Contents

PREFACE TO THE SECOND EDITION

PREFACE TO THE FIRST EDITION

ACKNOWLEDGMENTS t

INTRODUCTION

I. Disorders Mostly Limited t o the Epidermis and Stratum Corneum A. Hyperkeratosis With Hypogranulosis

1. No Inflammation lchthyosis Vulgaris

B. Hyperkeratosis With Normal or Hypergranulosis 1. No Inflammation

X-Linked lchthyosis Epidermolytic Hyperkeratosis Epidermodysplasia Verrucifamis

2. Scant Inflammation Lichen Amyloidosis and Macular Amyloidosis

C. Hyperkeratosis With Parakeratosis 1. Scant or No Inflammation

Dermatophytosis Granular Parakeratosis

D. Localized or Diffuse Hyperpigmentations 1. No Inflammation

Mucosal Melanotic Macules Ephelides (Freckles)

2. Scant Inflammation Pityriasis (Tinea) Versicolor

E. Localized or Diffuse Hypopigmentations 1. With or Without Slight Inflammation

Vitiligo References

II. Localized Superficial Epidermal or Melanocytic Proliferations A. Localized Irregular Thickening of the Epidermis

1. Localized Epidermal Proliferations Actinic Keratosis Eccrine Poroma Squamous Cell Carcinoma In Situ and Bowen's Disease Bowenoid Papulosis

XIX

XXI

XXIII

xxv

Clear Cell Squamous Cell Carcinoma In Situ Clear Cell Acanthoma

2. Superficial Melanocytic Proliferations Superjicial Melanocytic Ne.vi and Melanomas Pigmented Spindle Cell N&US

Acral-Lentiginous Melanoma B. Localized Lesions With t'hinnifig of the Epidermis

1. With Melanocytic Proliferation '

Lentigo Maligna Melanoma,, In Situ or Microinvasive Recurrent ("Persistent") Nevus, Lentiginous Patterns Superficial Atypical Melanocytic Proliferations of Uncertain SigniJicance, Lentiginous Patterns

2. Without Melanocytic Proliferation Atrophic Actinic Keratosis Porokeratosis

C. Localized Lesions With Elongated Rete Ridges 1. With Melanocytic Proliferation

Actinic Lentigo \

Lentigo Simplex Lentiginous Junctional Nevus Nevus Spilus Junctional or Superjicial Compound Dysplastic Nevi

2. Without Melanocytic Proliferation Epidermal Nevus Seborrheic Keratosis Acanthosis Nigricans

D. Localized Lesions With Pagetoid Epithelial Proliferation 1. Keratinocytic Proliferations

Pagetoid Squamous Cell Carcinoma In Situ Clonal Seborrheic Keratosis

2. Melanocytic Proliferation Melanoma In Situ or Microinvasive, Superficial Spreading Type Recurrent Nevus (Pseudomelanoma), Pagetoid Patterns Junctional Spitz Tumor (Nevus) with Pagetoid Proliferation SuperjiciaVIntraepidemuzl Atypical Melanocytic Proliferations of Uncertain SigniJicance, Pagetoid Patterns

3. Glandular Epithelial Proliferations Paget's Disease

4. Lymphoid Proliferations E. Localized Papillomatous Epithelial Lesions

1. With Viral Cytopathic Effects Verruca Vulgaris Verruca Plana Deep Palrnoplantar Warts (Myrmecia) Condyloma Acuminatum Molluscum Contagiosum Parapox Virus Infections (Milkers' Nodules, Orf)

2. No Viral Cytopathic Effect Seborrheic Keratosis Confluent and Reticulated Papillomatosis (Gougerot-Carteaud)

F. Irregular Proliferations Extending into the Superficial Dermis 1. Squamous Differentiation

Inverted Follicular Keratosis 2. Basaloid Differentiation

Basal Cell Carcinoma

G. Superficial Polypoid Lesions 1. Melanocytic Lesions

Polypoid Dermal and Compound Nevi 2. Spindle Cell and Stromal Lesions

Neurojbroma Fibroepithelial Polyp

References

Ill. Disorders of the Superficial Cutaneous Reactive Unit A. Superficial Perivascular Dermatitis

