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dr. Susianti, M.Sc.

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THE FUNCTIONS OF

CONNECTIVE TISSUEProviding and maintaining form in

the bodyProvide a matrix that connect and

binds the cells and organsGive support to the body

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Mesoderm migratefrom their site of origin,

surrounding and penetrating developingorgans Mesenchyme (Mesenchymal cells: characterized by ovalnucleus with prominentnucleoli and fine

chromatin)

DEVELOPMENT OF THECONNECTIVE TISSUE

PrimitiveMesenchyme

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3 COMPONENTS OF

CONNECTIVE TISSUE

CellsFibersGround Substance

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CELLS OF THE CONNECTIVETISSUE

FibroblastFibrocyteMacrophageMast Cells

Plasma CellsAdipose CellsLeukocytes

1. Macrophage(histiocyte)

2. Fibroblast3. Fibrocyte

4. Large lymphocyte5. Small lymphocyte

6. Plasma cell 7. Eosinophil

8. Pigment cell

9. Adipose cell

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FIBERS OF CONNECTIVE

TISSUE:

CollagenReticular

Elastic

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GROUND SUBSTANCE

Consist of : - glycoproteins

- proteoglycansColorless and transparant.Fills the space between cells and fibers .

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TYPES OF CONNECTIVE TISSUE

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LOOSE CONNECTIVE TISSUE

Support many structures that are normallyunder pressure and low friction.Consist of all the main component ofconnective tissue proper.The most numerous cells are fibroblasts andmacrophages, but all the other types ofconnective tissue cells are also present.

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Connective Tissue spread

1. Elastic fibers

2. Collagenous fiber3. Adiposecells

4. Fixed macrophages(histiocytes)

5. Eosinophils

6. Lymphocytes

7. Mast cells

8. Fibroblasts

9. Collagenous fibers

10. Elastic fibers

11. Fixedmacrophages

12. Capillary containingerythrocytes

13. Cytoplasmic processes14. Nucleus

15. Nucleolus

16. Nucleus

17. Vacuoles withneutral red

18. Nucleus

19. Mast cell granules

I. Fibroblast II. Fixed macrophage III. Mast cell

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DENSE CONNECTIVE TISSUE

Consist of the same components found in looseconnective tissue, but there are fewer cells andclear predominant of collagen fibers.Less flexible and far more resistant to stress

There are dense irregular and regular

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4. Nuclei oftendon cells(surface view)

4. Nuclei oftendon cells(slide view)

1. Tendon cells

2. Collagenousfibers

3. Bundle oftendon fibers

Connective Tissue

Dense regular connective tissue

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7. Skeletalmuscle fibers(t.s)

8. Interfascicularconnectivetissue

9. Tendon cells

10.Collagenousfibers

1. Bundles oftendon fibers

2. Tendon cells(nuclei)

3. Connective

tissue betweenbundles

4. Interfascicularconnective tissue

5. Bloodvessels

6. Lamellar(Paciniancorpuscle)

Connective Tissue

Dense regular connective tissue

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ELASTIC TISSUE

Compound of band less thick, parallel elasticfibers.Occurs infrequently

Present in the yellow ligaments of the vertebralcollumn and in the suspensory ligament of the

penis.

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RETICULER TISSUE

Consist of reticular fibers intimally associatedwith specialized fibroblasts called reticularcells.At the hematopoietic organs and lymphoidorgans.

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MUCOUS TISSUE

Found mainly in the umbilical cord= Whartons Jelly Has an abundance of ground substancecomposed chiefly of hyaluronic acid. Its jellylike tissue containing very few fibers.Also found in the pulp of young teeth.