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covid19.healthdata.org 1 Institute for Health Metrics and Evaluation COVID-19 Results Briefing The South-East Asia Region February 20, 2021 This document contains summary information on the latest projections from the IHME model on COVID-19 in the South-East Asia Region. The model was run on February 20, 2021, with data through February 16, 2021. Daily cases continued to decline, while daily deaths increased slightly across the South- East Asia Region. There are two primary drivers for the declining trend in cases: 1) scaled- up vaccination, and, more importantly, 2) seasonality, which peaked at the end of January and is now declining. However, as transmission is declining in most locations across the region, India has localized spikes in transmission, notably in the state of Maharashtra. Two factors are contributing to local increases in transmission and could in some countries lead to larger surges: 1) the steady spread of variants B.1.1.7 and B.1.351, and 2) the public’s behavioral response to the positive trends. We expect an additional 57,000 deaths within the region between now and June 1 in the reference scenario. Reductions in mask wearing and social distancing can, combined with new variant spread, lead to spring surges. Our reference scenario does not include these surges, but the way in which behavior changes after mandates are lifted and vaccines are administered will have a critical impact. Looking past June 1, reduced efficacy of vaccines against variants B.1.351 and P.1, combined with the possibility that there may not be cross-variant immunity, makes achieving herd immunity unlikely prior to next winter. Current situation Daily reported cases in the last week decreased to 21,800 per day on average compared to 25,200 the week before (Figure 1). Daily deaths in the last week increased to 440 per day on average compared to 430 the week before (Figure 2). This makes COVID-19 the number 18 cause of death in the South-East Asia Region this week (Table 1). Effective R, computed using cases, hospitalizations, and deaths, is greater than 1 in three locations – the Indian states of Maharashtra, Nagaland, and Mizoram (Figure 5). We estimated that 9% of people in the South-East Asia Region have been infected as of February 16 (Figure 4). No locations in the region had daily death rates greater than 4 per million (Figure 3). Trends in drivers of transmission Mobility last week was 21% lower than the pre-COVID-19 baseline (Figure 7). Mobility was near baseline (within 10%) in Bangladesh and Nepal. Mobility was lower than 30% of baseline in Myanmar and Sri Lanka.

COVID-19 Results Briefing€¦ · The South-East Asia Region February 20, 2021 This document contains summary information on the latest projections from the IHME model on COVID-19

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Page 1: COVID-19 Results Briefing€¦ · The South-East Asia Region February 20, 2021 This document contains summary information on the latest projections from the IHME model on COVID-19

covid19.healthdata.org 1 Institute for Health Metrics and Evaluation

COVID-19 Results Briefing

The South-East Asia Region

February 20, 2021 This document contains summary information on the latest projections from the IHME model on COVID-19 in the South-East Asia Region. The model was run on February 20, 2021, with data through February 16, 2021.

Daily cases continued to decline, while daily deaths increased slightly across the South-East Asia Region. There are two primary drivers for the declining trend in cases: 1) scaled-up vaccination, and, more importantly, 2) seasonality, which peaked at the end of January and is now declining. However, as transmission is declining in most locations across the region, India has localized spikes in transmission, notably in the state of Maharashtra. Two factors are contributing to local increases in transmission and could in some countries lead to larger surges: 1) the steady spread of variants B.1.1.7 and B.1.351, and 2) the public’s behavioral response to the positive trends. We expect an additional 57,000 deaths within the region between now and June 1 in the reference scenario. Reductions in mask wearing and social distancing can, combined with new variant spread, lead to spring surges. Our reference scenario does not include these surges, but the way in which behavior changes after mandates are lifted and vaccines are administered will have a critical impact. Looking past June 1, reduced efficacy of vaccines against variants B.1.351 and P.1, combined with the possibility that there may not be cross-variant immunity, makes achieving herd immunity unlikely prior to next winter.

Current situation • Daily reported cases in the last week decreased to 21,800 per day on average compared

to 25,200 the week before (Figure 1).

• Daily deaths in the last week increased to 440 per day on average compared to 430 the week before (Figure 2). This makes COVID-19 the number 18 cause of death in the South-East Asia Region this week (Table 1).

