The Integrated Lab

ConnectedWelcome to the fully integrated autoimmune laboratory.

• Savestimebyreducinghands-onfunctions

• Reducescostswithautomationefficiencies

• Maximizesworkflowwithdata-drivenintegration

• Createsatranscriptionfree,paperlessenvironment

• Optimizesqualitycontrolwithcentralizedanalysis

NOVA Lite® Barcoded IFA Slides

NOVA View®

BIO-FLASH®

QUANTA Link®

QUANTA-Lyser®

ProcessingThe Integrated Lab DataDrivenWorkflowandCostEfficiency

WhatistheIntegratedLab?AcompleteportfolioofInovainstrumentsseamlesslyconnectedbyacentraldata managementsystemthatefficientlyintegratestheautoimmunelaboratory’sfunctional testingareastoincreaseproductivity,improvesampleintegrity,optimizequalitycontrol andgenerateoverallcostreductions.

NOVA Lite® IFA SlidesContainsmartbarcodesthat connectpatientsamplestoa welllocation.

NOVA View®*Anautomatedmicroscopethatanalyseseachwellandcreatesadigitalimage fortechnicalreview.

BIO-FLASH®Fully automated randomaccess chemiluminescent benchtopanalyzer for autoimmunity.

QUANTA Link®SeamlesslyintegratesinstrumentswithyourLIStoefficientlymanageworkflowandqualitycontrol.

QUANTA-Lyser®AnautomatedEIA/IFAslide processorcapableofreading IFAslidebarcodes.

*NOVAViewpendingFDAclearance

Processing InovaDiagnostics®

Efficient WorkflowAn integrated data management environmentforbetterthroughput

Quality Control OptimizedQCwithreal-time trendingandanalysis

Positive Patient IDBarcodedslidesandcentralizeddatainputimprovessampletraceability

Error-free Transcription Eliminatestranscriptionerrorsinsampleprocessingandanalysis

Increased ProductivityReducedhands-ontimeimprovesthroughput

Seamless IntegrationEfficientlyintegratesintoany LISforimmediatecontrol

ConsiderationsforIntegration

Laboratoryworkflowcomparison

The traditional labFunctionalareasoperateindependently,

withouttheabilitytoeasilyexchangedata.

The Inova Integrated LabImprovedproductivityinadatadrivenenvironment withvolumematchedtoinstrumentconfigurations

thatgenerateautomationefficiencies

Independentinstrumentconfiguration

Autoimmune EIA Assays

IFAAssays

AutoimmuneChemiluminescent

Assays

EsotericEIA

Inovainstrumentconfigurationwith QUANTALinkdatamanagement

Autoimmune EIA Assays

IFAAssays

AutoimmuneChemiluminescent

Assays

EsotericEIA

Inova Integrated Lab

IntegratedProcessing AutomatedEIA/IFAAnalyzerPlatform

QUANTA-Lyser® 160/240• Holdsupto6EIAplatesor30IFAslides• 4independentceramiccoatedpipettetips• QUANTA-Lyser160holdsupto160samplesperrun,andisconfiguredto maximizethenumberofanalytesperrun.

• QUANTA-Lyser240holdsupto240samplesperrun,andisconfiguredto optimizesamplethroughout

QUANTA-Lyser®

Flexibility and efficiency

TheQUANTA-Lyserfamilyofinstrumentsisthemostflexibleandefficientplatformfor EIAandIFAprocessing,withthreedifferentmodelstomeetthevolumerequirements of any laboratory.

QUANTA-Lyserisawalk-awayautomatedsystemthatcommunicateseffortlesslywith QUANTALink®toimproveworkflowefficienciesandqualitycontrol.

