŠTEFL, R., MASSE, J., FEIGON, J., SKLENÁŘ, V. Determination of the glycosidic torsion angels in uniformly C-13 labeled nucleic acids from vicinal coupling constants 3J(C2/4-H1') and 3J(C6/8-H1'). Journal of Biomolecular NMR, Dordrecht : Kluwer/Escom, 23, 1, p. 1-12, 2002.

TRNKOVÁ, L. Electrochemical behavior of DNA at a silver electrode studied by cyclic and elimination voltammetry. Talanta, The Netherlands : Elsevier Science, 56, p. 887-894, 2002.

TRNKOVÁ, L., KIZEK, R., DRAČKA, O. Elimination Voltammetry of Nucleic Acids on Silver Electrodes. Bioelectrochemistry, The Netherlands : Elsevier, 55, p. 131-133, 2002.

TRNKOVÁ, L., KIZEK, R., VACEK, J. Catalytic Signal of Rabbit Liver Metallothionein on a Mercury Electrode:A Combination of Derivative Chronopotentiometry with Adsorptive Transfer Stripping. Bioelectrochemistry, The Netherlands : Elsevier, 3, 56, p. 57-61, 2002.

VESELÁ, D., MAREK, R., UBIK, K., LUNEROVÁ, K., SKLENÁŘ, V., SUCHÝ, V. Dracophane, a metacyclophane derivative from the resin of Dracaena cinnabari Balf. Phytochemistry, Oxford : Pergamon - Elsevier Science Ltd., 61, 8, p. 967-970, 2002.


ADAM, V., FALTÝSKOVÁ, E., SOUKENÍKOVÁ, N., KIZEK, R., MAZAL, C., TRNKOVÁ, L. Voltammetrie 3-(azidomethylen)dihydrofuran-2-onu (Voltammetry of 3-(azidomethylene)dihydrofuran-2-one). In Sborník abstrakt III. pracovního setkání fyzikálních chemiků a elektrochemiků, p. 9-9, 2002.

BRÁZDOVÁ, M., KIZEK, R., VACEK, J., TRNKOVÁ, L. Stanovení glutathion-S-transferasy na pevných elektrodách (Determination of glutathion-S-transferase on solid electrodes). In Sborník abstrakt III. pracovního setkání fyzikálních chemiků a elektrochemiků, p. 14-14, 2002.

BROŽ, P., BURŠÍK, J., SOPOUŠEK, J., PICHA, R. Simulated Element Redistribution in Ni-based Superalloy Weldment. In Procedings of the VIII Seminar Diffusion and Themodynamics of Materials. p. 95-98, 2002.

DRBÁLKOVÁ, E., JANDERKA, P., LOEFFLER, T. The DEMS study of electrochemical dehalogenation of aromatic chlorohydrocarbons. In Proceedings of 20th Informal Meeting on Mass Spectrometry. p. 54-55, 2002.

DRBÁLKOVÁ, E., JANDERKA, P., LOEFFLER, T. Studium elektrochemické hydrogenace aromatických chlorderivátů pomocí ON-LINE diferenciální elektrochemické hmotnostní spektrometrie (The study of electrochemical hydrogenation of aromatic chlorohydrocarbons by means of on-line differential electrochemical mass spectrometry). In Sborník abstrakt příspěvků III. pracovního setkání fyzikálních chemiků a elektrochemiků. p. 19-19, 2002.

JANDERKA, P., DRBÁLKOVÁ, E., LOEFFLER, T. Elektrochemická dehalogenace aromatických halogenovaných sloučenin ve vodném prostředí (Electrochemical dehalogenation of aromatic halogenated compounds in aqueous medium). In Sborník přednášek z XXII. celostátního semináře "Moderní elektrochemické metody". p. 64-66, 2002.

JANDERKA, P., TRNKOVÁ, L., SOPOUŠEK, J. Modernizace praktické výuky fyzikální chemie (Modernization of practical education in physical chemistry). In Sborník abstrakt III. pracovního setkání fyzikálních chemiků a elektrochemiků. p. 29-29, 2002.

JANDERKA, P., DRBÁLKOVÁ, E., LOEFFLER, T. Využití membránového vstupu hmotnostního spektrometru ke studiu elektrochemických systémů (Use of membrane input of mass spectrometer for studying of electrochemical systems). In 54. sjezd chemických společností, Brno. p. 529-529, 2002.

JAN, V., SOPOUŠEK, J., FORET, R. Predikce fázového složení zárupevných ocelí a jejich svárů (Phase Composition prediction of the Heat Resistance Steels and their Weldments). In Metal 2002, 11.mezinarodni konference metalurgie a materialu. p. 1-7.

JAN, V., SOPOUŠEK, J. Simulation of Carbide/Nitride Precipitation in 3%Cr1%Mo/P91 Steel Weldment At Temperature Range 700-575oC. In Thermodynamics of Alloys TOFA 2002. p. PO55, 1 pp.

JARKOVSKÝ, J., VACEK, J., KIZEK, R., TRNKOVÁ, L. Stanovení koncentrace metallothioneinu v parazitech ryb rodu ACANTHOCEPHALUS (Determination of metallothionein concentration in fish parasites of ACANTHOCEPHALUS). In Sborník příspěvků VI. pracovního setkání biochemiků a molekulárních biologů. p. 25-25, 2002.

KAPIČKA, L. Vlastnosti a využití softwaru gNMR (Advantage of gNMR program). In IV. seminář POKROKY V ANORGANICKÉ CHEMII. p. 42-42, 2002.

KAPIČKA, L., ALEXOVÁ, V., DASTYCH, D. Analysis and Prediction of the 31P and 19F NMR Spectra of Cyclophosphazenes: Hexafluorocyclotriphosphazene (F2PN)3. In 3rd Workshop of Physical Chemists and Electrochemists. p. 30-30, 2002.

KAPIČKA, L., KUBÁČEK, P. On Geometry and Electron Structure of (F2PN)4. In Chemické Listy, 54.sjezd chemických společností, Brno. p. 355-356, 2002.

KAPIČKA, L., KUBÁČEK, P. The Conformational Behaviour of (F2PN)4. In IV. seminář POKROKY V ANORGANICKÉ CHEMII. p. 41-41, 2002.

MAREK, R., BRUS, J., TOUŠEK, J., KOVÁCS, L., HOCKOVÁ, D. 15N NMR study of N7- and N9-substituted purine derivatives. In 16th European Experimental Nuclear Magnetic Resonance Conference. p. PB129, 1 pp, 2002.

MAREK, R., LUKÁŠKOVÁ, M., TOUŠEK, J., BRUS, J., TRÁVNÍČEK, Z. Protonation and Tautomerism of 6-Benzylaminopurine Derivatives. In 17th NMR Valtice. p. 27-27, 2002.

SEČKÁŘOVÁ, P., HULOVÁ, D., MAN, S., TOUŠEK, J., DOSTÁL, J., DOMMISSE, R., PIETERS, L., MAREK, R. O-Nucleophile Initiated Transformations of Berberine and Coptisine - an NMR Study. In Abstracts ANZMAG2002. p. 116-116.

SEČKÁŘOVÁ, P., HULOVÁ, D., MAREK, J., DOSTÁL, J., SKLENÁŘ, V., DOMMISSE, R., MAREK, R. Berberine and palmatine - the adventures of studying their derivatives. In 9th Blue Danube Symposium on Heterocyclic Chemistry. 1 p, 2002.

STROUHAL, M., KIZEK, R., VACEK, J., TRNKOVÁ, L. Vliv těžkých kovů na koncentraci metallothioneinu u kvasinky YARROWIA LIPOLYTICA (Effect of heavy metals on metallothionein concentration in YARROWIA LIPOLYTICA). In Sborník VI. pracovního setkání biochemiků a molekulárních biologů. p. 26-26, 2002.

SVOBODA, M., SOPOUŠEK, J., VŘEŠŤÁL, J. Structure Changes in Superaustenitis Steel During Long-Term Annealing. In Procedings of the VIII Seminar Diffusion and Themodynamics of Materials. p. 135-138, 2002.

SVOBODA, M., VŘEŠŤÁL, J., SOPOUŠEK, J. Kinetics of Equilibrium State Setting in Superaustenitic Anticorrosion Steels. In Thermodynamics of Alloys TOFA 2002. p. OR40, 1 p.

TOPINKOVÁ, J., TRNKOVÁ, L., HAVEL, J. Use of artificial neural networks for the evaluation UV-Vis spectra of adenine and cytosine in mixtures. In Chemické listy. p. 482-482, 2002.

TOUŠEK, J., MAREK, R., BRUS, J. Ab Initio Calculations and NMR Study of 15N Chemical Shielding Tensors of N7- and N9- Substituted Purine Derivatives. In International Chemometric Conference CHEMOMETRIC VI. p. 124-124, 2002.

TOUŠEK, J., MAREK, R., BRUS, J., KOVÁCS, L., HOCKOVÁ, D. Kvantově chemické výpočty tenzorů chemického stínění N7 a N9 substituovaných purinových derivátů (Quantum Chemical Calculations of the Chemical Shielding Tensors of N7 and N9 Substituted Purine Derivatives). In III. pracovní setkání fyzikálních chemiků a elektrochemiků - Sborník příspěvků. p. 44-44, 2002.

TRNKOVÁ, L. Analytické využití eliminační voltametrie (Analytical use of elimination voltammetry). In 54. sjezd chemických společností, Brno. p. 530-530, 2002.

TRNKOVÁ, L., JELEN, F., POSTBIEGLOVÁ, I. Elimination voltammetry of short oligonucleotides. In Electrochemistry in Molecular and Microscopic Dimensions, 53rd Annual Meeting of the International Society of Electrochemistry, Book of Abstracts. p. 105-105, 2002.

TRNKOVÁ, L., JELEN, F., POSTBIEGLOVÁ, I. Rozlišení signálů adeninu a cytosinu v oligonukleotidech pomocí eliminační voltametrie (The resolution of adenine and cytosine signals in oligonucleotides by means of elimination voltammetry). In Sborník přednášek z XXII.celostátního semináře. p. 29-30, 2002.

TRNKOVÁ, L., KIZEK, R., VACEK, J. Katalytický signál metallothioneinu na rtuťové elektrodě: kombinace chronopotenciometrie a adsorptivní přenosové techniky (Catalytic signal of metallothionein on mercury electrode: combination of chronopotentiometry with adsorptive transfer stripping technique). In Sborník příspěvků III. pracovního setkání fyzikálních chemiků a elektrochemiků v Brně. p. 46-46, 2002.

TRNKOVÁ, L., KIZEK, R., VACEK, J. Modernizace výuky biofyzikální chemie (Modernization of education in biophysical chemistry). In Sborník příspěvků III. pracovního setkání fyzikálních chemiků a elektrochemiků. p. 45-45, 2002.

TRNKOVÁ, L., PEŇA-MENDEZ, E. M., TOPINKOVÁ, J., HAVEL, J. Partial least squares and artificial neural networks for multicomponent analysis from derivative UV-Vis spectra. In International Chemometric Conference CHEMOMETRICS VI. p. P21, 1 p, 2002.

TRNKOVÁ, L. Přednosti eliminační voltametrie (Advantages of Elimination Voltammetry). In Moderní polarografické/voltametrické metody analýzy vod a vodných roztoků, Sborník přednášek z celostátního semináře. p. 96-99, 2002.

TRNKOVÁ, L., SOUKENÍKOVÁ, N., ADAM, V., MAZAL, C. Elektrochemické chování azidových sloučenin na rtuťových elektrodách (Electrochemical behaviour of azide compounds on mercury electrodes). In Sborník přednášek z XXII.celostátního semináře Moderní elektrochemické metody. p. 31-33, 2002.

VACEK, J., ANDRYSÍK, Z., TRNKOVÁ, L., ADAM, V., KIZEK, R. Stanovení azidothymidinu v lidské moči, krevním séru a krvi (Determination of azidothymidine in human urine, serum and whole blood). In Sborník příspěvků VI. pracovního setkání biochemiků a molekulárních biologů. p. 22-22, 2002.

