年別 治療周期数

0

50,000

100,000

150,000

200,000

250,000

300,000

1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011

症例数

西暦

FET周期 ICSI周期 IVF周期

年別 出生児数

0

5,000

10,000

15,000

20,000

25,000

30,000

35,000

1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011

症例数

西暦

FET出生児 ICSI出生児 IVF出生児

年別 妊娠率・生産率

0%

5%

10%

15%

20%

25%

30%

35%

40%

1985 1986 1987 1988 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011

西暦

妊娠率（/ET、新鮮)

妊娠率（/ET、凍結)

生産率（/採卵）

IVF（GIFT,その他を含む） ICSI（SPLITを含む） 凍結融解胚

治療周期数 採卵周期数 妊娠周期数 出生児数 治療周期数 採卵周期数 妊娠周期数 出生児数 治療周期数 妊娠周期数 出生児数

1985 1,195 1,195 64

1986 752 752 56

1987 1,503 1,503 135

1988 1,702 1,702 257

1989 4,218 3,890 580 446 184 7 3

1990 7,405 6,892 1,178 1,031 160 17 17

1991 11,177 10,581 2,015 1,661 369 57 39

1992 17,404 16,381 2,702 2,525 963 936 42 35 553 79 66

1993 21,287 20,345 3,730 3,334 2,608 2,447 176 149 681 86 71

1994 25,157 24,033 4,069 3,734 5,510 5,339 759 698 1,303 179 144

1995 26,648 24,694 4,246 3,810 9,820 9,054 1,732 1,579 1,682 323 298

1996 27,338 26,385 4,818 4,436 13,438 13,044 2,799 2,588 2,900 449 386

1997 32,247 30,733 5,730 5,060 16,621 16,376 3,495 3,262 5,208 1,086 902

1998 34,929 33,670 6,255 5,851 18,657 18,266 3,952 3,701 8,132 1,748 1,567

1999 36,085 34,290 6,812 5,870 23,015 22,350 4,702 4,248 9,919 2,197 1,811

2000 31,334 29,907 6,328 5,447 26,712 25,794 5,240 4,582 11,644 2,658 2,243

2001 32,676 31,051 6,749 5,829 30,369 29,309 5,924 4,862 13,028 3,080 2,467

2002 34,953 33,849 7,767 6,443 34,824 33,823 6,775 5,486 15,874 4,091 3,298

2003 38,575 36,480 8,336 6,608 38,871 36,663 7,506 5,994 24,394 6,196 4,793

2004 41,619 39,656 8,542 6,709 44,698 43,628 7,768 5,921 30,193 7,595 5,529

2005 42,822 40,471 8,893 6,706 47,579 45,388 8,019 5,864 35,013 9,384 6,530

2006 44,778 42,248 8,509 6,256 52,539 49,854 7,904 5,401 42,146 11,797 7,929

2007 53,873 52,165 7,416 5,144 61,813 60,294 7,784 5,194 45,411 13,964 9,257

2008 59,148 57,217 6,897 4,664 71,350 69,864 7,017 4,615 60,026 18,590 12,422

2009 63,083 60,754 6,891 5,046 76,790 75,340 7,330 5,180 73,696 23,203 16,442

2010 67,714 64,966 6,556 4,657 90,677 88,822 7,699 5,277 83,626 37,364 19,001

2011 71,422 68,651 6,341 4,546 102,473 100,518 7,601 5,415 95,660 31,704 22,452

ART治療周期数 2011

0

5,000

10,000

15,000

20,000

25,000

周期数

年齢（歳）

総治療周期数 269,659

移植周期数 158,166