• Effective R, computed using cases, hospitalizations, and deaths, is greater than 1 in three locations – the Indian states of Maharashtra, Nagaland, and Mizoram (Figure 5).

• We estimated that 9% of people in the South-East Asia Region have been infected as of February 16 (Figure 4).

• No locations in the region had daily death rates greater than 4 per million (Figure 3).

Trends in drivers of transmission • Mobility last week was 21% lower than the pre-COVID-19 baseline (Figure 7). Mobility

was near baseline (within 10%) in Bangladesh and Nepal. Mobility was lower than 30% of baseline in Myanmar and Sri Lanka.

Page 2: COVID-19 Results Briefing€¦ · The South-East Asia Region February 20, 2021 This document contains summary information on the latest projections from the IHME model on COVID-19

covid19.healthdata.org 2 Institute for Health Metrics and Evaluation

• As of February 16, we estimated that 66% of people always wore a mask when leaving their home (Figure 9), the same as last week. Mask use was lower than 50% in Assam, India.

• There were 46 diagnostic tests per 100,000 people on February 16 (Figure 11).

• In the South-East Asia Region, 72.3% of people say they would accept or would probably accept a vaccine for COVID-19. The fraction of the population who are open to receiving a COVID-19 vaccine ranges from 67% in Bangladesh to 81% in Myanmar (Figure 14).

• In our current reference scenario, we expect that 444.55 million will be vaccinated by June 1 (Figure 15).

Projections • In our reference scenario, which represents what we think is most likely to happen,

our model projects 415,000 cumulative deaths on June 1, 2021. This represents 53,000 additional deaths from February 16 to June 1 (Figure 16). With mobility and variant spread increasing, a spring surge will bring daily deaths back up to 710 by June 1, 2021 (Figure 17).

• By June 1, 2021, we project that 3,700 lives will be saved by the projected vaccine rollout.

• If universal mask coverage (95%) were attained in the next week, our model projects 16,000 fewer cumulative deaths compared to the reference scenario on June 1, 2021 (Figure 16).

• Under our worse scenario, our model projects 424,000 cumulative deaths on June 1, 2021 (Figure 16).

• Figure 19 compares our reference scenario forecasts to other publicly archived models. Forecasts are widely divergent.

• At some point from February through June 1, three countries will have high or extreme stress on hospital beds (Figure 22). At some point from February through June 1, four countries will have high or extreme stress on ICU capacity (Figure 21).

Page 3: COVID-19 Results Briefing€¦ · The South-East Asia Region February 20, 2021 This document contains summary information on the latest projections from the IHME model on COVID-19

South-East Asia Region COVID-19 RESULTS BRIEFING

Model updatesWe have updated our model that predicts the spread of the new variants, which is used in the referencescenario in two ways. First, the speed of scale-up of the new variants is now based on data from more than15 locations, whereas previously we only had data from London. Second, we now use observed data on thepresence of new variants (B.1.1.7, B.1.351, or P1) in all locations with reported community transmission andmore than five cases of those variants sequenced.

covid19.healthdata.org 2 Institute for Health Metrics and Evaluation

Page 4: COVID-19 Results Briefing€¦ · The South-East Asia Region February 20, 2021 This document contains summary information on the latest projections from the IHME model on COVID-19

South-East Asia Region COVID-19 RESULTS BRIEFING

Figure 1. Reported daily COVID-19 cases

0

25,000

50,000

75,000

100,000

Feb 20 Mar 20 Apr 20 May 20 Jun 20 Jul 20 Aug 20 Sep 20 Oct 20 Nov 20 Dec 20 Jan 21 Feb 21 Mar 21Month

Cou

nt

Daily cases

Table 1. Ranking of COVID-19 among the leading causes of mortality this week, assuming uniform deathsof non-COVID causes throughout the year

Cause name Weekly deaths RankingIschemic heart disease 39,868 1Stroke 27,102 2Chronic obstructive pulmonary disease 21,984 3Diarrheal diseases 14,328 4Lower respiratory infections 11,327 5Tuberculosis 10,815 6Neonatal disorders 10,504 7Diabetes mellitus 9,152 8Cirrhosis and other chronic liver diseases 8,514 9Chronic kidney disease 6,390 10COVID-19 3,099 18

covid19.healthdata.org 3 Institute for Health Metrics and Evaluation

Page 5: COVID-19 Results Briefing€¦ · The South-East Asia Region February 20, 2021 This document contains summary information on the latest projections from the IHME model on COVID-19