VACEK, J., PETŘEK, J., HAVEL, L., KOUTNÁ, D., ADAM, V., TRNKOVÁ, L., KIZEK, R. Stanovení olova a rostlinných metallothioneinů v explantátových kulturách smrku ztepilého (Picea abies L.) (Determination of plant metallothioneins in explantate culture spruce (Picea abies L.)). In Sborník příspěvků VI. pracovního setkání biochemiků a molekulárních biologů. p. 23-23, 2002.

VŘEŠŤÁL, J., HOUSEROVÁ, J., ŠOB, M. Ab initio calculations of stability of phases and construction of phase diagrams. In Proceedings of VIII.Seminar Diffusion and Thermodynamics of Materials. p. 107-110, 2002.

VŘEŠŤÁL, J., HOUSEROVÁ, J., ŠOB, M. First principles calculations of lattice stabilities of complex structures. In Proceedings of 34.International October Conference on Mining and Metallurgy. p. 564-569, 2002.

VŘEŠŤÁL, J. Studie chemické kinetiky pomocí membránového vstupu k hmotnostnímu spektrometru (Chemical kinetics study using membrane introduction mass spectrometry). Chemické listy, Praha : Česká společnost chemická, 96, 6, p. 532-532, 2002.

VŘEŠŤÁL, J., ŠOB, M. Ab initio výpočty stability fází a konstrukce fázového diagramu (Ab initio calculations of stability of phases and phase diagram construction). Chemické listy, Praha : Česká společnost chemická, 96, 6, p. 437-437, 2002.

Major popularisations and other professional publications: HOLÍK, M.: Reaction of the Interpreter on the Discussion of theacher reading ”reaction mechanisms”, Chem. listy, 96, 850 (2002), ISSN 0009-2770.

HOLÍK, M.: 17th NMR Valtice, Bulletin of the Spectroscopic Society J.M.Marci, 114, 15 (2002)

TRNKOVÁ, L.: Two Workshops in the Faculty of Science, Masaryk University, Brno, MU and Foundation Universitas Masarykiana, No.4, p. 24-29, 2002, Brno, ISSN 1211-6866.


Grant Agency of the Czech Republic 106/02/0876 Brož, P. (co-ordinator Buršík, J., IPM AS CR Brno): Theoretical and experimental study of Ni-based model systems and thermodynamic description of phase equilibria

203/00/0511 Sklenář, V.: Dynamics and Thermodynamics of Mouse Pheromone - Protein Complexes. 106/00/0855 Sopoušek, J. (co-ordinator Foret, R., FSI VUT Brno): Kinetics of Carbide Precipitation in Cr-Mo Steels

203/02/0422 Trnková, L.(co-ordinator Jelen, F., Institute of Biophysics, Brno): New trends in electrochemistry of nucleic acids and their application in enviromental chemistry. 106/00/0174 Vřešťál, J. (co-ordinator Kroupa, A., IPM AS CR Brno):Thermodynamics of equilibrium states and kinetics of phase transformations in the transition metals systems with N and C. 106/02/0877 Vřešťál, J.: Experimental and theoretical studies of stability of intermetalic phases on the base of transition metals Grant Agency of the Academy of Sciences of the Czech Republic A 1163201 (G0396) Trnková, L.: Application of adsorptive transfer and elimination techniques in oligonucleotides and nucleic acids analysis. Grant Agency of the Ministry of Education, Youth and Sports F0808/2002 (G0382) Janderka, P.: Advanced Kinetics Methods F4812/2002 (G0385) Kubáček, P.: EPR-spectroscopy in examples. F 0794/2002 (G0380) Trnková, L.: Multimedial learning texts for seminar on physical chemistry. COST OC. 531.001 (G0336) Vřešťál, J: Theoretical modelling of phase diagrams of alloys with low melting points. KONTAKT TSR-004-99 Vřešťál, J.: Differential Electrochemical Mass Spectrometry (DEMS) of Aromatic Compounds. KONTAKT ME 428 (G0332) Vřešťál, J.: Development of new evaluation methods in chemistry.

CEEPUS SK 102 (G0335) Vřešťál, J. CONFERENCES (SYMPOSIA, SEMINARS) ORGANIZED BY THE DEPARTMENT STAFF MEMBERS

17th NMR Valtice, Meeting of the Central European NMR Discussion Groups. 8.-10.4. 2002, Valtice, CR, Holík M. - Chairman of the Organizing Committee. 54th Congress of Chemical Societies of Czechia and Slovakia, Brno, 1.- 4.7.2002, Holík M. – Member of the Organizing Committee. Chemometrics VI, International Chemometric Conference, Brno, 1.-5.9.2002, Holík M. - Member of the Organizing Committee. 3rd Workshop of Physical Chemists and Electrochemists. 6.2.2002, Brno, CR, Janderka P. - Member of Organizing Committee 3st Workshop of Physical Chemists and Electrochemists. 6.2.2002, Brno, CR, Trnková L. - Chairman of the organizing committee. 6th Workshop of Biochemists and Molecular Biologists. 7.2.2002, Brno, CR, Trnková L. - Member of the organizing committee.

Chemometrics VI., Brno, CR, Trnková L. - Member of the organizing committee.

VIII. Seminar on Diffusion and Thermodynamics of Materials, 4.-6.9.2002, Brno, CR, Vřešťál, J. – Member of the Scientific Committee.

34.IOC on Minning and Metallurgy, 30.9.-3.10.2002, Bor, Yugoslavia, Vřešťál,J. - Member of the Scientific Committee


Brož, P.: Analytical and kinetic studies by means of membrane introduction mass spectrometry, Nankai University Tian-jin, China, 19.-26.11.2002.

Janderka, P.: Dechlorination of Chlorobenzene – a DEMS study, University Bonn, Bonn, Germany, 27.5.-7.6.2002.

Janderka, P.: Electrochemistry on-line combined with Mass Spectrometry, Nankai University Tian-jin, China, 19.-26.11.2002.

Sopoušek J.: The Pennsylvania State University, Department of Material Sci. and Eng. (Prof. Zi-Kui Liu), U. S. A., 19. 5. - 20. 6. 2002, project of Ministry of Education, Youth and Sports.

Trnková, L.: Department of Analytical Chemmistry, University of Barcelona, Spain, 16.-22.12.2002

Vřešťál, J.: Modelling of Thermodynamic Properties of Phases and CALPHAD Method. 25.11.2002, Bor, Yugoslavia

OTHER INTERNATIONAL CONTACTS AND CO-OPERATIONS OF STAFF MEMBERS Foreign visitors

Thomas Loeffler, University Bonn, Bonn, Germany, 2 weeks, study stay, lecture. Cooperations

Collaboration with the Institut of Theoretical and Physical Chemistry, University Bonn, Germany, prof.H.Baltruschat (P.Janderka, J.Vřešťál).

Collaboration with Nankai University Tianjin, China, prof. Lin, Shao-fan (P.Brož, P.Janderka,) .

Collaboration with the Department of Physical Chemistry, Davis, University of California, USA, prof. R.W. Fawcett (L.Trnková).

Collaboration with the Institute of Biophysics AS CR, Brno, Czech Republic (L. Trnková).

Collaboration with the J. Heyrovský Institute of Physical Chemistry, Praha, Czech Republic (L. Trnková).

Collaboration with the Institute of Physics of Materials AS CR Brno, Czech Republic ( J.Vřešťál, P.Brož, J.Sopoušek).


Láňová, B.: University Bonn, Bonn, Germany, 1 year.

Lichnerová, E.: TU München, Germany, 1 year.

Picha, R.: University of Vienna, Vienna, Austria, 6 months


Holík, M.: Member of the Czech Committee for Chemistry-national associate organization to IUPAC, Chairman of the Discussion Group Magnetic Resonance Spectroscopy, Secretary of the Brno Branch of the Czech Chemical Society, Member of the German Chemical Socienty, Member of the Physical Chemistry Board for Ph.D.studies, Palacký University, Olomouc, Member of the Physical Chemistry Board for Ph.D.studies, Faculty of Chemistry, Technical University, Brno, Member of the Physical Chemistry Board for Ph.D.studies, Masaryk University, Brno,. Member of the Organic Chemistry Board for Ph.D.studies, Masaryk University, Brno.

Janderka, P.: Member of the Physical Chemistry Board for Ph.D.studies, Masaryk University, Brno.

Kubáček, P.: Member of the Physical Chemistry Board for Ph.D.studies, Masaryk University, Brno.

Sklenář, V.: Member of the Editorial Board of the Journal of Magnetic Resonance Academic Press San Diego, USA, Member of the New York Academy of Sciences, Member of the Council of the Society International Society of Magnetic Resonance, Member Groupement Ampere, Member of the Physical Chemistry Board for Ph.D.studies, Masaryk University, Brno, Member of the Scientific Council, Faculty of Science, Masaryk University, Brno, Member of the Scientific Council, Masaryk University, Brno, Member of the Scientific Council, Charles University, Prague.

Sopoušek,J.: External supervisor (Vít,J.: Kinetics of Carbide Precipitation in Heat-resistant Steels).

Studničková, M.: Member of the Physical Chemistry Board for Ph.D.studies, Masaryk University, Brno.

Vřešťál, J.: Member of Scientific Board of Institute of Physics of Materials Academy of Sciences of the Czech Republic, Brno, Member of Scientific Board Faculty of Science Palacký University Olomouc and Chemical Faculty of Technical University, Brno, Member of the Physical Chemistry Board for Ph.D.studies, Masaryk University, Brno, Member of the Physical Chemistry Board for Ph.D.studies, Palacký University, Olomouc, Member of the Physical Chemistry Board for Ph.D.studies, Technical University, Brno.

AWARDS GIVEN TO STAFF MEMBERS AND STUDENTS

Holík, M.: Hanuš- Medal Czech Chemical Society

Vřešťál, J.: Medal-10. Years Chemical Faculty Technical University Brno

Houserová, J.: Prize of Dean of Faculty of Science

Pícha, R.: Prize of Dean of Faculty of Science

RECETOX Research Center for Environmental Chemistry and Ecotoxicology


RECETOX (Research Centre for Environmental Chemistry and EcoTOXicology) was established in July 7, 1994. The Centre was a research unit of the Department of Environmental Chemistry and Ecotoxicology. In 2001, RECETOX merged with the Department of Environmental Chemistry and Ecotoxicology and, since, provides master and postgraduate studies in the fields of environmental protection, ecotoxicology and environmental chemistry. In 2002, RECETOX was honoured by European Commission and currently is supported by European Union as "The Center of Excellence for Environmental Chemistry and Ecotoxicology". At present, RECETOX is an interdisciplinary, inter-institutional research and teaching centre working in the field of fundamental research in the environmental chemistry, ecotoxicology and risk analysis, as well as with the training of bachelor, master and postgraduate students in the fields of environmental chemistry and ecotoxicology.

Centre is not setting a goal to be a large research workplace or institute but it is based on the philosophy of relatively smaller groups of co-workers and ad hoc research teams. The fundamental goal of RECETOX is to participate in joint research projects with European institutes and to establish creative scientific teams from various countries for the solution of environmental problems, grants, and orders from industry etc. External co-workers of the Centre take significant part on education in both master and doctoral studies.

Structure of RECETOX is as follows: Division of Environmental Chemistry (Head: Ivan Holoubek), Ecotoxicology Division (Head: Luděk Bláha), Environmental Analytical Chemistry Division (Head: Jana Klánová), Risk Analysis and Data Evaluation (Head: Ladislav Dušek). RECETOX staff consists of members of the Faculty of Science and outside co-workers from the Czech Republic and other countries. Research activities of RECETOX are based on the basic philosophy of Project TOCOEN (TOxic COmpounds in the ENvironment) and are focused on the following research topics: environmental fate and long-range transport of persistent organic pollutants, research and development of new ecotoxicological tests and methods, methodology of environmental and ecological risk assessment, mathematical modelling of the fate of pollutants, regionally-specific ecological risk assessment activities based on available multivariate environmental data, development of effective biomonitoring of stressed soils in Czech Republic, development of a novel type of software for environmental science based on expert-system built over interactive database.

