CNCR Groupe des Contacts Europe hospitaliers · Develop personalised approaches and clinical tools to predict and prevent diseases by integration of high quality microbiome and other

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CNCR Groupe des Contacts Europe hospitaliers

Réunion générale

52 avenue Maurice Ripoche - Paris 14e

Mardi 27 Juin 2017

Réunion générale des Contacts Europe - 27 Juin 2017 1

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Programme de la Matinée

Réunion générale des Contacts Europe - 27 juin 2017

1° Accueil des participant(e)s- Tour de table des centres présents- Retour sur la formation H2020 du 6 juin 2017

2° Actualités H2020 :- Présentation des futures lignes des programmes de travail

2018, 2019 et 2020- Calendrier 2017 : programme des InfoDays Santé

3° Etats des chantiers en cours :- Chantier 1a. Contacts Europe hospitaliers, forces en présence- Chantier 1b. Participation des établissements aux projets

européens- Chantier 3. Point sur l’identification des coûts des

plateformes- Chantier 5. Capacity Building

4° Autres chantiers à lancero Chantier 6. Groupe Europe hospitalier et lobbyingo Chantier 7. Cartographie des équipes expertes

5° Sujets d’actualité et de travail- Open access aux données médicales / cf rapport- Site internet du CNCR, page partagée- Formation et/ou kit : « Entrer dans un premier projet

européen »- Validation des dépôts de projets au sein des

établissements- Autres points (tbc)

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Programme de l’après-midi

12h00 - 13h00 : Déjeuner pris en charge pour l’ensemble des participant(e)s par le CNCR


6° Retour sur la Formation H2020 et travail sur le canevas « Expert »

Thibaut Vanrietvelde, ANR, PCN H2020 juridique et financier

7° Présentation des instruments H2020 PCP/PPI et des projets reliés

Louis Potel et Charles-Edouard Escurat, RESAH

8° Présentation des programmes H2020 ERCChristine Durieux, Inserm, PCN H2020 ERC

9° Tour de table et fin de la journée

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Actualité H2020

Réunion générale des Contacts Europe - 27 Juin 2017

Health, demographicchange and well-being

Food security and bioeconomy

Secure, clean and efficient Energy

Smart, green and integratedtransport

Climate action

Inclusive, innovativeand reflective societies

Secure societies

EXCELLENT

SCIENCE

INDUSTRIAL

LEADERSHIP

SOCIETAL

CHALLENGES

Marie Sklodowska Curie Actions

ERC European Research Council

FETFuture Emerging Technologies

Research Infrastructures

Key Enabling Technologies• TIC• NMBPNanotechnologies, Advanced materials, Biotechnology, Advance manufacturing and processing, Photonics, Microelectronics

• Espace

Access to risk finance

Innovation in SMEs

PILIER 1 PILIER 2 PILIER 324,4 Md€ 17,0 Md€ 29,7 Md€

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H2020, structure du WP 2018-2020

Call 1. Better Health and care, economic growth and sustainable health systems, (21 lines, 11 CSA)

Call 2. – Digital transformation in Health and Care (8 lines, 5 CSA)

Call 3. – Trusted digital solutions and Cybersecurity in Health and Care (2 lines, 1 CSA)

Budget 2018-2019923 M€

Budget 2018-2019 186,6 M€

Budget 2018-201971M€

1.1 Personalised medicine

1.2 Innovative health and care industry

1.3 Infectious diseases and improving global health

1.4. Innovative health and care systems - Integration of care

1.5 Decoding the role of the environment for health and well-being

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Horizon 2020, WP 2018-2020 santé, draft


Programme de travail en 3 ansSeulement les titres des appels 2020 sont connus, toujours en discussion et seront publié courant 2018

Call 2018 en 1 étape seulement (clôture le 10 avril 2018)Sauf pour le BHC-15-2018 (2 étapes) « Maladies infectieuses négligées »

Appels larges basés sur des défis de société

Ligne pilote « lump sum » : BHC-15-2018La CE teste une nouveau mode de financement par somme forfaitaire- Budget complet détaillé par work package et par bénéficiaire lors de la proposal- Expert financier dans le comité d’évaluation- Budget du projet négocié et signé dans le grant agreement avant le début du projet plus de justification financière- Attention, tous les détails et conditions ne sont pas encore connus à ce jour

