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Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific target cells in a different organ

Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

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Page 1: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

Copyright © 2009 Pearson Education, Inc.

Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific target cells in a different organ

Page 2: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

Copyright © 2009 Pearson Education, Inc.

Figure 13.4 A negative feedback loop involving a hormone.

Page 3: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

Copyright © 2009 Pearson Education, Inc.

Figure 13.1 Components of the human endocrine system. (DON’T NEED TO KNOW ALL DETAILS)

Page 4: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

Copyright © 2009 Pearson Education, Inc.

Figure 13.1 Components of the human endocrine system. (KNOW THESE 9 ORGANS)

1

3

4

6

52

7

9

8

Page 5: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

Copyright © 2009 Pearson Education, Inc.

Figure 13.12 The thyroid and parathyroid glands.

Page 6: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

Copyright © 2009 Pearson Education, Inc.

Steroid Hormones

• cortisol, cortisone

• aldosterone

• testosterone

• estrogen

• progesterone

Page 7: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

Copyright © 2009 Pearson Education, Inc.

Figure 13.2 Mechanism of steroid hormone action on a target cell.

Page 8: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

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Figure 13.3 Mechanism of nonsteroid hormone action on a target cell.

Page 9: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

Copyright © 2009 Pearson Education, Inc.

Table 13.2 Hormones of the endocrine glands other than the hypothalamus and pituitary (1 of 2)

Page 10: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

Copyright © 2009 Pearson Education, Inc.

Table 13.2 Hormones of the endocrine glands other than the hypothalamus and pituitary (2 of 2)

Page 11: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

Copyright © 2009 Pearson Education, Inc.

Table 13.1 Hormones of the pituitary gland

Page 12: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

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Figure 13.8 Effect of growth hormone on body growth.

Page 13: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

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Figure 13.14 A goiter caused by dietary iodine deficiency.

Page 14: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

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Endocrine glands that are composed of nerve cells

• Posterior pituitary

• Adrenal medulla

Page 15: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

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Figure 13.5 Posterior pituitary lobe and hypothalamus. (2 of 2)

Page 16: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

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Figure 13.7 The relationship between the hypothalamus and the anterior pituitary gland.

Page 17: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

Thyroid follicle

Page 18: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

Thyroid follicle

Colloid Follicular epithelium

Page 19: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

Acini Pancreatic islets

Duct

Page 20: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

Acini Ducts Pancreatic islets

Page 21: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

Posterior pituitary

Anterior pituitary

Page 22: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

Adrenal capsule

Adrenal cortex

Adrenal medulla

Page 23: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

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Figure 7.2 Blood.

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• Anti-coagulents: inhibit blood clotting

• Must be added to blood immediately after collection

• Most common: Heparin and EDTA

Page 25: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

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Table 7.1 Composition of blood

Page 26: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

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Figure 7.1 The transport role of the circulatory system.

Page 27: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

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Figure 7.5 The production of blood cells and platelets.

Page 28: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

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Figure 7.3 Red blood cells.

Page 29: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

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Figure 7.7 A neutrophil attacks a Bacillus bacterium.

Page 30: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

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Figure 17.10 Leukocytes.

(a) Neutrophil; multilobed nucleus

(b) Eosinophil; bilobed nucleus, red cytoplasmic granules

(c) Basophil; bilobed nucleus, purplish-black cytoplasmic granules

(d) Small lymphocyte; large spherical nucleus

(e) Monocyte; kidney-shaped nucleus

Page 31: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

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Abundance of various WBC

Neutrophils ~65%

Lymphocytes ~25%

Monocytes ~8%

Eosinophils ~3%

Basophils ~0.5%

There are about 1,000 times more RBC than the total of WBC

Page 32: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

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Functions of leukocytes (WBC)

• Lymphocytes – specific immune response (make antibodies and antibody-like proteins)

• Eosinophils – protect against parasites

• Basophils – contribute to allergic response

• Platelets – initiate blood clotting

• Neutrophils and Monocytes – protect against bacteria and fungi

Page 33: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

Copyright © 2009 Pearson Education, Inc.

Page 34: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

Neutrophil

Nucleus

Red blood cell

Page 35: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

Neutrophil

Basophil

Red blood cells

Page 36: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

Nucleus

Lymphocyte

Red blood cell

Page 37: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

Red blood cells Platelets

Monocyte Nuclei

Neutrophil

Page 38: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

Nucleus Monocyte

Red blood cell

Page 39: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

Red blood cell

Eosinophil

Nucleus

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Figure 7.8 The stages of hemostasis.

Page 41: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

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Figure 7.9 Magnified view of a developing clot, showing red blood cells trapped in a network of fibrin fibers.

Page 42: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

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Figure 7.12 Characteristics of the four major blood types of the ABO typing system.

Page 43: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

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Figure 7.11 How antibodies recognize and inactivate foreign cells.

Page 44: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

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Figure 7.13 How Rh factor incompatibility can affect a fetus.

Page 45: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

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• Why are antibodies to erythrocyte antigens A and B not a problem for pregnancy (like anti-Rh antibodies)?

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Figure 7.14 Blood typing for ABO blood types.

Page 47: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

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Page 48: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

Copyright © 2009 Pearson Education, Inc.

Page 49: Copyright © 2009 Pearson Education, Inc. Hormone: A molecule produced in one organ that is secreted into the blood, and has a physiological effect on specific

Copyright © 2009 Pearson Education, Inc.