The original objective of TOCOEN Project was extended to cover heavy metals, natural toxins and Persistent, Bioaccumulative and Toxic pollutants (PBTs). The acronym TOCOEN is now interpreted as "TOxic COmpounds in the ENvironment" and running projects are concerned with persistent toxic substances (PTS). Currently, the main goal are the studies of relations between the concentration levels of pollutants in the environment and their potential effects to living organisms. Additionally, risk assessment and the fate of selected organic pollutants in the environment is studied in details. This includes inputs of PTS to various parts of environment (through emissions), their transport in compartments and between them, their transformations (photochemical, chemical, thermal, biochemical), their biological effects (dose / concentration - exposure analysis), modelling of the processes, and risk assessment, management and prognosis of contamination development.

Certain groups of PTS such as polycyclic aromatic hydrocarbons (PAHs), chlorinated pesticides (OCPs), polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) were selected as model compounds at the beginning of the project. Currently, other groups of organics such as chlorinated benzenes, phenols, certain other types of pesticides, chlorinated aliphatic hydrocarbons and other chlorinated aromatic compounds are also being intensively studied. Model compounds are studied in all environmental compartments. New research topics are also focused on the environmental photochemistry of PBT compounds in ice and environmental surfaces (in co-operation with research group of dr. Petr Klan, Dept. of Organic Chemistry, Faculty of Science, Masaryk University), assessment of toxicity and ecotoxicity of environmental photoreaction products, studies of effects of new types of PBTs, such as chlorinated paraffins or brominated compounds.

From 1997, cooperating research groups of the RECETOX team, TOCOEN, Ltd., and several other Czech and international institutions use for their common presentations the acronym RECETOX - TOCOEN & Associates (R - T & A). Present activities of R - T & A group are focused on the establishment a Scientific Network on Persistent, Bioaccumulative and Toxic Chemicals (PBTs). The main goal of this Network is to bring together scientists working in this field and to explore the potential of an organised and coordinated research programme

on persistent, bioaccumulative and toxic chemicals at a European level. This scientific network aims to provide a platform for scientists working in the field of environmental chemistry, environmental toxicology, ecotoxicology and risk analysis.

The basic scientific topic of the newly established Center of Excellence "RECETOX" is the study of relationships between environmental occurrence and levels of various types of pollutants (mainly persistent, bioaccumulative and toxic - PBTs). The activities of the Centre of Excellence cover: (1) establishement of the European scientific network on persistent, bioaccumulative and toxic substances based on the previous activities in this field; (2) the Central and Eastern European Countries PBTs Network with special attention to the PBT environmental contamination in the region; (3) Czech National Network in Environmental Chemistry and Ecotoxicology. These networks organize under the auspice of the Centre every year special workshops and thematic conferences as a base for exchange of scientific results and information and common preparation of various projects and programmes. Educational activities are focused on the exchange of scientists, PhD students and postdoctoral students and also on the preparation of specifically oriented Summer school. As a part of common networks activities, the special study concerning to PBTs in Central and Eastern European Countries and special environmental database will be developed.

RECETOX have participated on the Global Inventory of Persistent Toxic Substances as a part of activities which are connected with implementation of Stockholm Convention. RECETOX coordinated this inventory for European region and was responsible for preparation of European Regional Report, which was prepeared as a part of project "Regionally Based Assessment of Persistent Toxic Substances Covered by UNEP Chemicals and GEF.

DEPARTMENT STAFF

Head: Ivan Holoubek (Prof., RNDr., CSc.) Professor: Jiří Matoušek (Prof., Ing., DrSc.) - part time Associate Professors: Aleš Hrdlička (Doc., RNDr., CSc.) - till August 2002 Blahoslav Maršálek (Doc., Ing., CSc.) - part time Zdeněk Šimek (Doc., RNDr., CSc.) - part time Assistant Professors: Ladislav Dušek (RNDr.,Dr.) Luděk Bláha (Mgr., Ph.D.) Pavel Čupr (Mgr., Ph.D.) - part time Research Assistants: Jakub Hofman (Mgr.) Alena Ansorgová (RNDr.) - till August 2002 Jana Klánová (RNDr.) - part time Irena Holoubková (RNDr.) - part time Jiří Kohoutek (Mgr., Ing.) - part time Technicians: Romana Kostrhounová (Ing.) Eva Krejčí - from July 2002 Iva Poláková (Mgr.) - on maternity leave Secretary: Hana Kordačová Adjunct Lecturers: Petr Anděl (RNDr., CSc.) - Evernia Ltd., Liberec Jiřina Hofmanová (Doc., RNDr., CSc.) - Institute of Biophysics, Academy of Sciences CR, Brno Anton Kočan (Ing., CSc.) - Institute of Preventive and Clinical Medicine, Bratislava, Slovakia Alois Kozubík (Doc., RNDr., CSc.) - Institute of Biophysics, Academy of Sciences CR, Brno Miroslav Machala (RNDr., CSc.) - Veterinary Research Institute, Brno Ph.D. Students: Full time Michal Boháč (Mgr.) Pavel Babica (Mgr.) Jindřiška Dolinová (Mgr.) Michaela Drábková (Mgr.)

Veronika Dupalová (Mgr.) Alan Gavel (Mgr.) Jakub Gregor (Mgr.) Jakub Hofman (Mgr.) Jaroslav Janošek (Mgr.) Andrea Jesenská (Mgr.) Daniel Klimeš (Mgr.) Eva Kmentová (Mgr.) Petra Kosubová (Mgr.) Ivana Marková (Mgr.) Kateřina Minksová-Chramostová (Mgr.) Petr Pavliš (Mgr.) Martina Pavlová (Mgr.) Martina Plíšková (Mgr.) Petra Růžičková (Mgr.) Lenka Šindlerová (Mgr.) Michal Škarek (Mgr.) Roman Šmíd (Mgr.) Petra Štejnarová (Mgr.) Part time Alena Ansorgová (RNDr.), Masaryk University, Brno Miroslav Ciganek (RNDr.), Veterinary Research Institute, Brno Jana Klánová (RNDr.), TOCOEN, s.r.o Stanislav Malý (Mgr.), ÚKZUZ, Brno Soňa Marvanová (Mgr.), CDV, Brno Vladimír Podborský (RNDr.) Military Research Institute, Brno Marie Skybová (RNDr.), EKOTOXA Ltd., Opava Pavla Sýkorová (RNDr.), Palacky University, Oloumouc Helena Zahradníčková (RNDr.), Institute of entomology, Academy of Sciences CR, České Budějovice Vendula Zlevorová (Mgr.), Faculty of Chemistry, Technical University, Brno


Diploma theses: Babica, P.: Contribution to exposure, effects and risk analysis of cyanotoxins (supervisor: L. Bláha) (in Czech)

Bezchlebová, J.: Validation of qCO2 coefficient (supervisor: J. Hofman) (in Czech)

Breineková, K.: Mechanisms of oxidative stress and ecotoxicological applications (supervisor: L. Bláha) (in Czech)

Drábková, M.: Selection of cyanocide compounds for elimination of cyanobacteria (supervisor: B. Maršálek) (in Czech)

Dupalová, V.: HPLC determination of chlorophenols using fluorescent detection (supervisor: A. Hrdlička) (in Czech)

Janošek, J.: In vitro testing of PBT pollutants (supervisor: M. Machala) (in Czech)

Kapplová, P.: Biomarkers of tumor promotion - mechanisms of in vitro analyses (supervisor: M. Machala) (in Czech)

Krása, A.: Statistical evaluation of phytoplankton biodiversity (supervisor: L. Dušek) (in Czech)

Martinek, J.: Fluorescence imaging methods in evaluation of algal toxicity tests (supervisor: B. Maršálek) (in Czech)

Mlčáková, J.: HPLC determination of atrazin and its degradation products using fluorescent detection (supervisor: A. Hrdlička) (in Czech)

Nosek, J.: UV-photodegradation of chlorinated phenols in water ice (supervisor: I. Holoubek) (in Czech)

Šindlerová, L.: Applications of cytokinetics in ecotoxicology. (supervisor: A. Kozubík) (in Czech)

Štejnarová, P.: PBT compounds in wet atmospheric deposition (supervisor: A. Ansorgová) (in Czech)

Šváchová, L.: PBT compounds in wet atmospheric deposition (supervisor: A. Ansorgová) (in Czech)

Ph.D. theses: Jesenská, A.: Detoxication of halogenated aliphatic compounds by Mycobacteria

Malý S.: Analysis biotic and abiotic factors affecting microbial indicators

Master of Science Theses Dušek, L.: Ecological Risk Assessment Studies Based on Biomonitoring Data - Biostatistical Modelling Approach

Hodovský J.: Assessment of Quality of Surface Waters - Application of Data from Biomonitoring Studies

Prokop Z.: Bioavailability of Soil and Sediment Contaminants


Books, book chapters and review articles

HOLOUBEK, I., ADAMEC, V., BARTOŠ, M., ČERNÁ, M., ČUPR, P., BLÁHA, K., BLÁHA, L., DEMNEROVÁ, K., DRÁPAL, J., HAJŠLOVÁ, J., HOLOUBKOVÁ, I., JECH, L., KLÁNOVÁ, J., KOHOUTEK, J., KUŽÍLEK, V., MACHÁLEK, P., MATĚJŮ, V., MATOUŠEK, J., MATOUŠEK, M., MEJSTŘÍK, V., NOVÁK, J., OCELKA, T., PEKÁREK, V., PETIRA, O., PUNČOCHÁŘ, M., RIEDER, M., RUPRICH, J., SÁŇKA, M., VÁCHA, R., ZBÍRAL, J. Úvodní národní inventura persistentních organických polutantů v České republice.(An initial inventory of persistent organic polutants in Czech Republic) Project GF/CEH/01/003: ENABLING ACTIVITIES TO FACILITATE EARLY ACTION ON THE IMPLEMENTATION OF THE STOCKHOLM CONVENTION ON PERSISTENT ORGANIC POLLUTANTS (POPs) IN THE CZECH REPUBLIC. 745 pp, 2002.

HOLOUBEK, I., ALCOCK, R., BRORSTROM-LUNDÉN, E., KOČAN, A., PETROSJAN, V., ROOTS, O., SHATALOV, V., AMIROVA, Z., MERGMAN, A., BEYER, A., BLÁHA, L., BUREAUL, P., COLEMAN, P., ČUPR, P., DUTCHAK, S., DUYZER, J., FALANDYSZ, J., FUELL, C., HEINISCH, E., HOLOUBKOVÁ, I., JONES, K., KETTRUP, A., KOHOUTEK, J., KOROLYEVA, S., KRZYZANOWSKI, M., KUBIAK, R., LAMMEL, G., LECLOUX, A., MACHALA, M., MALANICHEV, A., MCLACHLAN, M., LULEK, J., PALM, A., SWEETMAN, A., VAN DE MEENT, D., VAN DER BERG, M., VANDERBROGHT, J., VIJGEN, J., WEISS, P., WENZEL, S. Regionally Based Assessment of Persistent Toxic Substance - European Regional Report. UNEP Chemicals, 147 pp, 2002.

ŠATALOV, V., MALENICHEV, A., VULYKH, N., BERG, T., MANO, S., HOLOUBEK, I., MILUKAITÉ, A.-R., AFINOGENOVA, O., MANTSEVA, E. Assessment of POP transport and accumulation in the environment. EMEP Report 7/2002. 145 pp.

DUŠEK, L., PAVLIŠ, P., SVOBODNÍK, A. Registrace onkologických onemocnění v ČR - existuje prostor pro vývoj ? (Oncological diseases registration in Czech republic - is there any area for further development?). In J. Abrahámová (Ed) Vybrané otázky onkologie VI. p. 10-12, 2002.