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1.1 Personalised MedecineBudg.Projet

BudgetTotal

Type

BHC-03 2018Exploiting research outcomes and application potential of the human microbiome for personalised prediction and prevention of disease

13-14 50 RIA

Develop personalised approaches and clinical tools to predict and prevent diseases by integration of high quality microbiome andother -omics data produced by large scale initiatives- Production of new data to deliver more valuable tools- Related topics in SC2 and IMI

BHC-05 2018International flagship collaboration with Canada for human data storage,integration and sharing for developing personalised medicine approaches

6 40 RIA

Improving international collaboration in data repositories, developing models and methods for data deposition, curation andexchange procedures (interoperability).- Multidisciplinary approach is key aspect- Several independent projects funded but “could” be coordinated by an existing consortium

BHC-01 2019 Understanding causative mechanisms in co- and multimorbities 4-6 70 RIA

Identify causative mechanisms combining mental and physical disorders via the integration of Basic, pre-clinical and/or clinicalresearch (clinical trials excluded)- Biomarkers development for diagnostic and monitoring- Continuation of PHC-3 (WP 2014-2015)

BHC-02 2019 Systems approaches for the discovery of combinatorial therapies 4-6 50 RIA

Build more sophisticated computational framework to predict patient responses to combinatorial therapies : pre-clinical and clinical validation- Project focus on marketed therapeutic intervention and/or products in final stage of development (phase 1 and 2 excluded)-Drug repurposing is included in the scope

10 avril 18

10 avril 18

02 Oct. 18 - 09 Apr. 19

02 Oct. 18 - 09 Apr. 19

Call 1. Better Health and care, economic growth and sustainable health systems

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Horizon 2020, WP 2018-2020 santé, draftCall 1. Better Health and care, economic growth and sustainable health systems

1.2 Innovative Health care industryBudg.Projet

BudgetTotal

Type

BHC-09 2018 Innovation platforms for advanced therapies of the future 12-15 50 RIACreation of knowledge and exploitation platforms around innovative concepts for advanced therapies-To build possible new therapeutic approaches-Component : Basic biology and its mode of action, proof-of-concept, safety, efficacy etc …- Business model to exploit results, outreach and public information activities- Advanced therapies definition : EC Regulation 1394/2007

BHC-07 2019 Regenerative medicine : from new insights to new applications 6-8 50 RIADevelop regenerative processes to address unmet clinical needs of large patient group-Explain how the approach is regenerative-Any step of the innovation chain-Conventional method or device alone are excluded- Show how it will be delivered to patient, potential exploitation and regulatory aspects

BHC-10 2019 Innovation Procurement : Next generation sequencing (NGS) for routine diagnosis 9-11 40 PCP

HCO-05 2018 Strenghten regulatory sciences and support for successful regulatory scientific advice 1-2 2 CSA

10 avril 18

09 avril 19


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1.3 Infectious diseases and improving global healthBudg.Projet

BudgetTotal

Type

BHC-15 2018 New anti-infective agents for prevention and/or treatment of neglected infectious diseases (NID) 5-10 45 RIA

The call targets the Neglected infectious diseasesFurther development of vaccines and/or drugs candidates- bridge the gap between preclinical and clinical development - help advance already existing candidates along the development pipeline- Neglected viral disease excluded- Participation of disease endemic countries

BHC-16 2018 Global Alliance for Chronic Disease (GACD) 1 - 20 RIA

BHC-21 2018Research on HIV and/or tuberculosis and/or hepatitis C in patients with mono-, co-infections or comorbidities in the contest of the collaboration between the European Union and the Russian Federation

- 10 RIA

TB: To investigate biomarkers or new diagnostic tests for early screening of TB risk groups for TB infection and identification ofantimicrobial drug resistance.HIV: To investigate the susceptibility to HIV and/or disease progression rate after infection, including various HIV serotypes, development of genetically-defined adverse effects (AE) during antiretroviral therapy (ART) and concomitant diseases (comorbidities and co-infections, including with tuberculosis).HCV: To evaluate the genetic determinants of the virus and the host, comorbid conditions that can be involved in disease progression and HCV treatment strategies.- Address one or more subtopics- Use of already established European cohort networks - Comorbidities of HIV or TB infections with non-communicable diseases (NCDs) should be considered

