COLLABORATIVE SERVICES We pride ourselves on going above and beyond to partner with our clients. Our services include:

IMPLEMENTATION The Pre-installation Process begins with a site review, factory acceptance testing and optional certified technician training. The Onsite Installation includes site acceptance testing and end user training. Industry-leading service programs are available following a 12-month comprehensive warranty.

SCIENTIFIC SUPPORT Our expert scientific team can assist with the development and optimization of new or existing assays to ensure your lab produces reliable data and runs at maximum efficiency.

INSTRUMENT AND SOFTWARE OPTIMIZATION Highly specific laboratory processes and protocols may require instrument and/or software modifications. The Douglas Scientific team is skilled at delivering optimized solutions to meet your needs.

CUSTOM AUTOMATION SERVICE Name the high-throughput application, and we’ll put the power of Douglas Scientific innovation to work for you. The team at Douglas Scientific delivers extensive experience in motion and movement, automated processing, and high-throughput scientific applications such as:

• Sample Purification/Extraction • Liquid Handling • Miniaturized Reactions • Incubation • Thermal Cycling • Detection • High Capacity PCR • Customized Compound Embedding in Array Tape• And more!

This experience, coupled with our rapid development capabilities provides customers with a truly responsive development partner.

ABOUT DOUGLAS SCIENTIFIC Douglas Scientific LLC, is a rapidly growing laboratory automation company located in Alexandria, MN, with a team of over 100 professionals bringing together expertise in engineering, biosciences, automation, motion control and other fields. At the core of Douglas Scientific is a dedication to making the world a better place by delivering innovative laboratory automation solutions.

Douglas Scientific designs and manufactures a full line of laboratory instrumentation—Nexar® and IntelliQube® systems—to enable PCR reactions in Array Tape.

As a leading automation company delivering on its mission, Douglas Scientific has enabled laboratories around the world to leverage the patented Array Tape consumable. This innovative microplate replacement consists of a continuous polymer strip embossed with microliter wells that can be used in a variety of laboratory applications. As a result, scientists worldwide have processed billions of samples in the areas of plant genomics, animal health, clinical diagnostics and pharmaceuticals at unprecedented speed and fractional costs. By partnering with the most creative and dedicated scientists around the world, our company continues to deliver advancements to address several imminent global issues and challenges.

3600 Minnesota Street, Alexandria, MN 56308 Tel: 320.762.6888 Fax: 320.762.6259

www.DouglasScientific.com

Partnering with you to make the world a better place

Array Tape®

platform

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ARAYA® The Araya is a fluorescent detection instrument designed for automated scanning in Array Tape. The system is available as a stand alone instrument or an inline module for the Nexar.

ARRAY TAPE® CONSUMABLE Array Tape is a continuous polymer strip, serially embossed with reaction wells in 96- and 384-well arrays. A 768-well array format is available for the IntelliQube. Array Tape is also available in custom array formats, well geometries, well volumes and reel lengths.

INTELLICS® SOFTWARE Innovative software provides centralized data management, instrument monitoring, intelligent run optimization, protocol generation and streamlined data analysis.

INTELLIQUBE® The IntelliQube is the next evolution of the Array Tape Platform and is designed for medium-to high-throughput processing. The system combines: sample and reagent dispensing, sealing, thermal cycling, and data analysis into a single, compact instrument. IntelliQube supports quantitative real-time PCR, end-point PCR and isothermal chemistries, allowing you to realize the benefits of inline automation enabled by the innovative Array Tape consumable.

Paradigm changing high-throughput solutions

www.DouglasScientific.com

“The Array Tape Platform was our choice for a HTP solution based on throughput potential as well as the immediate cost-savings associated with the walk-away automation of platform instrumentation and the miniaturized reaction volumes in Array Tape.”

Edwin van Zon, Technical Analyst of Biology for Rijk Zwaan

MARKETS• Agbiotechnology• Animal Health• Pharmaceuticals• Horticulture• Food Safety • Clinical Diagnostics• Research

The products of Douglas Scientific LLC are not FDA-approved for use in human diagnostic procedures.