DUŠEK, L., VYZULA, R., KLIMEŠ, D., ŠIROKÝ, P., NOVÁK, J., ANDRES, P., DEMLOVÁ, R., ŽALOUDÍK, J. Registrace klinických dat pro hodnocení kvality péče v onkologii - případová studie diagnózy C50 (Clinical data registration for oncological care quality assesment - C50 diagnosis case study). In J. Abrahámová (Ed) Vybrané otázky onkologie VI. p. 94-96, 2002.

SVOBODNÍK, A., ABRAHÁMOVÁ, J., DUŠEK, L., MUŽÍK, J. Epidemiologie ZN mužských pohlavních orgánů ČR - statistická analýza NOR (Epidemiology ZN of men's genitals in Czech Republic - NOR statistical analysis). In J. Abrahámová (Ed) Vybrané otázky onkologie VI. p. 12-15, 2002.

SVOBODNÍK, A., DUŠEK, L., MUŽÍK, J., PECEN, L., NOVOTNÝ, J. Projekt CARMEN - výsledky epidemiologické studie karcinomu prsu u žen v ČR (CARMEN project - results of the epidemiological study of breast cancer in women from Czech Republic). In J. Abrahámová (Ed) Vybrané otázky onkologie VI. p. 97-100, 2002

Scientific papers BEDNAŘÍK, J., VONDRÁČEK, P., LUKÁŠ, Z., DUŠEK, L., CUNDRLE, I. Critical Illness Polyneuromyopathy: Is It a Part of the Multiple organ Failure (a Neuromuscular Failure)?. Neurology, Philadelphia : LIPPINCOTT WILLIAMS & WILKINS, 7, 58, p. A159, 1 pp, 2002.

BLÁHA, L., KAPPLOVÁ, P., VONDRÁČEK, J., UPHAM, B., MACHALA, M. Inhibition of gap-junctional intercellular communication by environmentally occuring polycyclic aromatic hydrocarbons. Toxicological Sciences, Oxford, England : Oxford Univ. Press, 65, 1, p. 43-51, 2002.

CEPÁK, V., ZOBAČOVÁ, M., ZACHLEDER, V. The effect of cadmium ions on the cell cycle of the green flagellate Chlamydomonas noctigama. Algological Studies, Stuttgart : E.Schweizerbart'sche Verlagsbuchhandlung, 106, 1, p. 46-52, 2002.

DVOŘÁKOVÁ, D., DVOŘÁKOVÁ, K., BLÁHA, L., MARŠÁLEK, B., KNOTKOVÁ, Z. Effects of cyanobacterial biomass and purified microcystins on malformations in Xenopus laevis: teratogenesis assay (FETAX). Environmental Toxicology, USA, 6, 17, p. 547-554, 2002.

HÁJEK, R., KOŘÍSTEK, Z., VINKLÁRKOVÁ, J., JANOVSKÁ, E., KLABUSAY, M., DOUBEK, M., DVOŘÁKOVÁ, D., BOURKOVÁ, L., DUŠEK, L., BUCHLER, T., ADLER, J., ADAM, Z., PENKA, M., MAYER, J. Interleukin-2 activation of haematopoietic stem cells. Acta Medica Austriaca, Berlin : BLACKWELL VERLAG GMBH, 29, 2, p. 61-67, 2002.

HILSCHEROVÁ, K., KANAAN, K., HOLOUBEK, I., GIESY, J. Characterization of estrogenic activity of riverine sediments from the Czech Republic. Archives of Environmental Contamination and Toxicology , New York : SPRINGER-VERLAG, 43, 2, p. 175-185, 2002.

KADAŇKA, Z., MAREŠ, M., BEDNAŘÍK, J., SMRČKA, V., KRBEC, M., STEJSKAL, L., CHALOUPKA, R., SURELOVÁ, D., NOVOTNÝ, O., URBÁNEK, I., DUŠEK, L. Approaches to spondylotic cervical myelopathy - Conservative versus surgical results in a 3-year follow-up study. Spine, Philadelphia : LIPPINCOTT WILLIAMS & WILKINS, 27, 20, p. 2205-2210, 2002.

KLÁN, P., HOLOUBEK, I. Ice (Photo)chemistry. Ice as a Medium for Long-Term (Photo)chemical Transformations - Environmental Implications. Chemosphere, Oxford, UK : Elsevier Science Ltd., 46, 8, p. 1201-1210, 2002.

LAUREOVÁ, L., DUŠEK, L., ŠIMÍČKOVÁ, M., KOCÁK, I., VAGUNDOVÁ, M., ŽALOUDÍK, J., KOVAŘÍK, J. Malignant melanoma associates with Th1/Th2 imbalance that coincides with disease progression and immunotherapy response. Neoplasma, Bratislava : SLOVAK ACADEMY SCIENCES, 3, 49, p. 159-165, 2002.

MACHALA, M., BLÁHA, L., VONDRÁČEK, J., LEHMLER, H.-J.,ROBERTSON, L.W., MALMBERG, T. Comparison of relative toxic potencies of hydroxylated PCBs and quinones in hepatic and mammary cell lines. Organohalogen Compounds, USA, 56, 1, p. 25-28, 2002.

MATOUŠEK, J. Assistance and Protection - One of the main pillars of the Chemical Weapons Convention: Czech Republic access to the Article X of the Convention. Perspectives: The Central European Review of International Affairs, Praha : Institute of International Relations, 18, 1, p. 53-65, 2002.

MATOUŠEK, J. Ochrana obyvatelstva v proměnách času III. Zkušenosti z druhé světové války (Protection of population through ages III. Experience gained during World War II.). Rescue Report, ČR, 5, 3, p. 11-11, 2002.

MATOUŠEK, J. Ochrana obyvatelstva v proměnách času II. Zrod civilní obrany v meziválečném období jako reakce na očekávané hrozby (Protection of population through ages II. Civil defence birth between wars as reaction to expected threats). Rescue Report, ČR, 5, 2, p. 11-11, 2002.

MATOUŠEK, J. Ochrana obyvatelstva v proměnách času I. Přírodní a válečné hrozby v historii - preludium civilní obrany (Protection of population through ages I. Threats of nature and war in history - Overture to civil defence). Rescue Report, ČR, 5, 1, p. 11-11, 2002.

MATOUŠEK, J. Ochrana obyvatelstva v proměnách času IV. Civilní obrana ve stínu jaderných zbraní (Protection of population through ages IV: Civil defence in context of nuclear weapons). Rescue Report, ČR, 5, 4, p. 13-13, 2002.

MATOUŠEK, J. Ochrana obyvatelstva v proměnách času VI. Reakce civilní obrany na vývoj zbraní hromadného ničení (Protection of population through ages VI: Civil defence reaction on NBC-weapons development). Rescue Report, ČR, 5, 6, p. 10-10, 2002.

MATOUŠEK, J. Ochrana obyvatelstva v proměnách času V. Začátek Studené války a civilní obrana (Protection of population through ages V: Cold war and civil defence). Rescue Report, ČR, 5, 5, p. 12-12, 2002.

MATOUŠEK, J. Ochrana proti válečným a mírovým škodlivinám III. Civilní ochranné masky pro dospělou populaci (Protection from harmful substances III. Civilian protective masks for adult population). Rescue Report, ČR, 5, 3, p. 12-12, 2002.

MATOUŠEK, J. Ochrana proti válečným a mírovým škodlivinám II. Prostředky osobní ochrany : Ochranné masky vojskového typu. (Protection from harmful substances II. Personal protection means: Army-type protective masks of). Rescue Report, ČR, 5, 2, p. 12-12, 2002.

MATOUŠEK, J. Ochrana proti válečným a mírovým škodlivinám IV. Ochranné masky a prostředky pro dětskou populaci (Protection from harmful substances IV. Protective masks for children population). Rescue Report, ČR, 5, 4, p. 14-14, 2002.

MATOUŠEK, J. Ochrana proti válečným a mírovým škodlivinám I. Význam a současné postavení systému metod a prostředků ochrany ve válkách, ozbrojených konfliktech a mírové době (Protection from harmful substances I. Importance of protective methods during war and peace). Rescue Report, ČR, 5, 1, p. 12-12, 2002.

MATOUŠEK, J. .: Ochrana proti válečným a mírovým škodlivinám VI. Ochranné oděvy pro jedno použití a improvizované prostředky (Protection from harmful substances VI. Disposable protective clothes and extemporary means). Rescue Report, 5, 6, p. 11-11, 2002.

MATOUŠEK, J. Ochrana proti válečným a mírovým škodlivinám V. Ochranné oděvy - klasické izolační oděvy (Protection from harmful substances V. Protective clothes - classical isolation clothes). Rescue Report, ČR, 5, 5, p. 13-13, 2002.

MATOUŠEK, J., STŘEDA, L. Mezinárodně-právní aspekty boje proti globálnímu terorismu (International-law aspects of struggle for global terorism). Mezinárodní politika, Praha : Ústav mezinárodních vztahů, 26, 8, p. 13-15, 2002.

MATUŠKA, P., PILAROVÁ, O., MERTA, Z., SKŘIČKOVÁ, J., DUŠEK, L. The influence of co-morbidity on the outcome of non-invasive ventialtory supprot in patients with acute respiratory failure (ARF) in chronic abstructive pulmonary disease (COPD). Eur. Resp. J, EU : EU, 20, 38, p. 277-278, 2002.

NOVOTNÝ, J., PECEN, L., PETRUŽELKA, L., BÁRTA, M., ČERVENKOVÁ, J., SVOBODNÍK, A., DUŠEL, L. Mathematical model predicting individual breast cancer risk. The result of case-control study of 7,000 women. INTERNATIONAL JOURNAL OF CANCER, New York : WILEY-LISS, 13, 1, p. 173-345, 2002.

SMILEK, P., KOSTŘICA, R., ROTTENBERG, J., HLOŽEK, J., DUŠEK, L., VESELÝ, K. Prognostické faktory karcinomu faryngu a supraglottis (Prognostic factors in the pharyngeal and supraglottis carcinoma). Choroby hlavy a krku ( Head and Neck Diseases), Slovenská republika : Slovenská spoločnost pre otolaryngológiu, 5, 1, p. 23-29, 2002.

STŘEDA, L., MATOUŠEK, J. Ultraterorismus - jaderný, radiologický, chemický a biologický terorismus (Ultraterorism - nuclear, radiological, chemical and biological terorism). Vojenské rozhledy : teoretický časopis armády České republiky, Praha : Ministerstvo obrany ČR - AVIS, 43, 1, p. 98-113, 2002.

Abstracts of conference papers and posters BEZCHLEBOVÁ, J., HOFMAN, J. Using microbial summary parameters as biological indicators of soil quality in long term cultivation of real soils. In Book of Abstracts - SECOTOX 2002, Trends and Advances in Environmental Chemistry and Ecotoxicology, Brno, 14-16/10/2002. p. 147-149.

BLÁHA, L., BABICA, P., SABATER, S., ADMIRAAL, W., MARŠÁLEK, B. Screening of the health risks of biofilms using a battery of in vitro toxicity assays. In Book of Abstracts - SECOTOX 2002, Trends and Advances in Environmental Chemistry and Ecotoxicology, Brno, 14-16/10/2002. p. 150-154.

BLÁHA, L., KAPPLOVÁ, P., LEHMLER, H.-J., ROBERTSON, L.W., MACHALA, M. Relative potencies of oxygenated polychlorinated biphenyls to inhibit gap-junctional intercellular communication in WB-F344 cells. In Book of Abstracts - The 2nd PCB Workshop: Recent Advances in the Environmental Toxicology and Health Effects of PCBs Emphasis on the latest advances and the perspective of Central and Eastern Europe. Brno, CR, 07-11/05/2002. p. 125-125.