06 Fev. 18 - 04 sep 18

10 avril 18

10 avril 18

10


BHC-13 2018 Mining big data for early detection in infectious disease threats driven by climate change and other factors 12-15 30 RIADevelopment of technology which allows the pooling, access analysis and sharing of relevant dataInnovative bioinformatics and modelling methodologies (risk modelling and mapping)Ready to use Analytical tools for early warning, risk assessment and monitoring of (re)emerging infectious diseases threats- Data from a wide range of relevant sources (NGS, surveillance data, societal data)- Data privacy and Data security must be taken into account

BHC-14 2019 Stratified host-directed approaches to improve prevention and/or treatment of infectious disease 6-10 95 RIA

To develop novel therapeutic or preventive approaches on the basis of specific factors identified in the host or the host-pathogen interactionStratification of individuals based on theses characteristics and tailor the treatment or the preventive measure accordinglyTo test emerging concepts in drug and/or vaccine development in order to address the problem of antimicrobial drug resistance and to optimize therapeutic, curative or preventive measures against infectious diseases of major concern for Europe- Differences in factors such as age, gender and genetic variation among the human population should be taken into consideration- The proposals should focus on late pre-clinical and/or clinical research

BHC-18 2019 EU-CELAC collaboration for research on non-communicable diseases 1-3 22 RIATo support EU-CELAC research networks addressing common healthcare challenges and supporting data sharing and capacity building, in the area of non-communicable diseases

BHC-19 2019 Implementation research for maternal and child health 2-4 25 RIA

New or improved health service delivery interventions that strengthen maternal and child health; The scaling up and/or adapting of existing interventions to new contexts- Proposals should focus on implementation research for improving maternal and child health during the first '1000 days' from pregnancy until two years of age- Neither pre-clinical research nor clinical trials in the context of product development are within the scope of this call

10 avril 18

02 Oct. 18 - 09 Apr. 19

10 avril 18

02 Oct. 18 - 09 Apr. 19

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1.4 Innovative health and care systems - Integration of care Projet Total Type

BHC-23 2018 Novel patient centered approaches for survivorship, palliation and/or end-of-life care 3-4 40 RIADemonstrate effectiveness and cost-effectiveness of new, improved or specifically adapted pharmacological or non-pharmacologicalintervention to relieve symptoms and suffering caused by :- Life threatening non-communicable disease- Serious late and long term side effect of disease treatments in patients and survivor- Symptoms that occur at the end of lifeRandomized clinical trial/observational studies to be considered

BHC-26 2018 HTA research to support evidence-based healthcare 8-10 10 ?Develop new or improved approaches and framework to address- Specific types or groups of health technologies- Selected therapeutic areas- Use of real-world dataEffort should be directed at implementation of methodological work in the 3 areas

BHC-22 2019 Mental Health in the workplace 2-4 30 RIADevelop and implement intervention(s) that employer/organization can take to promote good mental health and prevent mental illnessin the workplace- Co-morbidities to be addresses- Unpaid work and work at home include in the scope

BHC-25 2019 Demonstration pilots for implementation of Personalised Medicine in health care 15-20 60 RIADemonstrate the benefit for individuals as well as the implementability and economic viability of PM approaches in real life healthcare settingsDiseases with high burden to societyUse of big data and HPCEngage partners (region or cities) having adopted PM approaches already

HCO-12 2018Innovation in health care – a CSA towards using pre-commercial procurement and public procurement of innovative solutions in health care systems

2 2 CSA

10 avril 18

10 avril 18

02 Oct. 18 - 09 Apr. 19

02 Oct. 18 - 09 Apr. 19

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Horizon 2020, WP 2018-2020 sané, draftCall 1. Better Health and care, economic growth and sustainable health systems

