19
 Cluster of Orthologous Cluster of Orthologous Groups (COGs) Groups (COGs) Harold Ardila Harold Ardila Carlos A. Niño Carlos A. Niño

Cluster of orthologous Groups (COGs)bioinf.ibun.unal.edu.co/cbib/estudiantes/1-07/expoEst/COGs.pdf · Clusters of Orthologous Groups of proteins (COGs) were delineated by comparing

  • Upload
    others

  • View
    9

  • Download
    0

Embed Size (px)

Citation preview

Page 1: Cluster of orthologous Groups (COGs)bioinf.ibun.unal.edu.co/cbib/estudiantes/1-07/expoEst/COGs.pdf · Clusters of Orthologous Groups of proteins (COGs) were delineated by comparing

    

Cluster of Orthologous Cluster of Orthologous Groups (COGs)Groups (COGs)

Harold ArdilaHarold Ardila

Carlos A. NiñoCarlos A. Niño

Page 2: Cluster of orthologous Groups (COGs)bioinf.ibun.unal.edu.co/cbib/estudiantes/1-07/expoEst/COGs.pdf · Clusters of Orthologous Groups of proteins (COGs) were delineated by comparing

     

COGsCOGs• Ortólogos son genes que se encuentran en Ortólogos son genes que se encuentran en

diferentes especies y provienen de un gen diferentes especies y provienen de un gen ancestral común. Generalmente presentan la ancestral común. Generalmente presentan la misma función a través de la evolución.misma función a través de la evolución.

Page 3: Cluster of orthologous Groups (COGs)bioinf.ibun.unal.edu.co/cbib/estudiantes/1-07/expoEst/COGs.pdf · Clusters of Orthologous Groups of proteins (COGs) were delineated by comparing

     

COGsCOGs

• Cada COG se define como el grupo de tres Cada COG se define como el grupo de tres o más proteínas que son o más proteínas que son OrtólogasOrtólogas

• Han sido desarrollados mediante la Han sido desarrollados mediante la comparación, todos contra todos, de comparación, todos contra todos, de secuencias de proteínas codificadas en secuencias de proteínas codificadas en genomas completos secuenciados, genomas completos secuenciados, utilizando el programa BLAST.utilizando el programa BLAST.

• 5666 COGs (unicelulares)5666 COGs (unicelulares)

• 4852 KOGs (eucariotas)4852 KOGs (eucariotas)

Page 4: Cluster of orthologous Groups (COGs)bioinf.ibun.unal.edu.co/cbib/estudiantes/1-07/expoEst/COGs.pdf · Clusters of Orthologous Groups of proteins (COGs) were delineated by comparing

     

ACCESO

Page 5: Cluster of orthologous Groups (COGs)bioinf.ibun.unal.edu.co/cbib/estudiantes/1-07/expoEst/COGs.pdf · Clusters of Orthologous Groups of proteins (COGs) were delineated by comparing

     

Page 6: Cluster of orthologous Groups (COGs)bioinf.ibun.unal.edu.co/cbib/estudiantes/1-07/expoEst/COGs.pdf · Clusters of Orthologous Groups of proteins (COGs) were delineated by comparing

     

1 2

1.COGs – UNICELULARES

2.KOGs - EUCARIOTES

Page 7: Cluster of orthologous Groups (COGs)bioinf.ibun.unal.edu.co/cbib/estudiantes/1-07/expoEst/COGs.pdf · Clusters of Orthologous Groups of proteins (COGs) were delineated by comparing

     

Phyla

ORDEN

Taxonomy DB

Page 8: Cluster of orthologous Groups (COGs)bioinf.ibun.unal.edu.co/cbib/estudiantes/1-07/expoEst/COGs.pdf · Clusters of Orthologous Groups of proteins (COGs) were delineated by comparing

     

Page 9: Cluster of orthologous Groups (COGs)bioinf.ibun.unal.edu.co/cbib/estudiantes/1-07/expoEst/COGs.pdf · Clusters of Orthologous Groups of proteins (COGs) were delineated by comparing

     

Page 10: Cluster of orthologous Groups (COGs)bioinf.ibun.unal.edu.co/cbib/estudiantes/1-07/expoEst/COGs.pdf · Clusters of Orthologous Groups of proteins (COGs) were delineated by comparing

     

Page 11: Cluster of orthologous Groups (COGs)bioinf.ibun.unal.edu.co/cbib/estudiantes/1-07/expoEst/COGs.pdf · Clusters of Orthologous Groups of proteins (COGs) were delineated by comparing

     

Page 12: Cluster of orthologous Groups (COGs)bioinf.ibun.unal.edu.co/cbib/estudiantes/1-07/expoEst/COGs.pdf · Clusters of Orthologous Groups of proteins (COGs) were delineated by comparing

     

Page 13: Cluster of orthologous Groups (COGs)bioinf.ibun.unal.edu.co/cbib/estudiantes/1-07/expoEst/COGs.pdf · Clusters of Orthologous Groups of proteins (COGs) were delineated by comparing

     

EUKARIOTIC ORTHOLOGOUS GROUPS KOGs

Page 14: Cluster of orthologous Groups (COGs)bioinf.ibun.unal.edu.co/cbib/estudiantes/1-07/expoEst/COGs.pdf · Clusters of Orthologous Groups of proteins (COGs) were delineated by comparing

     

Page 15: Cluster of orthologous Groups (COGs)bioinf.ibun.unal.edu.co/cbib/estudiantes/1-07/expoEst/COGs.pdf · Clusters of Orthologous Groups of proteins (COGs) were delineated by comparing

     

EUKARIOTIC ORTHOLOGOUS GROUPS KOGs

Page 16: Cluster of orthologous Groups (COGs)bioinf.ibun.unal.edu.co/cbib/estudiantes/1-07/expoEst/COGs.pdf · Clusters of Orthologous Groups of proteins (COGs) were delineated by comparing

     

EUKARIOTIC ORTHOLOGOUS GROUPS KOGs

Page 17: Cluster of orthologous Groups (COGs)bioinf.ibun.unal.edu.co/cbib/estudiantes/1-07/expoEst/COGs.pdf · Clusters of Orthologous Groups of proteins (COGs) were delineated by comparing

     

próximamente … próximamente …

Page 18: Cluster of orthologous Groups (COGs)bioinf.ibun.unal.edu.co/cbib/estudiantes/1-07/expoEst/COGs.pdf · Clusters of Orthologous Groups of proteins (COGs) were delineated by comparing

     

Equipo COGEquipo COG

Eugene V. KooninEugene V. KooninSenior InvestigatorSenior InvestigatorNational Center for Biotechnology Information (NCBI)National Center for Biotechnology Information (NCBI)National Library of Medicine (NLM)National Library of Medicine (NLM)National Institutes of Health (NIH)National Institutes of Health (NIH)

Page 19: Cluster of orthologous Groups (COGs)bioinf.ibun.unal.edu.co/cbib/estudiantes/1-07/expoEst/COGs.pdf · Clusters of Orthologous Groups of proteins (COGs) were delineated by comparing