South-East Asia Region COVID-19 RESULTS BRIEFING

Figure 2. Reported daily COVID-19 deaths

0

1,000

2,000

Jan 20 Feb 20 Mar 20 Apr 20 May 20 Jun 20 Jul 20 Aug 20 Sep 20 Oct 20 Nov 20 Dec 20 Jan 21 Feb 21 Mar 21

Dai

ly d

eath

s

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Page 6: COVID-19 Results Briefing€¦ · The South-East Asia Region February 20, 2021 This document contains summary information on the latest projections from the IHME model on COVID-19

South-East Asia Region COVID-19 RESULTS BRIEFING

Figure 3. Daily COVID-19 death rate per 1 million on February 16, 2021

<1

1 to 1.9

2 to 2.9

3 to 3.9

4 to 4.9

5 to 5.9

6 to 6.9

7 to 7.9

>=8

Figure 4. Estimated percent of the population infected with COVID-19 on February 16, 2021

<5

5−9.9

10−14.9

15−19.9

20−24.9

25−29.9

30−34.9

35−39.9

>=40

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Page 7: COVID-19 Results Briefing€¦ · The South-East Asia Region February 20, 2021 This document contains summary information on the latest projections from the IHME model on COVID-19

South-East Asia Region COVID-19 RESULTS BRIEFING

Figure 5. Mean effective R on February 05, 2021. The estimate of effective R is based on the combinedanalysis of deaths, case reporting, and hospitalizations where available. Current reported cases reflectinfections 11-13 days prior, so estimates of effective R can only be made for the recent past. Effective R lessthan 1 means that transmission should decline, all other things being held the same.

<0.65

0.65−0.73

0.74−0.82

0.83−0.9

0.91−0.99

1−1.08

1.09−1.16

1.17−1.25

1.26−1.34

>=1.35

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Page 8: COVID-19 Results Briefing€¦ · The South-East Asia Region February 20, 2021 This document contains summary information on the latest projections from the IHME model on COVID-19

South-East Asia Region COVID-19 RESULTS BRIEFING

Figure 6. Percent of COVID-19 infections detected. This is estimated as the ratio of reported dailyCOVID-19 cases to estimated daily COVID-19 infections based on the SEIR disease transmission model.

0%

25%

50%

75%

100%

Apr 20 May 20 Jun 20 Jul 20 Aug 20 Sep 20 Oct 20 Nov 20 Dec 20 Jan 21 Feb 21 Mar 21

Per

cent

of i

nfec

tions

det

ecte

d

African Region

Region of the Americas

South−East Asia Region

European Region

Eastern Mediterranean Region

Western Pacific Region

*Due to measurement errors in cases and testing rates, the infection to detection rate (IDR) can exceed 100% at particular points in time.

covid19.healthdata.org 7 Institute for Health Metrics and Evaluation

Page 9: COVID-19 Results Briefing€¦ · The South-East Asia Region February 20, 2021 This document contains summary information on the latest projections from the IHME model on COVID-19

South-East Asia Region CRITICAL DRIVERS

Critical driversTable 2. Current mandate implementation

All

none

ssen

tial b

usin

esse

s cl

osed

Any

bus

ines

ses

rest

ricte

d

Any

gat

herin

gs r

estr

icte

d

Mas

k us

e

Sch

ool c

losu

re

Sta

y ho

me

orde

r

Trav

el li

mits

Timor−LesteThailand

Sri LankaNepal

MyanmarMaldives

IndonesiaIndia

Democratic People's Republic of KoreaBhutan

Bangladesh

Mandate in place

Mandate in place (imposed this week)

No mandate

No mandate (lifted this week)

*Not all locations are measured at the subnational level.

covid19.healthdata.org 8 Institute for Health Metrics and Evaluation

Page 10: COVID-19 Results Briefing€¦ · The South-East Asia Region February 20, 2021 This document contains summary information on the latest projections from the IHME model on COVID-19