1. Superficial Perivascular Dermatitis, Mostly Lymphocytes Viral Exanthem Tinea Versicolor Lupus Erythematosus, Acute Guttate Parapsoriasis

la. Superficial Perivascular Dermatitis with Eosinophils Morbilliform Drug Eruption Allergic ~rticariat Reaction (Morbilliform Drug Eruption) Urticaria Urticaria1 Bullous Pemphigoid

lb. Superficial Perivascular Dermatitis with Neutrophils Erysipelas Erysipelas/Cellulitis

lc. Superficial Perivascular Dermatitis with Plasma Cells Secondary Syphilis Kaposi's Sarcoma, Patch Stage

Id. Superficial Perivascular Dermatitis, with Extravasated Red Cells Pityriasis Rosea Pityriasis Lichenoides Pigmented Purpuric Dermatosis

le. Superficial Perivascular Dermatitis, Melanophages Prominent Postinflammatory Hyperpigmentation

2. Superficial Perivascular Dermatitis, Mast Cells Predominant Urticaria Pigrnentosa

B. Superficial Dermatitis With Spongiosis (Spongiotic Dermatitis) 1. Spongiotic Dermatitis, Lymphocytes Predominant

Nummular Dermatitis (Eczema) Eczematous Dermatitis Meyerson ' s Nevus

la. Spongiotic Dermatitis, with Eosinophils Allergic Contact Dermatitis Allergic Contact Dermatitis

lb. Spongiotic Dermatitis, with Plasma Cells lc. Spongiotic Dermatitis, with Neutrophils

Seborrheic Dermatitis C. Superficial Dermatitis With Epidermal Atrophy (Atrophic Dermatitis)

1. Atrophic Dermatitis, Scant Inflammatory Infiltrates Aged Skin Radiation Dermatitis

2. Atrophic Dermatitis, Lymphocytes Predominant Poikiloderma Atrophicans Vasculare Dermatomyositis

3. Atrophic Dermatitis with Papillary Dermal Sclerosis Lichen Sclerosus Et Atrophicus

D. Superficial Dermatitis With Psoriasiform Proliferation (Psoriasiform Dermatitis)

1. Psoriasiform Dermatitis, Mostly Lymphocytes Pityriasis Rubra Pilaris Mycosis Fungoides, Patch-Plaque Stage Parapsoriasis

la. Psoriasiform Dermatitis, with Plasma Cells Lichen Simplex Chronicus

lb. Psoriasiform Dermatitis, with Eosinophils Chronic Allergic Dermatitis

2. Psoriasiform Dermatitis, Neutrophils Prominent (Neutrophilic/Pustular Psoriasiform Dermatitis) Psoriasis Vulgaris

3. Psoriasiform Dermatitis, with Epidermal Pallor and Necrosis ("Nutritional Pattern" Dermatoses) Necrolytic Migratory 'Erythema (Glucagonoma Syndrome) Necrolytic Acral Erythema Pellagra

E. Superficial Dermatitis With Irregular Epidermal Proliferation ("Hypertrophic Dermatitis")

1. Hypertrophic Dermatitis, Lymphocytes Predominant Prurigo Nodularis

la. Irregular Epidermal Proliferation, Plasma Cells Present Actinic Keratosis

2. Irregular Epidermal Proliferation, Neutrophils Prominent Keratoacanthoma

3. Irregular Epidermal Proliferation, Above a Neoplasm Verrucous Melanoma

F. Superficial Dermatitis With Lichenoid Infiltrates (Lichenoid Dermatitis) 1. Lichenoid Dermatitis, Lymphocytes Exclusively

Lichen Planus Graft versus Host Disease Mycosis Fungoides, PatcWPlaque Stage

2. Lichenoid Dermatitis, Lymphocytes Predominant Lichen Planus-like Keratosis (Benign Lichenoid Keratosis)

2a. Lichenoid Dermatitis, Eosinophils Present Lichenoid Drug Eruptions

2b. Lichenoid Dermatitis, Plasma Cells Present Lichenoid Actinic Keratosis Secondary Syphilis