妊娠周期数 45,663

生産周期数 31,166

ART妊娠率・生産率・流産率 2011

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

0%

5%

10%

15%

20%

25%

30%

35%

40%

45%

50%

流産率

妊娠率・生産率

年齢（歳）

妊娠率/総治療

妊娠率/総ET

生産率/総治療

流産率/総妊娠

ART妊娠率・生産率・流産率 2011

0%

10%

20%

30%

40%

50%

60%

70%

妊娠率・生産率・流産率

年齢（歳）

妊娠/治療

妊娠/ET

生産/治療

流産/妊娠

2011年全て

年齢別総治療周期

数移植周期数 妊娠周期数 生産周期数 流産数

妊娠率/総治療

妊娠率/総ET

生産率/総治療

流産率/総妊娠

20以下 17 5 1 1 0 12.50% 20.00% 12.50%

21 11 7 5 2 2 45.45% 71.43% 18.18% 40.00%

22 57 35 14 9 4 24.56% 40.00% 15.79% 28.57%

23 138 92 43 31 11 31.16% 46.74% 22.46% 25.58%

24 308 185 70 55 9 22.73% 37.84% 17.86% 12.86%

25 685 455 177 132 32 25.84% 38.90% 19.27% 18.08%

26 1,086 722 297 237 42 27.35% 41.14% 21.82% 14.14%

27 1,971 1,362 561 429 91 28.46% 41.19% 21.77% 16.22%

28 3,074 2,098 858 661 146 27.91% 40.90% 21.50% 17.02%

29 4,671 3,189 1,244 949 226 26.63% 39.01% 20.32% 18.17%

30 6,233 4,268 1,661 1,269 290 26.65% 38.92% 20.36% 17.46%

31 8,304 5,655 2,184 1,650 397 26.30% 38.62% 19.87% 18.18%

32 10,667 7,320 2,782 2,078 544 26.08% 38.01% 19.48% 19.55%

33 12,956 8,834 3,272 2,432 622 25.25% 37.04% 18.77% 19.01%

34 15,316 10,372 3,736 2,769 740 24.39% 36.02% 18.08% 19.81%

35 17,399 11,711 4,275 3,084 920 24.57% 36.50% 17.73% 21.52%

36 19,007 12,451 4,243 3,059 920 22.32% 34.08% 16.09% 21.68%

37 20,783 13,343 4,305 3,002 1049 20.71% 32.26% 14.44% 24.37%

38 21,764 13,660 4,128 2,785 1094 18.97% 30.22% 12.80% 26.50%

39 22,859 13,883 3,709 2,329 1170 16.23% 26.72% 10.19% 31.54%

40 22,122 12,584 2,981 1,784 1030 13.48% 23.69% 8.06% 34.55%

41 20,346 10,777 2,131 1143 862 10.47% 19.77% 5.62% 40.45%

42 18,378 9,088 1,452 688 684 7.90% 15.98% 3.74% 47.11%

43 15,598 7,052 900 361 489 5.77% 12.76% 2.31% 54.33%

44 11,267 4,483 412 153 241 3.66% 9.19% 1.36% 58.50%

45 6,518 2,236 148 53 88 2.27% 6.62% 0.81% 59.46%

46 3,963 1,166 50 15 34 1.26% 4.29% 0.38% 68.00%

47 2,228 640 16 3 11 0.72% 2.50% 0.13% 68.75%

48 992 248 6 3 2 0.60% 2.42% 0.30%

49 553 143 0 0 0 0.00% 0.00% 0.00%

50以上 388 102 2 0 2 0.52% 1.96% 0.00%

合計 269,659 158,166 45,663 31,166 11,752 16.93% 28.87% 11.56% 25.74%

ART妊娠率・生産率（新鮮胚移植） 2011

0.0%

5.0%

10.0%

15.0%

20.0%

25.0%

30.0%

35.0%

40.0%

45.0%

50.0%

年齢（歳）

周期あたり妊娠率

移植あたり妊娠率

周期あたり出産率

ART妊娠率・生産率（凍結胚移植） 2011

0.0%

5.0%

10.0%

15.0%

20.0%

25.0%

30.0%

35.0%

40.0%

45.0%

50.0%