South-East Asia Region CRITICAL DRIVERS

Figure 7. Trend in mobility as measured through smartphone app use compared to January 2020 baseline

−50

−25

0

Jan 20 Feb 20 Mar 20 Apr 20 May 20 Jun 20 Jul 20 Aug 20 Sep 20 Oct 20 Nov 20 Dec 20 Jan 21 Feb 21Mar 21

Per

cent

red

uctio

n fr

om a

vera

ge m

obili

ty

African Region

Region of the Americas

South−East Asia Region

European Region

Eastern Mediterranean Region

Western Pacific Region

Figure 8. Mobility level as measured through smartphone app use compared to January 2020 baseline(percent) on February 16, 2021

=<−50

−49 to −45

−44 to −40

−39 to −35

−34 to −30

−29 to −25

−24 to −20

−19 to −15

−14 to −10

>−10

covid19.healthdata.org 9 Institute for Health Metrics and Evaluation

Page 11: COVID-19 Results Briefing€¦ · The South-East Asia Region February 20, 2021 This document contains summary information on the latest projections from the IHME model on COVID-19

South-East Asia Region CRITICAL DRIVERS

Figure 9. Trend in the proportion of the population reporting always wearing a mask when leaving home

0

25

50

75

Jan 20 Feb 20 Mar 20 Apr 20 May 20 Jun 20 Jul 20 Aug 20 Sep 20 Oct 20 Nov 20 Dec 20 Jan 21 Feb 21Mar 21

Per

cent

of p

opul

atio

n

African Region

Region of the Americas

South−East Asia Region

European Region

Eastern Mediterranean Region

Western Pacific Region

Figure 10. Proportion of the population reporting always wearing a mask when leaving home on February16, 2021

<30%

30 to 34%

35 to 39%

40 to 44%

45 to 49%

50 to 54%

55 to 59%

60 to 64%

65 to 69%

>=70%

covid19.healthdata.org 10 Institute for Health Metrics and Evaluation

Page 12: COVID-19 Results Briefing€¦ · The South-East Asia Region February 20, 2021 This document contains summary information on the latest projections from the IHME model on COVID-19

South-East Asia Region CRITICAL DRIVERS

Figure 11. Trend in COVID-19 diagnostic tests per 100,000 people

0

100

200

Jan 20 Feb 20 Mar 20 Apr 20 May 20 Jun 20 Jul 20 Aug 20 Sep 20 Oct 20 Nov 20 Dec 20 Jan 21 Feb 21Mar 21

Test

per

100

,000

pop

ulat

ion

African Region

Region of the Americas

South−East Asia Region

European Region

Eastern Mediterranean Region

Western Pacific Region

Figure 12. COVID-19 diagnostic tests per 100,000 people on February 12, 2021

<5

5 to 9.9

10 to 24.9

25 to 49

50 to 149

150 to 249

250 to 349

350 to 449

450 to 499

>=500

covid19.healthdata.org 11 Institute for Health Metrics and Evaluation

Page 13: COVID-19 Results Briefing€¦ · The South-East Asia Region February 20, 2021 This document contains summary information on the latest projections from the IHME model on COVID-19

South-East Asia Region CRITICAL DRIVERS

Figure 13 Increase in the risk of death due to pneumonia on February 1 2020 compared to August 1 2020

<−80%

−80 to −61%

−60 to −41%

−40 to −21%

−20 to −1%

0 to 19%

20 to 39%

40 to 59%

60 to 79%

>=80%

covid19.healthdata.org 12 Institute for Health Metrics and Evaluation

Page 14: COVID-19 Results Briefing€¦ · The South-East Asia Region February 20, 2021 This document contains summary information on the latest projections from the IHME model on COVID-19

South-East Asia Region CRITICAL DRIVERS

Figure 14. This figure shows the estimated proportion of the adult (18+) population that is open toreceiving a COVID-19 vaccine based on Facebook survey responses (yes and yes, probably).

<50%

50−59%

60−69%

70−74%

75−79%

80−84%

>85%

Figure 15. The number of people who receive any vaccine and those who are effectively vaccinated andprotected against disease, accounting for efficacy, loss to follow up for two-dose vaccines, partial immunityafter one dose, and immunity after two doses.