2c. Lichenoid Dermatitis, with Melanophages 3. Lichenoid Dermatitis, Histiocytes Predominant

Lichen Nitidus 4. Lichenoid Dermatitis, Mast Cells Predominant

Urticaria Pigmentosa, Lichenoid Examples 5. Lichenoid Dermatitis, with Dermal Fibroplasia

Mycosis Fungoides, Patch Stage G. Superficial Vasculitis and Vasculopathies

1. Neutrophilic Vasculitis Cutaneous Necrotizing (Leukocytoclastic) Vasculitis Gonococcemia

2. Mixed Cell and Granulomatous Vasculitis Granuloma Faciale

3. Vasculopathies with Lymphocytic Inflammation Pigmented Purpuric Dermatoses

4. Vasculopathies with Scant Inflammation Stasis Dermatitis Stasis Dermatitis

5. Thrombotic, Embolic and Other Microangiopathies Lupus Anticoagulant and Antiocardiolipin Syndromes Cryoglobulinernia

H. Superficial Dermatitis With Interface Vacuoles (Interface Dermatitis) 1. Vacuolar Dermatitis, Apoptotic/Necrotic Cells Prominent

Erythema Multiforme Fixed Drug Eruption Graft versus Host Disease, Acute

2. Vacuolar Dermatitis, Apoptotic Cells Usually Absent Dermatomyositis

3. Vacuolar Dermatitis, Variable Apoptosis Subacute Cutaneous Lupus Erythematosus

4. Vacuolar Dermatitis, Basement Membranes Thickened Discoid Lupus Erythematosus

References

Acantholytic, Vesicular, and Pustular Disorders A. Subcorneal or lntracorneal Separation

1. Sub/Intracorneal Separation, Scant Inflammatory Cells pemphigus Foliaceus

2. SubIIntracorneal Separation, Neutrophils Prominent Impetigo Contagiosa Folliculitis with Subcorneal Pust~ile Formation Acute Generalized Exanthernatous Pustulosis

3. SubIIntracorneal Separation, Eosinophils Predominant Erythema Toxicum Neonatorum

B. lntraspinous Keratinocyte Separation, Spongiotic 1. Intraspinous Spongiosis, Scant Inflammatory Cells

Friction Blister 2. Intraspinous Spongiosis, Lymphocytes Predominant

Dyshidrotic Dermatitis (Eczema) 2a. Intraspinous Spongiosis, Eosinophils Present

Acute Contact Dermatitis Bullous Pemphigoid, Urticaria1 Phase Incontinentia Pigmenti

3. Intraspinous Spongiosis, Neutrophils Predominant Dermatophy tosis

C. Intraspinous Keratinocyte Separation, Acantholytic 1. Intraspinous Acantholysis, Scant Inflammatory Cells

Familial Benign Pemphigus (Hailey-Hailey Disease) Transient Acantholytic Derinatosis (Grover's Disease)

2. Intraspinous Acantholysis, Predominant Lymphocytes Herpes Simplex Varicella-Zoster Infection Toxic Epidermal Necrolysis and Erythema Multiforme with Intraepidermal Vesiculation Paraneoplastic Pemphigus

2a. Intraspinous Acantholysis, Eosinophils Present Pemphigus Vegetans

3. Inuaspinous Separation, Neutrophils or Mixed Cell Types Immunoglobulin A Pemphigus

D. Suprabasal Keratinocyte Separation 1. Suprabasal Vesicles, Scant Inflammatory Cells

Keratosis Follicularis (Darier's Disease) Warty Dyskeratoma

2. Suprabasal Separation, Lymphocytes and Plasma Cells Acantholytic Actinic Keratosis

3. Suprabasal Vesicles, Lymphocytes and Eosinophils Pemphigus Vulgaris

E. Subepidermal Vesicular Dermatitis 1. Subepidermal Vesicles, ScantfNo Inflammation

Porphyria Cutanea Tarda and Other Porphyrlas 2. Subepidermal Vesicles, Lymphocytes Predominant