BLÁHA, L., MACHALA, M., VONDRÁČEK, J. In vitro biotesty pro detekci negenotoxických procesů - studie efektů PAHs a hydroxyderivátů PCBs (In vitro biotests for detection of nongenotoxic processes - studies of effects of PAHs and hydroxyderivatives of PCBs). In Sborník pracovní konference - Ekotoxikologické Biotesty I, Seč u Chrudimi, 18-19/9/2002. p. 129-136.

BLÁHA, L., SOVADINOVÁ, I., VONDRÁČEK, J., LEHMLER, H.-J., ROBERTSON, L.W., MACHALA, M. Comparison of AhR and ER mediated activities of hydroxyderivatives of polychlorinated biphenyls detected in vitro with luciferase reporter gene techniques. In Book of Abstracts - The 2nd PCB Workshop: Recent Advances in the Environmental Toxicology and Health Effects of PCBs Emphasis on the latest advances and the perspective of Central and Eastern Europe. Brno, CR, 07-11/05/2002. p. 126-126.

BLÁHA, L., VONDRÁČEK, J., LEHMLER, H.-J., ROBERTSON, L.W., MALMBERG, T., MACHALA, M. Acute inhibition of gap junctional intercellular communication by polychlorinated biphenyls and their metabolites - relative inhibitory potencies, structure-activity relationship and intracellular singnalling. In Book of Abstracts - International Summer School, NATO/FEBS Advanced Study Institute - Spetses, Greece, 18-30/8/2002. p. 9-9.

BLÁHA, L., VONDRÁČEK, J., UPHAM, B.L., MACHALA, M. Inhibition of GJIC by polychlorinated biphenyls: inhibitory potencies and screening for potential mode(s) of action. In SECOTOX 2002, Trends and Advances in Environmental Chemistry and Ecotoxicology, Book of Abstracts. p. 155-158.

ČUPR, P., ŠKAREK, M., FLEGROVÁ, Z., VAN DYK, T. Využití luminiscenčních in vitro testů pro detekci genotoxického potenciálu (Applications of in vitro luminiscence tests for detection of genotoxic potential). In Sborník pracovní konference - Ekotoxikologické Biotesty I, Seč u Chrudimi, 18-19/9/2002. p. 115-128.

DOLINOVÁ, J., KLÁN, P., HOLOUBEK, I. Photolysis of Aromatic Compounds in Water Ice Containing Hydrogen Peroxide. In SECOTOX, 7th Regional Meeting of the Central and Eastern European Section. p. 43-43, 2002.

DOLINOVÁ, J., KLÁN, P., HOLOUBEK, I. Photolysis of benzene and phenol in water ice containing hydrogen peroxide. In XIXth IUPAC Symposium on Photochemistry. p. 185-185, 2002.

DOLINOVÁ, J., KLÁN, P., HOLOUBEK, I. Photolysis of polycyclic aromatic compounds in water ice containing hydrogen peroxide. In SECOTOX East 2002, 7th Regional Meeting of the Central and Eastern European Section, Trends and Advances In Environmental Chemistry and Ecotoxicology, Book of Abstracts. p. 43-43.

DOLINOVÁ, J., KLÁN, P., KLÁNOVÁ, J., HOLOUBEK, I. Photolysis of benzene and phenol in water ice containing hydrogen peroxide. In XIXth IUPAC Symposium on Photochemistry. p. 185-185, 2002.

DUŠEK, L., JARKOVSKÝ, J., ANDĚL, P., HODOVSKÝ, J., ŠMÍD, R., ZAHRÁDKOVÁ, S., GELNAR, M. Biodiversity measures as environmental indicators - is there a space for generalization over various biological communities under different type of stress ?. In SECOTOX 2002. Trends and Advances in Environmental Chemistry and Ecotoxicology. In Book of contributions. p. 122-126.

DUŠEK, L., PAVLIŠ, P., BLÁHA, L., MARŠÁLEK, B., HOFMAN, J., KLIMEŠ, D., ANDĚL, P., ČUPR, P., KOHOUTEK, J., HOLOUBKOVÁ, I., BLÁHA, K., HOLOUBEK, I. Ekotoxikologické Biotesty v expertním systému komplexního hodnocení ekologických rizik - Projekt IDRIS II (Ecotoxicological Biotests in Expert System of Complex Ecological Risk Assesment - Project IDRIS II). In Sborník pracovní konference - Ekotoxikologické Biotesty I, Seč u Chrudimi, 18-19/9/2002. p. 25-34.

DUŠEK, L., PAVLIŠ, P., ŽALOUDÍK, J., MUŽÍK, J., KOPTÍKOVÁ, J., SVOBODNÍK, A. Software SVOD ve verzi 2.00 (Software SVOD - version 2.00). In Sborník - XXVI. Brněnské onkologické dny, Brno 29.5. - 31.5. 2002. p. 66-70.

DUŠEK, L., ŠTĚRBA, J., REGNER, B., MIHÁL, V., MALIŠ, J., ŠMELHAUS, V., HAJDÚCH, M., ECKSCHLAGER, T., BLAŽEK, B., KOPTÍKOVÁ, J., KEPÁK, T., STARÝ, J., KOUTECKÝ, J. Epidemiologikcá a klinická registrace odpovídající potřebám současné onkologie - modelová studie nádorů dětského věku (Epidemiological and clinical registration accordant to contemporary oncology requirements - model study of children's age tumors). In XXVI. Brněnské onkologické dny, sborník abstraktů. p. 82-87, 2002.

DUŠEK, L., ŠTĚRBA, J., REGNER, B., MIHÁL, V., MALIŠ, J., ŠMELHAUS, V., HAJDÚCH, M., ECKSCHLAGER, T., BLAŽEK, B., KOPTÍKOVÁ, J., KEPÁK, T., STARÝ, T., KOUTECKÝ, J. Epidemiologická a klinická registrace odpovídající potřebám současné onkologie - modelová studie nádorů dětského věku (Epidemiological and clinical registration due to needs of current oncology - model studies of childhood tumors). In Sborník - XXVI. Brněnské onkologické dny, Brno 29.5. - 31.5. 2002. p. 82-87.

FOREJTNÍKOVÁ, H., LUNEROVÁ, H., KUBÍNOVÁ, R., BLÁHA, L., MACHALA, M. Vliv nově syntetizovaných chalkonů na epigenetické faktory karcinogeneze (Effects of newly synthesised chalkons on epigenetic parameters of carcinogenesis). Chemické listy, Praha : Česká chemická společnost, 96, 6, p. 401-401, 2002.

GAVEL, A., MARŠÁLEK, B., MARTÍNEK, J., SOCHOVÁ, I. A novel algal assay for toxicity detection in turbid and coloured environmental samples and waste waters. In SECOTOX 2002, Trends and Advances in Environmental Chemistry and Ecotoxicology, Book of Abstracts. p. 164-164.

GELNAR, M., DUŠEK, L., KOUBKOVÁ, B., ŠEBELOVÁ, Š., MAZOURKOVÁ, M., MATĚJUSOVÁ, I., JARKOVSKÝ, J., MACHALA, M., JURAJDA, P., ZAHRÁDKOVÁ, S. Parasites As Pollution Indicators: Evaluation of Indicative Potential of FISH Parasites Using Hierarchically Structured Data. In Proceedings of the

10th International Congress of Parasitology - ICOPA X: Symposia, Workshops and Contributed Papers. p. 255-264, 10 pp, 2002.

HEINISCH, E., HOLOUBEK, I. PCBs in aquatic ecosystems of the river Elbe and Berlin waters. In Book of Abstracts - The 2nd PCB Workshop: Recent Advances in the Environmental Toxicology and Health Effects of PCBs Emphasis on the latest advances and the perspective of Central and Eastern Europe. Brno, CR, 07-11/05/2002. p. 9-9.

HOFMAN, J., DUŠEK, L., ANSORGOVÁ, A., ANDĚL, P., MALÝ, S., BEZCHLEBOVÁ, J., HOLOUBEK, I. Vícerozměrné hodnocení biologické kvality půd: validace bioindikačních a diskriminačních schopností (Multivariate evaluation of soil biological quality: validation of bioindication and discrimination parameters). In Sborník pracovní konference - Ekotoxikologické Biotesty I, Seč u Chrudimi, 18-19/9/2002. p. 69-85.

HOLOUBEK, I. POPs Enabling activities to facilitate early action in the implementation of the Stockholm Convention on Persistent Organic Pollutants in the Czech Republic. In SECOTOX East 2002, 7th Regional Meeting of the Central and Eastern European Section, Trends and Advances In Environmental Chemistry and Ecotoxicology, Book of Abstracts. p. 234-239.

HOLUBEK, I., KOČAN, A., ALCOCK, R., SWEETMAN, A., JONES, K.C., ROOTS, O., HEINISCH, E., DUTCHAK, S., SHATALOV, V., BREIVIK, K. European sources, regional distribution and environmental levels of PCBs. In Book of Abstracts - The 2nd PCB Workshop: Recent Advances in the Environmental Toxicology and Health Effects of PCBs Emphasis on the latest advances and the perspective of Central and Eastern Europe. Brno, CR, 07-11/05/2002. p. 6-6.

HOLOUBEK, I., MATOUŠEK, J. Persistent organic pollutants in the global environment: Stockholm Convention (2002) and problems of its implementation. (54. Sjezd Chemických Společností) Chemické listy , Praha: Česká chemická společnost, 96, 1, p. 500-501.

JARKOVSKÝ, J., DUŠEK, L., HODOVSKÝ, J., PAVLIŠ, P., ZAHRÁDKOVÁ, S., ŠMÍD, R., KUKLETA, P. Biodiversity and other ecologically weighted indices in bioindication of surface ware quality. In SECOTOX 2002. Trends and Advances in Environmental Chemistry and Ecotoxicology. Book of contributions. p. 126-131.

KLÁNOVÁ, J., KLÁN, P., HOLOUBEK, I. Photolysis and Radiolysis of Chlorophenols in Water Ice. In SECOTOX, 7th Regional Meeting of the Central and Eastern European Section. p. 48-48, 2002.

KLÁNOVÁ, J., KLÁN, P., NOSEK, J., HOLOUBEK, I. Fotochemie chlorfenolů v ledu (Photochemistry of chlorophenols in water ice). (54. Sjezd Chemických Společností) Chemické listy, Praha : Česká chemická společnost, 96, 6, p. 513-514, 2002.

KLÁNOVÁ, J., KLÁN, P., NOSEK, J., HOLOUBEK, I. Photochemistry of chlorophenols in water ice. In XIXth IUPAC Symposium on Photochemistry. p. 288-288, 2002.

KLÁNOVÁ, J., KLÁN, P., NOSEK, J., HOLOUBEK, I. Photochemistry of chlorophenols in water. In SECOTOX East 2002, 7th Regional Meeting of the Central and Eastern European Section, Trends and Advances In Environmental Chemistry and Ecotoxicology, Book of Abstracts. p. 48-48.

KLÁN, P., KLÁNOVÁ, J., HOLOUBEK, I. Phototransformations of Organic Compounds in Water Ice. In SECOTOX, 7th Regional Meeting of the Central and Eastern European Section. p. 9-9, 2002.

KLIMEŠ, D., DUŠEK, L., MARŠÁLEK, B., PAVLIŠ, P., REGNER, B. Contribution of biostatistics to the standardized evaluation fo model dose-response curves in experimental ecotoxicology-software adris, version 1.00. In SECOTOX 2002, Trends and Advances in Environmental Chemistry and Ecotoxicology,Book and Abstracts. p. 173-173.

KOSUBOVÁ, P., GRABIC, R., HOLOUBEK, I. Toxaphene congeners levels in various matrices from the Czech environment. In Conference SECOTOX East 2002, 7th Regional Meeting of the Central and Eastern European Section, Trends and Advances In Environmental Chemistry and Ecotoxicology, Book of Abstracts appendix. p. 7-9.

