CONFIDENTIAL

ChangingEnvironment

ChangingEnvironment

“Should”“Should”

(What Might Be)(What Might Be)

Mid-term PlanProduct Roadmap

Mid-term PlanProduct Roadmap

Long-term PlanLong-term Plan

Last Year’sDASH

ManagementResults

Last Year’sDASH

ManagementResults

DASHProcessDASH

Process

ReflectionReflectionFocus

on

VitalFew

Focuson

VitalFew

DASH MITsDASH MITs

(Key Drivers)(Fact) (Vision)

Past Future

(Given)

(What Is)

Business Planning Process

CONFIDENTIAL

NIST TASKS YR1 and YR2

2008

2009

CONFIDENTIAL

Financial Awarded $2M NIST Grant Set-up accounts and banking – first funds withdrawn Negotiating with a potential investor in Italy Financial system validated

Organization 1 PT employee & 2 consultants hired Held a Kick-Off meeting Successful meeting with NIST LLC formed – all assets transferred Added CTRC (Niko Papanikolau) to our advisory board

R&D Solid Works installed – first pass model completed First pass testing fixture designed Initial material test parameters defined

Partners Met with Siemens and invited to visit factory to move ahead In discussion with Vermont Composites for table top design/manufacturing Radionics interested in supplying the mMLC – will provide a dummy unit when needed

Accomplishments Q4-2007

CONFIDENTIAL

Financial Additional investment not secured Missed out on a grant opportunity with Montefiore (SGK)

Organization

R&D Monte Carlo engine not defined Initial pass Monte Carlo not completed

Partners Varian not interested in collaboration

Short-Falls Q4-2007

CONFIDENTIAL

Vital Few Q4-07

ITEM (ATP RELATED) RESPONSIBLE % COMPLETED

Generate first system specificationsOverall configurationFunctional specificationIdentify applicable standards and regulations

AS/JK

75

75

100

Set-up Monte Carlo and obtain first resultsIdentify MC model to use

Model basic shielding properties

KH/AS

25

15

Design first shielding experimentMechanical design and materials identified

Equipment specified and test plan written

MD/JK

90

90

Generate first pass mechanical designDesign first full-scale model

PS/AS/JK

90

CONFIDENTIAL

PS MITs Q4,07

TASKS Due Date Progress

Model a linac in SWMeasure linac

Model in SW

Integrate with machine

12/5

12/15

12/30

Done

Done

Done

Update machine model in SWDesign MLC

Design beam-stop

Add human to model (male added)

12/15

12/20

12/20

Done

Done

Done

Human factorFirst pass ideal dimension for table top design 12/30 50%

CONFIDENTIAL

Q1-2008

CONFIDENTIAL

Vital Few Q1-08ITEM RESPONSIBLE COMPL. DATE % COMPLETED

Generate first system specificationsOverall configurationFunctional specificationIdentify applicable standards

AS

JK

AS/JK

3/1

3/1

1/15

20

10

100

MC ResultsSelect and install another MC engine (GEANT, MCNP?)

Initial test shielding fixture

Determine machine scatter for geometry

AS

KH

KH

1/31

1/31

3/30

100

10

Build first physical model of the MammoKnifeFine-tune SolidWorks modelOrder building materialsBuild model

PSASAS/PS

1/191/152/1

30100

Complete design of shielding experimentRun Monte Carlo to validate designOrder equipment and components to build the testing fixtureComplete build of testing fixture & equipment preparation

KH

AS/PS

AS/MD

2/29

3/1

3/30

ClearView ProjectFirst design to Vermont for estimate

Check EU standards for testing

PS

JK

2/29

2/15

10

Move ahead with Patent issuesVisit patent office

Submit new claims

AS

AS

1/24

2/15

Seek fundingShort list 5 VC firms

Submit business plan

Present to at least 2 VCs

JK

JK

JK

2/15

2/28

3/15

CONFIDENTIAL

Vital Few Q1-08

ITEM RESPONSIBLE COMPL. DATE % COMPLETED

Generate first system specificationsComplete overall configurationComplete functional specification

AS/JK

JK

3/1

3/1

MC ResultsSelect and install another MC engine (GEANT, MCNP?)

Initial test shielding fixture

Determine machine scatter for geometry

AS

JK/KH

JK/KH

1/31

1/31

3/30

Build first physical model of the MammoKnifeFine-tune SolidWorks modelOrder building materialsBuild model

PSASAS/PS

1/191/152/1

Complete design of shielding experimentRun Monte Carlo to validate designOrder equipment and components to build the testing fixtureComplete build of testing fixture & equipment preparation

KH

AS/PS

AS/MD

2/29

3/1

3/30

CONFIDENTIAL

PS MITs Q1-08

TASKS Due Date Progress

CONFIDENTIAL

MD MITs Q1-08

TASKS Due Date Progress

CONFIDENTIAL

KH MITs Q1-08

TASKS Due Date Progress