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    Adrenal Dis:

    Pt. on steroids:

    Any persons who was during the last 2 years on 20mg

    preduisolone or more for 2 weeks or more is considered as

    adrenal gland suppressed person.

    Before Surgery: Give 100 mg of hydrocortisone.

    during op: 100mg of Hydrocortisone in 1L of

    RL /D5

    Post op 100mg hydrocortison 16h.

    dose reduced every day.

    Pt need ext of tooth = double the dose before procedure.

    Give prophylactic Ab before procedures.

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    For minor procedures:

    Give 1. V hydrocortisone 100mg or 20mg prednisolone 2-hr of

    procedures.

    For long procedures: give 100 mg then 50mg / 6hrs

    For major surgery: 100mg then 50mg/ 6hr for 72 hours.

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    Adrenocorticonal Dis:

    1) Cushings dis: high Glugocorticoid central obesityhyperglycemia, hypertension, osteoporosis/ weakness

    2) 2Adrenal insuffecancydue to ACTHsteroid therapy.

    3) Conn ,s dis: high Aldosteron.

    4) addisonns disease low glucocorticoid

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    Pt on Cortisone:

    Peptic ulcers.

    Susceptibility to infection (need Ab cover).

    Succeptability to CA.

    Hypertensive. Hyperglycemic.

    Acne + fat redistribution.

    Mood s + Psychosis.

    Proximal myopathy.

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    Hyper thyroidisim: T3 T4

    Graves dis.

    Heat in tolerance.

    wt. loss

    Irritability ,,, tremor. Diahrrea.

    Goiters/ enlarged thyroid glands.

    Warm hands tachycardia.

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    Hypothyroidism:

    Hashimottos dis

    Cold intolerance.

    Hoarsness of v.

    wt gain dementia + constipation hair loss.

    Macroglossia mexydema.

    Anemia.

    G. A. + Sedative mexydems coma

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    Management

    HypothyrodismHypothyoideuthyroid.

    If emergency ttt give 50mg 1.v thyroxine.

    Pt. sensitive to narcotics respiratory depression.

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    Hyperthyrodism

    Management: To reach euthyriod. If emergency ttt (Thyroid storm)

    give antithyroid / thiouracil.

    glucose I. v.

    hydorocortsion.

    propranolal B blocker 3mg 94

    lodide 1.v 1-2 slowly. Cold mattress

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    Hyper lhyroidism common in Hypolhyruidism cretinismExpophlhalmous irriversable my mexydemaEye lid lag, jerky movement delayed toothemption

    Thyroid swelling bradycardiaEarly tooth eruption hypotension

    OsteoporosisAlv. Bone lossWarm moist hand

    Tremor dry hands

    Diahrrea constipationLoss of wt wt gainHeat intolerance cold intoleranceApettite apettileMetabolism metabolism

    Nervous person alopecin

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    Carbimozole : Oral Ulcers b/ c agranlocytosis

    Thiouracil Lymphopenia affect platletsso CBC

    Bleeding profile.Delay TT until euthyroid

    Give pilocarpine with felypression instead of adrenaline

    Avoid

    Povidine iodine b/c I is taken by lhyrold.

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    Hypothroidism

    Avoid I Avoid G. A : should be eulhyroid. Avoid opoids + benzodia zipine.

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    PregnancyPregnancy

    -Its an altered physiologic state and not a pathologic entity.- Consult her physician.- Do procedures on 2nd trimester.- Keep up right position.

    - Avoid x-ray use sheild.- Avoid felypressin (contracture).

    Pilocarpine (methymo globenemia) :

    3rd trimester

    supine hypotension syndrone. hypersensitive gag reflex.

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    Up right PositionUp right Position

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    Drugs In PregnancyDrugs In Pregnancy

    SafeSafe

    Antibiotic.

    -Penicillin.-Cephalosporin.

    -Climdamycin.

