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Circulatory Systems
Chapter 34
2Circulatory SysCirculatory Systemstems
OutlineOutline
Transport in InvertebratesTransport in InvertebratesOpen versus Closed Circulatory Open versus Closed Circulatory SystemsSystems
Transport in VertebratesTransport in VertebratesTransport in HumansTransport in Humans
HeartbeatHeartbeatVascular PathwaysVascular PathwaysBlood PressureBlood Pressure
Cardiovascular DisordersCardiovascular DisordersBloodBlood
ComponentsComponentsClottingClotting
3Circulatory SysCirculatory Systemstems
Transport in InvertebratesTransport in Invertebrates
Small aquatic animals with no circulatory Small aquatic animals with no circulatory systemsystemMay rely on external water in May rely on external water in gastrovascular cavity to service cellsgastrovascular cavity to service cells
Roundworms and other pseudocoelomatesRoundworms and other pseudocoelomatesUse a fluid-filled body cavity as a means of Use a fluid-filled body cavity as a means of transporting substancestransporting substances
Fluid-filled cavity can also act as a Fluid-filled cavity can also act as a hydrostatic skeleton hydrostatic skeleton
Animals that have a rigid skeletonAnimals that have a rigid skeletonMay still rely on body fluids for the May still rely on body fluids for the purpose of locomotionpurpose of locomotion
Bivalves pump hemolymph into the foot Bivalves pump hemolymph into the foot for digging into mudfor digging into mud
4Aquatic OrganismsWithout a Circulatory
System
5Circulatory SysCirculatory SystemstemsOpen vs. ClosedOpen vs. Closed
Invertebrate CirculationInvertebrate CirculationTwo types of circulatory fluids:Two types of circulatory fluids:
Blood - contained within blood vesselsBlood - contained within blood vessels Hemolymph - flows into hemocoelHemolymph - flows into hemocoel
Open Circulatory SystemOpen Circulatory System Heart pumps hemolymph via vesselsHeart pumps hemolymph via vessels Vessels empty into tissue spacesVessels empty into tissue spaces
Closed Circulatory SystemClosed Circulatory System Heart pumps blood to capillariesHeart pumps blood to capillaries Gases and materials diffuse to and from Gases and materials diffuse to and from nearby cellsnearby cells
Vessels return blood to heart without it Vessels return blood to heart without it contacting tissuescontacting tissues
6Open vs. Closed Circulatory Systems
7Circulatory SysCirculatory Systemstems
Transport in the VertebratesTransport in the VertebratesAll vertebrates have a closed cardiovascular All vertebrates have a closed cardiovascular systemsystem
Vertebrate heart:Vertebrate heart: Atrial chamber(s) of heart receive blood from Atrial chamber(s) of heart receive blood from general circulationgeneral circulation
Ventricle chamber(s) of heart pump blood out Ventricle chamber(s) of heart pump blood out through blood vesselsthrough blood vessels
Vertebrate vessels:Vertebrate vessels: Arteries - Carry blood away from heartArteries - Carry blood away from heart Arterioles – Lead to capillariesArterioles – Lead to capillaries Capillaries - Exchange materials with tissue Capillaries - Exchange materials with tissue fluidfluid
Venules - Lead to veinsVenules - Lead to veins Veins - Return blood to heartVeins - Return blood to heart
8Transport in Birds and Mammals
9Comparison of Circulatory Circuits
in Vertebrates
10Circulatory SysCirculatory SystemstemsComparison of Circulatory Comparison of Circulatory
PathwaysPathwaysFish - Blood flows in single loopFish - Blood flows in single loop
Single atrium and single ventricleSingle atrium and single ventricle
Amphibians - Blood flows in double Amphibians - Blood flows in double looploop
Two atria with single ventricleTwo atria with single ventricle
Other vertebrates - Blood flows in a Other vertebrates - Blood flows in a double loopdouble loop
Heart divided by septum into separate Heart divided by septum into separate sidessides
11Circulatory SysCirculatory Systemstems
Transport in HumansTransport in Humans
Human HeartHuman Heart
Fist-sizedFist-sized
Cone-shapedCone-shaped
Very muscular organ (special cardiac Very muscular organ (special cardiac fibers)fibers)
Lies within a fluid-filled sac (the Lies within a fluid-filled sac (the pericardium)pericardium)
12Circulatory SysCirculatory SystemstemsHuman Heart:Human Heart:
Gross AnatomyGross Anatomy
Septum separates heart into left & Septum separates heart into left & right halvesright halves
Each half has two chambersEach half has two chambers
Upper two chambers are the atriaUpper two chambers are the atria
