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CRANIAL NERVE NUCLEI - LECTURE A. NBIO 401 – Wednesday, October 3, 2012. Objective for the first two cranial nerve lectures, those about cranial nerve nuclei : -Be able to summarize the function and location of each cranial nerve nucleus. Cranial Nerve Nuclei Introductory Organization. I. - PowerPoint PPT Presentation
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CRANIAL NERVE NUCLEI - LECTURE A
NBIO 401 – Wednesday, October 3, 2012
Objective for the first two cranial nerve lectures, those about cranial nerve nuclei:
-Be able to summarize the function and location of each cranial nerve nucleus.
Cranial Nerve Nuclei Introductory
Organization
V
VI
VIIVIII
IXX
XII
III
I
Optic Nerve II
V
VI
VIIVIII
IXX
XII
III
I
Optic Nerve IIONLY III - XII
V
VI
VIIVIII
IXX
XII
III
I
Optic Nerve IICRANIAL NERVE NUCLEI A = III - V
V
VI
VIIVIII
IXX
XII
III
I
Optic Nerve II
CRANIAL NERVE NUCLEI B = VI - XII
MesencephalicTrigeminal V
(jaw muscle spindles)
Main SensoryTrigeminal V
(face touch & proprioception)
Spinal Trigeminal V(face pain)
Vestibular/Cochlear
VIII(vestibular & auditory
signals from the inner ear)
Oculomotor III(eye muscles)
Trochlear IV(eye muscles)
Abducens VI(eye muscles)
Hypoglossal XII(tongue muscles)
SensoryGSA and SSA
MotorGSE
GENERAL SOMATICCRANIAL NERVE NUCLEI
Solitarius (caudal half)VII, IX, X
(sensory informationfor autonomic control)
Edinger-Westphal III(constricts pupil - parasympathetic)
Superior salivatory VII(drives salivary glands -
parasympathetic)
Inferior salivatory IX(drives salivary glands -
parasympathetic)
Dorsal motor n. of X(parasympathetic drive tosmooth muscles & organs
in chest and abdomen)
SensoryGVA
MotorGVE
GENERAL VISCERALCRANIAL NERVE NUCLEI
Solitarius (rostral half)VII, IX, X
(taste)
Motor Trigeminal V(chewing muscles)
Facial VII(muscles of
facial expression)
n. Ambiguus IX, X(muscles of the
pharynx & larynx)
SensorySVA
MotorSVE
SPECIAL VISCERALCRANIAL NERVE NUCLEI
sulcus limitans(divides motor nuclei [medial] and
sensory nuclei (lateral]).
sulcus limitans(divides motor nuclei [medial] and sensory nuclei (lateral]).
sulcus limitans
Motor nuclei locations
General Somatic Efferents lie close to the midline
General Visceral Efferents lay laterally to the General Somatic Efferents
Cranial Nerve Nuclei III-V
The Oculomotor (IIIrd) Nucleus
Oculomotor nucleus(motoneurons for
eye muscles)
Oculomotor nerve(to eye muscles & pupil muscles)
Edinger Westphal nucleus(constricts the pupil)
General Somatic Efferents lie close to the midline
MesencephalicTrigeminal V
(jaw muscle spindles)
Main SensoryTrigeminal V
(face touch & proprioception)
Spinal Trigeminal V(face pain)
Vestibular/Cochlear
VIII(vestibular & auditory
signals from the inner ear)
Oculomotor III(eye muscles)
Trochlear IV(eye muscles)
Abducens VI(eye muscles)
Hypoglossal XII(tongue muscles)
SensoryGSA and SSA
MotorGSE
GENERAL SOMATICCRANIAL NERVE NUCLEI
Cranial Nerve Nuclei
The Trochlear (IVth) Nucleus
QuickTime™ and aGIF decompressor
are needed to see this picture. Trochlear nerve(to eye muscles)
Trochlear nucleus(motoneurons for
eye muscles)
General Somatic Efferents lie close to the midline
MesencephalicTrigeminal V
(jaw muscle spindles)
Main SensoryTrigeminal V
(face touch & proprioception)
Spinal Trigeminal V(face pain)
Vestibular/Cochlear
VIII(vestibular & auditory
signals from the inner ear)
Oculomotor III(eye muscles)
Trochlear IV(eye muscles)
Abducens VI(eye muscles)
Hypoglossal XII(tongue muscles)
SensoryGSA and SSA
MotorGSE