Bullous Lichen Planus Polymorphous (Polymorphic) Light Eruption Bullous Dermatophytosis Lichen Sclerosus et ~ l r o ~ h i c u s

3. Subepidermal Vesicles, Eosinophils Prominent Bullous Pemphigoid Bullous Drug Eruption Herpes Gestationis

4. Subepidermal Vesicles, Neutrophils Prominent Dermatitis Herpetiformis Linear Immunoglobulin A Dermatosis Bullous Lupus Erythematosus

5. Subepidermal Vesicles, Mast Cells Prominent Bullous Mastocytosis

References

, Perivascular, Diffuse, and Granulomatous Infiltrates of the Reticular Dermis A. Superficial and Deep Perivascular Infiltrates Without Vasculitis

1. Perivascular Infiltrates, Lymphocytes Predominant Erythema Annulare Centrifugum Erythema Chronicum Migrans Tumid Lupus Erythematosus

2. Perivascular Infiltrates, Neutrophils Predominant Cellulitis

3. Perivascular Infiltrates, Lymphocytes, and Eosinophils Papular Urticaria Pruritic Urticaria1 Papules and Plaques of Pregnancy

4. Perivascular Infiltrates, with Plasma Cells Secondary Syphilis Tertiary Syphilis Morphea

5. Perivascular Infiltrates, Mixed Cell Qpes Erythema Chronicum Migrans

B. Vasculitis and Vasculopathies 1. Vascular Damage, Scant Inflammatory Cells

Degos' Syndrome 2. Vasculitis, Lymphocytes Predominant

Pernio Pityriasis Lichenoides Cytomegalovirus Infection Erythema Chronicum Migrans

3. Vasculitis, Neutrophils Prominent Polyarteritis Nodosa and Microscopic Polyangiitis Leukocytoclastic Vasculitis Erythema Elevatum Diutinum

4. Vasculitis, Mixed Cell Types andlor Granulomas Churg-Strauss Syndrome (Allergic Granulomatosis) Papulonecrotic Tuberculid

5. Thrombotic and Other Microangiopathies Calciphylaxis Livedo Reticularis

C. Diffuse Infiltrates of the Reticular Dermis 1. Diffuse Infiltrates, Lymphocytes Predominant

Jessner's Lymphocytic Injiltration of the Skin Leukemia Cutis

2. Diffuse Infiltrates, Neutrophils Predominant Acute Febrile Neutrophilic Dermatosis (Sweet's Syndrome) Neutrophilic Dermatosis of the Dorsal Hands Erysipelas '\

3. Diffuse Infiltrates, "Histiocytoid" Cells Predominant Lepromatous Leprosy LQngerhans Cell Histiocytosis (Histiocytosis X ) Xanthelasma

4. Diffuse Infiltrates, Plasma Cells Prominent Secondary Syphilis

5. Diffuse Infiltrates, Mast Cells Predominant 6. Diffuse Infiltrates, Eosinophils Predominant

Eosinophilic Cellulitis (Wells Syndrome) Tick Bite

7. Diffuse Infiltrates, Mixed Cell Types Cutaneous Leishmaniasis

8. Diffuse Infiltrates, Pigment Cells Nevi of Ota and Ito and D e m l Melanocyte Hamartoma

9. Diffuse Infiltrates, Extensive Necrosis Gangrenous Ischemic Necrosis

D. Diffuse or Nodular Infiltrates of the Reticular Dermis with Epidermal Proliferation

1. Epidermal Proliferation with Mixed Cellular Infiltrates North American Blastomycosis Deep Fungal Infections-General

E. Nodular Inflammatory Infiltrates Of The Reticular Dermis - Granulomas, Abscesses, and Ulcers

1. Epithelioid Cell Granulomas without Necrosis Sarcoidosis Lupus Vulgaris

2. Epithelioid Cell Granulomas with Necrosis Tuberculosis Tuberculoid Leprosy Lupus Miliaris Disseminatus Faciei (Granulomatous Rosacea)