Thin-walledThin-walled
Receive blood from circulationReceive blood from circulation
Lower two chambers are the ventriclesLower two chambers are the ventricles
Thick-walledThick-walled
Pump blood away from heartPump blood away from heart
13External Heart Anatomy
14Internal View of the Heart
15Circulatory SysCirculatory SystemstemsHuman Heart:Human Heart:
ValvesValves
Valves open and close to control blood Valves open and close to control blood flow through heartflow through heart
Atrioventricular valves Atrioventricular valves
TricuspidTricuspid
BicuspidBicuspid
Semilunar valvesSemilunar valves
PulmonaryPulmonary
AorticAortic
16Circulatory SysCirculatory Systemstems
Transport in HumansTransport in HumansBlood returning to heart from systemic circuitBlood returning to heart from systemic circuit
Enters right atriumEnters right atrium Right atrium pumps through tricuspid valve to Right atrium pumps through tricuspid valve to right ventricleright ventricle
Right ventricle pumps blood through Right ventricle pumps blood through pulmonary valve to the pulmonary circuitpulmonary valve to the pulmonary circuit
Blood returning to heart from pulmonary Blood returning to heart from pulmonary circuitcircuit Enters left atriumEnters left atrium Left atrium pumps through mitral valve to left Left atrium pumps through mitral valve to left ventricleventricle
Left ventricle pumps blood through aortic Left ventricle pumps blood through aortic valve to the systemic circuitvalve to the systemic circuit
Oxygen-poor blood never mixes with oxygen-Oxygen-poor blood never mixes with oxygen-rich blood (in humans)rich blood (in humans)
17Circulatory SysCirculatory Systemstems
HeartbeatHeartbeatSystole - Contraction of heart chambersSystole - Contraction of heart chambersDiastole - Relaxation of heart chambersDiastole - Relaxation of heart chambersPulse - Two-part pumping action that takes Pulse - Two-part pumping action that takes about a secondabout a second Blood collects in atria, the atria contractBlood collects in atria, the atria contract Pushes blood through tricuspid and mitral Pushes blood through tricuspid and mitral valves into the resting lower ventriclesvalves into the resting lower ventricles
This phase (the longer of the two) is called the This phase (the longer of the two) is called the diastolediastole
Second part begins when ventricles fillSecond part begins when ventricles fill Ventricles contractVentricles contract This is called systoleThis is called systole
After blood moves into the pulmonary artery After blood moves into the pulmonary artery and aorta, the ventricles relaxand aorta, the ventricles relax
18Conduction System of the Heart
19Circulatory SysCirculatory Systemstems
HeartbeatHeartbeatRhythmic contraction due to cardiac Rhythmic contraction due to cardiac conduction systemconduction system
Sinoatrial node (SA) keeps the heartbeat Sinoatrial node (SA) keeps the heartbeat regularregular
Atrioventricular node (AV) signals ventricles Atrioventricular node (AV) signals ventricles to contract - Purkinje Fibersto contract - Purkinje Fibers
Electrocardiogram (ECG)Electrocardiogram (ECG)
A recording of electrical changes that A recording of electrical changes that occurring in myocardium during cardiac occurring in myocardium during cardiac cyclecycle
When SA node triggers an impulse, the When SA node triggers an impulse, the atrial fibers produce an electrical charge (P atrial fibers produce an electrical charge (P wave)wave)
20Circulatory SysCirculatory Systemstems
Vascular PathwaysVascular Pathways
Human cardiovascular system includes Human cardiovascular system includes two major circular pathways:two major circular pathways:
Pulmonary CircuitPulmonary Circuit
Takes oxygen-poor blood to the lungs Takes oxygen-poor blood to the lungs and returns oxygen-rich blood to the and returns oxygen-rich blood to the heartheart
Systemic CircuitSystemic Circuit
Takes blood throughout the body from Takes blood throughout the body from the aorta to the vena cavathe aorta to the vena cava
21Path of Blood
22Velocity and Blood Pressure
23Cross Section of a Valve in a Vein
24Circulatory SysCirculatory Systemstems
Blood PressureBlood PressureThe beat of the heart supplies pressure The beat of the heart supplies pressure that keeps blood moving in the arteriesthat keeps blood moving in the arteriesSystolic Pressure results from blood Systolic Pressure results from blood forced into the arteries during ventricular forced into the arteries during ventricular systolesystole
