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Page 1: Cremona, Italy - ULisboanews.fm.ul.pt/Backoffice/UserFiles/File/News36/IMM... · The lymphoid and immune system . T helper cells . Activate B cells and . macrophages . Cytotoxic T
Page 2: Cremona, Italy - ULisboanews.fm.ul.pt/Backoffice/UserFiles/File/News36/IMM... · The lymphoid and immune system . T helper cells . Activate B cells and . macrophages . Cytotoxic T

Cremona, Italy

Page 3: Cremona, Italy - ULisboanews.fm.ul.pt/Backoffice/UserFiles/File/News36/IMM... · The lymphoid and immune system . T helper cells . Activate B cells and . macrophages . Cytotoxic T

Opportunity and a challenge for composers

Page 4: Cremona, Italy - ULisboanews.fm.ul.pt/Backoffice/UserFiles/File/News36/IMM... · The lymphoid and immune system . T helper cells . Activate B cells and . macrophages . Cytotoxic T

Johann Sebastian Bach 1685-1750

Antonio Vivaldi 1678-1741

Page 5: Cremona, Italy - ULisboanews.fm.ul.pt/Backoffice/UserFiles/File/News36/IMM... · The lymphoid and immune system . T helper cells . Activate B cells and . macrophages . Cytotoxic T

Convergence in life sciences

Disciplinary integration

a new knowledge base new diagnostics

new therapeutics

Page 6: Cremona, Italy - ULisboanews.fm.ul.pt/Backoffice/UserFiles/File/News36/IMM... · The lymphoid and immune system . T helper cells . Activate B cells and . macrophages . Cytotoxic T

The lymphoid and immune system

T helper cells

Activate B cells and macrophages

Cytotoxic T cells

Kill virus infected cells

Lymphocytes

Plasma cells

Produce antibodies

Platforms for immune responses within the human body

Page 7: Cremona, Italy - ULisboanews.fm.ul.pt/Backoffice/UserFiles/File/News36/IMM... · The lymphoid and immune system . T helper cells . Activate B cells and . macrophages . Cytotoxic T

Engineering and the instruments

Imaging technology

Page 8: Cremona, Italy - ULisboanews.fm.ul.pt/Backoffice/UserFiles/File/News36/IMM... · The lymphoid and immune system . T helper cells . Activate B cells and . macrophages . Cytotoxic T
Page 9: Cremona, Italy - ULisboanews.fm.ul.pt/Backoffice/UserFiles/File/News36/IMM... · The lymphoid and immune system . T helper cells . Activate B cells and . macrophages . Cytotoxic T
Page 10: Cremona, Italy - ULisboanews.fm.ul.pt/Backoffice/UserFiles/File/News36/IMM... · The lymphoid and immune system . T helper cells . Activate B cells and . macrophages . Cytotoxic T

Engineering “firefly” cells

for the understanding of cell behaviour

Page 11: Cremona, Italy - ULisboanews.fm.ul.pt/Backoffice/UserFiles/File/News36/IMM... · The lymphoid and immune system . T helper cells . Activate B cells and . macrophages . Cytotoxic T

Cell migration and the instrument

Page 12: Cremona, Italy - ULisboanews.fm.ul.pt/Backoffice/UserFiles/File/News36/IMM... · The lymphoid and immune system . T helper cells . Activate B cells and . macrophages . Cytotoxic T

Mathematics and the in silico world

Computational biology

Page 13: Cremona, Italy - ULisboanews.fm.ul.pt/Backoffice/UserFiles/File/News36/IMM... · The lymphoid and immune system . T helper cells . Activate B cells and . macrophages . Cytotoxic T

Cell convergence

Page 14: Cremona, Italy - ULisboanews.fm.ul.pt/Backoffice/UserFiles/File/News36/IMM... · The lymphoid and immune system . T helper cells . Activate B cells and . macrophages . Cytotoxic T
Page 15: Cremona, Italy - ULisboanews.fm.ul.pt/Backoffice/UserFiles/File/News36/IMM... · The lymphoid and immune system . T helper cells . Activate B cells and . macrophages . Cytotoxic T

new language skills for new generations

Page 16: Cremona, Italy - ULisboanews.fm.ul.pt/Backoffice/UserFiles/File/News36/IMM... · The lymphoid and immune system . T helper cells . Activate B cells and . macrophages . Cytotoxic T

<50µm >50µm

Cell migration

Page 17: Cremona, Italy - ULisboanews.fm.ul.pt/Backoffice/UserFiles/File/News36/IMM... · The lymphoid and immune system . T helper cells . Activate B cells and . macrophages . Cytotoxic T

Computational modelling

Page 18: Cremona, Italy - ULisboanews.fm.ul.pt/Backoffice/UserFiles/File/News36/IMM... · The lymphoid and immune system . T helper cells . Activate B cells and . macrophages . Cytotoxic T

In silico

Adhesion time (seconds)

A Te

st S

core

Chemokine threshold

Ex vivo

Computational modelling

Page 19: Cremona, Italy - ULisboanews.fm.ul.pt/Backoffice/UserFiles/File/News36/IMM... · The lymphoid and immune system . T helper cells . Activate B cells and . macrophages . Cytotoxic T

Convergent technologies will extend research frontiers in the decades to come

Willingness to fund risky research to capitalize on the next revolution in life sciences

Page 20: Cremona, Italy - ULisboanews.fm.ul.pt/Backoffice/UserFiles/File/News36/IMM... · The lymphoid and immune system . T helper cells . Activate B cells and . macrophages . Cytotoxic T

RIKEN, Japan Centre for Developmental Biology