1.5 Decoding the role of the environment for health and well-beingBudg.Projet

BudgetTotal

Type

BHC-27 2018 New testing and screening methods to identify endocrine disrupting chemicals 4-6 50 RIAIncrease the quality and efficiency of existing methods to meet demanding and evolving regulatory requirements worldwide research should improve and harmonise screening and testing protocols/strategies and hazard/risk assessments with better and faster tools, methods or models, including high-throughput and in silico methods - Focus should be on the most urgent regulatory needs (thyroid axis, female reproduction, non-genotoxiccarcinogens and developmental neurotoxicity)- Potential work with JRC to be considered in the proposal

BHC-28 2019The Human Exposome Project : a toolbox for assessing and addressing the impact of environment on health

8-12 50 RIA

Collect, combine and analyze large data sets offering new possibilities to understand the contribution of environmental factors to the global health burden of common chronic diseases identification of the most important environmental risk factors for the development of major NCDs across the life course (including in utero)- Well-designed retrospective epidemiological studies may be included - Creation of a prospective Europe-wide exposomics cohort and biobank, integratingbehavioural, socio-economic factors and clinical records- Coordination mechanism between the projects funded will be required and will be added at the grant preparation stage

10 avril 18

09 avril 19

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Horizon 2020, WP 2018-2020 santé, draftCall 2. Digital Transformation in Health and Care

Budg.Projet

BudgetTotal

Type

DTH-03 2018 Adaptive smart working and living environment supporting active and healthy ageing 3-4 25 RIAProposals should develop and validate digitally enabled adaptive services and solutions leading to smart work environments for older adultsProposals should be based on trans-disciplinary research, involving behavioural, sociological, psychological, medical and other relevant disciplines, including gender and cultural aspects. development and integration of unobtrusive, adaptive solutions for age-friendly living and working environmentsProposals should build on active user engagement in order to ensure the understanding of user needs

DTH -07 2018Exploiting the full potential of in-silico medicine research for personalised diagnostic and therapies in cloud-based environments

10-15 37 RIA

to develop and validate software tools and devices for diagnostic or treatment based on computational modelling and simulation applied in biology and physiologyThe solutions should enable decision making for the choice of drugs, devices or other biomedical products, procedures, interventions, in vitro and in vivo diagnostics methods and tools, or combined diagnostics and treatmentsThe teams are expected to use shared infrastructures and e-infrastructures, building on existing capacity and expertise

DTH-08 2018 Prototyping a cloud-based standardised Personal Health µRecord/Electronic Health Record for Europe 4-6 20 IA

eHealth interoperability standardisation and harmonisationThis research and innovation action is expected to prototype on a larger scaleThe proposal shall demonstrate its ability to providing a cloud-based harmonised/standardised/interoperable health record

17 avril 18

17 avril 18

17 avril 18


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DTH-01 2019Big data and Artificial Intelligence for monitoring health status and quality of life after the cancer treatment

3-5 35 RIA

Improve quality of life after the cancer Proposals should focus and deliver on how to better acquire, manage, share, model, process and exploit big data to effectively monitor health status of individual patients determining and monitoring the combined effects of cancer treatment, environment, lifestyle and genetics on the quality of life, enabling early identification of effects that can cause development of new medical conditions and/or impair the quality of life

DTH-05 2019 Large scale implementation of digital innovation for health and care in an ageing society 2-5 10 PPIto specify, purchase and deploy ICT based solutions (made up of services and ICT products to enable the provision of services) for active and healthy ageing through a common supply and demand side dialogue

DTH-09 2019 Scaling up the univocal Identification of Medicinal products 4-6 19 IAenabling and fostering the use of a common EU medicinal Product repository (ISO IDMP compliant) to fulfil the ePrescription/eDispensation in a cross-border setting use caseInclusion of a wide range of relevant stakeholders and experts including inter alia National Competent Authorities, IT Integrators, producers of ePrescribing, clinical record systems, SDOs

02 avril 19

02 avril 19

02 avril 19

Budg.Projet

BudgetTotal

Type


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DTH-10 2019 Digital health and care services 22 PCPKey challenges that could be addressed are patient empowerment, self-management, patient safety, patient involvement, chronic disease management, diagnosing, hospital logistics, skills and independent livingApplicable ICT domains e.g., telemedicine, mHealth, IoT, shared open source IT-based platforms, etc. as will be defined in the market consultation process