0

300,000,000

600,000,000

900,000,000

0

10

20

30

40

Dec 2

0

Jan

21

Feb

21

Mar

21

Apr 2

1

May

21

Jun

21

Peo

ple

Percent of adult population

Reference rollout Rapid rollout

Solid lines represent the total vaccine doses, dashed lines represent effective vaccination

covid19.healthdata.org 13 Institute for Health Metrics and Evaluation

Page 15: COVID-19 Results Briefing€¦ · The South-East Asia Region February 20, 2021 This document contains summary information on the latest projections from the IHME model on COVID-19

South-East Asia Region PROJECTIONS AND SCENARIOS

Projections and scenariosWe produce three scenarios when projecting COVID-19. The reference scenario is our forecast of what wethink is most likely to happen:

• Vaccines are distributed at the expected pace.• Governments adapt their response by re-imposing social distancing mandates for 6 weeks whenever

daily deaths reach 8 per million, unless a location has already spent at least 7 of the last 14 dayswith daily deaths above this rate and not yet re-imposed social distancing mandates. In this case, thescenario assumes that mandates are re-imposed when daily deaths reach 15 per million.

• Variants B.1.1.7 (first identified in the UK), B.1.351 (first identified in South Africa), and P1 (firstidentified in Brazil) continue to spread from locations with (a) more than 5 sequenced variants, and(b) reports of community transmission, to adjacent locations following the speed of variant scale-upobserved in the regions of the UK.

• In one-quarter of those vaccinated, mobility increases toward pre-COVID-19 levels.

The worse scenario modifies the reference scenario assumptions in two ways:

• First, it assumes that variants B.1.351 or P1 begin to spread within 2 weeks in all locations that do notalready have B.1.351 or P1 community transmission.

• Second, it also assumes that all those vaccinated increase their mobility toward pre-COVID-19 levels.

The universal masks scenario makes all the same assumptions as the reference scenario but also assumes95% of the population wear masks in public in every location.

covid19.healthdata.org 14 Institute for Health Metrics and Evaluation

Page 16: COVID-19 Results Briefing€¦ · The South-East Asia Region February 20, 2021 This document contains summary information on the latest projections from the IHME model on COVID-19

South-East Asia Region PROJECTIONS AND SCENARIOS

Figure 16. Cumulative COVID-19 deaths until June 01, 2021 for three scenarios

0

100,000

200,000

300,000

400,000

0

5

10

15

20

Oct 20 Nov 20 Dec 20 Jan 21 Feb 21 Mar 21 Apr 21 May 21 Jun 21

Cum

ulat

ive

deat

hsC

umulative deaths per 100,000

Reference scenario

Universal mask use

Worse

Figure 17. Daily COVID-19 deaths until June 01, 2021 for three scenarios

0

500

1,000

1,500

2,000

2,500

0.00

0.04

0.08

0.12

Feb 20 Apr 20 Jun 20 Aug 20 Oct 20 Dec 20 Feb 21 Apr 21 Jun 21

Dai

ly d

eath

sD

aily deaths per 100,000

Reference scenario

Universal mask use

Worse

covid19.healthdata.org 15 Institute for Health Metrics and Evaluation

Page 17: COVID-19 Results Briefing€¦ · The South-East Asia Region February 20, 2021 This document contains summary information on the latest projections from the IHME model on COVID-19

South-East Asia Region PROJECTIONS AND SCENARIOS

Figure 18. Daily COVID-19 infections until June 01, 2021 for three scenarios

0

250,000

500,000

750,000

1,000,000

1,250,000

0

20

40

60

Feb 20 Apr 20 Jun 20 Aug 20 Oct 20 Dec 20 Feb 21 Apr 21 Jun 21

Dai

ly in

fect

ions

Daily infections per 100,000

Reference scenario

Universal mask use

Worse

Figure 23. Forecasted percent infected with COVID-19 on June 01, 2021

<5

5−9.9

10−14.9

15−19.9

20−24.9

25−29.9

30−34.9

35−39.9

>=40

covid19.healthdata.org 16 Institute for Health Metrics and Evaluation

Page 18: COVID-19 Results Briefing€¦ · The South-East Asia Region February 20, 2021 This document contains summary information on the latest projections from the IHME model on COVID-19