Rapid Processing SpeedIncreasesthroughput—independentfourprobe systemprovidesfastsample/reagentprocessing

Reduces CostWashableceramicpipetteseliminatedisposabletipsandreducewaste

Assay IntegrityConfirmsthatthesampleworklistand substratearematchedcorrectlyforIFA

Screen Alert Anon-screenalertinformstheoperatoriftheslide substratedoesnotmatchtheworklistorifaslidebarcode isscannedtwice

IntegratedProcessing AutomatedEIA/IFAAnalyzerPlatform

QUANTA-Lyser®

QUANTA-Lyser® 2 Compact and flexible

• Holdsupto2EIAplatesor15IFAslides• Holdsupto96samplesperrun• Oneceramiccoatedpipettetip• Idealplatformforesotericassaysorin settingsthatrequiremaximumflexibility andefficiency

Washable ceramic coated pipette tips reduce cost

IntegratedAnalysis AutomatedAnalysiswithPositivePatientID

NOVA View®

Digital IFA

AnewparadigminIFAanalysisandautomationusingdigitaltechnologyandproprietary algorithmstocapturelightintensityandcreatedigitalimagesforreview.

CoupledwithQUANTALink®datamanagementandNOVALite®barcodedslides, NOVAViewincreasesproductivitywhilehelpingprovidemoreconsistentresults.

NOVA Lite® IFA Barcoded SlidesBarcodedslidesenableseamlesslaboratory workflowbytracking patientdatafromsamplepreparationtoresult.

Showsmitoticimages

IntegratedAnalysis AutomatedAnalysiswithPositivePatientID

NOVAView®

NOVAViewanalysisandpatternrecognitionalgorithms

CentromereHomogeneousSpeckledPattern

Nucleolar and Nuclear Dot patterns not shown

Actual NOVA View images

Algorithm Analysis NOVAViewpattern recognitionalgorithms areanalogoustoa3-D holographicpicture.Thealgorithmdirectlymeasuresthepeaksandvalleysof eachimageandproposes apatternforconfirmation bytheoperator.

DAPI FITC FITC/DAPIOverlay

Prompts Analysis Samplescanbearrangedby positiveornegativeintensityfor easierreview

Reduces Hands-on TimeFullyautomatedslidereviewand imageacquisition

Positive Patient IDIsensuredbyscanningtheIFAslidebarcode,anddataisentereddirectlyintothescreenfortransfertotheLIS

Increases ProductivityImagereviewandreportingcanbescheduledanytimeafteranalysis

Supports StandardizationQuantitativealgorithmsfacilitateanalysisandhelpreduce variability

Deliveringpositivepatientidentification

• DAPI,abluefluorescentstain,isusedtolocateaminimumnumberofcellsandtoidentifythelocationofeachnuclei

• DAPIhelpsdifferentiatebetweenbackgroundandnuclearintensity

• ThisprocessprovidesaqualitycheckforthepresenceofcellswhenFITCintensityisnegative

ProcessingIntegratedTechnologies ProgressiveSolutiontoCommonProblems

BIO-FLASH®

Rapid-Response Chemiluminescent Analyzer for Autoimmunity

BIO-FLASHisafullmenu,randomaccessanalyzerthateliminatesbatchingandhasexcellentthroughputwithupto450resultsinasingleshift.

BIO-FLASHoffersprecisequantificationandabroaddynamicrangeusingchemiluminescenttechnology,onboardreagentsandstablecalibrationcurvestomakeeventhemost specializedtestingeasytoperform.

ProcessingIntegratedTechnologies ProgressiveSolutiontoCommonProblems

InovaDiagnostics®

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QUANTA Flash® reagents•Chemiluminescenttechnologydeliversprecisequantitation andabroadanalyticalmeasuringrange

•Cartridgebarcodeisinternallyscannedtoimportthemastercalibrationcurve,lotnumber,expirationdateandassaytype

Calibration curves•Mastercalibrationcurveuploadedthroughthereagentpackbarcode•Calibratorsareprocessedinthesamplecarousel•BIO-FLASHdeterminesastableworkingcalibrationcurve

Intuitive software and touchscreen•Simplifiestrainingandday-to-dayoperation•Statusscreenallowsimmediateaccesstosysteminformation

Eliminates isotype batching and reagent wasteStableon-boardreagentsallowforsamples toberunastheyarrive

Improves turn-around timeSimultaneousrandomaccessprocessing ofallisotypesandassaysonasinglesample

Helps reduce test send outs Makeseventhemostspecializedassaysefficient toperformwithstablecalibrationcurves

Frees up floor spaceSmallbenchtopanalyzerachieves excellentthroughput

Fullmenurandomaccess

ProcessingIntegratedWorkflow Data-DrivenLaboratoryManagement

QUANTA Link®

Workflow Management Made Easy

Apowerful,easy-to-useworkflowmanagementsystemthatgivesyouimmediatecontrol ofallyourautoimmunesampleprocessing.