DTH-11 2019 Large Scale pilots of personalised & outcome based integrated care 4-6 20 IAfoster the large-scale pilots for deployment of trusted and personalised digital solutions dealing with Integrated Careto supporting and extending healthy and independent living for older individuals who are facing permanently or temporarily reduced functionality and capabilities

02 avril 19

02 avril 19


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Budg.Projet

BudgetTotal

Type

SU-TDS-01 2018 Toolkit for assessing and reducing cyber risks in hospitals and care centres to protect privacy/data/infrastructures 3-5 35 RIA

to foster large-scale deployment of integrated digital solutions which will bring improved quality of life1) develop and deploy innovative and user-led digital solutions capable of supporting and extending healthy and independent living for older individuals who are facing permanently or temporarily reduced functionality and capabilities2) develop and deploy innovative and user-led solutions building on big data for personalised risk detection, advanced health monitoring and early interventions

SDU-TDS-02 2018 Raising awareness and developing training schemes on cybersecurity in hospitals 1 CSA

Development and implementation of innovative methods, tools, guidelines or best practices addressing the need for cybersecurity in hospitalscyberattacks; innovative cybersecurity measures; cybersecurity in the whole lifecycle of a medical device including hardware with embedded software; standards for security-by-design covering the whole lifecycle of eHealth applications; cybersecurity in remote healthcare provisions including homecare settings; security for cloud solutions supporting healthcare services; cybersecurity for Internet of Things

DT-ICT-12 2019Smart and healthy living at home Focus area "Digitising and transforming European Industry, Platforms and Pilots"

15-20 35 IA

17 avril 18

17 avril 18

23 Oct 18 Platforms for smart living at home that integrate a mix of advances ICT , 2 areas : digital solutions for sustaining healthy and indepenadnt livingPersonalised early risk detection

Call 3. Trusted digital solutions and Cybersecurity in Health and Care


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Horizon 2020, WP 2018-2020, autres drafts

1. From functional ecosystems to healthy food

SFS-1420182019

Personalized Nutrition (long term healthy and sustainable diets)Personalized Nutrition (innovative approaches for dietary assessment)

tbc tdc IA / RIA

H2020 Programme, SC2 Food, Call sustainable food securityProject Budget

Total Budget

Type

Innovating cities for sustainability and resilience

SC-14 2019 Visionary and integrated solutions to improve well-being and health in cities 10 tbc IA

H2020 SC5 Climate, call Greening the economy in line with the SustainableDevelopment Goals (SDGs)

Project Budget

Total Budget

Type

Innovation prizes, innovation policy

Prizen°20

2019Horizon Prize for social Innovation in Europe1.Obesity in children2. Aging population

2M€ 2M€ 1 PRIZE

H2020 Programme, SC6 Europe in a changing worldProject Budget

Total Budget

Type


18

Mobiliser les équipes avant le lancement des calls

Se faire connaitre auprès des investigateurs :

leur adresser les drafts

les inviter aux infoDays

Développer des outils de communication interne

HORIZON 2020Health, demographic change and wellbeingSocietal Challenge 1: WP 2018-2020

De l’idée au Projet

Valerie Handweiler : [email protected]

Sylvie Broussous : [email protected]

Eva Murauer : [email protected]

Odile Bardet : [email protected]

Secteur AAP et Europe [email protected] | 3 96 43 | 3 56 12 | 3 56 11

Contacter la Cellule Europe le plus tôt possible !

Draft H2020 work programme (WP) Info Day CHU Montpellier22 juin 2017

Publication du WP One page proposaloct-nov 2017 oct-nov 2017

4 mois

06 fév 2018

04 sep 2018

T 2018: Submission stage 1

3-4 mois

5-6 mois

ONE STAGE CALLS FOR PROPOSAL TWO STAGE CALLS FOR PROPOSAL

10 avril 2018

Invitation for full proposal

~mai 2018

T 2018: Full proposal submission

4 mois

17-18 mois 02 oct 2018 T 2019: Submission stage 1

~jan 2019

09 avril 2019

12-13 mois

Invitation for full proposal


4 mois

09 avril 2019T 2019: Full proposal submission


10 pages Topic 2018Topic 2019

70 pages

70 pages

70 pagesTopic 2019

70 pagesTopic 2019

17 avril 2018 (CNeT)