MACHALA, M., BLÁHA, L., VONDRÁČEK, J., KAPPLOVÁ, P., SOVADINOVÁ, I., PLÍŠKOVÁ, M., MÁJKOVÁ, Z., BREINEKOVÁ, K., LEHMLER, H.-J., ROBERTSON, L.W. Non-genotoxic effects of hydroxy-PCBs and PCB-quinones in liver and mammary in vitro models. In Book of Abstracts - The 2nd PCB Workshop: Recent Advances in the Environmental Toxicology and Health Effects of PCBs Emphasis on the latest advances and the perspective of Central and Eastern Europe. Brno, CR, 07-11/05/2002. p. 119-119.

MACHALA, M., NEČA, J., CIGANEK, M., BLÁHA, L., JANOŠEK, J., KAPPLOVÁ, P., BINKOVÁ, B., VONDRÁČEK, J. Chemical profile and contribution of PAHs to in vitro toxic potencies of urban particulate matter samples. In SETAC Europe 12th Annual Meeting (Abstract Book). p. 134-134, 2002.

MACHALA, M., VONDRÁČEK, J., BLÁHA, L., MINKSOVÁ-CHRAMOSTOVÁ, K., NEČA, J., CIGANEK, M. Nongenotoxic modes of action of polycyclic aromatic hydrocarbons and their relative potencies in rat liver cellular models. Ecotoxicological significance of individual compounds in abiotic samples. In Book of Abstracts - SECOTOX 2002, Trends and Advances in Environmental Chemistry and Ecotoxicology, Brno, 14-16/10/2002. p. 99-100.

MARŠÁLEK, B., BABICA, P., BLÁHA, L. Human health risks of cyanobacterial toxins (microcystins) in Brno reservoir. In SECOTOX 2002, Trends and Advances in Environmental Chemistry and Ecotoxicology, Book of Abstracts. p. 117-121.

MARŠÁLEK, B. Ekotoxikologické biotesty: Rozdělení, přehled, použití (Ecotoxicological Biotests - overview, categorization, applications). In Sborník pracovní konference - Ekotoxikologické Biotesty I, Seč u Chrudimi, 18-19/9/2002. p. 8-24.

MATOUŠEK, J. Health and environmental problems of using anti-armour munitions containing depleted uranium core. (54. Sjezd Chemických Společností) Chemické Listy, Praha : Česká společnost chemická, 96(S), 1, p. 302-303, 2002.

MATOUŠEK, J., MANOVÁ, J., VÁLKOVÁ, P. Biotransformation of some organic energetics and toxicity of products in aquatic environment. (54. Sjezd Chemických Společností) Chemické Listy, Prague : Česká společnost chemická, 96(S), 1, p. 285-286, 2002.

MATOUŠEK, J. Toxicological and radiotoxicological problems of using anti-armour munitions containing depleted uranium. (54. Sjezd Chemických Společností) Chemické Listy, Praha : Ceská společnost chemická, 96, 1, p. 503-503, 2002.

MATOUŠEK, J. Old scrap chemical munitions and toxic armaments wastes in the Central-European and Baltic regions. In Book of Abstracts - SECOTOX 2002, Trends and Advances in Environmental Chemistry and Ecotoxicology, Brno, 14-16/10/2002. p. 246-252.

MATOUŠEK, J. Stockholm convention on persistent organic pollutants (2001) and its relation to other international agreements. In Book of Abstracts - SECOTOX 2002, Trends and Advances in Environmental Chemistry and Ecotoxicology, Brno, 14-16/10/2002. p. 230-233.

MATUŠKA, P., PILAŘOVÁ, O., MERTA, Z., SKŘIČKOVÁ, J., DUŠEK, L. The influence of co-morbidity on the outcome of non-invasive ventilatory support in patients with acute respiratory failure (ARF) in chronic obstructive pulmonary disease (COPD). In 1st Central European Congress on Intensive Care Medicine. p. 49-50, 2002.

PICER, M., HOLOUBEK, I. PCBs in the environment of Slovenia and Croatia as consequence of their accidental release. In Book of Abstracts - The 2nd PCB Workshop: Recent Advances in the Environmental Toxicology and Health Effects of PCBs Emphasis on the latest advances and the perspective of Central and Eastern Europe. Brno, CR, 07-11/05/2002. p. 7-7.

ŠKAREK, M., ČUPR, P., FLEGROVÁ, Z. Experimentální možnosti detekce genotoxického potenciálu (Experimental detection of genotoxic potential). In Sborník pracovní konference - Ekotoxikologické Biotesty I, Seč u Chrudimi, 18-19/9/2002. p. 93-107.

ŠKAREK, M., ČUPR, P., FLEGROVÁ, Z., VAN DYK, T.K. Evaluation of the SOS genotoxicity test - RecA test - a bioluminescence screening tool for the short-term detection of genotoxicity. In SECOTOX - 7th Meeting of the Central and Eastern European Regional Section, Book of Abstracts Appendix. p. 11-14, 2002.

ŠVIHÁLEK, J., HOFMAN, J. Functional Diversity of Soil Microbial Communities around an Industrial Source. In Book of Abstracts - SECOTOX 2002, Trends and Advances in Environmental Chemistry and Ecotoxicology, Brno, 14-16/10/2002. p. 212-215.

TANIYASU, S., KANNAN, K., HOLOUBEK, I., ANSORGOVÁ, A., HORII, Y., HANARI, N., YAMASHITA, N. Isomer-specific analysis of PCN and dioxin-like compounds in DELORs, technical PCB mixtures from former Czechoslovakia. In Book of Abstracts - The 2nd PCB Workshop: Recent Advances in the Environmental Toxicology and Health Effects of PCBs Emphasis on the latest advances and the perspective of Central and Eastern Europe. Brno, CR, 07-11/05/2002. p. 40-40.

UPHAM, B.L., BLÁHA, L., VONDRÁČEK, J., MACHALA, M. Inhibition of gap junctional intercellular communication and the activation of mitogen activated protein kinase by PCBs depends on substitution of chlorine ortho-position. In Book of Abstracts - The 2nd PCB Workshop: Recent Advances in the Environmental Toxicology and Health Effects of PCBs Emphasis on the latest advances and the perspective of Central and Eastern Europe. Brno, CR, 07-11/05/2002. p. 118-118.

ŽALOUDÍK, J., DUŠEK, L., MUŽÍK, J., PAVLIŠ, P., KOPTÍKOVÁ, J., SVOBODNÍK, A., GERYK, E., VYZULA, R., ABRAHÁMOVÁ, J. Využití dat NOR pro kontrolu kvality onkologické péče - studie vybraných skupin nádorů podpořená software SVOD (Application of NOR data for quality control of oncological care - study of selected tumor groups supported by SVOD software). In Sborník - XXVI. Brněnské onkologické dny, Brno 29.5. - 31.5. 2002. p. 70-78.


UNEP Chemicals/GEF Holoubek, I. (Regional co-ordinator for Europe): UNEP Chemicals/GEF Project Regionally Based Assessment of Persistent Toxic Substances UNIDO/GEF Holoubek, I.: Enabling activities to facilitate early action in the implementation of the Stockholm Convention on Persistent Organic Pollutants (POPs Convention) in Czech Republic 5th Framework Programme of EU Holoubek, I. - "RECETOX" - Center of Excelence for Environmental Chemistry and Ecotoxicology (kontrakt No. EVK1-2002-00519) Holoubek, I. - "APOPSBAL" - Assessment of the selected POPs (PCBs, PCDD/Fs, OCPs) in the atmosphere and water ecosystems from the waste materials generated by warfare in former Yugoslavia (kontrakt No. ICA2-CT-2002-10007)

Holoubek, I. - Dioxins and PCBs - Environmental Levels and Human Exposure in Candidate Countries (kontrakt No. ENV.C.2/SER/2002/0085)

Polar Programme of Norway I. Holoubek, P. Klán: Polar Programme, Expedition Svalbarg - The Photochemistry of PBT Compounds in Ice Grant Agency of the Czech Republic 525/00/D101 Bláha, L.: In vitro methods for studies of epigenetic toxicity of xenobiotics

205/02/0896 Holoubek, I.: Photochemistry of persistent organic compounds in water ice and on its surface Grant Agency of the Ministry of Education, Youth and Sport MŠMT:FRVŠ 786/2002 Hofman, J.: Adaptation of soil microbial biomass on positive and negative changes MŠMT:FRVŠ 745/2002 Holoubek, I.: Laboratory for Studies of Environmental Processes MŠMT:FRVŠ 755/2002 Kosubová, P. Optimalization of toxaphen analyses in environmental matrices. (supervisor: J. Klánová)

Governmental Council for Science and Research CR / Ministry of the Environment CR CEZJ 0714 0003 Holoubek, I.: Environment, Carcinogenesis, Oncology VaV/340/1/00 Holoubek, I.: Region specific approaches in the analysis of ecological risks – methodology of assessment in the relationships to the natural catastrophes VaV/340/1/01 Holoubek, I.: Effects of environmental pollution to the contanination and quality of biotic components of ecosystems. Subproject: Photochemistry of organic polutants in wax layer from the needles surfaces VaV/740/2/01 Holoubek, I.: Transformations of atmospheric pollutants in the relationships to the negative anthropogenic processes, their effects on human population, landscape receptors and modelling of atmospheric transport

VaV/740/5/00 Holoubek, I.: Evaluation of ecosystem and health risks of heavy metals and persistent organic pollutants in the relationships to the obligations of CR from Convention CLRTAP VaV/740/1/02 Holoubek, I.: The investigation of measures effectivnes concerning to the limitation of air pollution based on reduction of negative effects of pollutants to the environmental compartments and human health

CONFERENCES (SYMPOSIA, SEMINARS) ORGANIZED BY THE DEPARTMENT MEMBERS

The 2nd Technichal Workshop on effects and transboundary movement of persistent toxic substances (Project UNEP/GEF Regionally-Based Assessment of Persistent Toxic Substances) 19-23/2/2002, Göteborg, Sweden (Holoubek I. - Chair of Organizing Committee, other staff of RECETOX - organizers)

The Second PCB Workshop - Recent Advances in the Environmental Toxicology and Health Effects of PCBs. 7-11/5/2002, Brno, Czech Republic (Holoubek I. - Chair of Organizing Committee, other staff of RECETOX - organizers)

Regional Priority Setting Meeting - Europe (Project UNEP/GEF Regionally-Based Assessment of Persistent Toxic Substances), 28/5-1/6/2002, Průhonice, Czech Republic (Holoubek I. - Chair of Organizing Committee, other staff of RECETOX - organizers)

7th Regional Meeting of the Central and Eastern European Section "SECOTOX 2002" - Trends and Advances in Environmental Chemistry and Ecotoxicology. 14-16/10/2002, Brno, Czech Republic (Holoubek I. - Chair of Organizing Committee, other staff of RECETOX - organizers)

NATIONAL AND INTERNATIONAL AWARDS OF THE STAFF MEMBERS

Holoubek, I. Silver medal of Faculty of Chemistry, Technical University, Brno (10th anniversary of the faculty establishment)

Matoušek, J. Gold medal of Faculty of Chemistry, Technical University, Brno (10th anniversary of the faculty establishment); Diploma and selection for publication in "Great Minds of the 21st Century", American Biographical Institute, U.S.A.; Diploma and selection for publication in "2000 Outstanding Europeans of the 21st Century", International Biographical Centre, Cambridge, U.K.

INVITED LECTURES AND RESEARCH STAYS OF STAFF ABROAD

Čupr, P. et al. Applications of in vitro tests for screening of genotoxicity of environmental samples. National Conference "Industrial Toxicology and Ecotoxicology", Kouty nad Desnou, 3.-7.6.2002 (invited lecture, in Czech).

Dušek L. et al. Universal standard for evaluation of dose-response curves. National Conference Ecotoxicological Biotests, Seč u Chrudimi, 18.-19.9., 2002 (invited lecture, in Czech).