Fromworklistgenerationandresultconfirmationtoqualitycontrolanddatasearch functions,thisLIScompatiblesystemmaximizeslaboratoryproductivityandprofitability.

Colorcodedbarsallowyoutoviewanddetermineworkflowprioritiesfortheentirelabonasinglescreen.

Reflexrulescanbeaddedateach decisionpoint

Command Central

ProcessingIntegratedWorkflow Data-DrivenLaboratoryManagement

QUANTALink®

AllowsthetechnologisttoviewANCAEthanol,ANCA FormalinandHEp-2resultsfromthesamepatient simultaneously.

Multi-Analyte Screen

Userdefinedatlasusedforreferenceandtraining.

Atlas

QUANTALinktransformsyourdarkroomintoa paperless,transcriptionfreeenvironment.Simplyentertheinformationdirectlyonthetouchscreen.

Paperless Interpretation

Allqualitycontrolinformationcentralizedinasingle locationbyusingLevey-Jenningsandemploying Westgardrules.

Optimize Quality Control

QUANTA Link®

Workflow management made easy

Powerfuleasy-to-use workflowmanagement systemthatgivesyou immediate control of all your autoimmune sampleprocessing.

• SeamlesslyintegrateInovainstruments totheLIS

• Efficientlycontrols instrumentworkflow

• Effectivelymanagestestordersandresults

• Optimizesquality control through trendingandanalysis

QUANTA-Lyser®

Flexibility and efficiency

TheQUANTA-Lyserfamily ofinstrumentsisthemostflexibleandefficient platformforEIAandIFA processing,withthree differentmodelstomeetthevolumerequirements ofvirtuallyanylaboratory.

• Fullyautomated, walk-awaysystemto minimizehands-ontime

• Rapidprocessing speedmaximizes throughputand increasesproductivity

• Probewasher eliminatesdisposable tipsgenerating significantcostsavings

NOVA View®

Digital IFA

AnewparadigminIFA analysisandautomation usingdigitaltechnology andproprietaryalgorithms tocapturelightintensity andcreatedigitalimages forreview.

• Positivepatient identificationforIFA samples

• Eliminatestheneed fortranscription andassociatederrors

• Reduceshands-on timewithautomatedanalysis

BIO-FLASH®

Rapid-Response Chemiluminescent Analyzer for Autoimmunity

BIO-FLASHisafullmenu,randomaccessanalyzer thateliminatesbatchingandhasexcellent throughputwithupto 450resultsinasingleshift.

• Eliminatestheneed for batching

• Fasterturnaround timewithcontinuousloading

• Calibrationcurve remainsstablefor each reagent lot

Integrated Lab Seamlesscontrolfromprocessingtoreporting

NOVA Lite® IFABarcoded Slides Positive Patient ID

Barcodedslidesenableseamlesslaboratory workflowbytracking patientdatafromsamplepreparationtoresult.

• Sampleintegrityis maintainedusinguniquenumericcodestolinkeachpatienttoa singlewell

• Assayintegrityisassuredfromsampleprocessingtoanalysis

www.inovadx.comSan Diego, CA 92131 USAPH: +1-858-586-9900 US Toll Free: 1-800-545-9495 FAX: +1-858-586-9911BIO-FLASH is a registered trademark of Biokit, S.A. QUANTA Link, QUANTA-Lyser, NOVA View, NOVA Lite and QUANTA Flash are registered trademark of Inova Diagnostics, Inc. © 2014 Inova Diagnostics, Inc. All rights reserved. .

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