cobas® 6500 urine analyzer seriesFully automated urine work area on a modular platform

cobas® 6500 urine analyzer seriesFully automated urine work area on a modular platform

•Thecobas6500urineanalyzerseriessignificantlyimprovesproductivityandefficiencyofurinetestingbyreducingmanualinterventiontoaminimumandoptimizesworkflow.

•cobas6500urineanalyzerseriesprovidesafullyautomatedsolutiononamodularplatformforlaboratoriesprocessing100-1000urinesamplesperday.Thecobas u601analyzerperformsfullyautomatedurinestriptestingandcobas u701analyzerperformsfullyautomatedsedimentmicroscopywiththebenefitofrealimages.

•Bothstand-aloneanalyzers,thecobas u601andthecobas u701analyzerscanbeupgradedon-siteontooneplatformwithautomatedsampletransportationthroughtheentiresystem,withcontinuousloadingofurinesamples.

cobas® 6500 urine analyzer seriesNew dimension in productivity, efficiency, process innovation and consolidation

There are 4 good reasons why the cobas 6500 urine analyzer series offers a new dimension in productivity, efficiency, process innovation and consolidation which are:

•Automation of the gold standard•Precise and secure strip results•Urine work area consolidation•Workflow optimization

Automation of the gold standardFullyautomatedsedimentmicroscopystandardizesallstepsoftheprocessandmirrorsrealimagesintotheresultreportingforobjectiveresults.

Precise and secure strip results50yearsofexperienceandproventeststriptechnologyandperfor-mance.Combinedwithregularimprovementsandongoinginnova-tion,fortrueconfidenceinresults.

Workflow optimizationSignificantlyreducedoperatorintervention,automatedsievetesting,improvedcost,staffandtimemanagementandassistedresultmanagement,tofurtherenhanceefficiencyandproductivityinurinetesting.

Consolidation of urine work areaTrueurineworkareaconsolidationwithfullparametermenu,allresultsononescreenforconvenientvalidation.Fullyautomatedsampleflow,forincreasedproductivityandefficiency.

cobas® 6500 urine analyzer seriesAt a glance

2 cobas u 701 module •Fullyautomatedurinemicroscopyanalysis•Throughputisupto116samples/hour•Captures,retainsandreports15images/sample•Reagentfreedesign,onlyusesdisposablecuvettes

(cobas ucuvette)asconsumables•cobas ucuvette:400cuvette/cassettewithRFID

labelling•Reclassificationfunctionalityallowsoperatorto

reclassifyanyparticle•Operatorcandefinecross-checkandvalidationrules•11parameters:erythrocytes,leukocytes,squamous

epithelialcells,non-squamousepithelialcells,bacteria,hyalinecasts,pathologicalcasts,crystals,yeasts,mucusandsperm

1 cobas 6500 user interface•Operatedon19”touchscreen,designedforeaseof

useandintuitivenavigation•Intuitiveuserinterfacehelpstheoperatorusethe

instrumentcorrectly,andalsomeanseffectiveoperation,lesstrainingrequired,helpingstaffmanagement

•Consolidatesresultsofurinestriptestingandurinemicroscopyimagesontoonescreen,customizedandassistedresultmanagement,improvesTATandoptimizesworkflow

•Userdefinedautomatedsievetesting(reflextesting)–sedimenttestonlyifneeded,savingcostandtime

•ConvenientQCmanagementbyconsolidationofQCdataandresultsonasingleplatform,alltheQCinformationcanbeviewedonscreenincluding“QCchart”withoutanymanualentry

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4 Input buffer 5 Output buffer

•Loadingcapacityof75samples(15racks/tray,5samples/rack),continuousloadingofurinesamples

•Thethroughputofcobas6500(urineworkarea)dependsontherateofsamplesofmicroscopy(upto240samples/hourwithteststripanalysisonly,upto116samples/hourwithmicroscopyanalysisonly)

•Automaticallystartsoperationafterrouting,andpriorityoremergencysamplesloading

3 cobas u 601 module •Fullyautomatedurineteststripanalysis•Throughputisupto240samples/hour•Usesreagentstrip(cobas upack)withascorbicacid

resistance•cobas upack:400strips/casettewithRFIDlabelling•Newtechonologyofphotometerforstripreading:

animagesensor(camerachip)performsreflectancephotometricmeasurementsoneachtestpadofateststripwith4wavelengths.Thenewtechnolgyallowsthedifferentiationofintactandlysederythrocytesupto50E/µL,avoidsthemeasuringfailurescausedbydust,lowsamplevolumeorwrongteststrippositioning,e.g.toassurereliableresults

•12parameters:pH,leukocytes,nitrite,protein,glucose,ketones,urobilinogen,bilirubin,anderythrocytes,gravity,colorandclarity

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cobas u 701 microscopy analyzer improves the gold standard in urine microscopy by standardization and automation of all manual steps, removing operator variability and significantly reducing operator intervention and increasing efficiency.