South-East Asia Region PROJECTIONS AND SCENARIOS

Figure 19. Comparison of reference model projections with other COVID modeling groups. For thiscomparison, we are including projections of daily COVID-19 deaths from other modeling groups when available:Delphi from the Massachussets Institute of Technology (Delphi; https://www.covidanalytics.io/home),Imperial College London (Imperial; https://www.covidsim.org), The Los Alamos National Laboratory (LANL;https://covid-19.bsvgateway.org/), and the SI-KJalpha model from the University of Southern California(SIKJalpha; https://github.com/scc-usc/ReCOVER-COVID-19). Daily deaths from other modeling groupsare smoothed to remove inconsistencies with rounding. Regional values are aggregates from availble locationsin that region.

0

200

400

600

Mar 21 Apr 21 May 21 Jun 21Date

Dai

ly d

eath

s

Models

IHME

Delphi

Imperial

LANL

SIKJalpha

covid19.healthdata.org 17 Institute for Health Metrics and Evaluation

Page 19: COVID-19 Results Briefing€¦ · The South-East Asia Region February 20, 2021 This document contains summary information on the latest projections from the IHME model on COVID-19

South-East Asia Region PROJECTIONS AND SCENARIOS

Figure 20. The estimated inpatient hospital usage is shown over time. The percent of hospital beds occupiedby COVID-19 patients is color coded based on observed quantiles of the maximum proportion of beds occupiedby COVID-19 patients. Less than 5% is considered low stress, 5-9% is considered moderate stress, 10-19% isconsidered high stress, and greater than 20% is considered extreme stress.

Thailand

Sri Lanka

Nepal

Myanmar

Maldives

Indonesia

India

Bangladesh

Apr 20 Jun 20 Aug 20 Oct 20 Dec 20 Feb 21 Apr 21 Jun 21

Stress level

Low

Moderate

High

Extreme

All hospital beds

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Page 20: COVID-19 Results Briefing€¦ · The South-East Asia Region February 20, 2021 This document contains summary information on the latest projections from the IHME model on COVID-19

South-East Asia Region PROJECTIONS AND SCENARIOS

Figure 21. The estimated intensive care unit (ICU) usage is shown over time. The percent of ICU bedsoccupied by COVID-19 patients is color coded based on observed quantiles of the maximum proportion ofICU beds occupied by COVID-19 patients. Less than 10% is considered low stress, 10-29% is consideredmoderate stress, 30-59% is considered high stress, and greater than 60% is considered extreme stress.

Thailand

Sri Lanka

Nepal

Myanmar

Maldives

Indonesia

India

Bangladesh

Apr 20 Jun 20 Aug 20 Oct 20 Dec 20 Feb 21 Apr 21 Jun 21

Stress level

Low

Moderate

High

Extreme

Intensive care unit beds

covid19.healthdata.org 19 Institute for Health Metrics and Evaluation

Page 21: COVID-19 Results Briefing€¦ · The South-East Asia Region February 20, 2021 This document contains summary information on the latest projections from the IHME model on COVID-19

South-East Asia Region MORE INFORMATION

More informationData sources:

Mask use data sources include PREMISE; Facebook Global symptom survey (This research is based onsurvey results from University of Maryland Social Data Science Center) and the Facebook United Statessymptom survey (in collaboration with Carnegie Mellon University); Kaiser Family Foundation; YouGovCOVID-19 Behaviour Tracker survey.

Vaccine hesitancy data are from the COVID-19 Beliefs, Behaviors, and Norms Study, a survey conducted onFacebook by the Massachusetts Institute of Technology (https://covidsurvey.mit.edu/).

Data on vaccine candidates, stages of development, manufacturing capacity, and pre-purchasing agreementsare primarily from Linksbridge and supplemented by Duke University.

A note of thanks:

We wish to warmly acknowledge the support of these and others who have made our COVID-19 estimationefforts possible.

More information:

For all COVID-19 resources at IHME, visit http://www.healthdata.org/covid.

Questions? Requests? Feedback? Please contact us at https://www.healthdata.org/covid/contact-us.

covid19.healthdata.org 20 Institute for Health Metrics and Evaluation