3. Palisading Granulomas Granuloma Annulare Necrobiosis Lipoidica Diabeticorum Necrobiotic Xanthogranuloma with Paraproteinemia Rheumatoid Nodules Palisaded Neutrophilic and Granulomatous Dermatitis

4. Mixed Cell Granulomas Foreign-body Reactions

5. Inflammatory Nodules with Prominent Eosinophils Angiolymphoid Hyperplasia with Eosinophilia, and Kimura's Disease Scabetic Nodule

6. Inflammatory Nodules with Mixed Cell Types Sporotrichosis Atypical Mycobacteria

7. Inflammatory Nodules with Necrosis and Neutrophils (Abscesses) Botryomycosis Chromoblastomycosis

8. Inflammatory Nodules with Prominent Necrosis Aspergillosis

9. Chronic Ulcers and Sinuses Involving the Reticular Dermis Chancroid Pyoderma Gangrenosum Chondrodermatitis Nodularis Helicis

F. Dermal Matrix Fiber Disorders 1. Fiber Disorders, Collagen Increased

Scleroderma \

Radiation Dermatitis Nephrogenic Fibrosing Dermopathy Regressing Melanoma Superjcial Scar (E.g., Biopsy Site Reaction)

2. Fiber Disorders, Collagen Reduced Focal Dermal Hypoplasia Syndrome (Goltz)

3. Fiber Disorders, Elastin Increased or Prominent Pseudoxanthorna Elasticum

4. Fiber Disorders, Elastin Reduced Macular Atrophy (Anetoderma)

5. Fiber Disorders, Perforating Elastosis Pe$orans Serpiginosum Reactive Perjorating Collagenosis Pegorating Folliculitis

G. Deposition of Material in the Dermis 1. Increased Normal Nonfibrous Matrix Constituents

Digital Mucous Cysts and Focal Mucinosis Mucinosis in Lupus Erythematosus Myxedema Scleredema Scleromyxedema

2. Increased Material Not Normally Present in the Dermis Gout Oxalosis Colloid Milium Idiopathic Calcinosis Cutis Cryoglobulinemia Keratin Granuloma Suture Granuloma Minocycline Pigmentation

3. Parasitic Infestations of the Dermis and/or Subcutis Larva Migrans Eruption

References

Tumors and Cysts of the Dermis and Subcutis A. Small Cell Tumors

1. Tumors of Lymphocytes or Hemopoietic Cells Cutaneous B-Cell Lymphoma

5. Inflammatory Nodules with Prominent Eosinophils Angiolymphoid Hyperplasia with Eosinophilia, and Kimura's Disease Scabetic Nodule

6. Inflammatory Nodules with Mixed Cell Types Sporotrichosis Atypical Mycobacteria

7. Inflammatory Nodules with Necrosis and Neutrophils (Abscesses) Botryomycosis Chrornoblastomycosis

8. Inflammatory Nodules with Prominent Necrosis Aspergillosis

9. Chronic Ulcers and Sinuses Involving the Reticular Dermis Chancroid Pyoderrna Gangrenosum Chondroderrnatitis Nodularis Helicis

F. Dermal Matrix Fiber Disorders 1. Fiber Disorders, Collagen Increased

Scleroderma 1

Radiation Dermatitis Nephrogenic Fibrosing Dermopathy Regressing Melanoma Superjicial Scar (E.g., Biopsy Site Reaction)

2. Fiber Disorders, Collagen Reduced Focal Dermal Hypoplasia Syndrome (Goltz)

3. Fiber Disorders, Elastin Increased or Prominent Pseudoxanthoma Elasticum

4. Fiber Disorders, Elastin Reduced Macular Atrophy (Anetoderma)

5. Fiber Disorders, Perforating Elastosis Perforans Serpiginosum Reactive Perforating Collagenosis Perforating Folliculitis

G. Deposition of Material in the Dermis 1. Increased Normal Nonfibrous Matrix Constituents

Digital Mucous Cysts and Focal Mucinosis Mucinosis in Lupus Erythernatosus Myxedema Scleredema Scleromyxedema