Automation of the gold standard

Fully automated microscopy: withcobas u701analyzer•resuspendsthesample•pipettessampleintocuvettes•centrifugesthecuvette•captures15imagesofeachcentrifuged

sampleall fully automated, resulting in minimum operator intervention and improving TAT.

Standardized process: •standardizesallstepsoftheprocess•reagent-andcontactfreeoperation•mirrorsrealimageseliminating operator variability resulting in objective results.

Retained microscopy images: •mirrorssedimentimagesintotheresult

screens•documentsobjectivityfor easy review or training further enhancing efficiency.

cobas u 601 urine analyzer automates all manual steps and provides high quality results by proven unique reagent strip technology based on 50 years of experience in urine analysis and innovation, minimizing operator intervention while providing confidence in results.

Precise and secure test strip results

Proven Combur-Test® strip technology: •50yearsofsuccessfulhistoryinurine

diagnostics•comparableresultswithsametechnology

acrossallRocheurinalysissystemsfor efficient back-up and network solutions.

Unique reagent strip construction: •ascorbicacidresistanceforprovenhigh

qualityresults•nylonmeshensuresuniformcolor

developmentthroughuniformpenetrationoftheurineintothetestarea

•separatingdifferentreagentpapersinatestpad

protected results, reduced reaction time and increased storage life of the strip by proven design.

New generation of strip test system: •innovationwiththenewphotometer

technologyfortheteststripresultreadingtakinginhomogenous,high-resolutionimagesofeachpad

•detectingtheintactandlysederythrocytesaccurate, safe results by new technology.

Ease of use:•convenientcassetteconcept• cobas u pack,humidityprotected•withRFIDtechnologyminimizing operator intevention and enhancing productivity.

The cobas® 6500 urine analyzer series is a fully automated solution and consolidates the urine work area – fully automated urine microscopy and urine testing – into one single platform standardizing the entire testing procedure resulting in increased productivity and efficiency.

Consolidation of urine work area True modularity: •stand-aloneanalyzerscanbeintegrated

ontoonesingleplatformatsitefor flexible consolidation of testing disciplines.

True integration: •consolidationoffullparametermenuof

urinetesttripandurinemicroscopyfor increased productivity.

Convenience in validation: •allresultsononescreenfor convenient and fast validation.

Fully automated sample flow: •onesampleloadingandonesample

unloadingareaeliminating operator intervention.

Workflow optimization in cobas® 6500 urine analyzer series is the result of using the cassette concept and offering centralized and assisted result management, reducing operator intervention and optimizing the overall laboratory workflow.

Workflow optimization

Efficient cost management: •automatedsievetesting–sedimentistested

onlyifneededbasedontheresultfromstriptesting

reduced cost by optimized workflow setting.

Reagent free cassette concept:•400stripsinonehumidityprotectedcassettesignificantly reduces operation intervention while ensuring high quality of results.

Intuitive software navigation: •effectiveoperationandtrainingsaving time and improving staff mangement.

Assisted result management: •automatedresultvalidationandreflextesting•easyreviewprocessimproves TAT and optimizes workflow.

Reduced and improved maintenance: •reagentfreeoperation•fullycontrolledreloadingofallmaterialsclean operation and less intervention, saves time and gains efficiency.

Harmonized sample handling: •usingstandard5-positionracksincreasing workflow efficiency throughout the entire lab network.

The cobas® 6500 urine analyzer series is an important part of the overall Roche product portfolio and is the result of many years of experience and innovation in the urine testing field.

Rochewithitsstrongcommitmenttoinnovateinthediagnosticfieldisnotonlycontinuouslydevelopingnewproducts,butalsointegratesthemintotheentireportfoliotoprovideavaluablesolutionaddressingthechallengesintoday’slaboratories.Theideaofusingacassetteconcepttohelpreducingoperatorintervention,andofofferingmodularapproachestoprovideflexibility,hasbeen

implementedthroughouttheRocheportfolio.Also,theRoche5positionrackisusedinallanalyzersforClinicalChemistry,Immunochemistry,forserumworkarea,forpre-andpost-analyticalsystemsandforlaboratoryautomation,aswellasonthecobas6500urineanalyzerseriessothatnewanalyzerscanbeintegratedintothelabworkingprocesssmoothly.

Serum work area

Pre- and post-analytics

Hematology

Coagulation

Urinalysis

Point of Care

Automation of the gold standard Precise and secure strip results

Workflow optimization Consolidation of urine work area

The cobas 6500 urine analyzer series offers a wide range of benefits for laboratories with demanding challenges.