23 oct 2019 (CNeT)

© C

HU

M –

Juin

20

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Actualité H2020 Santé, dates à retenir

Date évènement lieu

4 juillet 2017 InfoDay Santé H2020 / futur WP 2018-2020 Paris

28 septembre 2017 Formation ANRT niveau 2 Paris

Novembre 2017 lancement officiel du WP 2018-2020 Paris

21 novembre 2017 Groupe Europe CNCR Paris

7 décembre 2017 Brokerage event H2020 Santé Bruxelles

8 décembre 2017 InfoDay H2020 Santé Bruxelles

Mars / Avril 2018 Premiers dépôts Calls 2018 -


20

Horizon 2020, InfoDays

Réunion générale des Contacts Europe – 27 juin 2017

Dates Ville Contact en région

15-juin [email protected] /

[email protected]

20-juin Lille [email protected]/[email protected]

22-juin Montpellier [email protected]

04-juil Paris [email protected]

10-juil Bordeaux [email protected]

06-juilRennes (retransmis à

Brest)[email protected]

Alice.ruczinski@

11-juil-17 Caen [email protected]

19-sept Lyon [email protected]

26-sept Grenoble [email protected], Virginie

29-sept Limoges [email protected]

12, 19 ou 21 septembre Rouen [email protected]

22 septembre Nantesseptembre Paris Saclay [email protected]

septembre Normandie A retracer

Septembre Strasbourg [email protected]

Fin septembre Nancy

02-oct Marseille [email protected]

Début octobre Besançon [email protected]

Octobre Clermont-Ferrand [email protected]

Première quinzaineOctobre

Nice [email protected]

Calendrier des InfoDays en Région

Consultez d’agenda sur le site H2020

Constatez les PCN

mailto:[email protected]/[email protected]

mailto:[email protected]






mailto:[email protected], Virginie









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Chantiers en cours ou à lancer

3° Etats des chantiers en cours- Chantier 1a. Contacts Europe hospitaliers, forces en présence- Chantier 1b. Participation des établissements aux projets européens- Chantier 3. Point sur l’identification des coûts des plateformes- Chantier 5. Capacity Building

4° Autres chantiers à lancero Chantier 6. Groupe Europe hospitalier et lobbyingo Chantier 7. Cartographie des équipes expertes


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Sujets d’actualité et de travail

5° Sujets d’actualité et de travail

- Open access aux données médicales / cf rapport

- Site internet du CNCR, page partagée

- Formation et/ou kit : « Entrer dans un premier projet européen »

- Validation des dépôts de projets au sein des établissements

- Autres points (tbc)


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Pause repas, offerte par le CNCR

23Réunion générale des Contacts Europe - 27 juin 2017

• Retour sur les sessions de janvier et juin 2017

• Prochaines sessions

• Autres initiatives

• Autres sujets d’intérêt

Thibaut Vanrietvelde, responsable des affaires juridiques et européennes à l’ANRT

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Ateliers ANRT « Aspects financiers des projets H2020 »


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Resah, réseau des acheteurs hospitaliers


Présentation des instruments H2020 PCP/PPI et des projets reliésLouis Potel et Charles-Edouard Escurat, RESAH

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European Research Concil


Présentation des programmes H2020 ERCChristine Durieux, Inserm, PCN H2020 ERC

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Fin de la journée et calendrier 2017

Dates Évènement Europe CNCR lieu

19 septembre 2017 Assemblée Générale du CNCR Paris

28 Septembre 2017 Atelier ANRT, niveau 2 ANRT, Paris

21 Novembre 2017 Groupe Europe Nouveaux locaux du CNCR, Paris 14e

Printemps 2018 Groupe Europe (date à définir) Paris

Été 2018 Groupe Europe (date à définir) Paris

Merci à tous/toutes pour votre participation


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CNCR Groupe des Contacts Europe hospitaliers · Develop personalised approaches and clinical tools to predict and prevent diseases by integration of high quality microbiome and other