2. Increased Material Not Normally Present in the Dermis Gout Oxalosis Colloid Miliurn Idiopathic Calcinosis Cutis Cryoglobulinemia Keratin Granuloma Suture Granuloma Minocycline Pigmentation

3. Parasitic Infestations of the Dermis and/or Subcutis Larva Migrans Eruption

References

Tumors and Cysts of the Dermis and Subcutis A. Small Cell Tumors

1. Tumors of Lymphocytes or Hernopoietic Cells Cutuneous B-Cell Lymphoma

Cutaneous Diffuse B-Cell Lymphoma Cutaneous T-cell Lymphoma, Tumor Stage

2. Tumors of Lymphocytes and Mixedcell Types B-Cell Cutaneous Lymphoid Hyperplasia (Pseudolymphoma or Lymphocytoma Cutis)

3. Tumors of Plasma Cells Cutaneous Plasmacytoma and Multiple Myeloma

4. Small Round Cell Tumors Cutaneous Small Cell Undifferentiated Carcinoma (Merkel Cell Tumor) Metastatic Small Cell Carcinoma

B. Large Polygonal and Round Cell Tumors 1. Squamous Cell Tumors

Squamous Cell Carcinoma, Deep Keratoacanthorna Inverted Follicular Keratosis Pseudoepitheliomatous Hyperplasia Proliferating Trickilemmal Cyst (Pilar Tumor) Prurigo Nodularis

2. Adenocarcinomas Metastatic Adenocarcinoma Metastatic Pulmonary Adenocarcinoma Metastatic Mammary Carcinoma

3. Melanocytic Tumors 3a. Melanocytic Lesions with Little or No Cytologic Atypia

Melanocytic Nevi, Acquired, and Congenital Types Acquired Nevi Congenital Nevus Acral Nevus Balloon Cell Nevus Halo Nevus Blue Nevus Cellular Blue Nevus

3b. Melanocytic Lesions with Cytologic Atypia Deep Penetrating Nevus Spitz Tumor/Nevus Nodular Melanoma Nevoid Melanoma Metastatic Malignant Melanoma Metastatic Malignant Melanoma, Satellite Lesion Epidermotropic Metastatic Melanoma Pigmented Epithelioid Melanocytoma/Epithelioid Blue Nevus Melanocytic Tumor of Uncertain Malignant Potential

4. Eccrine Tumors 4a. Circumscribed, Symmetrical Eccrine Tumors

Eccrine Spiradenoma Cylindroma Poroma Syringoma Nodular Hidradenoma Clear Cell Syringoma Chondroid Syringoma

4b. Infiltrative, Asymmetric EccrineTumors Microcystic Adnexal Carcinoma Mucinous Eccrine Carcinoma Digital Papillary Adenocarcinoma

5. Apocrine Tumors Tubular Apocrine Adenoma Syringocystadenoma Pupilliferum

6. Pilar Tumors Trichoepithelioma Desmoplastic Trichoepithelioma Dilated Pore of Winer Pilar Sheath Acanthoma Trichilemmoma Trichofolliculoma Fibrofolliculoma Trichoadenoma Pilomatricoma Trichoblastoma

7. Sebaceous Tumors Sebaceous Adenom and Sebaceous Epithelioma (Sebaceoma) Sebaceous Hyperplasia Nevus Sebaceous of hdassohn Sebaceous Epithelioma Sebaceous Carcinoma

8. "Histiocytoid" Tumors Xanthomas and Xanthelasma Xanthelasma Eruptive Xanthoma Verrucifom Xanthoma Juvenile Xanthogranuloma Reticulohistiocytosis Metastatic Renal Cell Carcinoma

9. Tumors of Large Lymphoid Cells Cutaneous C D ~ O + (&I+) Anaplastic Large Cell Lymphoma Lymphomatoid Papulosis Leukemia Cutis