GENERAL SOMATICCRANIAL NERVE NUCLEI
Cranial Nerve Nuclei III-V The
Trigeminal Nuclei
SensoryAxons signals for conscious
touch & muscle spindle/joint receptors(cell body in ganglion outside CNS)
SensoryAxons of 1° sensory neuron
for unconscious musclespindle & joint receptors
(cell body in mesencephalictrigeminal nucleus - the only
1° sensory cell body inside CNS)
To Thalamus
SensoryAxons signals for pain & temperature(cell body in ganglion outside CNS)
MotorAxons carrying motor signals to jaw muscles
(cell body motor trigeminal nucleus)
Trigeminal nerve
(sensory & motor
axons of 4 types
listed to the right)
Mesencephalic trigeminal nucleus (1° sensory neurons for
muscle spindles &joint receptors in head)
Mesencephalic trigeminal tract (axons bringing
unconscioussignals from muscle
spindles & joints in head)
Main sensorytrigeminal nucleus
Trigeminal nerve
Spinaltrigeminalnucleus
Motortrigeminalnucleus
Spinal trigeminal nucleus(pain & temperature from head)
Motor trigeminal nucleus(motoneurons for jaw muscles)
Main sensory trigeminal nucleus(touch, conscious
spindle & joint from head)
Trigeminal nerve(afferent: touch, muscle spindle/joint,
pain & temperature from headefferent: chewing muscles)
Main sensorytrigeminal nucleus
(left)
MotorTrigeminal
Nucleus(right)
Mesencephalic trigeminal tract
(left)
Mesencephalictrigeminal nucleus
(left)
Spinal trigeminal nerve (left)(1° axons on way to
terminate inspinal trigeminal nucleus)
Main sensorytrigeminal nucleus
(right)
SpinalTrigeminal
Nucleus(right)
TrigeminalNerve(left)
TrigeminalNerve(right)
Spinal trigeminal nucleus
(left)
Special Visceral (Branchial) Efferents lie most lateral of the motor nuclei.
Solitarius (rostral half)VII, IX, X
(taste)
Motor Trigeminal V(chewing muscles)
Facial VII(muscles of
facial expression)
n. Ambiguus IX, X(muscles of the
pharynx & larynx)
SensorySVA
MotorSVE
SPECIAL VISCERALCRANIAL NERVE NUCLEI
Mediallemniscus
Spinothalamictract
PyramidalTract
MedialLongitudinalFasciculus
PontineGray matter
SuperiorCerebellarpeduncle
Mesencephalic trigeminaltract & nucleus
ROSTRAL PONS
Mediallemniscus
Spinothalamictract
PyramidalTract
MiddleCerebellarpeduncle
MLF
PontineGray matter
Motor trigeminalnucleus
Superior cerebellar peduncle
Trigeminal nerve( sensory & motor
for the head)
Mesencephalic trigeminal tract & nucleus(muscle spindles from chewing muscles
& jaw joint receptors)
MID PONS
Mediallemniscus
Spinothalamictract
PyramidalTract
MiddleCerebellarpeduncle MLF
PontineGray matter
Superior cerebellar peduncle(fibers coming out of cerebellum)
Main sensory trigeminalNucleus (face touch)
Motor nucleusof trigeminal
(chewing musclemotoneurons)
Spinal trigeminaltract & nucleus
MID PONS
Mediallemniscus
SpinothalamicTract
PyramidalTract
Spinal trigeminalnucleus & tract
Abducens Nucleus(eye muscle
motoneurons)
Vestibularnuclei
MiddleCerebellarpeduncle
MLF
PontineGray matter
Inferiorcerebellarpeduncle
Facial nerve fibers(looping around abducens nucleus)
Facial motornucleus
CAUDAL PONS
Cuneate Fasciculus(touch-arm)
Pyramidal Decussation(corticospinal fiberscrossing midline)
SpinothalamicTract
(body pain)
Spinocerebellar Tract(sensory fibers - Muscle
spindle& joint information to
cerebellum - leg)Pyramids(corticospinal fibers)
Spinaltrigeminal
nucleus & tract(head pain & temp)
Cuneate Nucleus
(touch-arm)
Gracile Nucleus
(touch-leg)
Gracile Fasciculus(touch-leg)
Centralcanal
Medial LongitudinalFasciculus (MLF)
(vestibular & oculomotor information)
Spinal AccessoryNucleus
(motoneurons fortrapezius &
sternocleidomastoidmuscles)
Fini