The cobas® 6500 urine analyzer series standardizes the entire testing procedure, reduces operator intervention and offers centralized result management. This optimizes the overall laboratory workflow and helps increasing the efficiency in productivity.

cobas® 6500 urine analyzer seriesTechnical specifications

System Modular,analyticalsystemplatform,consolidatedworkareaforurinestriptestandurinemicroscopy,expandableandre-configurableonsite

Types of modules cobas u 601module:urinestripmeasuringunitcobas u 701module:urinemicroscopymeasuringunit

Module combinations Stand-alone:•cobas u 601urineanalyzer•cobas u 701microscopyanalyzerUrineworkarea:•cobas6500urineanalyzerserieswithonecobas u601moduleandonecobas u 701module

Sample throughput Upto240samples/hourwithteststripanalysisonlyUpto116samples/hourwithmicroscopyanalysisonlyThethroughput(theoreticalmax)dependsontherateofsamplesthatareprocessedonthecobas u701analyzer

Test parameters •Urinestripanalysis:ERY ErythrocytesandhemoglobinLEU LeukocytesNIT NitriteKET KetonesGLU GlucosePRO ProteinUBG UrobilinogenBIL BilirubinpHCOL ColorCLA ClaritySG Specificgravity

•Urinemicroscopyanalysis:RBC RedbloodcellsWBC WhitebloodcellsNEC Non-squamousepithelialcellsSEC SquamousepithelialcellsYEA YeastsCRY CrystalsBAC BacteriaHYA HyalinecastsSPRM SpermMUC MucusPAT Pathologicalcasts

Consumables cobas u pack:cassettewith400stripsforurinestripanalysiscobas u cuvette:cassettewith400cuvettesforurinemicroscopyanalysis

Sample input/output •Load/unloadcapacity:75samples(=15racks),continuousloading/unloading•Rack:5positionrack,RDstandardrack•Tray:traywith15racks/75samples,RDstandardtray•Automaticallystartsoperationafterrouting,priorityoremergencysamplesloading

Sample container types Length:65-115mm.Diameter:13-16mm.Bottom:round,conicalorfalse

Minimal sample volume •Teststripandmicroscopy:2.8mL•Teststrip:2.0mL•Microscopy:2.0mL

•Teststripreducedvolume(nomeasuringcellmeasurements):1.5mL

•Teststripreducedvolumeandmicroscopy:2.3mL

Measurement principles •Reflectancephotometry:with4differentwavelengths(465,528,560and615nm)•Refractometry:SGtesting•Turbimetry:claritytesting•Automatedmicroscopy•Automaticimageevaluation

Calibration •cobas ucalibrationstripforurinestripanalysis•Referencecuvetteforurinemicroscopyanalysis

Storage capacity •Testresults:upto10,000sampletestresults(includingimages)•QC,photometercalibration,measuringcellcalibrationandmicroscopecheck:upto300foreach•Operatorcanexportallresultsontheanalyzer,includingsedimentimages,QCandcalibrationresults

Electrical requirements •Linevoltage: 100-125VAC,permanentconnection(+10%,-15%) 200-240VAC,permanentconnection(+10%,-15%)•Linefrequency: 50or60Hz(±5%)

Regulatory requirements CE,us/cETL,CBTestCertificateThesystemiscompliantwiththefollowingstandards:• IEC61010-1:2001• IEC61010-2-101:2002• IEC61010-2-081:2001+A1:2003•UL61010-1•CAN/CSAC22.2No.61010-1-04+GI1•CAN/CSAC22.2No.61010-2-101:04•CAN/CSAC22.2No.61010-2-081-04(R09)

Operating conditions •Ambientroomtemperature18to32°C(64.4to90°F)•Relativehumidity30%-80%,noncondensing

Physical dimensions •cobas u601module:Width(withbuffers) 107.9cm(42.48in)Width(withoutbuffers) 68.7cm(27.05in)Depth 53.2cm(20.94in)Height 64.4cm(25.35in)

•cobas u701module:Width(withbuffers) 107.9cm(42.48in)Width(withoutbuffers) 68.7cm(27.05in)Depth 53.2cm(20.94in)Height 64.4cm(25.35in)

•Urineworkarea(withbuffers):Width 179cm(70.5in)Depth 53cm(21in)Height 64.4cm(25.4in)

Weight •cobas u601module:Weight(withbuffers) 169.3kg(373.2lb)Weight(withoutbuffers)157.1kg(346.3lb)

•cobas u701module:Weight(withbuffers) 88.8kg(195.8lb)Weight(withoutbuffers)76.6kg(168.9lb)

•Urineworkarea(withbuffers):Weight174kg(386lbs.)

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