10. Mast Cell Tumors Urticaria Pigmentosa, Nodular Lesions

11. Tumors with Prominent Necrosis Epithelioid Sarcoma

12. Miscellaneous and Undifferentiated Epithelial Tumors Granular Cell Tumor Cellular Neurothekeoma Metastatic Malignant Melanoma

C. Spindle Cell, Pleomorphic and Connective Tissue Tumors 1. Fibrohistiocytic Spindle Cell Tumors

la. Fibrohistiocytic Tumors with Minimal or No Atypia Dermatofibroma Cellular Dermatofibroma Sclerosing/Angiomatoid Spitz Nevus (Desrnoplastic Spitz Nevus) Dermatojibrosarcoma Protuberans Fibrous Papule (Angiofibroma) Recurrent Infantile Digital Fibromatosis Keloid Acquired Digital Fibrokeratoma Giant Cell Tumor of Tendon Sheath Nodular Fasciitis

lb. Fibrohistiocytic Tumors with High-Grade Atypia Atypical Fibroxanthoma Malignant Fibrous Histiocytom

lc. Lesions with Myxoid Changes Mucocele Digital Mucous Cyst Cutaneous Myxoma

2. SchwanniadNeural Spindle Cell Tumors Neurojbromas Neurojbromatosis Schwannoma (Neurilemmoma) Palisaded Encapsulated Neuroma Accessory Digit

3. Spindle Cell Tumors of Muscle Leiomyomas Angioleiomyoma Smooth Muscle Harnartoma Leiomyosarcoma

4. Melanocytic Spindle Cell Tumors Desmoplastic Melanoma

5. Tumors and Proliferations of Angiogenic Cells Pyogenic Granuloma (Lobular Capillary Hemangioma) Intravascular Papillary Endothelial Hyperplasia (Masson's Hemangio-Endotheliome Vegetant Intravasculaire) Stasis Dermatitis with Vascular Proliferation (Acroangiodermatitis, Pseudo-Kaposi's Sarcoma) Kaposi's Sarcoma DifSuse Dermal Angiomatosis Cutaneous Angiosarcoma Epithelioid Hemangioendothelioma Targetoid Hemsiderotic Hemangioma (Hobnail Hemangioma) Angiokeratoma Arteriovenous Hemangiorna Cavernous Hemangioma Cherry Hemangioma Microvenular Hemangioma Cutaneous Lymphangioma Venous Luke Glomangioma Subungual Glomus Tumor

6. Tumors of Adipose Tissue Nevus Lipomatosus Superjicialis Lipoma Angiolipomas Spindle Cell Lipoma Pleomorphic Lipoma Liposarcoma

7. Tumors of Cartilaginous Tissue 8. Tumors of Osseous Tissue

Albright's Hereditary Osteodystrophy and Osteoma Cutis D. Cysts of the Dermis and Subcutis

1. Pilar Differentiation Epidermal or Infundibular Cyst Trichilernmal (Pilar) Cyst Steatocystoma Vellus Hair Cyst

2. Eccrine and Similar Differentiation Eccrine Hidrocystoma Median Raphe Cyst

Bronchogenic Cyst Cutaneous Endometriosis

3. Apocrine Differentiation Apocrine Hidrocystoma Hidrudenoma Pupilliferum

References

VII. Inflammatory and Other Benign Disorders of Skin Appendages A. Pathology Involving Hair Follicles

1. Scant Inflammation Androgenetic Alopecia Trichotillomania Telogen Efluvium Keratosis Pilaris Scurvy

2. Lymphocytes Predominant Alopecia Areata Lichen Planopiluris 't

Central Centrifugal Cicatricial Alopecia Discoid Lupus Erythematosus of the Scalp Alopecia Mucinosu Rosacea

3. With Prominent Eosinophils Eo.rinophilic Pustular Folliculitis

4. Neutrophils Prominent Acute Deep Folliculitis (Furuncle) Tinea Capitis Mujocchi's Granuloma Herpes Simplex Viral Folliculitis

