In the article, “Host and Viral Factors Affecting Clinical Performance of a Rapid Diagnostic Test for Respiratory Syncytial Virus in Hospitalized Children,” by Papenburg et al, J Pediatr 2013;163:911-3, the authors inadvertently provided the incorrect negative likelihood ratio in the last sentence of the second paragraph of the Results section. The corrected sentence is: Positive and negative likelihood ratios were 25.7 (95% CI, 13.0-50.9) and 0.21 (95% CI, 0.17-0.25), respectively. In the article, “Low Morbidity and Mortality in Children with Diabetic Ketoacidosis Treated with Isotonic Fluids,” by White and Dickson, J Pediatr 2013;163:761-6, Table II contained misaligned data and Table III included incorrect data for K, mEq. The corrected versions Tables II and III are below. Table II. Outcomes Dallas (present study) US 2 UK 3 Definition of DKA ICD-9 codes ICD-9 codes zz Physician reports; pH<7.3 or bicarbonate <18 mmol/l or heavy ketonuria Definition of cerebral edema DKA AND altered mental status AND [radiographic evidence of cerebral edema OR specific treatment (hyperosmolar therapy or intubation)] Blood glucose >300 AND [pH <7.25 OR bicarbonate <15 mmol/L ] AND altered mental status AND [radiographic or pathologic evidence of cerebral edema OR specific treatment (hyperosmolar therapy or hyperventilation) followed by clinical improvement] Deterioration in level of consciousness AND $1 of: Hypertension, bradycardia, pupillary changes, ophthalmoplegia, papilledema, respiratory arrest, decerebrate or decorticate posturing, OR radiologic evidence of moderate or severe cerebral edema Total No. of DKA cases 3712 6977 2940 Total No. of cerebral edema cases (%) 20 (0.5)* ,† 61 (0.9)* 20 (0.7) z , 34 x 13 (0.3) †,z Patients presenting > 7 h (%) 2 (0.06) {, ** 30 (0.4) { 10 (0.3)** Mild-moderate neurologic disability, No. 2 8 9 x Severe neurologic disability, No. 0 4 Death, No. 1 13 8 x Total death and disability, No. (%) 3 (0.08) †† 25 (0.3) †† *P = .06 (for the comparison between the two quantities bearing this symbol). †The 2 figures for the Dallas data use definitions of cerebral edema as similar as possible to the US and UK studies, respectively. zP = .06. xCerebral edema cases were oversampled, and death and disability data are available only for the oversampled total. {P = .0007. **P = .006. ††P = .008. zzThe US study required pH <7.25 for subjects included in a nested case-control study. Table III. Comparison of fluid volumes and electrolytes specified by different protocols for a hypothetical 30 kg, 1-m 2 patient Time, h Children’s Medical Center Dallas ADA 2006 consensus 5 % NaCl Rate, mL/h Volume, mL Na, mEq K, mEq % NaCl Rate, mL/h Volume, mL Na, mEq K, mEq 0-1 0.9 600 600 92 0 0.9 300 300 46 0 1-4 0.675 155 465 54 23 0.9 125 375 58 18 4-24 0.675 155 3100 358 152 0.45 125 2500 193 123 Mean [cation], mEq/L 155 130 24-h totals 4165 504 175 3175 297 141 927

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In the article, “Low Morbidity and Mortality in Children with Diabetic Ketoacidosis Treated with Isotonic Fluids,” by White

and Dickson, J Pediatr 2013;163:761-6, Table II contained misaligned data and Table III included incorrect data for K, mEq.The corrected versions Tables II and III are below.

Table II. Outcomes

Dallas (present study) US2 UK3

Definition of DKA ICD-9 codes ICD-9 codeszz Physician reports;pH<7.3 or bicarbonate <18 mmol/l or heavyketonuria

Definition of cerebral edema DKA AND altered mentalstatus AND [radiographicevidence of cerebraledema OR specifictreatment (hyperosmolartherapy or intubation)]

Blood glucose >300 AND [pH <7.25OR bicarbonate <15 mmol/L ]AND altered mental status AND[radiographic or pathologic evidenceof cerebral edema OR specifictreatment (hyperosmolar therapy orhyperventilation) followed by clinicalimprovement]

Deterioration in level of consciousness AND $1 of:Hypertension, bradycardia, pupillary changes,ophthalmoplegia, papilledema, respiratoryarrest, decerebrate or decorticate posturing,OR radiologic evidence of moderate or severecerebral edema

Total No. of DKA cases 3712 6977 2940Total No. of cerebral edemacases (%)

20 (0.5)*,† 61 (0.9)* 20 (0.7)z, 34x

13 (0.3)†,z

Patients presenting > 7 h (%) 2 (0.06){,** 30 (0.4){ 10 (0.3)**Mild-moderate neurologic

disability, No.2 8 9x

Severe neurologic disability, No. 0 4Death, No. 1 13 8x

Total death and disability,No. (%)

3 (0.08)†† 25 (0.3)††

*P = .06 (for the comparison between the two quantities bearing this symbol).†The 2 figures for the Dallas data use definitions of cerebral edema as similar as possible to the US and UK studies, respectively.zP = .06.xCerebral edema cases were oversampled, and death and disability data are available only for the oversampled total.{P = .0007.**P = .006.††P = .008.zzThe US study required pH <7.25 for subjects included in a nested case-control study.

Table III. Comparison of fluid volumes and electrolytes specified by different protocols for a hypothetical 30 kg, 1-m2

patient

Time, h

Children’s Medical Center Dallas ADA 2006 consensus5

% NaCl Rate, mL/h Volume, mL Na, mEq K, mEq % NaCl Rate, mL/h Volume, mL Na, mEq K, mEq

0-1 0.9 600 600 92 0 0.9 300 300 46 01-4 0.675 155 465 54 23 0.9 125 375 58 184-24 0.675 155 3100 358 152 0.45 125 2500 193 123Mean [cation], mEq/L 155 13024-h totals 4165 504 175 3175 297 141

927