Dušek L. et al. Ecotoxicological Biotess in expert system for complex evaluation of ecological risks - Project IDRIS II. National Conference Ecotoxicological Biotests, Seč u Chrudimi, 18.-19.9. 2002 (invited lecture, in Czech).

Holoubek I. The European initiatives in persistent toxic substances assessment. Workshop on Technologies and Processes for Sustainable Development and Pollution Reduction/Prevention. Brno, Czech Republic, 14.-16.1.2002 (invited lecture).

Holoubek I. Persistent, bioaccumulative and toxic substances – sources, environmental levels and risks. Conference Hazardous Chemicals and Environmental Safety. Moscow, Russia, 6.-8.3.2002 (invited lecture).

I. Holoubek: Integrated monitoring of POPs – the comparison of the contamination on the regional and locals levels. 3rd EMEP Workshop of Task Force on Measurements and Modelling. WMO Geneva, Switzerland, 19.-22.3.2002 (invited lecture).

I. Holoubek et al:: The emission inventory of PAHs, PCBs, PCDDs/Fs, HCB in the Czech Republic. Workshop on the Determination of Dioxin in Industrial Emissions. Brno, Czech Republic, 16.-19.4.2002 (invited lecture).

Holoubek I. et al. Projects on implementation of Stockholm convention. National Conference "Industrial Toxicology and Ecotoxicology", Kouty nad Desnou, 3.-7.6.2002 (invited lecture, in Czech).

I. Holoubek: Survey on ongoing activities in the field of remediation of POPs in CEE countries. Workshop on Remediation Technologies Application for Heavily Polluted Sites in CEE Countries. Bratislava, Slovakia, 24.-26.6.2002 (invited lecture).

Maršálek, B. Early warning and prediction of cyanobacterial water blooms. Porto University, Portugal, 28.2-1.3. 2002 (invited lecture)

Maršálek, B. Cyanobacteria and the cyanotoxins - detection, prediction and prevention. National Institute of Health, Bratislava, Slovakia, 18.11.2002 (invited lecture)

Maršálek, B. Cyanobacterial toxins. District Hygiene Institute, Michalovce, Slovakia, 23.5. 2002 (invited lecture)

Matoušek, J.: Health and environmental problems of using anti-armour munitions containing depleted uranium core. EuPRA Conference: Europe as a Peaceful Power? Burg Stadtschlaining, Austria, 13.-17.7.2002 (invited lecture)

Matoušek, J.. Assistance and Protection – One of the main pillars of the Chemical Weapons Convention: Access of the Czech Republic to the Article X of the Convention. NATO-RTA-SAS Panel Symposium on Defensive Aspects of Chemical and Biological Warfare, Delft, Netherlands, 5.6.2002 (invited lecture)

Matoušek, J..: Threats posed to the Chemical Wepons Convention by the new toxic chemicals and the importance of implementing the CWC´s General Purpose Criterion. NATO-ARW: Maximizing the Security Benefits from the First Review Conference of the Chemical Weapons Convention, Bratislava, Slovakia 21.-27.1. 2002 (invited lecture)

Matoušek, J.: Banning chemical weapons – forever. NGO Committee for Peace, UNO Vienna, 19.3.2002 (invited lecture)

Matoušek, J.: Personal decontamination within the rescue measures following terrorist chemical, biological and radiological attacks. NATO-ARW: Technology for Combating WMD Terrorism, Baltimore - Hunt Valley, USA, 19.-22.11.2002 (invited lecture) OTHER INTERNATIONAL CONTACTS AND CO-OPERATION OF STAFF

Based on the previous activities of EERO (European Environmental Reseach Organization), ESF (European Scientific Foundation) and the 5th Framework Programme of European Union (RECETOX - Center of Excellence, kontrakt EVK1-2002-00519) Network on Persistent, Bioaccumulative and Toxic chemicals (ESF Network on PBTs Chemicals) was established with the following scientific and research topics: ♦ the fate of PBTs in the European region - source inventories, emission/deposition processes, long-range

transport, transformation processes and bioavailability of PBTs in terrestrial ecosystems, modeling of chemical fate in the environment at the local, regional and global scale with special attention to new types of chemicals and those for which inadequate monitoring data exist;

♦ the developing of new sampling and analytical methods for PBTs; ♦ the study of effects on various types and levels of biota with special attention to study of effects of

environmental mixtures and study of ”unknown” effects – study of phytotoxic effects, effects on soil microbial populations and soil fauna, effects on aquatic biota, the developing of mechanism-based biomarkers of effect, study of non-genotoxic carcinogenesis;

♦ ecological risk assessment – reliable monitoring data are needed for risk assessment and model calibrations. Research centre RECETOX is the co-ordination centre of this network. ESF Network on PBTs compounds includes 15 European and US universities and research institutes. Research activities of RECETOX cover the Czech participation on EMEP Programme of UN ECE Convention CLRTAP and completely performed the regional background monitoring of persistent, toxic substances in the area of Košetice observatory of Czech Hydrometeorological Institute.

At present, RECETOX as a part of R-T&A is the implementation agency of Stockholm Convention in the Czech Republic (GEF/UNIDO project Enabling activities to facilitate early action in the implementation of the Stockholm Convention on Persistent Organic Pollutants (POPs Convention) in Czech Republic). Also RECETOX participates on the UNEP/GEF Project Regionally Based Assessment of Persistent Toxic Substances (co-ordination of region III - Europe).


Holoubek, I.: member of UNEP/IFCS – POPs Protocol – regional experts group – Regional Co-ordinator of GEF Regionall Based Assessment on Persistent Toxic Substances; member of UN/ECE – Task Force for Measurements and Modelling, Task Force on Emission Inventories; member of SETAC - Society of Environmental Chemistry and Toxicology; member of SECOTOX - Society of Ecotoxicology and Chemical Safety - member of Central and Eastern Europen Regional Committee; member of Society for Risk Analysis; chairman of the Czech Society for Environmental Chemistry and Ecotoxicology, member of Scientific Council of Masaryk Oncological Institute; person responsible for Environmental Risk Assessment (Ministry of the Environment); member of Working group Biology and Ecology, Commission for Accreditation, Ministry of Education, Youth and Sport; member of sub-commission for Chemistry, Grant Agency, CR; chairman of the council of Ph.D. study Environmental Chemistry MU Brno, member of the council of Ph.D. study Environmental Chemistry VUT Brno, member of the council of Ph.D. study Ecology MU Brno, member of the council of Ph.D. study Food chemistry and analysis VŠCHT Praha, Ecology and Applied Ecology Charles University, Praha; member of editorial board Air Protection (CR), member of editorial board Environmental Science and Pollution Research, Acta Hydrobilogica et Hydrochimica, and Fresenius Environmental Bulletin.

Dušek, L.: Chief manager of the Center of Biostatistics and Analyses, Faculty of Medicine and Faculty of Science, Masaryk University, Brno; member of the Pedagogical and Acreditation Advisory boards, Faculty of Science, Masaryk University, Brno; member of the Czech Society for Environmental Chemistry and Ecotoxicology; member of the Czech Society for Analytical Cytometry

Maršálek, B.: vice-chairman of the Czech Algological Society, member of the council of MSc. studies Ecotoxicology, Masaryk University, member of the council of PhD study of Environmental Chemistry, Masaryk University, Brno, member of the Ph.D. council of Hydrobiology, Masaryk University, Brno

Matoušek, J.: World Federation of Scientific Workers (WFSW) - member of Standing Committee on Disarmament, accredited representative of the WFSW at UNO Office in Vienna, accredited representative of the WFSW in the Conference of NGOs (CONGO). International Network of Engineers and Scientists (INES), Dortmund, Brussels - member of INES Executive Committee, member of INES Council, regional representative for Czechia, Slovakia, Austria, Hungary, Slovenia, Croatia, Romania, Bulgaria, Bosnia and Herzegovina, Yugoslavia and FYR Macedonia in INES. Pugwash Conferences on Science and World Affairs, Boston, London, Rome, Geneva - contact person of the Pugwash Council for the Czech Republic. European Peace Research Association (EuPRA) - founding member. Helsinki CitizensÁssembly - founding member. International Institute for Peace, Vienna - member of the Association and Visiting Professor. Organisation for the Prohibition of Chemical Weapons (OPCW), The Hague - member of Scientific Advisory Board. International Trade Unions (Dublin) Committee for Peace and Disarmament, Glasgow - member of Scientific Advisory Board. American Biographical Institute, Raleigh, NC - member of Research Advisory Board. International Biographical Centre, Cambridge, UK - member of Research Council. Grant Agency of the Czech Republic - member of the subcommission for Technical Chemistry. State Authority for Nuclear Safety, Prague, CR - member of Research Advisory Board. Institute for Protection of Population, Lázně Bohdaneč, CR - member of Scientific Advisory Board. Czech Chemical Society - member of Committee of Brno Branch. Technical University Brno, Faculty of Chemistry - honorary member of Scientific Council, member of Educational Advisory Board, member of the board for Doctoral Studies of Environmental Chemistry and Technology; member of the Commission for PhD Examinations in Environmental Chemistry and Technology. Military Academy, Brno,CR - member of Educational and Advisory Committee for Doctoral Study of Theory of State Defence. Masaryk University, Brno, Faculty of Science - member of educational advisory committee for Doctoral Studies of Ecology, vice-chairman of educational advisory committee for Doctoral Study of Environmental Chemistry, Alterning chairman of state Commission for PhD examinations in Environmental Chemistry, member of state commission for MSc examinations in Environmental Chemistry.

Laboratory of Atomic Spectrochemistry


The Laboratory provides research possibilities to students of doctoral study programmes Chemistry and Physics. The Laboratory staff participates also in teaching of students of chemistry and physics of bachelor´s and master´s study programmes. Educational activities comprise the semestrial lecture and seminar on analytical chemistry for students involved in teaching career in chemistry, semestrial lectures on analytical molecular spectrometry, spectrophotometry, analytical atomic spectrometry, spectrometry with inductively coupled plasma, plasma spectrometry, lasers in analytical chemistry, and measurement and automation. The personnel of the Laboratory is involved in laboratory exercise of analytical chemistry for students of biology, laboratory exercise concerning the methods of chemical research, and spectrometric methods for special exercise in analytical chemistry. Diploma and bachelor´s theses are focused on development of atomic emission spectrometry methods of elemental analysis using atomic spectrometry instruments i.e. two ICP spectrometers, a flame-emission high-resolution spectrometer, a pulsed laser for vaporization of solid samples, and plasma-jet excitation source. Laboratory cooperates with the Department of Analytical Chemistry and with the Plasmachemical Laboratory of the Section Physics and the Department of Physical Electronics of the Section Physics.

In the year 2002, research activities were focused on fundamental aspects of laser ablation inductively coupled plasma atomic emission spectrometry (LA-ICP-AES), on the LA-ICP-AES analysis of tungsten carbide ceramics, steels, glass, agricultural soils, scoria and milk powder. Energy distribution in the crossection of the laser beam was studied. Equipment for laser induced breakdown spectrometry, ICP atomic fluorescence spectrometry and RTG fluorescence spectrometry was installed in the laboratory. Development of hydride generation technique was carried out using ICP-AES for the determination of trace concentrations of selenium. Non-spectral interferences and mechanism of excitation of selenium atoms in ICP were studied. Development of device for UV-photolysis of samples with organic matrix, such as biological materials, animal or human tissues, whole blood, blood serum, plants or foodstuff was continued. Research and development of the high-frequency plasma jet and the microwave plasma torch were continued in co-operation with Plasmachemical laboratory. Development and application of method for the analysis of human bones from ancient skeletal residues were carried out for the Department of Anthropology of the Faculty of Science. Solution analysis with ICP-AES was concentrated on the determination of elements in samples of agricultural soils monitoring in co-operation with the State Agricultural Institute for Supervising and Testing. Vacuum UV spectral region was investigated with the aim of spectrochemical determination of sulphur, phosphorus, and iodine. ICP-AES methods for determination of iodine and sulfur with generation of volatile compounds were investigated.