The Array Tape® Platform provides quality data and repeatable results with flexible, high-throughput systems at a lower cost per data point. Douglas Scientific instruments are optimized for use with our revolutionary consumable, Array Tape. This flexible microplate replacement enables inline and integrated automation of an entire laboratory process. These automated and robust systems allow scientists to focus on the data, not the automation.

RETURN ON INVESTMENT Clients can realize a return on investment in as little as three to six months.

SAVE UP TO 90% ON REAGENTS Reaction volumes in Array Tape are typically 10-32% of those in microplates.

OFFSET LABOR COSTS BY 60% OR MORE Streamline your processes, eliminate bottlenecks and make the most efficient use of your lab personnel. The inline nature of the Array Tape platform significantly reduces the need for manual handling and robotics.

APPLICATIONS Current applications supported include:• End-Point PCR • qPCR • End-Point Isothermal DNA Amplification

PRODUCTS

NEXAR® The Nexar, our ultra high-throughput solution, is an inline liquid handling system for sample and reagent processing in Array Tape. The instrument provides dispensing, sealing, source plate storage and optional processes such as incubation, thermal cycling and dehydration. Flexible module configurations enable processing for a variety of applications.

SOELLEX® The Soellex is a high-throughput, PCR thermal cycler, 3-chamber water bath capable of simultaneously processing up to three spools (230,400 reaction wells) of Array Tape or 152 microplates (384-well) in a single process run.

For details on this analysis, please visit our website.

Araya® Soellex® Nexar®

Establish the most efficient lab!The inline automation of the Array Tape Platform enables you to increase throughput by 2-10X.

Instrument Application Plate equivalents Data points per 8-hour day

IntelliQube qPCR 12 4,608

IntelliQube End-Point PCR 60 23,040

Nexar End-Point PCR 400 153,600

For details on this analysis, please visit our website.

Throughput is highly dependent on specific cycling conditions and chemistry selection. These estimates assume the standard TaqMan SNP Genotyping assay protocol.

IntelliQube

ARAYA® The Araya is a fluorescent detection instrument designed for automated scanning in Array Tape. The system is available as a stand alone instrument or an inline module for the Nexar.

ARRAY TAPE® CONSUMABLE Array Tape is a continuous polymer strip, serially embossed with reaction wells in 96- and 384-well arrays. A 768-well array format is available for the IntelliQube. Array Tape is also available in custom array formats, well geometries, well volumes and reel lengths.

INTELLICS® SOFTWARE Innovative software provides centralized data management, instrument monitoring, intelligent run optimization, protocol generation and streamlined data analysis.

INTELLIQUBE® The IntelliQube is the next evolution of the Array Tape Platform and is designed for medium-to high-throughput processing. The system combines: sample and reagent dispensing, sealing, thermal cycling, and data analysis into a single, compact instrument. IntelliQube supports quantitative real-time PCR, end-point PCR and isothermal chemistries, allowing you to realize the benefits of inline automation enabled by the innovative Array Tape consumable.

Paradigm changing high-throughput solutions

www.DouglasScientific.com

“The Array Tape Platform was our choice for a HTP solution based on throughput potential as well as the immediate cost-savings associated with the walk-away automation of platform instrumentation and the miniaturized reaction volumes in Array Tape.”

Edwin van Zon, Technical Analyst of Biology for Rijk Zwaan

MARKETS• Agbiotechnology• Animal Health• Pharmaceuticals• Horticulture• Food Safety • Clinical Diagnostics• Research

The products of Douglas Scientific LLC are not FDA-approved for use in human diagnostic procedures.

The Array Tape® Platform provides quality data and repeatable results with flexible, high-throughput systems at a lower cost per data point. Douglas Scientific instruments are optimized for use with our revolutionary consumable, Array Tape. This flexible microplate replacement enables inline and integrated automation of an entire laboratory process. These automated and robust systems allow scientists to focus on the data, not the automation.

RETURN ON INVESTMENT Clients can realize a return on investment in as little as three to six months.