年齢（歳）

周期あたり妊娠率

移植あたり妊娠率

周期あたり出産率

2011年 新鮮胚 2011年 凍結胚

新鮮総治療周期数

移植周期数

妊娠周期数

生産周期数

流産数妊娠率/総治療

妊娠率/総ET

生産率/総治療

流産率/総妊娠

凍結総治療周期数

移植周期数

妊娠周期数

生産周期数

流産数妊娠率/総治療

妊娠率/総ET

生産率/総治療

流産率/総妊娠

20歳以下 15 3 0 0 0 0.0% 0.0% 0.0% 20歳以下 2 2 1 1 0 50.0% 50.0% 50.0% 0.0%

21 10 6 4 2 1 40.0% 66.7% 20.0% 21 1 1 1 0 1 100.0% 100.0% 0.0% 100.0%

22 40 18 7 4 2 17.5% 38.9% 10.0% 28.6% 22 17 17 7 5 2 41.2% 41.2% 29.4% 28.6%

23 84 38 18 13 4 21.4% 47.4% 15.5% 22.2% 23 54 54 25 18 7 46.3% 46.3% 33.3% 28.0%

24 179 59 16 15 0 8.9% 27.1% 8.4% 0.0% 24 129 126 54 40 9 41.9% 42.9% 31.0% 16.7%

25 385 164 49 41 5 12.7% 29.9% 10.6% 10.2% 25 298 289 127 90 27 42.6% 43.9% 30.2% 21.3%

26 602 257 92 75 10 15.3% 35.8% 12.5% 10.9% 26 483 465 205 162 32 42.4% 44.1% 33.5% 15.6%

27 1088 498 174 140 21 16.0% 34.9% 12.9% 12.1% 27 882 863 386 289 70 43.8% 44.7% 32.8% 18.1%

28 1664 734 269 206 46 16.2% 36.6% 12.4% 17.1% 28 1406 1360 588 454 100 41.8% 43.2% 32.3% 17.0%

29 2597 1175 349 269 67 13.4% 29.7% 10.4% 19.2% 29 2072 2013 895 680 159 43.2% 44.5% 32.8% 17.8%

30 3453 1561 493 397 70 14.3% 31.6% 11.5% 14.2% 30 2779 2707 1168 872 220 42.0% 43.1% 31.4% 18.8%

31 4590 2026 642 501 96 14.0% 31.7% 10.9% 15.0% 31 3709 3626 1542 1149 301 41.6% 42.5% 31.0% 19.5%

32 5951 2740 867 665 150 14.6% 31.6% 11.2% 17.3% 32 4705 4573 1915 1413 394 40.7% 41.9% 30.0% 20.6%

33 7211 3258 959 731 169 13.3% 29.4% 10.1% 17.6% 33 5741 5575 2312 1700 453 40.3% 41.5% 29.6% 19.6%

34 8680 3893 1147 871 206 13.2% 29.5% 10.0% 18.0% 34 6627 6472 2585 1896 533 39.0% 39.9% 28.6% 20.6%

35 10033 4537 1349 1012 254 13.4% 29.7% 10.1% 18.8% 35 7356 7167 2922 2068 666 39.7% 40.8% 28.1% 22.8%

36 11067 4763 1240 879 279 11.2% 26.0% 7.9% 22.5% 36 7934 7685 3001 2178 641 37.8% 39.1% 27.5% 21.4%

37 12573 5350 1341 947 322 10.7% 25.1% 7.5% 24.0% 37 8206 7991 2963 2055 727 36.1% 37.1% 25.0% 24.5%

38 13532 5677 1251 822 343 9.2% 22.0% 6.1% 27.4% 38 8222 7978 2876 1962 751 35.0% 36.0% 23.9% 26.1%

39 14654 5945 1169 749 369 8.0% 19.7% 5.1% 31.6% 39 8200 7935 2539 1579 801 31.0% 32.0% 19.3% 31.5%

40 14775 5500 931 544 323 6.3% 16.9% 3.7% 34.7% 40 7346 7083 2050 1240 707 27.9% 28.9% 16.9% 34.5%

41 14284 4921 686 345 302 4.8% 13.9% 2.4% 44.0% 41 6056 5852 1445 798 560 23.9% 24.7% 13.2% 38.8%

42 13404 4302 451 193 236 3.4% 10.5% 1.4% 52.3% 42 4967 4782 1001 495 448 20.2% 20.9% 10.0% 44.8%