    UnsafeUnsafe

    Erythromycine

    - Hepato toxicTetragcycline-Staining,Hypoplasia

    Metronidazole-CleftAminoglycosides- Otonephrotoxicity

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    AnalgesicAnalgesic

    Paracetamol :Paracetamol : Asprin:- ClettNSAID- Close

    ductus .Pulmonary HTV

    Local Anasthesia:Local Anasthesia: Pilocarpine:Lido caine

    MethemoglobenemiaBupivacaine Felypressin

    Contracture

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    Oral Contraceptive PillsOral Contraceptive Pills

    Sex steroids. risk of MI +

    Thromboemboli. risk of dry socket. Ab effect

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    LactationLactation

    Not Pass withNot Pass with

    MilkMilk

    - Mefenaic acid.

    -Paracetamol.- Penicilline.

    - Erythromycine.- Cephalexin.

    -Drug excreted inbreast milk is 1% ofmaternal dose- Avoid tetracyclin.

    - Mother take drug +avoid breast feedingfor 4 hours.

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    Preganacy + X-rayPreganacy + X-ray

    -Daily background radiation is 4rad.

    1000

    -Full Mouth X-ray 1 rad100. 000

    - Genetic damage : 10 rad

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    Oral ComplicationOral Complication

    Pregnancy Tumor:

    - Its an exaggerated localized

    inflammatory hyperplasic tissuesresponse.

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    Calcium in teeth + Pregnancy.

    A tooth for every pregnancy

    Ca is found in crystalline form in

    teeth + its resorbed from bone notfrom teeth.

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    AsthmaAsthma

    Syndrome : dyspneaCough

    bronchospasm

    WheezeIntrimsic - ve family hx

    adult

    Extrinsic - Allergenchildren

    +ve family hx

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    BronchospasmBronchospasm

    is due to: 1) thick basement memb of

    bronchide.

    2) Mucous.3) Edema4) Hypertrophy of Muscle.

    Ocluded bronchiole.

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    How to manage dental asthmaticHow to manage dental asthmatic

    ptpt

    -Good hx. : identify Pt

    - Avoid precipitaing factor pt bring hismedication.- Avoid anxeity diazepan given beforeprocedure.

    - Avoid : AsprinNSAIDPenicillinSulfites (preservative in L. A)

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    - Give prophylactic B2 against salbutamol

    - Morning visit.

    Inemergency:Give salbutamol bronchodilator. Pt up; be calm. Give oxygen 10l/ min. Salbutamol / 2 mints.

    Hydrocortisone 2oo mg 1.v

    Be careful of status asmaticus = persistentattack not resolved by medication: fatacl

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    CandidaCandida

    Due to cortisone in haler

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    HEMLICH

    MANEUVER

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    Hysteric anexiety

    Hyperventilation

    Alkalosis

    Loss of consciousAction:Pt should breath thru bag

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    diabeticdiabetic

    Is a chronic metabolic disorder characterizedby relative or absolute lack of insulin.

    B cells Pancreas Insulin

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    Dx of DMDx of DM

    1)Fasting venous blood sugur 7mmol/ L 125 mg/d l2)2 hours oral glucose tolerance test

    > 11.1 mmol/ L210 mg/ dl

    3) Plasma glycosylated Hb Hb A1c > 7%

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    InsulinInsulin

    +protein synlhesis.+ glycogenesis.

    + lipogenesis.-glygogeolysis.- proteolysis.

    - gluconeogenesis.

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    Give early morning visits with pt. taking his meal dx IHD + Renal F

    Postural hypotension due to autonomic heuwp .

    Metformin (glucophage)

    should be stopped in Diabetic pt. to prevent nepnrotoxicity.

    Restant Metformin restantail 2-3 days.

    Suscoptability to infection + delayed wound heafing.

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    -Leucocytes dysfunction DM is eqivocal

    - Implant success rate 86% 96%

    No contraindication to implant but give Ab.

    Metformin stopped by i.v contrast

    nephrotoxicity (Glugophage)

    Give L. A e epinephrine no C. I

    Asprin NSAID enhance OHD. Amoxycillin + Acetamenophen is best given.