Diastolic Pressure is the pressure in the Diastolic Pressure is the pressure in the arteries during during ventricular diastolearteries during during ventricular diastole
Skeletal muscle contraction pushes blood Skeletal muscle contraction pushes blood in the veins toward the heartin the veins toward the heart
Blood pressureBlood pressureNormally measured with a Normally measured with a sphygmomanometer on the brachial arterysphygmomanometer on the brachial artery
Expressed in the form: Systolic “over” Expressed in the form: Systolic “over” DiastolicDiastolic
25Circulatory SysCirculatory Systemstems
Cardiovascular DisordersCardiovascular DisordersHypertension - High blood pressureHypertension - High blood pressure
Atherosclerosis - Accumulation of fatty Atherosclerosis - Accumulation of fatty materials in inner linings of arteriesmaterials in inner linings of arteries
Stroke - Cranial arteriole bursts or is Stroke - Cranial arteriole bursts or is blocked by an embolusblocked by an embolus
Heart attack – (Myocardial infarction) Heart attack – (Myocardial infarction) Coronary artery becomes partially Coronary artery becomes partially blockedblocked
Angina pectoris – Painful squeezing Angina pectoris – Painful squeezing sensation from myocardial oxygen sensation from myocardial oxygen insufficiencyinsufficiency
26Circulatory SysCirculatory SystemstemsBlood:Blood:
Homeostasis FunctionsHomeostasis Functions
Transports substances to and from Transports substances to and from capillaries for exchange with tissue capillaries for exchange with tissue fluidfluid
Guards against pathogen invasionGuards against pathogen invasion
Regulates body temperatureRegulates body temperature
Buffers body pHBuffers body pH
Maintain osmotic pressureMaintain osmotic pressure
Clots prevent blood/fluid lossClots prevent blood/fluid loss
27Circulatory SysCirculatory Systemstems
Red Blood CellsRed Blood Cells
Small, biconcave disksSmall, biconcave disks
Lack a nucleus and contain hemoglobinLack a nucleus and contain hemoglobin
Hemoglobin containsHemoglobin contains
Four globin protein chainsFour globin protein chains
Each associated with an iron-containing Each associated with an iron-containing hemeheme
Manufactured continuously in bone Manufactured continuously in bone marrow of skull, ribs, vertebrae, and marrow of skull, ribs, vertebrae, and ends of long bonesends of long bones
28Circulatory SysCirculatory Systemstems
White Blood CellsWhite Blood Cells
Most types larger than red blood cellsMost types larger than red blood cells
Contain a nucleus and lack hemoglobinContain a nucleus and lack hemoglobin
Important in inflammatory responseImportant in inflammatory response
Neutrophils enter tissue fluid and Neutrophils enter tissue fluid and phagocytize foreign materialphagocytize foreign material
Lymphocytes (T Cells) attack infected Lymphocytes (T Cells) attack infected cellscells
Antigens cause body to produce Antigens cause body to produce antibodiesantibodies
29Composition of Blood
30Circulatory SysCirculatory Systemstems
PlateletsPlatelets
PlateletsPlatelets
Result from fragmentation of Result from fragmentation of megakaryocytesmegakaryocytes
Involved in coagulationInvolved in coagulation
Blood clot consists of:Blood clot consists of:
PlateletsPlatelets
Red blood cellsRed blood cells
All entangled within fibrin threadsAll entangled within fibrin threads
31Blood Clotting
32Circulatory SysCirculatory Systemstems
Capillary ExchangeCapillary Exchange
Capillaries very narrow – Tiny RBCs Capillaries very narrow – Tiny RBCs must go through single filemust go through single file
Wall of capillaries very thin to Wall of capillaries very thin to facilitate diffusion of nutrients, facilitate diffusion of nutrients, gasses and wastesgasses and wastes
Oxygen and nutrients exit a capillary Oxygen and nutrients exit a capillary near the arterial endnear the arterial end
Carbon dioxide and waste molecules Carbon dioxide and waste molecules enter a capillary near the venous endenter a capillary near the venous end
33Capillary Exchange
34Capillary Bed
35Circulatory SysCirculatory Systemstems
ReviewReview
Transport in InvertebratesTransport in InvertebratesOpen versus Closed Circulatory Open versus Closed Circulatory SystemsSystems
Transport in VertebratesTransport in VertebratesTransport in HumansTransport in Humans
HeartbeatHeartbeatVascular PathwaysVascular PathwaysBlood PressureBlood Pressure
Cardiovascular DisordersCardiovascular DisordersBloodBlood
ComponentsComponentsClottingClotting
Circulatory Systems
Ending Slide Chapter 34