43 11753 3352 256 101 140 2.2% 7.6% 0.9% 54.7% 43 3842 3696 644 260 349 16.8% 17.4% 6.8% 54.2%

44 8901 2210 112 31 74 1.3% 5.1% 0.3% 66.1% 44 2363 2272 300 122 167 12.7% 13.2% 5.2% 55.7%

45 5364 1141 48 15 28 0.9% 4.2% 0.3% 58.3% 45 1151 1093 100 38 60 8.7% 9.1% 3.3% 60.0%

46 3402 638 15 3 12 0.4% 2.4% 0.1% 80.0% 46 559 527 35 12 22 6.3% 6.6% 2.1% 62.9%

47 1921 358 5 1 3 0.3% 1.4% 0.1% 60.0% 47 307 282 11 2 8 3.6% 3.9% 0.7% 72.7%

48 867 134 2 1 1 0.2% 1.5% 0.1% 50.0% 48 124 114 4 2 1 3.2% 3.5% 1.6% 25.0%

49 482 76 0 0 0 0.0% 0.0% 0.0% 49 70 67 0 0 0 0.0% 0.0% 0.0%

50歳以上 334 48 0 0 0 0.0% 0.0% 0.0% 50歳以上 52 52 2 0 2 3.8% 3.8% 0.0% 100.0%

合計 173895 65382 13942 9573 3533 8.0% 21.3% 5.5% 25.3% 合計 95660 92719 31704 21580 8218 33.1% 34.2% 22.6% 25.9%