    No relation with bleeding

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    Features of DMFeatures of DM

    -Polyuria-Polydypsia-Polyphagia

    -Thirst-Wt loss-Weakness-confusion

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    Problem of DMProblem of DM

    Glucose intolerance

    Fat breakdown F. acids

    Acetone (bad breath) Metabolic Acidosis Ketonebodies

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    Management of DMManagement of DM

    Poor Controlled DM > 250 mg/ dlDefer until controlled in emergency : do surgery but giveprophylactic

    Ab

    -DM + on Diet + controlled No precausion

    -DM on oral hypoglycemic controlled no precausia- If uncontrolled stop oral hypog. start insulin

    check glucose / 2h(stabilize lucose by insulin)

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    EmergencyEmergency

    Always give glucose if pt. is conscious + dont giveInsulin b/ c hypoglycemic.Hypoglycemic Diabetic

    Hyporglycemic comicSweaty dehudrared

    Bounding pulse weak pulseRapid anset slow onsetLoss of conscious acetone breathConvulsions vomiting

    Give glucose give insulin+ K+

    Or glucagon (.mg

    Hypoglycemia is more fatal chan hyperglycemia.

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    HypoglycemiaHypoglycemia

    Give oral glucose if pt. can. If Pt. drowsy sublingual glucogel Put i.v line if you can. If put Unconscious gluagon 1mg 1.m

    + repeat / 2-3 min+ call for amulance

    start CPR.

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    HypertensionHypertension

    Persistent raised B. p > 140/90Bp controlled by out put + vascular

    resistanceBp e age + in morning + night

    Bp measured in relaxed situation.

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    Antihypertensive drugsAntihypertensive drugs

    Xerostomia

    Gingival swelling.

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    Categories of HT N HTNCategories of HT N HTN

    Hypertensive emergency 210/ 120 end organfailure.Hypertensive urgency no end organ failure.Mild uncomplicated.

    Transient Hypertensive episode.

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    HTN EtiologyHTN Etiology

    Essential 2 nd HTN90% casesObesity pregnancy

    SmokingcontracetivepillsGenetics endocrineFamilial

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    Pain perception in hypertensive pt. is less than

    normal pt. why?!Not known

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    Features of HypertensiveFeatures of Hypertensive

    Headache Dizziness. Tinnitus Angina

    vision disturbance protein hematuria

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    ClassificationClassification

    ASAI < 140/190 II 140-160/ 90-100 III 160-180/ 95-110

    IV > 180 / > 110

    Routine workcheck Bprestrict epinephrinecontrol Bp

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    ManagementManagement

    Consult physician Temazepan 10 mgprop. check Bp If elvated 40 mg furisomtle captopril 2Img

    Give L.A with adrenaline expect in 200/120 Late morning visits why? postural hypo tensive, why?

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    Inadequate O2

    for myocardium

    causes:- Altheroma + narrawing of coronary Vs

    - DM HTN LDL

    - Lack of exercise smoking.Signs:- breathlessness 50B- Chest Pain : need morphine.

    ttt

    -B blocker. - Subblingual nitrate.- Ca channel blocker.- stenting, Angioplasty- GABG

    IHDIHD

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    Not all angina painful. Silent Angina diabetic pt.

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    1) Avoid stressful events.2) Be brief with short visits.3) Give all the Rx medication even the

    Anticoagulant.4) Avoid painful events with good L. A. +

    Long acting agents.

    How to manageHow to manage?!?!

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    Best local anasthetic is mepivacaiene?

    Give preop temazepam

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    Give preop temazepam. diazepam 10 mg.

    G. A is contraindication for MI pt until 9 month.

    - Diuretics so short session.- Antihypertensive Postural hypotensia.

    raise him slowly. Dry mouth

    -Bleeding tendency due to Auticaoagulant.

    - Ca channel blocker giwgiual swelling.- 2 puffs of subbing Nitroglycirne before ttforstable Angina pt.