SAVE UP TO 90% ON REAGENTS Reaction volumes in Array Tape are typically 10-32% of those in microplates.

OFFSET LABOR COSTS BY 60% OR MORE Streamline your processes, eliminate bottlenecks and make the most efficient use of your lab personnel. The inline nature of the Array Tape platform significantly reduces the need for manual handling and robotics.

APPLICATIONS Current applications supported include:• End-Point PCR • qPCR • End-Point Isothermal DNA Amplification

PRODUCTS

NEXAR® The Nexar, our ultra high-throughput solution, is an inline liquid handling system for sample and reagent processing in Array Tape. The instrument provides dispensing, sealing, source plate storage and optional processes such as incubation, thermal cycling and dehydration. Flexible module configurations enable processing for a variety of applications.

SOELLEX® The Soellex is a high-throughput, PCR thermal cycler, 3-chamber water bath capable of simultaneously processing up to three spools (230,400 reaction wells) of Array Tape or 152 microplates (384-well) in a single process run.

For details on this analysis, please visit our website.

Araya® Soellex® Nexar®

Establish the most efficient lab!The inline automation of the Array Tape Platform enables you to increase throughput by 2-10X.

Instrument Application Plate equivalents Data points per 8-hour day

IntelliQube qPCR 12 4,608

IntelliQube End-Point PCR 60 23,040

Nexar End-Point PCR 400 153,600

For details on this analysis, please visit our website.

Throughput is highly dependent on specific cycling conditions and chemistry selection. These estimates assume the standard TaqMan SNP Genotyping assay protocol.

IntelliQube

COLLABORATIVE SERVICES We pride ourselves on going above and beyond to partner with our clients. Our services include:

IMPLEMENTATION The Pre-installation Process begins with a site review, factory acceptance testing and optional certified technician training. The Onsite Installation includes site acceptance testing and end user training. Industry-leading service programs are available following a 12-month comprehensive warranty.

SCIENTIFIC SUPPORT Our expert scientific team can assist with the development and optimization of new or existing assays to ensure your lab produces reliable data and runs at maximum efficiency.

INSTRUMENT AND SOFTWARE OPTIMIZATION Highly specific laboratory processes and protocols may require instrument and/or software modifications. The Douglas Scientific team is skilled at delivering optimized solutions to meet your needs.

CUSTOM AUTOMATION SERVICE Name the high-throughput application, and we’ll put the power of Douglas Scientific innovation to work for you. The team at Douglas Scientific delivers extensive experience in motion and movement, automated processing, and high-throughput scientific applications such as:

• Sample Purification/Extraction • Liquid Handling • Miniaturized Reactions • Incubation • Thermal Cycling • Detection • High Capacity PCR • Customized Compound Embedding in Array Tape• And more!

This experience, coupled with our rapid development capabilities provides customers with a truly responsive development partner.

ABOUT DOUGLAS SCIENTIFIC Douglas Scientific LLC, is a rapidly growing laboratory automation company located in Alexandria, MN, with a team of over 100 professionals bringing together expertise in engineering, biosciences, automation, motion control and other fields. At the core of Douglas Scientific is a dedication to making the world a better place by delivering innovative laboratory automation solutions.

Douglas Scientific designs and manufactures a full line of laboratory instrumentation—Nexar® and IntelliQube® systems—to enable PCR reactions in Array Tape.

As a leading automation company delivering on its mission, Douglas Scientific has enabled laboratories around the world to leverage the patented Array Tape consumable. This innovative microplate replacement consists of a continuous polymer strip embossed with microliter wells that can be used in a variety of laboratory applications. As a result, scientists worldwide have processed billions of samples in the areas of plant genomics, animal health, clinical diagnostics and pharmaceuticals at unprecedented speed and fractional costs. By partnering with the most creative and dedicated scientists around the world, our company continues to deliver advancements to address several imminent global issues and challenges.

3600 Minnesota Street, Alexandria, MN 56308 Tel: 320.762.6888 Fax: 320.762.6259

www.DouglasScientific.com

Partnering with you to make the world a better place

Array Tape®

platform

2/15