妊娠率（移植胚数・ステージ別） 2011

新鮮胚 凍結胚

0%

5%

10%

15%

20%

25%

30%

35%

40%

45%

50%

252627282930313233343536373839404142434445464748

妊娠率

年齢（歳）

新鮮初期胚SET

新鮮初期胚DET

新鮮胚盤胞SET

新鮮胚盤胞DET

0%

5%

10%

15%

20%

25%

30%

35%

40%

45%

50%

252627282930313233343536373839404142434445464748

妊娠率

年齢（歳）

凍結初期胚

SET

凍結初期胚

DET

凍結胚盤胞

SET

凍結胚盤胞

DET

移植胚ステージ・移植胚数別

妊娠率 多胎率新鮮初期胚 SET

新鮮初期胚 DET

新鮮胚盤胞 SET

新鮮胚盤胞 DET

凍結初期胚 SET

凍結初期胚 DET

凍結胚盤胞 SET

凍結胚盤胞 DET

新鮮初期胚 SET

新鮮初期胚 DET

新鮮胚盤胞 SET

新鮮胚盤胞 DET

凍結初期胚 SET

凍結初期胚 DET

凍結胚盤胞 SET

凍結胚盤胞 DET

20以下 0% 0% 100% 0% 0%

21 50% 100% 67% 100% 0% 0% 0% 0%

22 23% 100% 75% 50% 36% 0% 0% 0% 0% 0%

23 30% 33% 71% 100% 36% 0% 50% 67% 0% 0% 0% 0% 0% 0% 50%

24 21% 20% 37% 50% 22% 29% 52% 44% 0% 0% 0% 0% 0% 0% 0% 43%

25 23% 22% 48% 25% 28% 20% 52% 28% 0% 25% 0% 0% 0% 50% 1% 0%

26 36% 29% 42% 0% 26% 27% 52% 48% 0% 25% 0% 4% 20% 1% 21%

27 30% 30% 42% 75% 32% 43% 49% 41% 0% 24% 0% 33% 5% 42% 1% 11%

28 36% 30% 41% 44% 27% 29% 50% 38% 1% 29% 0% 17% 0% 42% 1% 38%

29 28% 20% 37% 33% 30% 20% 50% 49% 1% 18% 0% 25% 2% 13% 2% 21%

30 29% 23% 39% 47% 25% 32% 49% 46% 1% 21% 2% 25% 0% 14% 1% 27%

31 29% 26% 39% 38% 30% 28% 47% 43% 0% 19% 1% 22% 3% 22% 1% 26%

32 30% 24% 40% 34% 29% 28% 47% 43% 0% 16% 0% 24% 1% 24% 1% 24%

33 26% 30% 35% 38% 27% 26% 47% 42% 0% 15% 2% 26% 0% 18% 1% 24%

34 28% 28% 36% 31% 26% 31% 45% 42% 0% 18% 1% 15% 1% 13% 1% 23%

35 29% 26% 35% 34% 26% 26% 46% 44% 1% 19% 1% 16% 0% 19% 1% 22%

36 24% 26% 32% 33% 24% 29% 44% 42% 0% 16% 1% 22% 1% 18% 2% 19%

37 22% 25% 30% 32% 22% 27% 42% 40% 1% 15% 1% 15% 0% 17% 1% 18%

38 19% 22% 29% 26% 22% 23% 40% 42% 1% 10% 1% 14% 1% 14% 1% 18%

39 16% 20% 28% 28% 19% 21% 37% 35% 0% 11% 0% 16% 2% 11% 1% 15%

40 14% 19% 22% 20% 15% 22% 33% 34% 0% 10% 0% 11% 0% 12% 1% 13%

41 11% 15% 20% 18% 12% 18% 29% 27% 0% 6% 0% 7% 2% 8% 1% 11%

42 8% 12% 14% 16% 11% 11% 26% 23% 0% 8% 1% 14% 0% 8% 1% 14%

43 6% 10% 10% 12% 6% 10% 23% 21% 1% 1% 0% 6% 0% 5% 0% 11%

44 4% 6% 8% 13% 8% 7% 17% 15% 0% 0% 5% 0% 0% 8% 1% 4%

45 3% 6% 9% 10% 2% 5% 14% 13% 0% 0% 0% 0% 0% 0% 0% 0%

46 1% 3% 10% 0% 3% 7% 8% 7% 0% 0% 0% 0% 0% 5% 0%

47 0% 3% 10% 0% 1% 4% 7% 10% 0% 0% 0% 0% 0% 0%

48 1% 0% 25% 0% 0% 0% 8% 0% 0% 0% 0%

49 0% 0% 0% 0% 0% 0% 0% 0%

50歳以上 0% 0% 0% 0% 0% 22% 0%

合計 19% 19% 29% 26% 20% 21% 40% 37% 0% 13% 1% 16% 1% 15% 1% 19%

SET実施率 5年間の比較（新鮮胚移植）

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

単胚移植率

年齢（歳）

2007新鮮SET率

2008新鮮SET率

2009新鮮SET率

2010新鮮SET率

2011新鮮SET率

SET実施率 5年間の比較（凍結胚移植）

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

単胚移植率

年齢（歳）

2007凍結SET率

2008凍結SET率

2009凍結SET率

2010凍結SET率

2011凍結SET率

刺激方法別 内訳 2007-2011

刺激周期 妊娠周期

自然

10%

CC18%

CC+FSH19%

FSH3%

GnRH agonist32%

GnRH antago18%

自然

5% CC8%

CC+FSH12%

FSH3%

GnRH agonist51%

GnRH antago21%

刺激方法別 年齢別 治療あたり妊娠率 2007-2011

26-29

35-39

0.0%

5.0%

10.0%

15.0%

20.0%

25.0%

30.0%

35.0%

40.0%

自然CC

CC+FSHFSH

agonistantago

刺激方法別 年齢別 移植あたり妊娠率 2007-2011

26-29

35-39

0.0%

5.0%

10.0%

15.0%

20.0%

25.0%

30.0%

35.0%

40.0%

自然CC

CC+FSHFSH

agonistantago

受精卵を得た新鮮周期の経過 2011

移植中止17%

全胚凍結35%

胚移植

（凍結余

剰胚あり）18%

胚移植

（余剰胚

なし）30%

受精卵を得た採卵周期数 134,532周期

移植中止周期 22,966

移植可能胚を得た周期 111,563

全胚凍結を行った周期 46,492

新鮮胚移植（凍結余剰胚あり） 24,846

新鮮胚移植（余剰胚なし） 40,225