    -Instable Angina best to avoid. risk of MI

    - MI delay > 6 mo.Pacemakers:

    -Avoid: - Ultrasanic Scaler - MRI - Lithotripsy - U/

    E i h i ?!

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    Epinephrine?!Max does of epinephrine for O Pt. according to AHAis 0.04 mg.

    Endogenous epinephrine released by body is higherthan the amount in L. A + is more dangerous.So, Give L. A e long acting agent i.e. bupivacaine +epinephrine.

    [ ] < 1 : 100.000I g : 100.000 ml .01 X 1.41000 mg 100.000 mlI mg : 100 ml0.0 lmg : ml

    ? : 1.8 ml (Cartidges).? = 1.8 ml X 0.0 lmg

    ml0.018 mg

    0.04mg / 0.018 mh = 2 cartridges in each session

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    -Infection of Endocardium by bacteria whereturbulence is found.

    -Infection vegetation + emboli.- Turbulence = Cardiac Lesion.

    - dental ext = I. E in 1/3000 pt.- Bacteria : Strepto. Viridins.

    whymultiple attachment Ability to multiply rapidly.

    - Indrug addict: staph (skin)-

    Infective Endocardits IEInfective Endocardits IE

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    - Occur 3-4 weeks after surgical procedure.-Low fewer malaise.- Anemia , joint pain- infarct due to emboli micro emboli.

    - Kidney heat emboli hematuria.- Stroke.- If not tt 30% fatal.- Murmurs.- Echo ECG- Osters nodules.- Tender skin vasculitis.

    Clinical Features of I. EClinical Features of I. E

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    Factors of I. EFactors of I. E

    -No3 of Bacteria.

    - Host factors.

    - congental O dis.- Ab.- Adherence to endocardium

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    Mainly I. EMainly I. EOld Age > 60

    Mitral valve 40%Rare in child.

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    Chance of I. EChance of I. E

    dentaldental

    Extraction : 1/3000Extraction : 1/3000

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    - Admission- ECG.- Echo Cardio gram.- 3 Blood culture if hr interval.- 2-3 week of Ab Amoxycillin + gentamycin.- Replace infected valve.

    Management of IEManagement of IE

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    Dont give Ab. For low riskDont give Ab. For low risk

    people or low risk procedurespeople or low risk proceduresProcedure

    s

    NeedEndo beyond apexSialographyRubberSubgingprocedures

    CordsScaling

    ExtIntroligamentalinjMatrix bandtwedge

    No NeedStich removedXrayExfoliation ofdecide

    Endo not beyond

    apex impressiaI + D

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    Risks GroupsRisks Groups

    High Intermediate Low

    Prosthetic Ov. I ASD GABB

    Previous I. E VSD 6m Mitral valve

    Mitral v.

    prolopsse

    Downs sy. Pulm. Stenisis

    MI

    Bl di Di d

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    Bleeding Disorders:

    Hemophilia A

    X-linked spontaneous bleeding. bleeding after stops procedure but clot dissociated+ pressure. Will not resume clotting.

    Interenal bleeding, hemarthrosis, joint deformity. petectes.

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    Classification:

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    Classification:

    Depends on level of 8 in blood

    One unit/ One ml.

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    < One Unit : / one ml severerspontaneaus.1-5 unit/ one ml bleeding from moderate traume.> 5 unit/ one ml major traumer

    cause bleeding

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    Bleeding Time: NormalProlhrombin T : normal

    Partial lhromboplastic Time: prolonged.

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    Management- Give replacement therapy factor 8 TT iv +

    Hcn- Decompression : intransal spray.

    1.5 mg/ ml 0.1 ml0.3 0.5 mg/ kg

    Deamino 8 D arginine vasopressin (D8DAVP)

    -Tranexamic acid (lysine) Not approved by FDA lg/ orally x 4

    10mg/ kg 1.v30mg/ kg oral

    Antifrbrynolytic thrombosis episodes. topical 5% m/w.