LABORATORY STAFF

Head: Vítězslav Otruba (Associate Prof., RNDr., CSc.) Scientific Workers: Vladimír Aubrecht (Associate Prof., RNDr., CSc.), Technical University Brno,

Masaryk University Brno Viktor Kanický (Associate Prof., RNDr., D.Sc.) Vratislav Kapička (Prof., RNDr., D.Sc.) Research Workers: Karel Novotný (Mgr., Ph.D.) Jiří Machát (Mgr., Ph.D.) Technical Assistants: Pavel Krásenský (Ing.) Jan Mikoláš (Mgr.) – till February 2002 Věra Stuchlíková (Ing.) – till March 2002 Iveta Lekešová (Ing) Eva Niedobová (Mgr.) – part time Jan Píše – part time Secretary: Iva Šafaříková Ph.D. Students: Full time: Jiří Machát (Mgr.) Martin Semerád (Mgr.) Markéta Vašková (Mgr.)

Eva Niedobová (Mgr.) Aleš Hrdlička (Mgr.) Lubomír Prokeš (Ing.) Jitka Studýnková (Mgr.) Miloš Halúzka (Mgr.) Part time: Marie Pištěková (RNDr.) Martin Štěpán (Mgr.)


Diploma Theses:

Jaroslav Šebela – Inductively coupled plasma – optical emission spectrometry with laser ablation in analysis of glass (supervisor: K. Novotný)

Petr Šenk – Inductively coupled plasma – optical emission spectrometry with laser ablation in analysis of steels (supervisor: V. Otruba)

Tomáš Vaculovič – The influence of additional gases in inductively coupled plasma – optical emission spectrometry and laser ablation in analysis of steels (supervisor: V. Kanický)

PhD Thesis

Jiří Machát – Interferences in ICP spectrometry of biological materials and sample preparation (supervisor: V. Otruba) LIST OF PUBLICATIONS Scientific papers BRABLEC, A., SLAVÍČEK, P., KLÍMA, M., KAPIČKA, V., BEHNKE, J.F., ŠÍCHA, M. Comparison of the barrier-torch discharge and torch discharge at atmospheric pressure. Czech. J. Phys., Praha : Institute of Physics Academy of Sciences, 2002, 52, p. 561-566.

MACHÁT, J., KANICKÝ, V., OTRUBA, V. Determination of Selenium in Blood Serum by Inductively Coupled Plasma Atomic Emission Spectrometry with Pneumatic Nebulization. Analytical and Bioanalytical Chemistry, Heidelberg : Springer, 372, 4, p. 576-581, 2002.

MACHÁT, J., OTRUBA, V., KANICKÝ, V. Spectral and non-spectral interferences in determination of selenium by inductively coupled plasma atomic emission spectrometry. Journal of analytical atomic spectrometry, Cambridge : Royal Society of Chemistry, 17, 9, p. 1096-1102, 2002.

MIKOLÁŠ, J., MUSIL, P., STUCHLÍKOVÁ, V., NOVOTNÝ, K., OTRUBA, V., KANICKÝ, V. Infrared laser ablation study of pressed soil pellets with inductively coupled plasma atomic emission spectrometry. Analytical and Bioanalytical Chemistry, Heidelberg : Springer, 374, 2, p. 244-250, 2002.


MACHÁT, J., OTRUBA, V., KANICKÝ, V. Matrix interferences in determination of selenium by inductively coupled plasma - atomic emission spectrometry. In 2002 Winter Conference on Plasma Spectrochemistry. p. 224-225.

NOVOTNÝ, K., ŠEBELA, J., OTRUBA, V., KANICKÝ, V. Využití rychlé sekvenční ICP spektrometrie pro analýzu ocelí ve spojení s laserovou ablací (Using of a rapid sequential ICP spectrometry with laser ablation for the analysis of steels). In Hutní analytika 2002. p. 15-19.

SLAVÍČEK, P., BRABLEC, A., KAPIČKA, V., KLÍMA, M., KOUSAL, J. Diagnostics of barier torch discharge burning at atmospheric pressure. In 21st SPIG Contributed papers. p. 470-473, 2002.

VACULOVIČ, T., NOVOTNÝ, K., KANICKÝ, V., OTRUBA, V. The influence of atmosphere composition in the ablation chamber on the analysis of steels by inductively coupled plasma atomic emission spectrometry LA-ICP-AES. In Book of Abstracts XVI-th Slovak Spectroscopic conference. p. 49-49, 2002.

Other professional publications

KANICKÝ, V., LUBAL, P., HAVEL, J. SPEKTROFOTOMETRICKÉ STUDIUM SOLVATAČNÍCH ROVNOVÁH URANU(VI) S N, N - DIMETHYLFORMAMIDEM. CHEMICKÉ LISTY, Praha : Česká společnost chemická, 96, 6, p. 474-474, 2002.

MACHÁT, J., OTRUBA, V., KANICKÝ, V. Spectral and non-spectral interferences in determination of selenium by inductively coupled plasma - atomic emission spectrometry. In XVIth Slovak spectroscopic conference. Book of abstracts. p. 39-39, 2002.

NIEDOBOVÁ, E., KANICKÝ, V., OTRUBA, V. Determination of iodine in biological samples by ICP-OES in VUV region. Praha (Czech Republic) : Česká společnost chemická, 96(S), Symposiap. 303-305, 2002.

PROKEŠ, L., KANICKÝ, V., OTRUBA, V. Elemental analysis of the skeletal remains of two Moravian population groups from the Great Migration Period. Chemické listy, 96, Symposia, p. S308, 4 pp, 2002.

SEMERÁD, M., MACHÁT, J., NIEDOBOVÁ, E., ČÁP, R. Using Statistica software and artificial neural networks for optimisation of working conditions in various spectroscopic analysis. In International Chemometric Conference - CHEMOMETRICS VI, 2002.


Grant Agency of the Czech Republic 203/00/0415 Responsible holder: Masaryk University Brno, Laboratory of Plasma Sources for Chemical Analysis of the faculty of Sciences. Kanický, V., Otruba, V., Novotný, K., Mikoláš, J.: The study of interaction of laser radiation with pressed powdered materials for laser ablation inductively coupled plasma atomic emission spectrometry. Special materials, ceramic powders, agricultural soils, geological samples, solid wastes are studied with methods of atomic emission, electron and laser spectroscopy.

Ministry of Education, Youth and Sports of the Czech Republic CEZ: J07/98: 143100003 Otruba, V., and co.: Laboratory of Atomic Spectrochemistry. A project of research of plasma discharges as excitation sources for spectral analysis. Programme of doctoral studies in analytical chemistry.

Grant Agency of the Czech Republic 203/02/P097 Novotný K.: The study of interaction of laser radiation with solid materials by plasma spectrometry methods INVITED LECTURES AND RESEARCH STAYS OF STAFF ABROAD

Kanický V.: invited lecture, University of Cordoba, Department of Physics, May, 2002.

Kanický V.: invited lecture, XV th Slovak Spectroscopic Conference, Košice, Slovensko, June, 2002.

Kanický, V.: research stay (3 weeks) at Laboratoire des Sciences Analytiques, Université Claude Bernard - Lyon I, Villeurbanne, France.

Kanický, V.: research stay (1 week) at Departamento de Fisica, Universidad de Cordoba, Cordoba Spain.

Otruba, V.: research stay (3 weeks) at Laboratoire des Sciences Analytiques, Université Claude Bernard - Lyon I, Villeurbanne, France.

Otruba, V.: research stay (1 week) at Departamento de Fisica, Universidad de Cordoba, Cordoba Spain.

Kanický V.: research stay (2+2 weeks) at Swiss Federal Institute of Technology, Zurich, Swiss.

OTHER INTERNATIONAL CONTACTS AND CO-OPERATION

Cooperation

University of Beograd, Yugoslavia, (Prof. N. Konjevic, Kapička)

Université Claude Bernard - Lyon I, Laboratoire des Sciences Analytiques, Lyon, France (J.-M. Mermet; V. Kanický, V. Otruba).

Veterinary and Agrochemical Research Centre, Section of Ecochemistry and Spectroscopy, Tervuren, Belgium (M. Hoenig, V. Otruba, V. Kanický)

Technical University Košice, Faculty of Metallurgy, Department of Chemistry, Košice, Slovak republic (Prof. E. Krakovská, Otruba, Kanický)

University of Vienna, Dept. of Analytical Chemistry, Division of Atomic Spectroscopy, Vienna, Austria (Prof. I. Steffan, Kanický, Otruba)

Lina Spark Applications, S.a., Cully, Switzerland (Dipl. Ing. Wilfried Vogel, Kanický, Otruba)

Departamento de Fisica, Universidad de Cordoba. (Prof. Dr. M. Carmen Quintero Ortega, Otruba, Kanický).

Institut für Analytische Chemie, Abteilung Atomspektroskopie, Fakultät für Naturwissenschaften und Mathematik, Univesrität Wien. Spolupráce v oblasti atomové spektrochemie prvků (Univ. Prof. Dr. Ilse Steffan).

Departamento de Química Analítica, Facultad de Estudios Superiores Cuautitlán, Universidad Autonoma de Mexico, (Dr. A. L. Revilla Vazquez, Kanický, Otruba).

Adam Mickiewicz University, Department of Water and Soil Analysis, Poznan, Poland (Prof. J. Siepak; V. Kanický, K. Novotný).

Eidgenossische Technische Hochschule, Department of Inorganic Chemistry, Zürich, Switzerland, (Prof. D. Guenther; V. Kanický).

Foreign visitors

Alma Luisa Revilla Vazquez, Departamento de Química Analítica, Facultad de Estudios Superiores Cuautitlán, Universidad Autonoma de Mexico, two-week stay


Miloš Halúzka (Mgr.), Laboratoire des Sciences Analytiques, Université Claude Bernard - Lyon I, Villeurbanne, France, 3 months, granted by SOCRATES/ERASMUS project, PhD.

Aleš Hrdlička (Mgr.), Departamento de Fisica, Universidad de Cordoba, Spain, 3 months, granted by SOCRATES/ERASMUS project, PhD.

Jitka Studýnková (Mgr.), Laboratoire des Sciences Analytiques, Université Claude Bernard - Lyon I, Villeurbanne, France, 3 months, granted by SOCRATES/ERASMUS project, PhD.

Tomáš Vaculovič (Mgr.), Laboratoire des Sciences Analytiques, Université Claude Bernard - Lyon I, Villeurbanne, France, 3 months, granted by SOCRATES/ERASMUS project, PhD.


Aubrecht, V.: Teaching at the Faculty of Science, Masaryk University and the Faculty of Electrical Engineering, Technical University, Brno: Electrical Discharges.

Kanický, V.: Member of the Council for Postgraduate Students (Analytical Chemistry); Head (alternating) of the Analytical Chemistry Board of Examiners for Ph.D. study; Member of the Committee of the Spectroscopic Soc. of J. M. Marci, Prague; Vice-chairman of the Working Party of Analytical Chemistry of the Czech Chemical Society; Vice-dean of the Faculty of Science.

Kapička, V.: Member of the Scientific Council of the University Ostrava and South Bohemia, České Budějovice and Biophysical Institute, Academy of Sciences of Czech Republic, Brno. Member of working group of Grant Agency, Academy of Science and Grant Agency of Czech Republic. Member of the Council for the Postgraduate Study in Plasma Physics at the Faculty of Applied Physics, the University Plzeň, the Faculty of Mathematics and Physics, Charles University, Prague, and the Faculty of Sciences, Masaryk University, Brno. Member of the Council for the postgraduate study in applied physics, the Faculty of Science, Palacký University, Olomouc.

Otruba, V.: Member of the Council for Postgraduate Students (Analytical Chemistry); Member of the Spectroscopic Society of J. M. Marci, Prague.

Documents

Chemistry Year – Book 2002 · (analytical chemistry, biochemistry, environmental chemistry, inorganic chemistry, macromolecular chemistry, organic chemistry and physical chemistry)