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SYSTEMSSYSTEMSPR

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Future ofFuture of

BIOCHEM GENETICS CELL BIO.MOL. BIO

STEM

CELLS,

CLONING

REC. DNA

CELL

TYPE

3DSTRUCTURE

FERTILI-

ZATION

SYSTEMS

VIRUSES

IMMUNE

LIFELIFE

NERVOUSCANCER

2

STARTSTARTFOUNDATIONSFOUNDATIONS

How-to 1How-to 1 FO

RM

AT

ION

FO

RM

AT

ION

How-to 2How-to 2

SYSTEMSSYSTEMSPR

OB

LE

MS

PR

OB

LE

MS

Future ofFuture of

BIOCHEM GENETICS CELL BIO.MOL. BIO

STEM

CELLS,

CLONING

REC. DNA

CELL

TYPE

3DSTRUCTURE

FERTILI-

ZATION

PRIONS

VIRUSES

CANCER

LIFELIFE

IMMUNE NERVOUS

BIOCHEM GENETICS

3

Student question of the day

Q: What makes an allele recessive?

A: Alleles in isolation are not dominant or

recessive; phenotypes are dominant or

recessive.

Alleles contribute to “pea shape”:

Genotype Phenotype Dominance

SS smooth smooth >

Ss smooth wrinkled

ss wrinkled4

http://www.humanillnesses.com/original/Se-Sy/Sickle-cell-Anemia.html

5Purves 10.7 6

Chromosomal Chiasmata

7http://www.sciencemag.org/cgi/content/full/287/5461/2216 8Alfred Sturtevant 1891- 1970

http://www.nature.com/ng/journal/v34/n3/full/ng0703-242.html

9http://www.sciencemag.org/cgi/content/full/287/5461/2216

C.B. Bridges, 1937, 5 Mb of DNA on tip of Drosophila Chr. 2

10

Terms

• Dominant phenotype

• Recessive phenotype

• Incomplete dominance

• Dihybrid cross

• Mendel’s 2nd Law

• Linkage

• Linkage group

• Loci

• Crossing over

• Chiasmata

• Recombinants

• Genetic Map

• Centimorgan (cM)

• Map Unit

• Recombination Frequency

• Genetic Distance

• Physical Distance

• Meosis I

• Meosis II

• Chromosomal theory