5. Plasma Cells Prominent Folliczllitis (Acne) Keloidalis Nuchae Tinea Capitis

6. Fibrosing and Suppurative Follicular Disorders Follic~llar Occlusion Triad (Hidradenitis Suppurativa, Acne Conglobatu, und Perifolliculitis Capitis Abscedens Et Suffodiens) Hidradenitis S~ippurativa Dissecting Cellulitis of the Scalp Fofficufitis Decalvans

B. Pathology Involving Sweat Glands 1. Scant Inflammation

Eccrine Nevus 2. Lymphocytes Predominant

Lichen Striatus 2a. With Plasma Cells

Lupus Erythematosus 2b. With Eosinophils

Arthropod Bite 3. Neutrophils Predominant

Neutrophilic Eccrine Hidradenitis Idiopathic Recurrent Palmoplantar Hidradenitis

C. Pathology Involving Nerves 1. Lymphocytic Infiltrates 2. Mixed Inflammatory Infiltrates

Nerve Involvement in Leprosy Erythema Chronica Migrans with Nerve Involvement Arthropod Bite Reaction with Newe Involvement

3. Neoplastic Infiltrates Neurotropic Melanoma

D. Pathology of the Nails 1. Lymphocytic Infiltrates

Acral Lentiginous Melanoma 2. Lymphocytes with Neutrophils

Onychomycosis 3. Vesiculobullous Diseases

Darier's Disease 4. Parasitic Infestations

Scabies References

VIII. Disorders of t h e Subcutis A. Subcutaneous Vasculitis and Vasculopathy (Septal or Lobular)

1. Neutrophilic Vasculitis Subcutaneous Polyarteritis Nodosa

2. Lymphocytic "~as'tulitis" 3. Granulomatous Vasculitis

Erythema Induratum (Nodular Vasculitis) B. Septal Panniculitis Without Vasculitis

1. Septal Panniculitis, Lymphocytes and Mixed Infiltrates Erythema Nodosum

2. Septal Panniculitis, Granulomatous Subcutaneous Granuloma Annulare

3. Septal Panniculitis, Sclerotic Scleroderma and Morphea

C. Lobular Panniculitis Without Vasculitis 1. Lobular Panniculitis, Lymphocytes Predominant

Lupus Erythematosus Panniculitis 2. Lobular Panniculitis, Lymphocytes, and Plasma Cells 3. Lobular Panniculitis, Neutrophilic 4. Lobular Panniculitis, Eos~nophils Prominent 5. Lobular Panniculitis, Histiocytes Prominent

Histiocytic Cytophagic Panniculitis (Subcutaneous T-cell Lymphoma with Hemophagocytic Syndrome)

6. Lobular Panniculitis, Mixed with Foam Cells Relapsing Febrile Nodular Nonsuppurative Panniculitis (Weber-Christian Disease)

7. Lobular Panniculitis, Granulomatous Subcutaneo~~s Sarcoidosis

8. Lobular Panniculitis, Crystal Deposits, Calcifications Subcutaneous Fat Necrosis of the Newborn Calcifying Panniculitis (Calciphylaxis)

9. Lobular Panniculitis, Necrosis Prominent Subcutaneous Nodular Fat Necrosis in Pancreatic Disease

10. Lobular Panniculitis, Embryonic Fat Pattern Localized Lipontrophy and Lipodystrophy

11. Lobular Panniculitis, Lipomembranous Lipomembranous Change or Lipomembranous Panniculitis

D. Mixed Lobular and Septal Panniculitis 1. With Hemorrhage or Sclerosis

Panniculitis due to Physical or Chemical Agents 2. With Many Neutrophils

Necrotizing Fasciitis

3. With Many Eosinophils Eosinophilic Fasciitis (Shulman's Syndrome)

4. With Many Lymphocytes Subcutaneous Panniculitic or Lipotropic T-cell Lymphoma

5. With Cytophagic Histiocytes Sinus Histiocytosis with Massive Lymphadenopathy (, Rosai-Dorfman)

6. With Granulomas Mycobacterial Panniculitis Erythema Nodosum Leprosum (Type 2 Leprosy Reaction)

E. Subcutaneous Abscesses 1. With Neutrophils

Phaeohyphornycotic Cyst References